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Results for "

RNase H

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

2

MCE Kits

2

Natural
Products

1

Recombinant Proteins

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-150759
    HIV-1 inhibitor-45

    		HIV Infection
    HIV-1 inhibitor-45 (compound IA-6) is a potent HIV-1 RNase H inhibitor with an IC50 value of 0.067 μM. HIV-1 inhibitor-45 shows an antiviral activity .
    HIV-1 inhibitor-45
  • HY-132580
    Tofersen

    BIIB067; ISIS-SOD1Rx

    		 DNA/RNA Synthesis Neurological Disease
    Tofersen (BIIB067) is an antisense oligonucleotide that mediates RNase H-dependent degradation of superoxide dismutase 1 (SOD1) mRNA to reduce the synthesis of SOD1 protein. Tofersen can be used for the research of amyotrophic lateral sclerosis (ALS) .
    Tofersen
  • HY-W028350
    NSC727447

    		HIV DNA/RNA Synthesis Infection
    NSC727447 is an inhibitor of ribonuclease H (Rnase H) of HIV-1 and HIV-2. NSC727447 has little activity against E. coli RNase H, but great selectivity over human Rnase H, with IC50s value of 2.0 μM, 2.5 μM, 100 μM, 10.6 μM, respectively .
    NSC727447
  • HY-E70098
    RNase H2

    		Others Cancer
    RNase H2 is the predominant source of RNase H activity in mammalian and human cells. RNase H2 protects genome integrity. RNase H2 has been associated with ribonucleotide removal from genomic DNA in yeast and mouse, where it is required for embryonic development .
    <em>RNase</em> <em>H</em>2
  • HY-N12387
    Laccaic acid C

    		Others Infection
    Laccaic acid C is an potent inhibitor of RNase H with an IC50 of 8.1 μM. Laccaic acid C also inhibits viral proliferation in cell .
    Laccaic acid C
  • HY-132572
    HIV-1 integrase inhibitor 9

    		HIV Infection
    HIV-1 integrase inhibitor 9 (compound 8a) is a potent HIV-1 RNase H inhibitor with an IC50 of 12.3 μM. HIV-1 integrase inhibitor 9 shows an antiviral activity .
    HIV-1 integrase inhibitor 9
  • HY-N10776
    Kaempferol-3-O-(6′′-galloyl)-β-glucopyranoside

    		HIV Infection
    Kaempferol-3-O-(6′′-galloyl)-β-glucopyranoside is a glucopyranoside. Kaempferol-3-O-(6′′-galloyl)-β-glucopyranoside inhibts HIV-2 RNase H with an IC50 value of 5.19 μM .
    Kaempferol-3-O-(6′′-galloyl)-β-glucopyranoside

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