2. Search Result
Search Result
Results for "

SIRS

" in MedChemExpress (MCE) Product Catalog:

37

Inhibitors & Agonists

26

Fluorescent Dye

2

Natural
Products

12

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D1475
    SIR-6-COOH

    		Fluorescent Dye Others
    SIR-6-COOH is a fluorescent dye. SIR-6-COOH can be used for staining proteins in live-cell STED imaging
    <em>SIR</em>-6-COOH
  • HY-157456
    RIPK1-IN-19

    		RIP kinase Inflammation/Immunology
    RIPK1-IN-19 (compound 10b) is a selective RIPK1 inhibitor (IC50=15 nM). RIPK1-IN-19 displays potent protective activity in TNFα-induced systemic inflammatory response syndrome (SIRS) model and Imiquimod (IMQ)-induced psoriasis model. RIPK1-IN-19 can be used in research on inflammation and immune system diseases .
    RIPK1-IN-19
  • HY-D2218
    SiR-alkyne

    		Fluorescent Dye Others
    SiR-alkyne is a propargyl formamide derivative of N-fluorophore silicrhodamine (SiR). SiR-alkyne reacts with azide derivatives in the presence of copper (I) to form 1, 2, 3-triazole bonds.
    <em>SiR</em>-alkyne
  • HY-D2236
    SiR-tetrazine

    		Fluorescent Dye Others
    SiR-tetrazine is a Tetrazine modified SiR (silicon rhodamine) fluorescent dye. SiR-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .
    <em>SiR</em>-tetrazine
  • HY-D2235
    SiR-Me-tetrazine

    		Fluorescent Dye Others
    SiR-Me-tetrazine is a Tetrazine modified SiR (silicon rhodamine) fluorescent dye. SiR-Me-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
    <em>SiR</em>-Me-tetrazine
  • HY-149052
    SZM-1209

    		RIP kinase Mixed Lineage Kinase Necroptosis Inflammation/Immunology
    SZM-1209 is an orally active, potent and specific RIPK1 inhibitor, with a Kd of 85 nM. SZM-1209 exhibits high anti-necroptotic activity (EC50=22.4 ± 8.1 nM). SZM-1209 shows anti-SIRS (systemic inflammatory response syndrome), and anti-ALI (acute lung injury) effects .
    SZM-1209
  • HY-D2206
    SiR650-CH2F

    		Fluorescent Dye Others
    SiR650-CH2F is a near-infrared fluorescent dye that is widely used biological imaging.Ex/Em = 600/680 nm
    <em>SiR</em>650-CH2F
  • HY-D2220
    SiR-Hoechst

    		DNA Stain Others
    SiR-Hoechst is a far-red fluorescent DNA probe being used widely for time-lapse imaging of living cells. SiR-Hoechst is minimally toxic at concentrations as high as 10-25 µM. SiR-Hoechst induces DNA damage responses and G2 arrest at concentrations well below 1 µM .
    <em>SiR</em>-Hoechst
  • HY-D2207
    SiR700-CH2F

    		Fluorescent Dye Others
    SiR700-CH2F, a near infrared silica-containing Rhodamine fluorophore, is a highly specific DNA probe (EX/Em= 680/702 nm) .
    <em>SiR</em>700-CH2F
  • HY-D2234
    SiR-PEG3-TCO

    		Fluorescent Dye Others
    SiR-PEG3-TCO is a near-infrared rhodamine fluorescent dye containing silica. SiR-PEG4-alkyne can be used in click chemistry .
    <em>SiR</em>-PEG3-TCO
  • HY-W879093
    SiR-DBCO

    		Fluorescent Dye Others
    SiR-DBCO is a fluorescent dye. SiR-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
    <em>SiR</em>-DBCO
  • HY-D2233
    SiR-PEG4-alkyne

    		Fluorescent Dye Others
    SiR-PEG4-alkyne is a near-infrared rhodamine fluorescent dye containing silica and alkynyl groups. SiR-PEG4-alkyne can be used in click chemistry .
    <em>SiR</em>-PEG4-alkyne
  • HY-100585
    Splitomicin

    Splitomycin

    		 HDAC Cancer
    Splitomicin (Splitomycin) is a selective Sir2p inhibitor. Splitomicin inhibits NAD +-dependent HDAC activity of Sir2 protein. Splitomicin induces dose-dependent inhibition of HDAC in the yeast extract with an IC50 of 60 μM .
    Splitomicin
  • HY-N2031
    Parishin

    		Others Neurological Disease
    Parishin is a phenolic glucoside isolated from Gastrodia elata. Parishin exhibits antiaging effects and extends the lifespan of yeast via regulation of Sir2/Uth1/TOR signaling pathway .
    Parishin
  • HY-D2213
    SiR-PEG4-COOH

    		Fluorescent Dye Others
    SiR-PEG4-COOH is a fluorescent dye.
    <em>SiR</em>-PEG4-COOH
  • HY-D2212
    SiR-PEG4-Maleimide

    		Fluorescent Dye Others
    SiR-PEG4-Maleimide is a fluorescent dye .
    <em>SiR</em>-PEG4-Maleimide
  • HY-D2214
    SiR-PEG4-BCN

    		Fluorescent Dye Others
    SiR-PEG4-BCN is a fluorescent dye. SiR-PEG4-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    <em>SiR</em>-PEG4-BCN
  • HY-133859
    M084

