Search Result
Results for "
insects
" in MedChemExpress (MCE) Product Catalog:
3
Biochemical Assay Reagents
22
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-B0841
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- HY-B1575
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Others
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Others
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Butopyronoxyl is an insect repellent that can be mainly used to repel mosquitoes .
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-
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- HY-133620
-
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Others
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Infection
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7-Oxodehydroabietic acid is a diterpene resin acid isolated from the roots of the pine Pinus densiflora. 7-Oxodehydroabietic acid play a defensive role against herbivorous insects via insect endocrine-disrupting activity .
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-
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- HY-145297
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-
- HY-125982
-
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Others
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Others
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VUAA1 is an insect odorant co-receptor (Orco) agonist. VUAA1 activates both heteromeric and homomeric Orco-containing channels. VUAA1 can disrupt the destructive behaviors of nuisance insects. VUAA1 can be used for insect olfactory research .
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-
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- HY-N2548
-
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Others
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Cardiovascular Disease
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Turkesterone is a potent ecdysteroid. Turkesterone acts as an ecdysteroid receptor (EcR) agonist in some insect systems .
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-
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- HY-N1133
-
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Parasite
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Infection
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trans-Methylisoeugenol is an insect chemosterilant isolated from Acorus calamus L .
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-
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- HY-129243
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Others
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Others
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Uredepa is an insect chemosterilant. Uredepa can be used for the research of various biochemical studies .
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-
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- HY-119335
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S-2703
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Sodium Channel
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Others
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Cyphenothrin (S-2703) is a pyrethroid pesticide. Cyphenothrin acts on the neuromuscular system of insects, intervening in the gating mechanism of sodium channels .
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-
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- HY-N7267
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Others
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Endocrinology
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31-Norlanostenol is a triterpenic compound isolated from the latex of Euphorbia officinarum. 31-Norlanostenol can act as efficient insect growth regulator on S. frugiperda and Tenebrio molitor .
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-
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- HY-P5140
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Calcium Channel
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Metabolic Disease
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ω-Tbo-IT1 is a peptide toxin that can be isolated from the venom of Tibellus oblongus.ω-Tbo-IT1 is an inhibitor of insect calcium channel .
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-
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- HY-136612
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Drug Metabolite
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Others
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DCBA is a metabolite of insect repellent N-N-diethyl-meta-toluamide (DEET). The concentration of DCBA in urine can assess exposure to DEET .
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-
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- HY-155334
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Others
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Others
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RyRs activator 4 (compound B18) is an insect ryanodine receptor activator. RyRs activator 4 has a larvicidal activity of Mythimna separata with an LC50 value of 1.32 mg/L .
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-
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- HY-B1946
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Others
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Others
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Dimethoate is an effective systemic insecticide for use on plants, has shown promise as a chemotherapeutic agent for control of cattle grubs and certain other insect pests of farm animals, and has high contact toxicity to house-flies and many other insects .
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-
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- HY-B1072A
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(-)-trans-Phenothrin
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Parasite
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Infection
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D-Phenothrin ((-)-trans-Phenothrin), an orally active Type II synthetic pyrethroid, is widely used to kill insects, mosquitoes, and human lice. D-Phenothrin is also used in veterinary medicine to control insect pests on animals and protect agricultural crops .
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- HY-B1161
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Methoprene
Maximum Cited Publications
11 Publications Verification
ZR-515
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Others
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Others
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Methoprene, an insect juvenile growth hormone mimic, is a growth-regulating insecticide that manifests its toxicity to target organisms by acting as a juvenile hormone agonist .
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- HY-118730
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Andalin; DU 319722; A 1335
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Others
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Infection
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Flucycloxuron (Andalin) is an insect growth regulator (IGR) .
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-
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- HY-147107
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Others
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Others
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OfHex1-IN-2 (compound I-79) is a potent β-N-acetylhexosaminidase OfHex1 inhibitor. OfHex1-IN-2 can be used in control of insect .
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-
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- HY-W338247
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Others
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Others
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Imidaclothiz is a kind of neonicotinoid insecticides. Imidaclothiz has excellent insecticidal effect. Imidaclothiz can be used for the research of sucking and biting insects .
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- HY-113890
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RH-0345
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Others
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Others
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Halofenozide (RH-0345) is an ecdysteroid agonist. RH-0345 belongs to a new group of insect growth regulators (IGRs) with a benzoylhydrazine structure that mimic the action of the natural insect molting hormone 20-hydroxyecdysone .
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- HY-149864
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Others
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Others
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Insecticidal agent 3 is a multichitinase inhibitors, belongs to insect growth regulators (IGRs),with Kis of 0.8μM, 11.9 μM, and 2.3 μM for Of ChtI, Of ChtII, and Of Chi-h, respectively. Insecticidal agent 3 exhibits insecticidal activity against two lepidopteran pests by interfering with normal insect growth and molting .
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- HY-14620A
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Others
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Others
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Farnesene (mixture of isomers) is a farnesene with mixture of isomers. Farnesene is a herbivore-induced plant volatile (HIPV). Farnesene has an important effect on insect resistance in many plant species .
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- HY-N3694
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Desacetyl nimbin
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Others
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Others
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Deacetylnimbin is a limonoid isolated from Azadirachta indica. Deacetylnimbin can be used as a plant metabolite, a food repellent and as a growth regulator for insects such as S. litura, P. ricini and O. fscovittata .
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- HY-P3655
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Calcium Channel
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Others
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Agelenin is a polypeptide composed of 35 amino acids. Agelenin could be isolated from the Agelenidae spider Agelena opulenta. Agelenin has structural similarity to insect-specific calcium channel inhibitor .
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- HY-P10390
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Parasite
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Infection
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Insecticidal agent 11 (compound Q6) is a potent insect growth regulator (IGR)-based insecticide. Insecticidal agent 11 shows high insecticidal activity against Diploptera punctata by inhibiting juvenile hormone (JH) biosynthesis. Insecticidal agent 11 also exhibits insecticidal activity against Plutella xylostella .
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- HY-16974
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GABA Receptor
Chloride Channel
Parasite
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Infection
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Afoxolaner is an orally active isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect γ-aminobutyric acid receptor (GABA) and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod .
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- HY-W010607
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(Z)-3-Hexen-1-ol
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Others
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Neurological Disease
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cis-3-Hexen-1-ol ((Z)-3-Hexen-1-ol) is a green grassy smelling compound found in many fresh fruits and vegetables. cis-3-Hexen-1-ol is widely used as an added flavor in processed food to provide a fresh green quality. cis-3-Hexen-1-ol is an attractant to various insects .
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- HY-W017423
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Cholinesterase (ChE)
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Neurological Disease
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(-)-Carvone is an insect neurotoxin and a irreversible acetylcholinesterase (AChE) inhibitor. (-)-Carvone can be used as a bird repellent, inhibits larval growth, decreases pupatation rate, and increases mortality of larvae .
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- HY-B0840
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Parasite
Oxidative Phosphorylation
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Metabolic Disease
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Chlorfenapyr is a pyrrole insecticide. Chlorfenapyr has a mode of action: the mixed function oxidase oxidizes and removes the Nethoxymethyl group to form the active metabolite, CL 303268. Chlorfenapyr is used for termite control and crop protection against a variety of insect and mite pests .
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- HY-110381
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Acyltransferase
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Metabolic Disease
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JNJ-DGAT2-A is a selective diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 value of 0.14 μM in human DGAT2-expressing Sf9 insect cell membranes. JNJ-DGAT2-A can be used for the research of triglyceride (TG) synthesis .
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- HY-N7677
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HSV
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Infection
Inflammation/Immunology
Cancer
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Isookanin can be used for the research of various illnesses including cancers, skin rashes, snake and insects bites, diabetes mellitus, diarrhoea. Isookanin acts as an anti-viral agent against HSV and varicella-zoster virus (VZV). Antioxidant activity .
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- HY-153732
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Parasite
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Infection
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Insecticidal agent 2 (example 2) is a pesticide that exhibits potent growth-retarding activity against pests .
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- HY-P3035
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G Protein-coupled Receptor Kinase (GRK)
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Neurological Disease
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Corazonin is a highly conserved neuropeptide hormone of wide-spread occurrence in insects, serves a central regulator of caste identity and behavior in social insects. Corazonin is also preferentially expressed in workers and/or foragers from other social insect species .
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- HY-B0978S
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DEET-d10; N,N-Diethyl-m-toluamide-d10
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Parasite
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Infection
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Diethyltoluamide-d10 is the deuterium labeled Diethyltoluamide[1]. Diethyltoluamide is the most common active ingredient in insect repellents. It is intended to provide protection against mosquitoes, ticks, fleas, chiggers, leeches, and many other biting insects[2].
