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Results for "

Lapatinib

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

1

Peptides

5

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-50898
    Lapatinib
    Maximum Cited Publications
    63 Publications Verification

    GW572016; GW2016

    EGFR Autophagy Ferroptosis Cancer
    Lapatinib (GW572016) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .
    <em>Lapatinib</em>
  • HY-50898R

    Cancer
    Lapatinib (Standard) is the analytical standard of Lapatinib. This product is intended for research and analytical applications. Lapatinib (GW572016) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .
    <em>Lapatinib</em> (Standard)
  • HY-20390S

    Drug Metabolite Isotope-Labeled Compounds Others
    Lapatinib impurity 18-d4 is deuterium labeled 3-Chloro-4-((3-fluorobenzyl)oxy)aniline.
    <em>Lapatinib</em> impurity 18-d4
  • HY-50898S1

    GW572016-dd7 dihydrochloride; GW2016-dd7 dihydrochloride

    Isotope-Labeled Compounds EGFR Autophagy Ferroptosis Cancer
    Lapatinib-d7 (dihydrochloride) is the deuterium labeled Lapatinib dihydrochloride. Lapatinib (GW572016) dihydrochloride is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively[1].
    <em>Lapatinib</em>-d7 dihydrochloride
  • HY-50898S2

    GW572016-d5; GW2016-d5

    Isotope-Labeled Compounds EGFR Autophagy Ferroptosis Cancer
    Lapatinib-d5 is deuterium labeled Lapatinib. Lapatinib (GW572016) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively[1].
    <em>Lapatinib</em>-d5
  • HY-50898S

    GW572016-d4; GW2016-d4

    EGFR Autophagy Ferroptosis Cancer
    Lapatinib-d4 is the deuterium labeled Lapatinib (HY-50898). Lapatinib is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively[1][2].
    <em>Lapatinib</em>-d4
  • HY-50898C

    GW572016 tosylate; GW2016 tosylate

    EGFR Ferroptosis Autophagy Cancer
    Lapatinib (GW572016) tosylate is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .
    <em>Lapatinib</em> tosylate
  • HY-50898S3

    GW572016-d4-1; GW2016-d4-1

    Isotope-Labeled Compounds EGFR Autophagy Ferroptosis Cancer
    Lapatinib-d4-1 is deuterium labeled Lapatinib. Lapatinib (GW572016) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively[1].
    <em>Lapatinib</em>-d4-1
  • HY-50898A
    Lapatinib ditosylate
    Maximum Cited Publications
    63 Publications Verification

    GW572016 ditosylate; GW2016 ditosylate

    EGFR Autophagy Ferroptosis Cancer
    Lapatinib ditosylate (GW572016 ditosylate) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .
    <em>Lapatinib</em> ditosylate
  • HY-50898B
    Lapatinib ditosylate monohydrate
    Maximum Cited Publications
    63 Publications Verification

    GW572016 ditosylate monohydrate; GW2016 ditosylate monohydrate

    EGFR Autophagy Ferroptosis Cancer
    Lapatinib ditosylate monohydrate (GW572016 ditosylate monohydrate) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .
    <em>Lapatinib</em> ditosylate monohydrate
  • HY-P3498

    ZP1846

    GCGR Others
    Elsiglutide (ZP1846) is a GLP-2 analogue, an orally active and selective GLP-2 receptor agonist, increases cell proliferation and reduces apoptosis in the intestine. Elsiglutide improves Lapatinib (HY-50898)-induced diarrhoea in rat model .
    Elsiglutide
  • HY-131865

    PROTACs EGFR Others
    SJF-1521 is a selective EGFR PROTAC degrader. SJF-1521 contains the EGFR inhibitor lapatinib (HY-50898). SJF-1521 can induce EGFR degradation in OVCAR8 cells .
    SJF-1521

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