    		Mitochondrial Metabolism Metabolic Disease
    M084 is a benzimidazole derivative. M084 inhibits the mitochondrial respiration, activate mitochondrial unfolded protein response and AMPK, recruites SIR-2.1 and SKN-1, and finally through the transcription factor DAF-16, delays the aging process of C. elegans .
    M084
  • HY-W142410
    2-Dodecanol

    		Fungal Others
    2-Dodecanol inhibits hyphal formation and SIR2 expression in C. albicans .
    2-Dodecanol
  • HY-153435
    RIP1 kinase inhibitor 5

    		RIP kinase Necroptosis Cancer
    RIP1 kinase inhibitor 5 (example 1) is a potent inhibitor of RIP1, which is used as a checkpoint kinase to control tumor immunity . RIP1 kinase inhibitor 5 is similar with SIR1-365 (compound 13), which inhibits necrosis and iron death activity .
    RIP1 kinase inhibitor 5
  • HY-D2232
    SiR-PEG4-azide

    		Fluorescent Dye Others
    SiR-PEG4-azide is a near infrared silica-containing Rhodamine fluorescent dyes .
    <em>SiR</em>-PEG4-azide
  • HY-D2210
    SiR-PEG3-azide

    		Fluorescent Dye Others
    SiR-PEG3-azide is a near infrared silica-containing Rhodamine fluorescent dyes .
    <em>SiR</em>-PEG3-azide
  • HY-D2209
    SiR-PEG4-Me-tetrazine

    		Fluorescent Dye Others
    SiR-PEG4-Me-tetrazine is a small molecule click chemical modified silyl rhodamine dye.
    <em>SiR</em>-PEG4-Me-tetrazine
  • HY-D1345
    SiR-COOH

    		Fluorescent Dye Cancer
    SiR-COOH could be used to follow the intracellular location of the model therapeutic agent in GFP cells (Abs, 645 nm; Em, 676 nm) .
    <em>SiR</em>-COOH
  • HY-D1103
    SiR dye 1

    		Fluorescent Dye Others
    SiR dye 1 is a new silicon rhodamine-like fluorescent probe, and can be conjugated with small molecules, peptides and oligonucleotide aminogroups or proteins with antibodies .
    <em>SiR</em> dye 1
  • HY-D2237
    SiR-Maleimide

    		Fluorescent Dye Others
    SiR-Maleimide is a near-infrared fluorescent dye that is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling.Ex/Em = 652/674 nm
    <em>SiR</em>-Maleimide
  • HY-D2216
    SiR-azide

    		Fluorescent Dye Others
    SiR-azide is a near-infrared fluorescent dye that is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling.Ex/Em = 652/674 nm
    <em>SiR</em>-azide
  • HY-131041
    Ned-K

    		Calcium Channel Cardiovascular Disease
    Ned-K is a nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. Ned-K is effective at dampening simulated ischaemia and reperfusion (sIR)-induced Ca 2+ oscillations in cardiomyocytes .
    Ned-K
  • HY-D2211
    SiR-PEG4-NHS ester

    		Fluorescent Dye Others
    SiR-PEG4-NHS ester is a near-infrared fluorescent dye that is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling.Ex/Em = 652/674 nm
    <em>SiR</em>-PEG4-NHS ester
  • HY-15452
    Selisistat
    165+ Cited Publications

    EX-527

    		 Sirtuin Inflammation/Immunology Cancer
    Selisistat (EX-527) is a potent and selective SirT1 (Sir2 in Drosophila melanogaster) inhibitor with an IC50 of 123 nM for SirT1. Selisistat alleviates pathology in multiple animal and cell models of Huntington's disease .
    Selisistat
  • HY-N1926
    Dihydrocoumarin

    Hydrocoumarin; Chroman-2-one

    		 Sirtuin Cancer
    Dihydrocoumarin is a compound found in Melilotus officinalis. Dihydrocoumarin is a yeast Sir2p inhibitor. Dihydrocoumarin also inhibits human SIRT1 and SIRT2 with IC50s of 208 μM and 295 μM, respectively .
    Dihydrocoumarin
  • HY-D2243
    Cy3.5 tetrazine

    		Fluorescent Dye Others
    Cy3.5 tetrazineis a Tetrazine modified Cy3.5 fluorescent dye. SiR-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .
    Cy3.5 tetrazine
  • HY-163390
    RIP1 kinase inhibitor 9

    		RIP kinase Necroptosis Inflammation/Immunology Cancer
    RIP1 kinase inhibitor 9 (compound SY-1) is a selective RIP kinase inhibitor. RIP1 kinase inhibitor 9 effectively suppresses the central inflammatory response induced by epilepsy. RIP1 kinase inhibitor 9 inhibits Z-VAD-FMK (HY-16658B)-induced necroptosis in HT-29 cells with an EC50 of 7.04 nM .
    RIP1 kinase inhibitor 9
  • HY-D1104
    SiR dye 2

    		Fluorescent Dye Others
    SiR dye 2 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    <em>SiR</em> dye 2
  • HY-D1380
    SiR-NHS

    		Fluorescent Dye Others
    SiR-NHS is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    <em>SiR</em>-NHS
  • HY-D1679
    Phalloidin-f-HM-SiR

    		Fluorescent Dye Others
    Phalloidin-f-HM-SiR is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    Phalloidin-f-HM-<em>SiR</em>
  • HY-D1105
    SiR dye 3

    		Fluorescent Dye Others
    SiR dye 3 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    <em>SiR</em> dye 3

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: