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2’-Iodo-2’-deoxyuridine

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0307
    Idoxuridine
    3 Publications Verification

    5-Iodo-2′-deoxyuridine; 5-IUdR; IdUrd

    		 Phosphatase Orthopoxvirus Infection Cancer
    Idoxuridine (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) is an iodinated thymidine analogue that competitively inhibits phosphorylases. Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC50 value of 4.3 μM . Idoxuridine shows anti-orthopoxvirus activity.
    Idoxuridine
  • HY-W553730
    2’-Deoxy-2’-iodouridine; 2’-Iodo-2’-deoxyuridine

    		Nucleoside Antimetabolite/Analog Cancer
    2’-Deoxy-2’-iodouridine; 2’-Iodo-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    2’-<em>Deoxy</em>-2’-iodouridine; 2’-<em>Iodo-2</em>’-<em>deoxyuridine</em>
  • HY-B0307A
    Idoxuridine hydrate

    5-Iodo-2′-deoxyuridine hydrate; 5-IUdR hydrate; IdUrd hydrate

    		 Phosphatase Infection
    Idoxuridine (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) hydrate is an iodinated thymidine analogue that competitively inhibits phosphorylases. Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC50 value of 4.3 μM .
    Idoxuridine hydrate
  • HY-W397503
    5’-O-DMTr-5-iodo-2’-deoxyuridine

    2'-Deoxy-5'-O-DMT-5-Iodouridine

    		 Nucleoside Antimetabolite/Analog Cancer
    5’-O-DMTr-5-iodo-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    5’-O-DMTr-5-<em>iodo-2</em>’-<em>deoxyuridine</em>

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