1. GPCR/G Protein
  2. GLP Receptor
  3. GLP-1 receptor agonist 10

GLP-1 receptor agonist 10 (compound 42) is an agonist of GLP Receptor. GLP-1 receptor agonist 10 inhibits food intake and reduces glucose excursion in mice. GLP-1 receptor agonist 10 can be used in the study of type 2 diabetes (T2DM) and obesity.

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GLP-1 receptor agonist 10 Chemical Structure

GLP-1 receptor agonist 10 Chemical Structure

CAS No. : 3015555-46-8

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
USD 608 In-stock
Solution
10 mM * 1 mL in DMSO USD 608 In-stock
Solid
5 mg USD 440 In-stock
10 mg USD 700 In-stock
25 mg USD 1450 In-stock
50 mg USD 2350 In-stock
100 mg USD 3750 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

GLP-1 receptor agonist 10 (compound 42) is an agonist of GLP Receptor. GLP-1 receptor agonist 10 inhibits food intake and reduces glucose excursion in mice. GLP-1 receptor agonist 10 can be used in the study of type 2 diabetes (T2DM) and obesity[1].

Molecular Weight

628.57

Formula

C30H28F4N6O5

CAS No.
Appearance

Solid

Color

Off-white to yellow

SMILES

FC(F)(F)C1=CC=C(COC2=CC=CC(N3C=NN(CC4=NC(C(F)=CC(C(O)=O)=C5)=C5N4C[C@@H]6CCO6)CC3)=N2)C(OC)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (198.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5909 mL 7.9546 mL 15.9091 mL
5 mM 0.3182 mL 1.5909 mL 3.1818 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.51%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5909 mL 7.9546 mL 15.9091 mL 39.7728 mL
5 mM 0.3182 mL 1.5909 mL 3.1818 mL 7.9546 mL
10 mM 0.1591 mL 0.7955 mL 1.5909 mL 3.9773 mL
15 mM 0.1061 mL 0.5303 mL 1.0606 mL 2.6515 mL
20 mM 0.0795 mL 0.3977 mL 0.7955 mL 1.9886 mL
25 mM 0.0636 mL 0.3182 mL 0.6364 mL 1.5909 mL
30 mM 0.0530 mL 0.2652 mL 0.5303 mL 1.3258 mL
40 mM 0.0398 mL 0.1989 mL 0.3977 mL 0.9943 mL
50 mM 0.0318 mL 0.1591 mL 0.3182 mL 0.7955 mL
60 mM 0.0265 mL 0.1326 mL 0.2652 mL 0.6629 mL
80 mM 0.0199 mL 0.0994 mL 0.1989 mL 0.4972 mL
100 mM 0.0159 mL 0.0795 mL 0.1591 mL 0.3977 mL
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GLP-1 receptor agonist 10 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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GLP-1 receptor agonist 10
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