2. GPCR/G Protein Neuronal Signaling
  3. Neuropeptide Y Receptor
  4. Neuropeptide Y (3-36) (porcine)

Neuropeptide Y (3-36) (porcine) is an agonist of neuropeptide Y (NPY) receptor subtype Y2, and stimulates feeding in rats. Neuropeptide Y (3-36) (porcine) is a highly Y2 selective ligand compared with nselective Y1/Y2 receptor ligand, Neuropeptide Y 1-36.

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Neuropeptide Y (3-36) (porcine) Chemical Structure

Neuropeptide Y (3-36) (porcine) Chemical Structure

CAS No. : 143863-88-1

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Neuropeptide Y (3-36) (porcine) Related Antibodies

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Description

Neuropeptide Y (3-36) (porcine) is an agonist of neuropeptide Y (NPY) receptor subtype Y2, and stimulates feeding in rats. Neuropeptide Y (3-36) (porcine) is a highly Y2 selective ligand compared with nselective Y1/Y2 receptor ligand, Neuropeptide Y 1-36[1][2][3].

IC50 & Target[3]

NPY Y2 receptor

 

In Vitro

Neuropeptide Y (3-36) (porcine) accounts for 35% of NPY-like immunoreactivity in porcine brain[2].
  Neuropeptide Y (3-36) (porcine) shows high affinity for Y2-like receptors on CHP234 cells, and light affinity Y1-like receptors on SK-N-MC cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Neuropeptide Y (3-36) (porcine) Related Antibodies
In Vivo

Neuropeptide Y (3-36) (porcine) (0.24-24 nM; i.c.v.; single dose) induces feeding in the rat in a dose-dependent manner[1].
Neuropeptide Y (3-36) (porcine) (4 μg, 8 μg; i.c.v.; single dose) significantly increased food intake at 2 and 3 h, results dose-dependently orexigenic effect in rainbow trout (Oncorhynchus mykiss)[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Adult male Wistar rats (250-300 g)[1]
Dosage: 0.24, 0.72, 2.4, 7.2, 24 nM per animal
Administration: Intracerebroventricular injection; single dose
Result: Stimulated rat feeding dose-dependently.
Produced no feeding effect alone, that Y2 activation alone elicited no feeding response.
Molecular Weight

3993.36

Formula

C176H271N53O54
CAS No.
Sequence Shortening

SKPDNPGEDAPAEDLARYYSALRHYINLITRQRY-NH2
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Purity & Documentation
References
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Neuropeptide Y (3-36) (porcine) Related Classifications

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  • Do most proteins show cross-species activity?

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Keywords:

Neuropeptide Y (3-36) (porcine)143863-88-1Neuropeptide Y ReceptorNPY receptorneuropeptide YNPYfeedingorexigenic effectY2-like receptorsCHP234 cellsY1-like receptorsSK-N-MC cellsInhibitorinhibitorinhibit

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