2. Apoptosis Neuronal Signaling Membrane Transporter/Ion Channel Metabolic Enzyme/Protease Anti-infection Others
  3. Bacterial Endogenous Metabolite Apoptosis iGluR Isotope-Labeled Compounds
  4. Linalool-d6

Linalool-d6 is deuterated labeled Trans-Anethole (HY-N0367). Trans-Anethole ((E)-Anethole), a phenylpropene derivative isolated from Foeniculum vulgare, shows estrogenic activity at lower concentrations and cytotoxic at higher concentrations in cancer cell lines. Trans-Anethole ((E)-Anethole) contributes a large component of the odor and flavor of anise and fennel, anise myrtle, liquorice, camphor, magnolia blossoms, and star anise.

For research use only. We do not sell to patients.

Linalool-d<sub>6</sub> Chemical Structure

Linalool-d6 Chemical Structure

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Linalool-d6 Related Antibodies

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Description

Linalool-d6 is deuterated labeled Trans-Anethole (HY-N0367). Trans-Anethole ((E)-Anethole), a phenylpropene derivative isolated from Foeniculum vulgare, shows estrogenic activity at lower concentrations and cytotoxic at higher concentrations in cancer cell lines[1][2]. Trans-Anethole ((E)-Anethole) contributes a large component of the odor and flavor of anise and fennel, anise myrtle, liquorice, camphor, magnolia blossoms, and star anise[3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
Linalool (0-2000 μM, 24-72 h) can induce apoptosis of cancer cells (U87-MG, HepG-2, SW620 and so on) through oxidative stress while protecting normal cells PC12[4].
Linalool (0-2000 mg/mL, 0-72 h) exerts antibacterial effects by damaging cell membranes[4].
Linalool (0-2 mM, 24-48 h) inhibits A549 cell proliferation by inducing G0/G1 and/or G2/M cell cycle arrest, and without affecting the cell viability of normal lung WI-38 cells. Linalool inhibits A549 cell migration[5].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Linalool-d6 Related Antibodies
In Vivo

Linalool (150, 200, 250 mg/kg orally every alternate day for 21 days) reduces tumor growth by 50% in the S-180 solid tumor mouse model, inhibits oxidation in normal liver, and promotes oxidation in tumor tissue[6].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

160.29

Formula

C10H12D6O
SMILES

C=CC(O)(C)CC/C=C(C([2H])([2H])[2H])/C([2H])([2H])[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Linalool-d6 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Linalool-d6BacterialEndogenous MetaboliteApoptosisiGluRIsotope-Labeled CompoundsIonotropic glutamate receptorsInhibitorinhibitorinhibit

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