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- HY-B0978S1
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DEET-d7; N,N-Diethyl-m-toluamide-d7
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Parasite
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Infection
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Diethyltoluamide-d7 is the deuterium labeled Diethyltoluamide[1]. Diethyltoluamide is the most common active ingredient in insect repellents. It is intended to provide protection against mosquitoes, ticks, fleas, chiggers, leeches, and many other biting insects[2].
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- HY-B1946S
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Isotope-Labeled Compounds
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Others
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Dimethoate-d6 is the deuterium labeled Dimethoate. Dimethoate is an effective systemic insecticide for use on plants, has shown promise as a chemotherapeutic agent for control of cattle grubs and certain other insect pests of farm animals, and has high contact toxicity to house-flies and many other insects[1].
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- HY-B0820
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nAChR
Parasite
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Neurological Disease
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Nitenpyram is a calss of neonicotinoid and an insect nicotinic acetylcholine receptor (nAChR) agonist with an IC50 of 14 nM. Nitenpyram is an oral fast-acting insecticide used to suppress sucking insects on companion animals .
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- HY-122940
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Others
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Others
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Precocene II is the insect antijuvenile hormone .
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- HY-P0268
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-
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- HY-W087988
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Bacterial
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Infection
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3-Pentanol is an active organic compound produced by plants and is a component of emitted insect sex pheromones. 3-pentanol elicits plant immunity against microbial pathogens and an insect pest in crop plants .
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- HY-B1331S
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Endogenous Metabolite
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Neurological Disease
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Cyromazine-d4 is the deuterium labeled Cyromazine. Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects.
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- HY-B1094
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2-Chloro-4-nitrobenzamide
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Parasite
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Infection
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Aklomide is used to fight disease, parasites and insects that infest poultry.
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- HY-B1331
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-
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- HY-B1331S1
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Cyromazin-13C3; CGA-72662-13C3
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Isotope-Labeled Compounds
Endogenous Metabolite
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Neurological Disease
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Cyromazine- 13C3 is the 13C3 labeled Cyromazine. Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects.
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- HY-145299
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nAChR
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Infection
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nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator .
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- HY-145300
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nAChR
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Infection
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nAChR modulator-2, a insecticide, is a insect nAChR orthosteric modulator .
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- HY-121263
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Others
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Cancer
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Dicyclanil is an insect growth regulator compound with a similar chemical structure to cyromazine .
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- HY-W040149
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Others
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Others
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Tetramethrin is a synthetic pyrethroid insecticide for use on a broad spectrum of insect pests .
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- HY-B0820R
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nAChR
Parasite
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Neurological Disease
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Nitenpyram (Standard) is the analytical standard of Nitenpyram. This product is intended for research and analytical applications. Nitenpyram is a calss of neonicotinoid and an insect nicotinic acetylcholine receptor (nAChR) agonist with an IC50 of 14 nM. Nitenpyram is an oral fast-acting insecticide used to suppress sucking insects on companion animals .
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- HY-W131296
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Others
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Endocrinology
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Ethyl 4-Methyloctanoate is an insect pheromone isolated from various sources .
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- HY-17519
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Others
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Others
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Novaluron is a chemical with pesticide properties, belonging to the class of insecticides called insect growth regulators.
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- HY-N7493
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NADA
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Endogenous Metabolite
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Others
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N-acetyldopamine (NADA) is a catecholamine that is used by insects as sclerotizing precursors to harden their cuticle .
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- HY-N7592
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Others
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Others
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Arjunetin, isolated from Terminalia arjuna, is an insect feeding-deterrent and growth inhibitor .
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- HY-W749562
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Others
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Endocrinology
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Gossyplure is an insect pheromone used for capturing male pink bollworm moths and corn earworms .
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- HY-N10040
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Others
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Others
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Poststerone is a nature product. Poststerone is a metabolite of insect metamorphosing substances from Cyathula capata .
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- HY-W780813
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Others
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Endocrinology
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(Z)-3-Decenol is an insect sex pheromone that specifically attracts male beetles .
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- HY-N4294
-
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Others
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Metabolic Disease
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Arjungenin, a triterpene isolated from Terminalia arjuna, is an insect feeding-deterrent and growth inhibitor .
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- HY-136394
-
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Others
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Others
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Diafenthiuron is a thiourea compound commonly used pesticide. Diafenthiuron inhibits mitochondrial functioning in insect pests .
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- HY-117484
-
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Others
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Others
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Rubrosterone is a metabolite of insect metamorphosing substances, that can be isolated from Achyranthes rubrofuca and A. fmaiei (Amaranthaceae) .
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- HY-B0978
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DEET; N,N-Diethyl-m-toluamide
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Parasite
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Infection
Neurological Disease
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Diethyltoluamide (DEET) is the most common active ingredient in insect repellents. It is intended to provide protection against mosquitoes, ticks, fleas, chiggers, leeches, and many other biting insects. Diethyltoluamide is toxic to hepatocytes and can lead to many physiological, pharmacological, and behavioral abnormalities, particularly motor deficits and learning and memory dysfunction .
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- HY-W087988S
-
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Bacterial
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Infection
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3-Pentanol-d5 is the deuterium labeled 3-Pentanol[1]. 3-Pentanol is an active organic compound produced by plants and is a component of emitted insect sex pheromones. 3-pentanol elicits plant immunity against microbial pathogens and an insect pest in crop plants[2].
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- HY-B1812S
-
-
- HY-B1812S2
-
-
- HY-B1812S3
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- HY-N11502
-
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Others
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Others
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(E)-(-)-Aspongopusamide B (Compound 9) is a natural product that can be isolated from the insect Aspongopus chinensis .
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- HY-W777963
-
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Others
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Endocrinology
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(2E)-Octadecenal is a female pheromone targeting Lepidoptera insects, isolated from female Tineola bisselliella .
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- HY-101552B
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o,o'-Dityrosine hydrochloride
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Others
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Others
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L,L-Dityrosine hydrochloride (o,o'-Dityrosine hydrochloride) is a constituent of acid hydrolysates of a number of biological materials, including the insect cuticular resilin .
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- HY-101552A
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o,o'-Dityrosine
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Others
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Others
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L,L-Dityrosine (o,o'-Dityrosine) is a constituent of acid hydrolysates of a number of biological materials, including the insect cuticular resilin .
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- HY-N1284
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(-)-Seneganolide
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Others
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Others
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Seneganolide (compound 1) is isolated from the stem bark of Khaya senegalensis. Seneganolide can be used as insect antifeedant .
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- HY-B0887
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NRDC-143
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Parasite
|
Infection
|
Permethrin (NRDC-143) is an insecticide, acaricide, and insect repellent; functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation.
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- HY-B1120
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Temefos
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Parasite
|
Infection
|
Temefos is an organophosphate larvicide, used to treat water infested with disease-carrying insects including mosquitoes, midges, and black fly larvae.
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- HY-B0827
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MTI-446
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nAChR
Parasite
|
Infection
|
Dinotefuran is an insecticide of the neonicotinoid class, its mechanism of action involves disruption of the insect's nervous system by inhibiting nicotinic acetylcholine receptors.
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- HY-N7179
-
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Others
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Others
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7-Hydroxy-5-methoxycoumarin is a phloroglucinol-type furocoumarins, a potent naturally-occurring insect antifeedant .
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- HY-N12924
-
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Others
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Endocrinology
|
Ethyl 3-octenoate is an insect sex pheromone capable of attracting male Mediterranean fruit flies (Ceratitis capitata Wied.) .
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- HY-N12932
-
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Others
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Endocrinology
|
(E)-10-Dodecenyl acetate is an insect sex pheromone used for attracting soybean pod borers (Leguminivora glyinivorella (Matsumura)) .
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- HY-W745644
-
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Others
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Endocrinology
|
(Z)-7-Hexadecenal is a sex pheromone that attracts male insects, isolated from female Heliothis virescens moths .
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- HY-N7145
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Isobombycol
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Others
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Endocrinology
|
Bombykol, the first insect sex pheromone, is identified as the female-produced sex attractant of the silkworm moth Bombyx mori .
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- HY-N3184
-
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Others
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Others
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N-Methylflindersine is a compound isolated as insect antifeedants from the East African Rutaceous medicinal plants Fagara chalybea and F. holtziana .
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- HY-B1812S1
-
-
- HY-114502
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NSC 11779
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Others
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Others
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Chrysanthemic acid (NSC 11779) is an organic compound that is associated with a variety of natural and synthetic insecticides for the prevention of insect-borne diseases, among others .
