Search Result
Results for "
amyloid β-peptides
" in MedChemExpress (MCE) Product Catalog:
1
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-P0128
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amyloid beta-peptide (25-35); Aβ25-35; β-amyloid peptide (25-35)
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Amyloid-β
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Neurological Disease
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β-Amyloid (25-35) (Amyloid beta-peptide (25-35)) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide, has shown neurotoxic activities in cultured cells .
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- HY-P1522
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- HY-P4882
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Amyloid-β
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Neurological Disease
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(Pyr3)-Amyloid β-Protein (3-42) is the predominant amyloid β-peptide structure deposited in human brain of Alzheimer's disease and Down's syndrome patients. (Pyr3)-Amyloid β-Protein (3-42) is suggested to accumulate in the brain and to trigger the formation of insoluble amyloid β-peptide deposits .
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- HY-P4882A
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Amyloid-β
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Neurological Disease
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(Pyr3)-Amyloid β-Protein (3-42) TFA is the predominant amyloid β-peptide structure deposited in human brain of Alzheimer's disease and Down's syndrome patients. (Pyr3)-Amyloid β-Protein (3-42) TFA is suggested to accumulate in the brain and to trigger the formation of insoluble amyloid β-peptide deposits .
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- HY-P1510
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- HY-P1517
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- HY-P1521
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Beta-amyloid (15-21)
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Amyloid-β
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Neurological Disease
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β-amyloid (15-21) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.
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- HY-P1524
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- HY-P1053
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- HY-17631A
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- HY-P1567
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Amyloid-β
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Neurological Disease
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β-Amyloid (10-35), amide is composed of 26 aa (10-35 residues of the Aβ peptide) and is the primary component of the amyloid plaques of Alzheimer’s disease.
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- HY-P2562
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Amyloid-β
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Neurological Disease
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β-Amyloid (1-38), mouse, rat is composed of 38 aa (1-38 residues of the Aβ peptide) and is the primary component of the amyloid plaques of Alzheimer’s disease .
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- HY-P1362
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amyloid β Peptide (42-1)(human)
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Amyloid-β
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Neurological Disease
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β-Amyloid (42-1), human is the inactive form of Amyloid β Peptide (1-42). β-Amyloid (42-1), human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease .
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- HY-P1362A
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amyloid β Peptide (42-1)(human) TFA
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Amyloid-β
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Neurological Disease
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β-Amyloid (42-1), human TFA is the inactive form of Amyloid β Peptide (1-42). β-Amyloid (42-1), human TFA is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease .
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- HY-P1363A
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amyloid β-peptide (1-42) (human)
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Amyloid-β
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Neurological Disease
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β-Amyloid (1-42), human (Amyloid β-peptide (1-42), human) is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease .
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- HY-P1363F3
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5-FAM-amyloid β-peptide (1-42) (human) Tris
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Amyloid-β
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Others
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5-FAM-β-Amyloid (1-42), human (5-FAM-Amyloid β-peptide (1-42) (human) TFA is a5-FAM labeled β-Amyloid (1-42), human TFA (HY-P1363).
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- HY-100200
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SMER28
1 Publications Verification
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Autophagy
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Cancer
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SMER28 is a positive regulator of autophagy acting via an mTOR-independent mechanism. SMER28 prevents the accumulation of amyloid beta peptide.
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- HY-P1363
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β-amyloid (1-42), human TFA; amyloid β-peptide (1-42) (human) TFA
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Amyloid-β
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Neurological Disease
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β-Amyloid (1-42), human TFA (Amyloid β-Peptide (1-42) (human) TFA) is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease .
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- HY-P1962
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[Asn670, Sta671, Val672]-amyloid β Peptide (662-675)
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Beta-secretase
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Neurological Disease
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β-Secretase inhibitor ([Asn670, Sta671, Val672]-Amyloid β Peptide (662-675)) is a β-secretase and BACE1 inhibitor (IC50: 25 nM for β-secretase) .
