2. Neuronal Signaling
  3. Monoamine Oxidase
  4. (R)-Safinamide

(R)-Safinamide  (Synonyms: FCE 28073; (R)-EMD 1195686)

Cat. No.: HY-14203 Purity: 99.88%
COA Handling Instructions

Molarity Calculator

(R)-Safinamide, the enantiomer of safinamide (HY-70057), can inhibit MAO-B with an IC50 value of 0.45 μM.

For research use only. We do not sell to patients.

(R)-Safinamide Chemical Structure

(R)-Safinamide Chemical Structure

CAS No. : 174756-44-6

Size Price Stock Quantity
5 mg USD 65 In-stock
10 mg USD 97 In-stock
25 mg USD 165 In-stock
50 mg USD 230 In-stock
100 mg USD 320 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of (R)-Safinamide:

(R)-Safinamide Related Antibodies

Top Publications Citing Use of Products

View All Monoamine Oxidase Isoform Specific Products:

View All Isoforms

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

(R)-Safinamide, the enantiomer of safinamide (HY-70057), can inhibit MAO-B with an IC50 value of 0.45 μM[1].

IC50 & Target

IC50: 0.45 μM (MAO-B)[1].
Molecular Weight

302.34

Formula

C17H19FN2O2
CAS No.
Unlabeled CAS

Appearance

Solid

SMILES

FC1=CC=CC(COC2=CC=C(C=C2)CN[C@@H](C(N)=O)C)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 125 mg/mL (413.44 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3075 mL 16.5377 mL 33.0753 mL
5 mM 0.6615 mL 3.3075 mL 6.6151 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3075 mL 16.5377 mL 33.0753 mL 82.6884 mL
5 mM 0.6615 mL 3.3075 mL 6.6151 mL 16.5377 mL
10 mM 0.3308 mL 1.6538 mL 3.3075 mL 8.2688 mL
15 mM 0.2205 mL 1.1025 mL 2.2050 mL 5.5126 mL
20 mM 0.1654 mL 0.8269 mL 1.6538 mL 4.1344 mL
25 mM 0.1323 mL 0.6615 mL 1.3230 mL 3.3075 mL
30 mM 0.1103 mL 0.5513 mL 1.1025 mL 2.7563 mL
40 mM 0.0827 mL 0.4134 mL 0.8269 mL 2.0672 mL
50 mM 0.0662 mL 0.3308 mL 0.6615 mL 1.6538 mL
60 mM 0.0551 mL 0.2756 mL 0.5513 mL 1.3781 mL
80 mM 0.0413 mL 0.2067 mL 0.4134 mL 1.0336 mL
100 mM 0.0331 mL 0.1654 mL 0.3308 mL 0.8269 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

(R)-Safinamide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(R)-Safinamide174756-44-6FCE 28073 (R)-EMD 1195686FCE28073FCE-28073Monoamine OxidaseMAOSafinamideParkinson's diseaseInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
(R)-Safinamide
Cat. No.:
HY-14203
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.