2. Immunology/Inflammation
  3. PD-1/PD-L1
  4. Pacmilimab

Pacmilimab  (Synonyms: CX-072)

Cat. No.: HY-P99799 Purity: 95.00%
COA

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Pacmilimab (CX-072) is a potent PD-L1 inhibitor. Pacmilimab shows antitumor activity.

For research use only. We do not sell to patients.

Pacmilimab Chemical Structure

Pacmilimab Chemical Structure

CAS No. : 2145091-51-4

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Description

Pacmilimab (CX-072) is a potent PD-L1 inhibitor. Pacmilimab shows antitumor activity[1].

Isotype

Human IgG4 kappa
Recommend Isotype Controls
Species

Human
In Vivo

Pacmilimab induces antitumor responses comparable to those of the same dose of the parental antibody in mice bearing MC38 tumors[1].
Pacmilimab accumulates in murine PD-L1-expressing tumors with minimal uptake in peripheral, non-cancerous lymphoid tissue, consistent with limited uptake in non-tumor PD-L1-expressing tissues and protection against autoimmunity[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Pacmilimab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

Purity: 95.00%

COA (231 KB)

Handling Instructions (2659 KB)
References
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Pacmilimab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pacmilimab2145091-51-4CX-072CX072CX 072PD-1/PD-L1PD-1/Programmed death-ligand 1Inhibitorinhibitorinhibit

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