Martinostat hydrochloride

Cat. No.: HY-160092A Purity: 99.01%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Martinostat (hydrochloride) is a inhibitor of HDAC that can be labeled with radionuclides for diagnostic applications.

For research use only. We do not sell to patients.

Martinostat hydrochloride Chemical Structure

Size	Price	Stock	Quantity
5 mg	USD 120	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 190	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 360	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 590	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 950	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Martinostat (hydrochloride) is a inhibitor of HDAC that can be labeled with radionuclides for diagnostic applications^[1]^[2].

Molecular Weight

390.95

Formula

C₂₂H₃₁ClN₂O₂

Appearance

Solid

Color

Off-white to pink

SMILES

CN(CC(C=C1)=CC=C1/C=C/C(NO)=O)CC2(C[C@@H](C3)C4)C[C@@H]4C[C@@H]3C2.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (319.73 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.5579 mL	12.7894 mL	25.5787 mL
5 mM	0.5116 mL	2.5579 mL	5.1157 mL
10 mM	0.2558 mL	1.2789 mL	2.5579 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Dosing volume
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μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.01%

Select Batch:

Data Sheet (266 KB) SDS (251 KB)

COA (245 KB) HNMR (270 KB) LCMS (96 KB)

Handling Instructions (2659 KB)

References

[1]. Changning Wang, et al. In Vivo Imaging of Histone Deacetylases (HDACs) in the Central Nervous System and Major Peripheral Organs. J Med Chem. 2014 Oct 9;57(19):7999-8009. [Content Brief]

[2]. Tharick A Pascoal, et al. [11C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer’s disease. Nat Commun. 2022 Jul 19;13(1):4171. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.5579 mL	12.7894 mL	25.5787 mL	63.9468 mL
	5 mM	0.5116 mL	2.5579 mL	5.1157 mL	12.7894 mL
	10 mM	0.2558 mL	1.2789 mL	2.5579 mL	6.3947 mL
	15 mM	0.1705 mL	0.8526 mL	1.7052 mL	4.2631 mL
	20 mM	0.1279 mL	0.6395 mL	1.2789 mL	3.1973 mL
	25 mM	0.1023 mL	0.5116 mL	1.0231 mL	2.5579 mL
	30 mM	0.0853 mL	0.4263 mL	0.8526 mL	2.1316 mL
	40 mM	0.0639 mL	0.3197 mL	0.6395 mL	1.5987 mL
	50 mM	0.0512 mL	0.2558 mL	0.5116 mL	1.2789 mL
	60 mM	0.0426 mL	0.2132 mL	0.4263 mL	1.0658 mL
	80 mM	0.0320 mL	0.1599 mL	0.3197 mL	0.7993 mL
	100 mM	0.0256 mL	0.1279 mL	0.2558 mL	0.6395 mL