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- HY-W010041
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Amyloid-β
Endogenous Metabolite
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Neurological Disease
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Scyllo-Inositol, an amyloid inhibitor, potentialy inhibits α-synuclein aggregation. Scyllo-Inositol stabilizes a non-fibrillar non-toxic form of amyloid-β peptide (Aβ42) in vitro, reverses cognitive deficits, and reduces synaptic toxicity and lowers amyloid plaques in an Alzheimer's disease mouse model .
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- HY-P1363S
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amyloid β-peptide-15N (1-42) (human) TFA
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Amyloid-β
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Neurological Disease
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β-Amyloid- 15N (1-42), human (TFA) is the 15N-labledβ-Amyloid (1-42) (TFA). β-Amyloid (1-42), human TFA (Amyloid β-Peptide (1-42) (human) TFA) is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease[1].
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- HY-103538
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Amyloid-β
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Neurological Disease
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JLK-6 markedly reduce the production of amyloid β-peptide (Aβ) by amyloid-β Precursor protein (APP) expressing HEK293 cells by affecting the γ-secretase cleavage of APP, with no effect on the cleavage of the Notch receptor .
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- HY-P3275
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Aβ(17-40)
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Amyloid-β
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Neurological Disease
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β-Amyloid (17-40) (Aβ(17-40)) is a fragment of Amyloid-β peptide that has shown neurotoxic activities in SH-SY5Y and IMR-32 cells. β-Amyloid (17-40) can be used for the research of neurological disease .
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- HY-P1363F1
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Biotin-amyloid β-peptide (1-42) (human) TFA
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Amyloid-β
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Neurological Disease
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Biotin-β-Amyloid (1-42), human TFA (Biotin-Amyloid β-Peptide (1-42) (human) TFA) is the botin labeled β-Amyloid (1-42), human TFA (HY-P1363). β-Amyloid (1-42), human TFA is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease .
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- HY-P99317
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Immunoglobulin G1, anti-(human β-amyloid) (human-mouse monoclonAnti-Human Abeta Recombinant Antibody
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Amyloid-β
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Neurological Disease
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Solanezumab is a humanized monoclonal IgG1 antibody directed against the mid-domain of the amyloid-β (Aβ) peptide. Solanezumab has the potential for the research of Alzheimer’s disease .
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- HY-163441
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Cholinesterase (ChE)
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Neurological Disease
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BChE-IN-31 (Compound 14d) is a selective BChE inhibitor with an IC50 of 65 nM. BChE-IN-31 inhibits the self-induced aggregation of neurotoxic amyloid-β (Aβ) peptide .
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- HY-P1387
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Amyloid-β
Apoptosis
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Neurological Disease
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β-Amyloid (1-40) (rat) is a rat form of the amyloid β-peptide, which accumulates as an insoluble extracellular deposit around neurons, giving rise to the senile plaques associated with Alzheimer's disease (AD). β-Amyloid (1-40) (rat) increases 45Ca 2+ influx, induces neurodegeneration in the rat hippocampal neurons of the CA1 subfield. β-Amyloid (1-40) (rat) induces apoptosis. β-Amyloid (1-40) (rat) can be used for the research of Alzheimer's disease .
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- HY-N2319
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DHEC mesylate
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Amyloid-β
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Neurological Disease
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Dihydroergocristine mesylate (DHEC mesylate) is a inhibitor of γ-secretase (GSI), reduces the production of the Alzheimer's disease amyloid-β peptides, binds directly to γ-secretase and Nicastrin with equilibrium dissociation constants (Kd) of 25.7 nM and 9.8 μM, respectively .
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- HY-157296
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Cholinesterase (ChE)
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Neurological Disease
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AChE-IN-47 (compound g17) is a AChE inhibitor with the IC50 of 0.24 μM. AChE-IN-47 inhibits amyloid β peptides self-aggregation. AChE-IN-47 displays neuroprotective effects and effectively suppresses the intracellular accumulation of reactive oxygen species .
