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  3. Methyl Paraben-13C6

Methyl Paraben-13C6  (Synonyms: Methyl 4-hydroxybenzoate-13C6)

Cat. No.: HY-N0349S1 Purity: 99.90%
COA Handling Instructions

Methyl Paraben-13C6 (Methyl 4-hydroxybenzoate-13C6) is a 13C labeled Methyl Paraben (HY-N0349). Methyl Paraben, isolated from the barks of Tsuga dumosa the methyl ester of p-hydroxybenzoic acid, is a standardized chemical allergen. Methyl Paraben is a stable, non-volatile compound used as an antimicrobial preservative in foods, agents and cosmetics. The physiologic effect of Methyl Paraben is by means of increased histamine release, and cell-mediated immunity.

For research use only. We do not sell to patients.

Methyl Paraben-<sup>13</sup>C<sub>6</sub> Chemical Structure

Methyl Paraben-13C6 Chemical Structure

CAS No. : 1581694-95-2

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1 mg USD 633 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Methyl Paraben-13C6 (Methyl 4-hydroxybenzoate-13C6) is a 13C labeled Methyl Paraben (HY-N0349)[1]. Methyl Paraben, isolated from the barks of Tsuga dumosa the methyl ester of p-hydroxybenzoic acid, is a standardized chemical allergen. Methyl Paraben is a stable, non-volatile compound used as an antimicrobial preservative in foods, agents and cosmetics. The physiologic effect of Methyl Paraben is by means of increased histamine release, and cell-mediated immunity[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

158.10

Formula

C213C6H8O3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(OC)[13C]1=[13CH][13CH]=[13C](O)[13CH]=[13CH]1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (632.51 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.3251 mL 31.6256 mL 63.2511 mL
5 mM 1.2650 mL 6.3251 mL 12.6502 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.90%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 6.3251 mL 31.6256 mL 63.2511 mL 158.1278 mL
5 mM 1.2650 mL 6.3251 mL 12.6502 mL 31.6256 mL
10 mM 0.6325 mL 3.1626 mL 6.3251 mL 15.8128 mL
15 mM 0.4217 mL 2.1084 mL 4.2167 mL 10.5419 mL
20 mM 0.3163 mL 1.5813 mL 3.1626 mL 7.9064 mL
25 mM 0.2530 mL 1.2650 mL 2.5300 mL 6.3251 mL
30 mM 0.2108 mL 1.0542 mL 2.1084 mL 5.2709 mL
40 mM 0.1581 mL 0.7906 mL 1.5813 mL 3.9532 mL
50 mM 0.1265 mL 0.6325 mL 1.2650 mL 3.1626 mL
60 mM 0.1054 mL 0.5271 mL 1.0542 mL 2.6355 mL
80 mM 0.0791 mL 0.3953 mL 0.7906 mL 1.9766 mL
100 mM 0.0633 mL 0.3163 mL 0.6325 mL 1.5813 mL
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Methyl Paraben-13C6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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