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- HY-119592
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-
- HY-B2009
-
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Others
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Others
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Flufenoxuron is a chitin synthesis inhibitor that is used as a benzoylurea insecticide. Flufenoxuron decreases chitin synthesis, molting, and egg hatching, preventing development in insects .
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-
- HY-W075176
-
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Others
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Others
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Transfluthrin is a fast-acting pyrethroid insecticide and mosquito repellent. Transfluthrin is against flying insects, such as mosquito and flies, and in agriculture material pests .
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- HY-N12895
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(Z,Z)-Gossyplure
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Others
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Endocrinology
|
(Z)-7,11-Hexadecadienyl acetate is a female sex pheromone used to attract male insects, isolated from Plutella xylostella .
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-
- HY-P3570
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Lom-AKH-II
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Endogenous Metabolite
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Metabolic Disease
|
Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs) .
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- HY-P3572
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Lom-AKH-I
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Endogenous Metabolite
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Endocrinology
|
Adipokinetic hormone I (Locusta migratoria) (Lom-AKH-I) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs) .
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- HY-W778834
-
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Others
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Endocrinology
|
(Z)-13-Octadecen-1-ol is an insect sex pheromone used for trapping sugarcane stem borers (Chilo sacchariphagus) .
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-
- HY-W040149R
-
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Others
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Others
|
Tetramethrin (Standard) is the analytical standard of Tetramethrin. This product is intended for research and analytical applications. Tetramethrin is a synthetic pyrethroid insecticide for use on a broad spectrum of insect pests .
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-
- HY-N12113
-
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Others
|
Infection
|
9-(Z)-Pentacosene is a olefin that can be isolated from Fannia canicularis. 9-(Z)-Pentacosene has anti-insect activity .
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-
- HY-125326
-
|
Parasite
|
Infection
|
Spinosyn D is one of the major components of Spinosad (HY-138800). Spinosad is a natural pesticide that shows biological activity against a range of insects including Lepidoptera .
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-
- HY-W009165
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cis-9-Tricosene
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Others
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Others
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(Z)-9-Tricosene (cis-9-Tricosene) is an insect pheromone present in flies of the order Diptera (such as the housefly) and can be used as an insecticide .
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-
- HY-W674057
-
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Others
|
Endocrinology
|
(Z)-3-Dodecen-1-ol is an insect sex pheromone capable of attracting male sweet potato weevils (Cylas formicarius elegantulus) .
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- HY-116564
-
|
Parasite
GABA Receptor
|
Infection
|
Lotilaner is a parasiticide, acts as a potent non-competitive antagonist of insects GABACl receptors, with an IC50 of 23.84 nM for Drosophila melanogaster GABA receptor. No effect on a dog GABAA receptor .
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- HY-14620
-
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Others
|
Others
|
α-Farnesene is classified as a sesquiterpene, and is a herbivore-induced plant volatile (HIPV). α-Farnesene has an important effect on insect resistance in many plant species .
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-
- HY-W780784
-
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Others
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Endocrinology
|
(Z,Z)-3,13-Octadecadien-1-ol is an insect sex pheromone used for trapping redwood resin borers (Synanthedon sequoiae (Edwards)) .
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-
- HY-B0887S1
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NRDC-143-d9
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Isotope-Labeled Compounds
Parasite
|
Infection
|
Permethrin-d9 is the deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide, and insect repellent; functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation.
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-
- HY-N3980
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Champacol; Guaiac alcohol
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Autophagy
|
Infection
Cancer
|
Guaiol is a sesquiterpene alcohol that has been found in several traditional Chinese medicinal plants and has antiproliferative, pro-autophagic, insect repellent, and insecticidal biological activities .
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-
- HY-128701
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(9E,12Z)-9,12-Tetradecadien-1-ol acetate
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Others
|
Others
|
(9E,12Z)-Tetradecadien-1-yl acetate is the main component of pheromone of insects Ephestia Kuehniella and Plodia Interpunctella, and cereal pests .
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-
- HY-P1602
-
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Bacterial
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Infection
|
Apidaecin IB is a insect antimicrobial peptide, with minimum inhibitory concentration (MIC) values of 8 μM for E. coli (ML35, O18K1H7 and ATCC 25922).
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-
- HY-136560
-
|
Drug Metabolite
|
Others
|
6-Azathymine acid is a metabolite of Pymetrozine. Pymetrozine is active against plant-sucking insects, such as aphids and whiteflies in vegetables, cotton, field crops and fruits and affects the nervous regulation of feeding behavior .
|
-
- HY-118504
-
|
nAChR
|
Neurological Disease
|
Sulfoxaflor is a sulfoximine insecticide and is an agonist of nAChR1 and nAChR2 subtypes. Sulfoxaflor is used for the control of sap-feeding insects such as Myzus persicae, Aphis gossypii, Bemissia tabaci and Nilaparvata lugens .
|
-
- HY-N10100
-
|
Others
|
Others
|
Epiglobulol is a natural product that can be isolated from Atalantia buxifolia. Epiglobulol is a principal components of essential oil which has significant contact toxicity against three stored-product insects .
|
-
- HY-B0887C
-
1R-cis-NRDC-143
|
Parasite
|
Infection
|
1R-cis-Permethrin is an insecticide and neurotoxin. 1R-cis-Permethrin affects neuron membranes by prolonging sodium channel activation .
|
-
- HY-N12934
-
|
Others
|
Endocrinology
|
Z13,YN11-16:OH (7) is an insect pheromone used for attracting and trapping processionary caterpillars (Thaumetopoea processionea L), effective against oak defoliators .
|
-
- HY-111664
-
(+)-Citronellal
|
Endogenous Metabolite
|
Metabolic Disease
|
(R)-(+)-Citronellal, isolated from citrus, lavender and eucalyptus oils, is a monoterpenoid and main component of citronellal oil with a distinct lemon scent. A flavouring agent. Used for insect repellent and antifungal properties .
|
-
- HY-N6994
-
|
Others
|
Infection
|
Isoasatone A is a natural product isolated from the plant Heterotropa takaoi M., with anti-insect activity. Isoasatone A againsts S. litura by acting on cytochrome P450 monoxygenases and glutathione transferases .
|
-
- HY-W052234
-
|
Others
|
Others
|
4-Fluorophenoxyacetic acid (4FPA) induces parthenocarpy. 4-Fluorophenoxyacetic acid (4FPA) protects cereals from piercing-sucking insects and thereby increases rice yield in the field .
|
-
- HY-B2054
-
|
Apoptosis
|
Others
|
Tebufenozide is a nonsteroidal ecdysone agonist used to control pest. Tebufenozide has cytotoxic and induces apoptosis in HeLa and insect Tn5B1-4 cells .
|
-
- HY-108689
-
|
GABA Receptor
|
Neurological Disease
|
Broflanilide is a potential insecticide and metabolized to Desmethyl-Broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin (RDL) GABA Receptor, and inhibits S. litura RDL GABAR, with an IC50 value of 1.3 nM .
|
-
- HY-N12210
-
|
Parasite
|
Others
|
Notrilobolide is an alkaloid with insecticidal properties isolated from sweet potatoes. Notrilobolide has an inhibitory effect on the larval development of pests such as Tribolium Castaneum, affecting the digestion and reproduction of insects by inhibiting the fecundity of pests .
|
-
- HY-N12933
-
|
Bacterial
|
Endocrinology
|
11-Octadecenal is a volatile oil isolated from antibacterial components of coumarin, which can be isolated from synthetic insect sex pheromones used for attracting wax moths (Achroia grisella) .
|
-
- HY-N12937
-
|
Others
|
Endocrinology
|
(Z)-7-Decenyl acetate is a synthetic insect sex pheromone used for attracting turnip moths (Agrotis segetum), which can be isolated from analogs with lower activity than natural pheromones .
|
-
- HY-18598
-
|
Others
|
Infection
|
Chitinase-IN-1 is a insect chitinase and N- acetyl hexosaminidase inhibitor and pesticide; 50 uM/20 uM compound concentration's inhibitory percentage are 75%/67% for chitinase/N- acetyl-hexosaminidase respectively.
|
-
- HY-18599
-
|
Others
|
Others
|
Chitinase-IN-2 is a insect chitinase and N- acetyl hexosaminidase inhibitor and pesticide; 50 μM/20 μM compound concentration's inhibitory percentage are 98%/92% for chitinase/N- acetyl-hexosaminidase respectively.
|
-
- HY-B0834
-
(±)-Indoxacarb; DPX-JW062
|
Sodium Channel
|
Neurological Disease
|
Indoxacarb ((±)-Indoxacarb; DPX-JW062) is a broad-spectrum oxadiazine insecticide with high insecticidal activity and low mammalian toxicity. Indoxacarb blocks insect sodium channels (Sodium Channel) in nerve preparations and isolated neurons .
