2. Academic Validation
  3. Development of a potent benzonitrile-based inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with antitumor efficacy

Development of a potent benzonitrile-based inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with antitumor efficacy

  • Signal Transduct Target Ther. 2023 Dec 15;8(1):454. doi: 10.1038/s41392-023-01715-x.
Lei Yu # 1,  Pengcheng Zhao # 1,  Yaoliang Sun # 2,  Zening Zheng # 1,  Wenhao Du 2,  Lishan Zhang 2,  Yaxu Li 1,  Longyan Xie 1,  Shilin Xu 3,  Ping Wang 4
Affiliations

Affiliations

  • 1 Tongji University Cancer Center, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
  • 2 Department of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • 3 Department of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. [email protected].
  • 4 Tongji University Cancer Center, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China. [email protected].
  • # Contributed equally.
PMID: 38097557 DOI: 10.1038/s41392-023-01715-x
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