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Results for "

Gd-DOTA

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

1

Fluorescent Dye

5

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-108760
    Gadoterate meglumine

    Gd-DOTA; Magnescope; P-449

    		 Biochemical Assay Reagents Cardiovascular Disease Others Neurological Disease
    Gadoterate meglumine (Gd-DOTA; P-449) is a non-specific paramagnetic gadolinium complex used as a contrast enhancer in magnetic resonance imaging (MRI). Gadoterate meglumine paramagnetics in MRI can change the uniformity of the local magnetic field, resulting in a shorter relaxation time for neighboring protons. Gadoterate meglumine's gadoterate ions combine with the ligand DOTA (1,4,7, 10-Tetraazacyclododecane-N,N',N ",N "-tetraacetic acid) to form a stable complex. This stability helps prevent gadolinium ions from dissociating from the complex, thereby reducing potential toxicity. Gadoterate meglumine, as a contrast agent in MRI, is able to shorten the longitudinal relaxation time (T1) of tissue, resulting in a brighter signal in MRI images. Gadoterate meglumine can be used for the study of the central nervous system (such as the brain and spinal cord), abdominal, pelvic organs, breast, bone and joint imaging, angiography, and cardiac electrophysiology .
    Gadoterate meglumine
  • HY-P10307
    DOTA-ubiquicidin (29–41)

    		Bacterial Infection
    DOTA-ubiquicidin (29-41), an antimicrobial peptide fragment derivative, can be used for synthesis of [ 68Ga]Ga-DOTA-Ubiquicidin29-41 and then used for imaging of infectious processes using PET/CT .
    <em>DOTA</em>-ubiquicidin (29–41)
  • HY-P10131
    3BP-3940

    		FAP Cancer
    3BP-3940 is a highly potent fibroblast activation protein (FAP)-targeting peptide for theranostics. 3BP-3940 is often coupled with radionuclides for tumor diagnosis and treatment .
    3BP-3940
  • HY-P5297
    DOTA-CXCR4-L

    		CXCR Cancer
    DOTA-CXCR4-L is a CXCR4 targeting peptide. DOTA-CXCR4-L can be used in the study of cancers, including glioblastoma and triple-negative breast cancer .
    <em>DOTA</em>-CXCR4-L
  • HY-P10444
    DOTA Conjugated JM#21 derivative 7

    		Liposome Cancer
    DOTA Conjugated JM#21 derivative 7 is a liposome to simulate biological phospholipid membrane. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble payloads can be trapped in the internal aqueous space of liposomes, while lipophilic payloads can partition into and become part of the lipid bilayer. Especially for delivering antisense oligonucleotides, it can overcome problems such as inefficient cellular uptake and rapid loss in the body .
    <em>DOTA</em> Conjugated JM#21 derivative 7
  • HY-P10273
    DOTA-Octreotide

    		Biochemical Assay Reagents Cancer
    DOTA-Octreotide is composed of chelator DOTA and Octreotide (HY-P0036). DOTA-Octreotide is utilized for diagnosis and therapy of cancer, through combination with radioactive elements .
    <em>DOTA</em>-Octreotide
  • HY-150979
    Gd-NMC-3

    		Fluorescent Dye Cancer
    Gd-NMC-3 is a near-infrared fluorescence/magnetic resonance (NIRF/MR) bimodal imaging probe. Gd-NMC-3 shows high resolution and sensitivity in tumor imaging with good biocompatibility, indicating huge application potential .
    Gd-NMC-3

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