|
-
- HY-148968
-
Carbathion
|
Fungal
|
Infection
|
Metham sodium (Carbathion) is a broad-spectrum soil microbial suppressant. Metham sodium controls soil-borne pests and weeds. Metham sodium inhibits weed seeds, plant-parasitic nematodes, plant pathogenic fungi and soil insects .
|
-
- HY-N12938
-
|
Others
|
Endocrinology
|
(Z)-7-Hexadecenyl acetate is a pheromone used for capturing male tobacco budworm moths (Heliothis virescens), which can be isolated from the brush glands or hair pencils on the abdomen or hind wings of insects .
|
-
- HY-18599A
-
|
Others
|
Others
|
Chitinase-IN-2 hydrochloride is a insect chitinase and N- acetyl hexosaminidase inhibitor and pesticide; 50 uM/20uM compound concentration's inhibitory percentage are 98%/92% for chitinase/N- acetyl-hexosaminidase respectively.
|
-
- HY-B1851
-
|
Parasite
|
Infection
|
Hexythiazox is a selective acaricide with ovicidal, larvicidal and nymphicidal activities. Hexythiazox is widely used for chemical control of mites on cotton, fruits and vegetables. Hexythiazox is harmless to mammals and has no effect on beneficial insects and predators of mites .
|
-
- HY-B0827S
-
MTI-446-d3
|
nAChR
Parasite
|
Infection
|
Dinotefuran-d3 is the deuterium labeled Dinotefuran[1]. Dinotefuran is an insecticide of the neonicotinoid class, its mechanism of action involves disruption of the insect's nervous system by inhibiting nicotinic acetylcholine receptors[2].
|
-
- HY-B1773A
-
|
Biochemical Assay Reagents
|
Others
|
Sodium Propionate is used as a food preservative, bakery product and as a mold inhibitor in insect cell cultures. It is also used as a preservative in pharmaceuticals, cosmetics, agriculture and animal feed. It is used as a food additive. In addition, it inhibits the growth of lactic acid bacteria.
|
-
- HY-W750129
-
|
Others
|
Endocrinology
|
(3E,8Z)-3,8-Tetradecadienyl acetate is an insect sex pheromone that can be isolated from unmated female South American potato tuber moths (Scrobipalpula absoluta) .
|
-
- HY-B1837
-
|
Sodium Channel
|
Infection
|
Cyfluthrin is a type II pyrethroid and has effects on various insects. Cyfluthrin is a modulator of Nav1.8 sodium channels by repetitive stimulation. Cyfluthrin can be applied in agriculture,veterinary, insecticide,pyrethroid and stored product .
|
-
- HY-N11667
-
|
Others
|
Infection
Cancer
|
18-O-Demethylpederin is a pederin analogue. Pederin is a natural polyketide compound extracted from Paederus for the first time. It is a non-protein insect toxin with a broad spectrum of biological activities, including antibacterial, antiviral, and antitumor .
|
-
- HY-B0825A
-
|
Parasite
Mitochondrial Metabolism
|
Infection
|
Fenpyroximate is an acaricide and insecticide against many mites and insect pests of agricultural crops and ornamentals. Fenpyroximate is also a strong inhibitor of bovine heart mitochondrial NADH-ubiquinone oxidoreductase (complex I), binds to the ND5 subunit .
|
-
- HY-117215
-
|
Biochemical Assay Reagents
|
Others
|
Beta-Ocimene is a naturally occurring organic compound that belongs to the terpene family. It exists as a mixture of three isomers: cis β-Ocimene, trans β-Ocimene and myrcene-like β-Ocimene. It has a pleasant, sweet herbaceous scent and is found in many plants, including mint, basil, parsley, and kumquat. β-Ocimene is widely used in the flavor and fragrance industry due to its characteristic aroma and taste. It also has potential applications in agriculture as natural insect repellants and pheromones that attract beneficial insects. β-Ocimene has potential anti-inflammatory and anticancer activities.
|
-
- HY-B1161S
-
ZR-515-d7
|
Isotope-Labeled Compounds
|
Others
|
Methoprene-d7 is the deuterium labeled Methoprene[1]. Methoprene, an insect juvenile growth hormone mimic, is a growth-regulating insecticide that manifests its toxicity to target organisms by acting as a juvenile hormone agonist[2][3].
|
-
- HY-125829
-
|
Others
|
Others
|
Erythropterin is a Pterin derivative that belongs in a group of heterocyclic compounds that are frequently found in biological systems. Pterin derivatives are responsible for the characteristic warning coloration of some Heteroptera and other insects, signaling noxiousness or unpalatability and are used to discourage potential predators from attacking .
|
-
- HY-N12879
-
(R)-10Me 14Me-15:iBu
|
Others
|
Endocrinology
|
(R)-10,14-Dimethylpentadecyl isobutyrate ((R)-10Me 14Me-15:iBu) is a female sex pheromone with insect electroantennographic (EGA) activity, isolated from tea tussock moth .
|
-
- HY-B0815
-
|
Cholinesterase (ChE)
|
Neurological Disease
|
Chlorpyrifos is a neurotoxic insecticide that belongs to the class of thionite esters. Chlorpyrifos is also a AChE inhibitor that affects neurological function in insects, humans and other animals. Chlorpyrifos interferes with cell replication and differentiation, ultimately altering synaptic transmission in neurons .
|
-
- HY-126741
-
|
Apoptosis
|
Others
|
Azadirachtin, one of the most promising botanical insecticides, is widely used for pest control. Azadirachtin induces apoptosis in insect cell lines, including Sf9, SL-1 and BTI-Tn-5B1-4 .
|
-
- HY-N7001
-
|
Bacterial
Fungal
|
Infection
|
Dehydrotomatine is a steroidal glycoalkaloid (SGA). α-tomatine and Dehydrotomatine accumulate in the mature green fruits, leaves, and flowers of tomatoes (Solanum lycopersicum) and function as defensive compounds against pathogens and predators. SGAs show toxic effects on fungi, bacteria, insects, and animals .
|
-
- HY-B0887S
-
NRDC-143-d5
|
Parasite
|
Infection
|
Permethrin-d5 (NRDC-143-d5) is the deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide, and insect repellent; functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation[1][2].
|
-
- HY-D1122
-
|
Fluorescent Dye
|
Others
|
Janus green B is a supravital stain. Janus green B staining reaction is oxygen dependent, and is reversibly inhibited by cyanide. Janus green B has been used for staining peripheral nerves in live insects, lymphatic vessels of rabbits and mitochondria .
|
-
- HY-P2825
-
TDC; TyrDC
|
Endogenous Metabolite
|
Metabolic Disease
|
Tyrosine decarboxylase, Microorganism (TDC) widely exists in plants, insects and different microorganisms, and is often used in biochemical research. Tyrosine decarboxylase is a pyridoxal 5'-phosphate (PLP)-dependent decarboxylase that catalyzes the removal of carboxyl groups from tyrosine to produce tyramine and carbon dioxide .
|
-
- HY-P5827
-
-
- HY-N12428
-
Caudicifolin; Fischeriana A
|
Others
|
Others
|
17-Hydroxyjolkinolide A (Caudicifolin; Fischeriana A) is an insect feeding inhibitor isolated from the roots of spurge. 17-Hydroxyjolkinolide A induces grain aversion in S. zeamais and T. castaneum adults, with EC50s of 631.9 ppm and 656.5 ppm, respectively.
|
-
- HY-136611
-
|
Drug Metabolite
|
Infection
|
ω-Hydroxy-DEET is a major metabolite of insect repellent N-N-diethyl-meta-toluamide (DEET). ω-Hydroxy-DEET has anti-proliferative effects. DEET is a spatial repellent and an irritant that commonly used to prevent contact with mosquitoes .
|
-
- HY-N1389
-
Carmine red
|
Fluorescent Dye
|
Inflammation/Immunology
Cancer
|
Carmine (Carmine red), a natural red dye extracted from the dried females of the insect Dactylopius coccus var. Costa (cochineal). Carmine is a widely used food additive. Carmine provokes both an immediate hypersensitivity and a delayed systemic response with cutaneous expression .
|
-
- HY-133167
-
|
Others
|
Others
|
Clothianidin is a neonicotinoid insecticide. Clothianidin shows excellent long-term control effect in small doses against various insect pests such as Coleoptera, Thysanoptera, Lepidoptera, Diptera, Homoptera, Heteroptera, Orthoptera and Isoptera families. Clothianidin has various application methods and high safety for crops .
