2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. DNA/RNA Synthesis Cytochrome P450
  4. S-(N-PhenethylthiocarbaMoyl)-L-cysteine

S-(N-PhenethylthiocarbaMoyl)-L-cysteine  (Synonyms: PEITC-Cys)

Cat. No.: HY-115754
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S-(N-PhenethylthiocarbaMoyl)-L-cysteine (PEITC-Cys), an anticarcinogenic agent, has antileukemic activity. S-(N-PhenethylthiocarbaMoyl)-L-cysteine inhibits DNA synthesis in HL60 cells. S-(N-PhenethylthiocarbaMoyl)-L-cysteine is a P450 inhibitor.

For research use only. We do not sell to patients.

S-(N-PhenethylthiocarbaMoyl)-L-cysteine Chemical Structure

S-(N-PhenethylthiocarbaMoyl)-L-cysteine Chemical Structure

CAS No. : 53330-02-2

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S-(N-PhenethylthiocarbaMoyl)-L-cysteine Related Antibodies

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Description

S-(N-PhenethylthiocarbaMoyl)-L-cysteine (PEITC-Cys), an anticarcinogenic agent, has antileukemic activity. S-(N-PhenethylthiocarbaMoyl)-L-cysteine inhibits DNA synthesis in HL60 cells[1]. S-(N-PhenethylthiocarbaMoyl)-L-cysteine is a P450 inhibitor[2].

IC50 & Target

DNA Synthesis[1]; P450[2]
In Vitro

S-(N-PhenethylthiocarbaMoyl)-L-cysteine inhibits cell growth of HL60 cell (GC50=336 nM)[1].
S-(N-PhenethylthiocarbaMoyl)-L-cysteine inhibits DNA synthesis in HL60 cells (IC50=6.47 μM)[1].
S-(N-PhenethylthiocarbaMoyl)-L-cysteine induced DNA fragmentation in HL 60 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

S-(N-PhenethylthiocarbaMoyl)-L-cysteine Related Antibodies

Cell Proliferation Assay[1]

Cell Line: HL60 cells
Concentration: 0.1-10 μM
Incubation Time: 48 hours
Result: Inhibited the cell growth with a GC50 value of 336 nM.

Cell Proliferation Assay[1]

Cell Line: HL60 cells
Concentration: 4 μM
Incubation Time: 0, 20, 40, 60, 80, 100 hours
Result: Inhibited the cell growth.
Molecular Weight

284.40

Formula

C12H16N2O2S2
CAS No.
SMILES

N[C@@H](CSC(NCCC1=CC=CC=C1)=S)C(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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S-(N-PhenethylthiocarbaMoyl)-L-cysteine Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

S-(N-PhenethylthiocarbaMoyl)-L-cysteine53330-02-2PEITC-CysDNA/RNA SynthesisCytochrome P450CYPsDNA fragmentationDNA synthesisHL60 cellcancerantileukemicInhibitorinhibitorinhibit

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