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Results for "

Mfn2

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

1

Recombinant Proteins

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W187305
    MASM7

    		Others Others
    MASM7 is a mitofusin activator, and can achieve mitochondrial fusion via mitofusins. MASM7 can increase Mito AR with an EC50 value of 75 nM in MEFs in concentration-responsively, and can promote mitochondrial fusion by directly activating MFN2 or MFN. MASM7 also demonstrates direct binding to the HR2 domain of MFN2 with Kd value of 1.1 μM .
    MASM7
  • HY-123985
    MFN2 agonist-1

    		Others Others
    MFN2 agonist-1 (B-A/l) potently stimulates mitochondrial fusion in mitofusin 2 (MFN2)-deficient cells. MFN2 agonist-1 reverses mitochondrial “clumping” (formation of static mitochondrial aggregates) and restores mitochondrial motility in cultured mouse neurons expressing the CMT2A mutant MFN2 T105M.
    <em>MFN2</em> agonist-1
  • HY-RS08384
    MFN2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others
    MFN2 Human Pre-designed siRNA Set A contains three designed siRNAs for MFN2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    MFN2 Human Pre-designed siRNA Set A
    MFN2 Human Pre-designed siRNA Set A
  • HY-13338
    Mabuterol

    		Adrenergic Receptor Cardiovascular Disease
    Mabuterol is a selective and orally active beta-2 adrenergic receptor (ADRB2) agonist. Mabuterol inhibits the proliferation and suppresses the increase of intracellular Ca2+ induced by PDGF-BB. Mabuterol suppresses the protein expressions of Drp-1, cyclinD1 and PCNA and enhanced the expression of Mfn-2 induced by PDGF-BB [2].
    Mabuterol
  • HY-W755295
    Mabuterol hydrochloride

    		Adrenergic Receptor Cardiovascular Disease
    Mabuterol hydrochloride is a selective and orally active beta-2 adrenergic receptor (ADRB2) agonist. Mabuterol hydrochloride inhibits the proliferation and suppresses the increase of intracellular Ca2+ induced by PDGF-BB. Mabuterol hydrochloride suppresses the protein expressions of Drp-1, cyclinD1 and PCNA and enhanced the expression of Mfn-2 induced by PDGF-BB [2].
    Mabuterol hydrochloride
  • HY-150031
    MFI8
    2 Publications Verification

    		 Mitochondrial Metabolism Others
    MFI8 is a small molecule inhibitor of mitochondrial .
    MFI8
  • HY-126124
    AP39
    2 Publications Verification

    		 Others Cardiovascular Disease Neurological Disease
    AP39 is a triphenylphosphonium derivatised anethole dithiolethione and mitochondria-targeting hydrogen sulfide (H2S) donor. AP39 increases intracellular H2S levels. AP39 exerts cytoprotective effects and maintains mitochondrial DNA integrity under oxidative stress conditions. AP39 protects against myocardial reperfusion injury in mice model and has the potential for Alzheimer's disease research [2] .
    AP39

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