|
-
- HY-121248
-
AC217300
|
Mitochondrial Metabolism
|
Infection
|
Hydramethylnon (AC217300) is an amidinohydrazone insecticide. Hydramethylnon's mechanism of action is through inhibition of mitochondrial respiration by inhibiting the electron transport chain at the cytochrome b-c1 complex. Hydramethylnon can be used to eliminate red imported fire ants, cockroaches, and other insects .
|
-
- HY-B1851S
-
|
Isotope-Labeled Compounds
Parasite
|
Infection
|
Hexythiazox-d11 is deuterium labeled Hexythiazox. Hexythiazox is a selective acaricide with ovicidal, larvicidal and nymphicidal activities. Hexythiazox is widely used for chemical control of mites on cotton, fruits and vegetables. Hexythiazox is harmless to mammals and has no effect on beneficial insects and predators of mites[1][2].
|
-
- HY-134645
-
Heneicosyl alcohol
|
Biochemical Assay Reagents
|
Others
|
1-Heneicosanol is a long-chain alcohol with 21 carbon atoms commonly used in the production of surfactants, lubricants and pharmaceuticals. It can be found in various natural sources such as vegetable waxes and insect pheromones. Additionally, it has been shown to be bioactive against plants and animals and has antimicrobial properties.
|
-
- HY-B2054S
-
|
Apoptosis
|
Others
|
Tebufenozide-d9 is the deuterium labeled Tebufenozide[1]. Tebufenozide is a nonsteroidal ecdysone agonist used to control pest. Tebufenozide has cytotoxic and induces apoptosis in HeLa and insect Tn5B1-4 cells[2][3].
|
-
- HY-149697
-
|
Parasite
|
Others
|
Insecticidal agent 6 (Compound Im) is an insect ryanodine receptors (RyRs) inhibitor, with an EC50 value of 0.6308 µM against S. frugiperda RyRs. Insecticidal agent 6 has excellent insecticidal activity against lepidopteran pests and can be used for research on pests and diseases .
|
-
- HY-163157
-
|
Parasite
|
Others
|
Insecticidal agent 7 (Compound 21m) is an insecticide that targets the insect ryanodine receptors (RyRs) with a LC50 of 0.0937 mg/L for the Plutella xylostella. Insecticidal agent 7 (Compound 21m) exhibits good selectivity and low toxicity towards non-target organisms .
|
-
- HY-B2054R
-
|
Apoptosis
|
Others
|
Tebufenozide (Standard) is the analytical standard of Tebufenozide. This product is intended for research and analytical applications. Tebufenozide is a nonsteroidal ecdysone agonist used to control pest. Tebufenozide has cytotoxic and induces apoptosis in HeLa and insect Tn5B1-4 cells .
|
-
- HY-B0640
-
WAL801
|
Histamine Receptor
|
Inflammation/Immunology
Endocrinology
|
Epinastine (WAL801) is an antihistamine and mast cell stabilizer. Epinastine is a potent, selective and orally-active histamine H1 receptor antagonist. Epinastine also inhibits IL-8 release and has an antiallergic action .
|
-
- HY-B0640A
-
WAL801 hydrochloride
|
Histamine Receptor
|
Inflammation/Immunology
Endocrinology
|
Epinastine hydrochloride (WAL801 hydrochloride) is an antihistamine and mast cell stabilizer. Epinastine hydrochloride is a potent, selective and orally-active histamine H1 receptor antagonist. Epinastine hydrochloride also inhibits IL-8 release and has an antiallergic action .
|
-
- HY-112820
-
|
Others
|
Others
|
Chlorantraniliprole is an insecticide that potently and selectively activates insect ryanodine receptor, with EC50s of 40 nM and 50 nM for Drosophila melanogaster and H. virescens ryanodine receptor, and ∼300-fold more potent than that in the mouse myoblast cell line, C2C12 (EC50, 14 μM).
|
-
- HY-W068430
-
|
Others
|
Others
|
5,7-Dimethoxy-2,2-dimethylchromene is a synthetic precocenoid, has potential insect control function. 5,7-Dimethoxy-2,2-dimethylchromene induces loss of pigmentation in hatching larvae of shield bug (Eurgaster integriceps) .
|
-
- HY-N12939
-
|
Others
|
Endocrinology
|
(11Z,13Z)-Hexadecadien-1-ol is an insect sex pheromone attractive to male navel orangeworm moths (Amyeloistransitella), a secretion of the moth Z11, which can be isolated from Z13-16:Ald analogs .
|
-
- HY-W780787
-
E3,Z13-18:Ac
|
Others
|
Endocrinology
|
(E,Z)-3,13-Octadecadienyl acetate (E3,Z13-18:Ac) is an insect sex pheromone that elicits attraction in male lesser peachtree borers (Lesser Peachtree Borer), which can be isolated from female lesser peachtree borers .
|
-
- HY-138800
-
|
nAChR
|
Neurological Disease
|
Spinosad, a mixture of spinosyns A and D known as fermentation products of a soil actinomycete (Saccharopolyspora spinosa), is a biological neurotoxic insecticide with a broader action spectrum. Spinosad targets the nicotinic acetylcholine receptor (nAChRs) of the insect nervous system. Spinosad has an excellent environmental and mammalian toxicological profile. Larvicidal activity .
|
-
- HY-100547
-
|
iGluR
|
Neurological Disease
|
IEM-1754, a dicationic adamantane derivative, is a potent blocker of open channels of native ionotropic glutamate receptors including quisqualate-sensitive receptors in insect muscles, NMDAR in cultured rat cortical neurons, and AMPAR in freshly isolated hippocampal cells. IEM-1754 shows anticonvulsant potency in vivo .
|
-
- HY-N2534
-
-
- HY-W747105
-
|
Others
|
Endocrinology
|
(2E,13Z)-Octadecadienyl acetate is an insect sex pheromone capable of attracting clearwing moths (Synanthedon tipul(formis (Clerck)) or raspberry crown borers (Pennisetia marginata (Harris)). (2E,13Z)-Octadecadienyl acetate can induce strong responses in male antennae .
|
-
- HY-B0816
-
|
Others
|
Others
|
Etofenprox is an orally active non-ester pyrethroid insecticide. Etofenprox induces toxicity against many pest insects, including Diptera rather than mammalian and fish. Etofenprox has a liver tumor-promoting activity in rats accompanied with microsomal ROS production increase. Etofenprox can be used in agricultural pest control and malaria research .
|
-
- HY-B1161A
-
(+)-Methoprene; (7S)-Methoprene
|
Cannabinoid Receptor
|
Others
|
S-Methoprene is an insect juvenile hormone analog and effective insecticide that blocks the transition from pupa to adult. S-Methoprene is also a CB(1) receptor ligand and inhibits the binding of the CB1 receptor antagonist [ 3H]CP-55940 to the CB1 receptor (IC50: 19.31 μM) .
|
-
- HY-15311
-
Abamectin; Avermectin B1a-Avermectin B1b mixt.
|
Parasite
Autophagy
Apoptosis
Reactive Oxygen Species
Antibiotic
|
Infection
Inflammation/Immunology
|
Avermectin B1 (Abamectin) is a mixture of two similar segments of avermectin. Avermectin B1 is an orally anti-infection agent, which can be used in the research of parasitic worms, insect pests, agriculture and animal husbandry. Avermectin B1 can also induce the production of ROS and induces cytotoxicity, apoptosis and autophagy .
|
-
- HY-N1944
-
|
Bacterial
Fungal
Parasite
Endogenous Metabolite
|
Infection
Cancer
|
Nerolidol has multiple natural membrane activities, possesses anti-cancer, anti-inflammatory, antibacterial and anti-insect activity. Nerolidol Suppresses parasitic activity, suppresses bloodsucking diseases, bloodworm diseases, and other diseases. Nerolidol can protect the cells from lipid and protein properties, damage to DNA, and protect the cells from damage .
|
-
- HY-N0179
-
α-Ecdysone
|
Endogenous Metabolite
Apoptosis
|
Metabolic Disease
|
Ecdysone (α-Ecdysone), a major steroid hormone in insects and herbs, triggers mineralocorticoid receptor (MR) activation and induces cellular apoptosis. Ecdysone plays essential roles in coordinating developmental transitions and homeostatic sleep regulation through its active metabolite 20-hydroxyecdysone (Crustecdysone; 20E; HY-N6979) .
|
-
- HY-B1120S
-
Temefos-d12
|
Parasite
|
Infection
|
Temephos-d12 is the deuterium labeled Temephos[1]. Temefos is an organophosphate larvicide, used to treat water infested with disease-carrying insects including mosquitoes, midges, and black fly larvae. Temefos affects the central nervous system through inhibition of cholinesterase, results in death before reaching the adult stage[2][3].
|
-
- HY-N12177
-
|
Phosphatase
|
Metabolic Disease
|
Cryptosporioptide A (Compound 3) is a pigment protein tyrosine phosphatase inhibitor derived from the insect-parasitic fungus Cordyceps gracilioides. Cryptosporioptide A inhibits PTP1B, SHP2, CDC25B, LAR and SHP1 enzymes with IC50 of 7.3, 5.7, 7.6, >50, 4.9 μg/mL, respectively .
|
-
- HY-B0815S
-
|
Cholinesterase (ChE)
|
Neurological Disease
|
Chlorpyrifos-d10 is the deuterium labeled Chlorpyrifos. Chlorpyrifos is an organophosphate insecticide that is classified as a phosphorothionate. The oxon metabolite of Chlorpyrifos is an inhibitor of acetylcholinesterase (AChE), affecting neurological function in insects, humans, and other animals. The Chlorpyrifos oxon (CPO) metabolite is hydrolyzed by the plasma enzyme paraoxonase 1 (PON1), and susceptibility to neurotoxicity associated with CPO exposure is mitigated by PON1 overexpression.
|
-
- HY-N3014
-
|
Notch
Apoptosis
Parasite
|
Infection
Cancer
|
Bruceine D is a Notch inhibitor with anti-cancer activity and induces apoptosis in several human cancer cells. Bruceine D is an effective botanical insect antifeedant with outstanding systemic properties, causing potent pest growth inhibitory activity . Bruceine D has strong anthelmintic activity against D. intermedius with an EC50 value of 0.57 mg/L .
|
-
- HY-N7058
-
|
Others
|
Others
|
Cis-Jasmone is a plant-derived natural product. Cis-Jasmone is constitutively released by many flowers and sometimes by leaves as an attractant for pollinators or as a chemical cue for host location by insect flower herbivores. Cis-Jasmone treatment of crop plants not only induces direct defense against herbivores, but also induces indirect defense by releasing VOCs that attract natural enemies .
|
-
- HY-157016
-
|
Others
|
Others
|
OfChi-h-IN-1 is a potent OfChi-h inhibitor with a Ki value of 0.33 μM. OfChi-h-IN-1 dramatically inhibit the growth and development of Ostrinia nubilalis larvae, and it shows higher insecticidal activity than Hexaflumuron (HY-B1848).?OfChi-h-IN-1 serves as novel candidates for insect growth regulator .
|
-
- HY-B1916
-
Spiramycin B; Spiramycin II; Foromacidin B
|
Antibiotic
Bacterial
Parasite
|
Infection
|
Acetylspiramycin (Spiramycin B) is an effective oral macrolide antibiotic produced by Streptomyces, It can inhibit the splenic lymphocyte transformation induced by phytohemagglutinin (PHA), LPS (HY-D1056) and antigen, reduce the procoagulant activity of macrophages, have good antibacterial effect on gram-positive bacteria, and is also an effective antigenic insect agent, which can be used to fight parasitic infection .
|
-
- HY-W008364
-
|
Cytochrome P450
Cannabinoid Receptor
|
Neurological Disease
|
Olivetol is a naturally phenol found in lichens and produced by certain insects, acting as a competitive inhibitor of the cannabinoid receptors CB1 and CB2 . Olivetol also inhibits CYP2C19 and CYP2D6 activity, with IC50s of 15.3 μM, 7.21 μM and Kis of 2.71 μM, 2.87 μM, respectively .
|
-
- HY-N6640
-
20-Hydroxyeedysone 2-acetate
|
Amyloid-β
|
Neurological Disease
|
2-O-Acetyl-20-hydroxyecdysone, an ecdysterones in insects and terrestrial plants, inhibits amyloid-β42 (Aβ42)-induced cytotoxicity. 2-O-Acetyl-20-hydroxyecdysone could decrease Aβ oligomer formation through promotion of fibrogenesis, transforming Aβ oligomers to the low-toxicity fibrils .
|
-
- HY-P10228
-
|
Fungal
Bacterial
|
Infection
|
S-Thanatin is an insect antimicrobial peptide with potent broad-spectrum antibacterial activity. S-Thanatin can inhibit the activity of Gram-negative bacteria, Gram-positive bacteria, and fungi, without cytotoxicity. The antibacterial activity of S-Thanatin is not affected by PH value, but monovalent cations (Na +/K +) can reduce its antibacterial activity against Gram-negative bacteria in a dose-dependent manner .
|
-
- HY-133167S
-
|
Isotope-Labeled Compounds
|
Others
|
Clothianidin-d3 is the deuterium labeled Clothianidin.Clothianidin-d3 is a neonicotinoid insecticide. Clothianidin-d3 shows excellent long-term control effect in small doses against various insect pests such as Coleoptera, Thysanoptera, Lepidoptera, Diptera, Homoptera, Heteroptera, Orthoptera and Isoptera families. Clothianidin-d3 has various application methods and high safety for crops .
|
-
- HY-W741191
-
|
Others
|
Endocrinology
|
(2E,13Z)-Octadecadienal is an insect sex pheromone capable of attracting clearwing moths (Synanthedon tipul(formis (Clerck)) or raspberry crown borers (Pennisetia marginata (Harris))). (2E,13Z)-Octadecadienal can be isolated from (2E,13Z)-Octadecadienyl acetate, which induces strong responses in male antennae .
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- HY-116144
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Lcaridin
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Parasite
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Infection
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Picaridin (Lcaridin) is a broad spectrum arthropod repellent. The repellent and deterrent activities of Picaridin involve olfactory sensing in mosquitoes, and ticks, via their interactions with odorant receptor proteins .
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- HY-16785
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INXN-1001; RG-115932
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Interleukin Related
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Inflammation/Immunology
Cancer
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Veledimex (INXN-1001), a synthetic analog of the insect molting hormone ecdysone, is an orally active activator ligand for a proprietary gene therapy promoter system. Veledimex can be used to activate certain genes using the ecdysone receptor (EcR)-based inducible gene regulation system, the RheoSwitch Therapeutic System (RTS). Veledimex can cross blood-brain barrier (BBB) in both orthotopic GL-261 mice and cynomolgus monkeys .
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- HY-N7125S
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Bacterial
Isotope-Labeled Compounds
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Others
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Cinnamyl acetate- 13C2 is 13C labeled Nerolidol (HY-N1944). Nerolidol has multiple natural membrane activities, possesses anti-cancer, anti-inflammatory, antibacterial and anti-insect activity. Nerolidol Suppresses parasitic activity, suppresses bloodsucking diseases, bloodworm diseases, and other diseases. Nerolidol can protect the cells from lipid and protein properties, damage to DNA, and protect the cells from damage .
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- HY-B0837
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MK-244
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Parasite
GABA Receptor
Reactive Oxygen Species
Apoptosis
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Infection
Neurological Disease
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Emamectin Benzoate (MK-244) is an orally active nervoussystem toxicant by binding g-aminobutyric (GABA) receptor in insects. Emamectin Benzoate is one of semi-synthetic derivative of Avermectin (HY-15311) with a broadspectrum of insecticidal and acaricidal activity. Emamectin Benzoate induces ROS-mediated DNA damage and cell apoptosis. Emamectin Benzoate, a mixture of the natural Emamectin B1a benzoate and Emamectin B1b benzoate, has the main component of Emamectin B1a benzoate .
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- HY-W017140S
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SBMP-d3
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Isotope-Labeled Compounds
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Others
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2-Sec-butyl-3-methoxypyrazine-d3 is deuterated labeled cis-?Jasmone (HY-N7058). Cis-Jasmone is a plant-derived natural product. Cis-Jasmone is constitutively released by many flowers and sometimes by leaves as an attractant for pollinators or as a chemical cue for host location by insect flower herbivores. Cis-Jasmone treatment of crop plants not only induces direct defense against herbivores, but also induces indirect defense by releasing VOCs that attract natural enemies .
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- HY-B0824
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Sodium Channel
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Neurological Disease
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Bifenthrin is a synthetic pyrethroid insecticide. Bifenthrin prolongs the opening time of Nav1.8 sodium channels, leading to membrane depolarization and conductance block in the insect nervous system, thereby disrupting neural function. Bifenthrin was effective in inhibiting A. gambiae (LD50=0.15 ng/mg) and C. quinquefasciatus (LD50=0.16 ng/mg). Bifenthrin has good lethality against susceptible and resistant mosquitoes and is very effective in inhibiting blood sucking and can be developed as a mosquito-removal netting material .
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- HY-B2049
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Others
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Infection
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Triflumuron is a potent chitin synthesis inhibitor. Triflumuron shows the efficacy in emergence inhibition (EI) against Culex quinquefasciatus and Aedes albopictus, with EI50 values of 5.28 and 1.59 μg/L, respectively. Triflumuron can be used as an insecticide. Triflumuron represents a potential tool for the control of disease vectors in public health .
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- HY-12795
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PI3K
Autophagy
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Cancer
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Vps34-IN-1 is a potent and selective inhibitor of class III Vps34 PI3K. Vps34-IN-1 inhibits phosphorylation of PtdIns by recombinant insect cell expressed Vps34-Vps15 complex with an IC50 of ~25 nM. Vps34-IN-1 can suppress SGK3 activation by reducing PtdIns(3)P levels via lowering phosphorylation of T-loop and hydrophobic motifs. Vps34-IN-1 modulates autophagy .
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- HY-B0837R
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MK-244 (Standard)
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Parasite
GABA Receptor
Reactive Oxygen Species
Apoptosis
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Infection
Neurological Disease
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Emamectin (Benzoate) (Standard) is the analytical standard of Emamectin (Benzoate). This product is intended for research and analytical applications. Emamectin Benzoate (MK-244) is an orally active nervoussystem toxicant by binding g-aminobutyric (GABA) receptor in insects. Emamectin Benzoate is one of semi-synthetic derivative of Avermectin (HY-15311) with a broadspectrum of insecticidal and acaricidal activity. Emamectin Benzoate induces ROS-mediated DNA damage and cell apoptosis. Emamectin Benzoate, a mixture of the natural Emamectin B1a benzoate and Emamectin B1b benzoate, has the main component of Emamectin B1a benzoate .
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- HY-B0822S1
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GABA Receptor
Cytochrome P450
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Inflammation/Immunology
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Fipronil- 13C6 is the 13C-labeled Fipronil. Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 30 nM and 1,600 nM for cockroach and rat receptors, respectively). Fipronil also inhibits desensitizing and non-desensitizing glutamate-induced chloride currents in cockroach neurons (IC50s = 800 nM and 10 nM, respectively). Fipronil induces activity of the cytochrome P450 (CYP) isoforms CYP1A1/2, CYP2B1/2, and CYP3A1/2 in isolated rat liver microsomes.
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Cat. No. |
Product Name |
Type |
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- HY-D1122
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Dyes
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Janus green B is a supravital stain. Janus green B staining reaction is oxygen dependent, and is reversibly inhibited by cyanide. Janus green B has been used for staining peripheral nerves in live insects, lymphatic vessels of rabbits and mitochondria .
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Cat. No. |
Product Name |
Type |
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- HY-B1773A
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Biochemical Assay Reagents
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Sodium Propionate is used as a food preservative, bakery product and as a mold inhibitor in insect cell cultures. It is also used as a preservative in pharmaceuticals, cosmetics, agriculture and animal feed. It is used as a food additive. In addition, it inhibits the growth of lactic acid bacteria.
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- HY-117215
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Biochemical Assay Reagents
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Beta-Ocimene is a naturally occurring organic compound that belongs to the terpene family. It exists as a mixture of three isomers: cis β-Ocimene, trans β-Ocimene and myrcene-like β-Ocimene. It has a pleasant, sweet herbaceous scent and is found in many plants, including mint, basil, parsley, and kumquat. β-Ocimene is widely used in the flavor and fragrance industry due to its characteristic aroma and taste. It also has potential applications in agriculture as natural insect repellants and pheromones that attract beneficial insects. β-Ocimene has potential anti-inflammatory and anticancer activities.
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- HY-134645
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Heneicosyl alcohol
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Biochemical Assay Reagents
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1-Heneicosanol is a long-chain alcohol with 21 carbon atoms commonly used in the production of surfactants, lubricants and pharmaceuticals. It can be found in various natural sources such as vegetable waxes and insect pheromones. Additionally, it has been shown to be bioactive against plants and animals and has antimicrobial properties.
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Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P3633
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Lom-TK II
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Peptides
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Neurological Disease
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Locustatachykinin II (Lom-TK II) is an insect neuropeptide with homology to peptides of the vertebrate tachykinin family. Locustatachykinin II can be used for the research of insect endocrine .
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- HY-P5140
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Calcium Channel
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Metabolic Disease
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ω-Tbo-IT1 is a peptide toxin that can be isolated from the venom of Tibellus oblongus.ω-Tbo-IT1 is an inhibitor of insect calcium channel .
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- HY-P4851
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Manse-AKH
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Peptides
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Others
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Adipokinetic Hormone (Apis mellifera ligustica, Bombyx mori, Heliothis zea, Manduca sexta) is a common peptide among various insects. Adipokinetic Hormone induces strong adipokinetic/hypertrehalosemic response. However Adipokinetic Hormone has no a glycogen-mobilizing function nor an adequate glycogen store in fat body for its effective utilization .
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- HY-P3655
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Calcium Channel
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Others
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Agelenin is a polypeptide composed of 35 amino acids. Agelenin could be isolated from the Agelenidae spider Agelena opulenta. Agelenin has structural similarity to insect-specific calcium channel inhibitor .
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- HY-P10390
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Parasite
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Infection
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Insecticidal agent 11 (compound Q6) is a potent insect growth regulator (IGR)-based insecticide. Insecticidal agent 11 shows high insecticidal activity against Diploptera punctata by inhibiting juvenile hormone (JH) biosynthesis. Insecticidal agent 11 also exhibits insecticidal activity against Plutella xylostella .
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- HY-P3635
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Pea-CAH-II
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Peptides
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Neurological Disease
Metabolic Disease
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Cockroach Myoactive Peptide II (Pea-CAH-II) is a cockroach neuropeptide. Cockroach Myoactive Peptide II is a member of the adipokinetic hormone/red pigment concentrating hormone (AKH/RPCH) family. Cockroach Myoactive Peptide II can be used for the research of metabolic functions of insect body .
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- HY-P3035
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G Protein-coupled Receptor Kinase (GRK)
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Neurological Disease
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Corazonin is a highly conserved neuropeptide hormone of wide-spread occurrence in insects, serves a central regulator of caste identity and behavior in social insects. Corazonin is also preferentially expressed in workers and/or foragers from other social insect species .
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- HY-P3630
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Peptides
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Others
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Stick Insect Hypertrehalosaemic Factor II is a synthetic peptide. Stick Insect Hypertrehalosaemic Factor II has the same FAB spectra, reversed-phase high-performance liquid chromatographic behavior, and biological behavior as the natural material. Stick Insect Hypertrehalosaemic Factor II can be used for the research of hypertrehalosaemic effect .
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- HY-P0268
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- HY-P1760
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Peptides
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Neurological Disease
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Allatostatin IV is an octapeptide. Allatostatins are pleiotropic neuropeptides for inhibition of juvenile hormone synthesis in insects .
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- HY-P1786
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Peptides
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Neurological Disease
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Allatostatin II is a decapeptid. Allatostatins are pleiotropic neuropeptides for inhibition of juvenile hormone synthesis in insects .
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- HY-P1882
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Peptides
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Inflammation/Immunology
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Type A Allatostatin I is a tridecapeptide. Allatostatins are pleiotropic neuropeptides for inhibition of juvenile hormone synthesis in insects .
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- HY-P3570
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Lom-AKH-II
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Endogenous Metabolite
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Metabolic Disease
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Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs) .
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- HY-P3572
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Lom-AKH-I
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Endogenous Metabolite
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Endocrinology
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Adipokinetic hormone I (Locusta migratoria) (Lom-AKH-I) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs) .
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- HY-P1183
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Peptides
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Neurological Disease
Endocrinology
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Locustatachykinin I is a insect tachykinin-related peptide isolated from Locusta migratoria. Locustatachykinin I exhibits sequence homologies with the vertebrate tachykinins. In Lacanobia, Locustatachykinin I is also a substrate for a deamidase .
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- HY-P5176
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LtTx-1a
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Peptides
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Neurological Disease
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Latartoxin-1a (LtTx-1a) is a peptide toxin can be isolated from L. tarabaevi. Latartoxin-1a is paralytic and lethal to insects and has membrane-bound activity .
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- HY-P1183A
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Peptides
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Neurological Disease
Endocrinology
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Locustatachykinin I TFA is a insect tachykinin-related peptide isolated from Locusta migratoria. Locustatachykinin I TFA exhibits sequence homologies with the vertebrate tachykinins. In Lacanobia, Locustatachykinin I TFA is also a substrate for a deamidase .
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- HY-P3825
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CCAP
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Peptides
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Cardiovascular Disease
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Crustacean cardioactive peptide (CCAP) is a insect cardioregulatory peptides that contmns 9 amino acid, first isolated from the tobacco hawkmoth, Manduca sexta. There are two cystemes at pnsttons 3 and 9 forming a disulfide bridge and the carboxyl-terminns is amldated .
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- HY-P5827
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- HY-P10034
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Pss-PT
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Peptides
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Endocrinology
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Pheromonotropin (Pseudaletia separata) (Pss-PT) is an armyworm (Pseudaletia separata) pheromone with the C-terminal pentapeptide FXPRL-amide. Pheromonotropin (Pseudaletia separata) belongs to the PK/PBAN family and stimulates sex pheromone biosynthesis in moths, mediating feeding (intestinal muscle contraction), development (embryonic diapause, pupal diapause, and pupation), and defense against natural enemy insects wait .
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- HY-P10228
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Fungal
Bacterial
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Infection
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S-Thanatin is an insect antimicrobial peptide with potent broad-spectrum antibacterial activity. S-Thanatin can inhibit the activity of Gram-negative bacteria, Gram-positive bacteria, and fungi, without cytotoxicity. The antibacterial activity of S-Thanatin is not affected by PH value, but monovalent cations (Na +/K +) can reduce its antibacterial activity against Gram-negative bacteria in a dose-dependent manner .
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- HY-P3568
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Grybi-AKH
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Peptides
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Metabolic Disease
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Adipokinetic hormone Gryllus bimaculatus (Grybi-AKH) is an adipokinetic hormone that regulates energy homeostasis in insects by mobilizing lipid and carbohydrate from the fat body. Adipokinetic hormone Gryllus bimaculatus stimulates the locomotor activity of the two-spotted cricket. Adipokinetic hormone Gryllus bimaculatus can also be used in studies to regulate body weight, induce weight loss and alleviate glycogen storage disorders in humans .
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- HY-K0220
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MCE Ni-NTA 6FF Prepacked Column is ideal for high performance purification of polyhistidine-tagged proteins expressed in E.coli, yeast, insect and mammalian expression systems.
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- HY-K0234
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1 Publications Verification
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MCE Glutathione Magnetic Agarose Beads have high protein-binding capacity and stability, making it ideal for high performance purification of GST-tagged fusion proteins expressed in E. coli, yeast, insect and mammalian expression systems.
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- HY-K1057
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5 Publications Verification
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MCE Puromycin, Sterile is an aminonucleoside antibiotic produced by Streptomyces alboniger. It inhibits protein synthesis by disrupting peptide transfer on ribosomes, causing premature chain termination during translation. It can kill most gram-positive bacteria and various animal or insect cells.
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Cat. No. |
Product Name |
Chemical Structure |
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- HY-B0978S
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Diethyltoluamide-d10 is the deuterium labeled Diethyltoluamide[1]. Diethyltoluamide is the most common active ingredient in insect repellents. It is intended to provide protection against mosquitoes, ticks, fleas, chiggers, leeches, and many other biting insects[2].
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- HY-B1946S
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Dimethoate-d6 is the deuterium labeled Dimethoate. Dimethoate is an effective systemic insecticide for use on plants, has shown promise as a chemotherapeutic agent for control of cattle grubs and certain other insect pests of farm animals, and has high contact toxicity to house-flies and many other insects[1].
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- HY-B1331S
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Cyromazine-d4 is the deuterium labeled Cyromazine. Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects.
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- HY-B0978S1
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Diethyltoluamide-d7 is the deuterium labeled Diethyltoluamide[1]. Diethyltoluamide is the most common active ingredient in insect repellents. It is intended to provide protection against mosquitoes, ticks, fleas, chiggers, leeches, and many other biting insects[2].
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- HY-B1331S1
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Cyromazine- 13C3 is the 13C3 labeled Cyromazine. Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects.
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- HY-W087988S
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3-Pentanol-d5 is the deuterium labeled 3-Pentanol[1]. 3-Pentanol is an active organic compound produced by plants and is a component of emitted insect sex pheromones. 3-pentanol elicits plant immunity against microbial pathogens and an insect pest in crop plants[2].
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- HY-B1812S
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Veratrole-d4 is the deuterium labeled Veratrole. Veratrole is an naturally occurring insect attractant .
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- HY-B1812S2
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Veratrole-d10 is the deuterium labeled Veratrole. Veratrole is an naturally occurring insect attractant .
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- HY-B1812S3
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Veratrole-d6 is the deuterium labeled Veratrole. Veratrole is an naturally occurring insect attractant .
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- HY-B1812S1
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Veratrole-d2 is the deuterium labeled Veratrole. Veratrole-d2 is an naturally occurring insect attractant .
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- HY-B0887S1
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Permethrin-d9 is the deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide, and insect repellent; functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation.
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- HY-B0827S
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Dinotefuran-d3 is the deuterium labeled Dinotefuran[1]. Dinotefuran is an insecticide of the neonicotinoid class, its mechanism of action involves disruption of the insect's nervous system by inhibiting nicotinic acetylcholine receptors[2].
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- HY-B1161S
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Methoprene-d7 is the deuterium labeled Methoprene[1]. Methoprene, an insect juvenile growth hormone mimic, is a growth-regulating insecticide that manifests its toxicity to target organisms by acting as a juvenile hormone agonist[2][3].
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- HY-B0887S
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Permethrin-d5 (NRDC-143-d5) is the deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide, and insect repellent; functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation[1][2].
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- HY-B1851S
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Hexythiazox-d11 is deuterium labeled Hexythiazox. Hexythiazox is a selective acaricide with ovicidal, larvicidal and nymphicidal activities. Hexythiazox is widely used for chemical control of mites on cotton, fruits and vegetables. Hexythiazox is harmless to mammals and has no effect on beneficial insects and predators of mites[1][2].
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- HY-B2054S
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Tebufenozide-d9 is the deuterium labeled Tebufenozide[1]. Tebufenozide is a nonsteroidal ecdysone agonist used to control pest. Tebufenozide has cytotoxic and induces apoptosis in HeLa and insect Tn5B1-4 cells[2][3].
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- HY-B1120S
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Temephos-d12 is the deuterium labeled Temephos[1]. Temefos is an organophosphate larvicide, used to treat water infested with disease-carrying insects including mosquitoes, midges, and black fly larvae. Temefos affects the central nervous system through inhibition of cholinesterase, results in death before reaching the adult stage[2][3].
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- HY-B0815S
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Chlorpyrifos-d10 is the deuterium labeled Chlorpyrifos. Chlorpyrifos is an organophosphate insecticide that is classified as a phosphorothionate. The oxon metabolite of Chlorpyrifos is an inhibitor of acetylcholinesterase (AChE), affecting neurological function in insects, humans, and other animals. The Chlorpyrifos oxon (CPO) metabolite is hydrolyzed by the plasma enzyme paraoxonase 1 (PON1), and susceptibility to neurotoxicity associated with CPO exposure is mitigated by PON1 overexpression.
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- HY-133167S
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Clothianidin-d3 is the deuterium labeled Clothianidin.Clothianidin-d3 is a neonicotinoid insecticide. Clothianidin-d3 shows excellent long-term control effect in small doses against various insect pests such as Coleoptera, Thysanoptera, Lepidoptera, Diptera, Homoptera, Heteroptera, Orthoptera and Isoptera families. Clothianidin-d3 has various application methods and high safety for crops .
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- HY-N7125S
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Cinnamyl acetate- 13C2 is 13C labeled Nerolidol (HY-N1944). Nerolidol has multiple natural membrane activities, possesses anti-cancer, anti-inflammatory, antibacterial and anti-insect activity. Nerolidol Suppresses parasitic activity, suppresses bloodsucking diseases, bloodworm diseases, and other diseases. Nerolidol can protect the cells from lipid and protein properties, damage to DNA, and protect the cells from damage .
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- HY-W017140S
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2-Sec-butyl-3-methoxypyrazine-d3 is deuterated labeled cis-?Jasmone (HY-N7058). Cis-Jasmone is a plant-derived natural product. Cis-Jasmone is constitutively released by many flowers and sometimes by leaves as an attractant for pollinators or as a chemical cue for host location by insect flower herbivores. Cis-Jasmone treatment of crop plants not only induces direct defense against herbivores, but also induces indirect defense by releasing VOCs that attract natural enemies .
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- HY-B0822S1
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Fipronil- 13C6 is the 13C-labeled Fipronil. Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 30 nM and 1,600 nM for cockroach and rat receptors, respectively). Fipronil also inhibits desensitizing and non-desensitizing glutamate-induced chloride currents in cockroach neurons (IC50s = 800 nM and 10 nM, respectively). Fipronil induces activity of the cytochrome P450 (CYP) isoforms CYP1A1/2, CYP2B1/2, and CYP3A1/2 in isolated rat liver microsomes.
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