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- HY-150049
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Amyloid-β
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Neurological Disease
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γ-Secretase modulator 13 (compound 4) is a gamma-secretase modulator (GSMs) that inhibits the production of the aggregated amyloid β-peptide Aβ42 with an IC50 value of 163 nM. γ-Secretase modulator 13 can be used in the study of Alzheimer's disease .
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- HY-150050
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Amyloid-β
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Neurological Disease
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gamma-secretase modulator 5 (compound 22d) is a brain-penetrant gamma-secretase modulator (GSMs) that inhibits the production of the aggregated amyloid β-peptide Aβ42 with an IC50 value of 60 nM. gamma-secretase modulator 5 can be used in the study of Alzheimer's disease .
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- HY-N2319R
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DHEC mesylate (Standard)
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Amyloid-β
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Neurological Disease
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Dihydroergocristine (mesylate) (Standard) is the analytical standard of Dihydroergocristine (mesylate). This product is intended for research and analytical applications. Dihydroergocristine mesylate (DHEC mesylate) is a inhibitor of γ-secretase (GSI), reduces the production of the Alzheimer's disease amyloid-β peptides, binds directly to γ-secretase and Nicastrin with equilibrium dissociation constants (Kd) of 25.7 nM and 9.8 μM, respectively .
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- HY-N0061
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Reactive Oxygen Species
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Neurological Disease
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Ethyl ferulate, a naturally lipophilic derivative of ferulic acid originally derived from Rhizoma Chuanxiong, induces heme oxygenase-1 (HO-1) and protects rat neurons against oxidative stress . Ethyl ferulate also protects neurons against amyloid β peptide (1-42)-induced oxidative stress and neurotoxicity .
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- HY-112636
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Amyloid-β
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Others
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Astrophloxine is a fluorescent imaging probe capable of targeting antiparallel dimers. Astrophloxine can be used to detect aggregated Aβ in brain tissue and cerebrospinal fluid samples of Alzheimer's disease (AD) mice .
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- HY-N8161
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Kaempferol 3,7-diglucoside
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Glucosidase
Cholinesterase (ChE)
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Neurological Disease
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Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside), a flavonol, possesses enzyme inhibition property towards α-amylase, α-glucosidase and Acetylcholinesterase. Kaempferol-3,7-di-O-β-glucoside protects differentiating neuronal cells, SH-SY5Y from Amyloid β peptide-induced injury. Kaempferol-3,7-di-O-β-glucoside has the potential for Alzheimer's research .
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Cat. No. |
Product Name |
Type |
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- HY-P1363F3
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5-FAM-amyloid β-peptide (1-42) (human) Tris
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Fluorescent Dyes/Probes
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5-FAM-β-Amyloid (1-42), human (5-FAM-Amyloid β-peptide (1-42) (human) TFA is a5-FAM labeled β-Amyloid (1-42), human TFA (HY-P1363).
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Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P0128
-
amyloid beta-peptide (25-35); Aβ25-35; β-amyloid peptide (25-35)
|
Amyloid-β
|
Neurological Disease
|
β-Amyloid (25-35) (Amyloid beta-peptide (25-35)) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide, has shown neurotoxic activities in cultured cells .
|
-
- HY-P1522
-
-
- HY-P4882
-
|
Amyloid-β
|
Neurological Disease
|
(Pyr3)-Amyloid β-Protein (3-42) is the predominant amyloid β-peptide structure deposited in human brain of Alzheimer's disease and Down's syndrome patients. (Pyr3)-Amyloid β-Protein (3-42) is suggested to accumulate in the brain and to trigger the formation of insoluble amyloid β-peptide deposits .
|
-
- HY-P4882A
-
|
Amyloid-β
|
Neurological Disease
|
(Pyr3)-Amyloid β-Protein (3-42) TFA is the predominant amyloid β-peptide structure deposited in human brain of Alzheimer's disease and Down's syndrome patients. (Pyr3)-Amyloid β-Protein (3-42) TFA is suggested to accumulate in the brain and to trigger the formation of insoluble amyloid β-peptide deposits .
|
-
- HY-P1510
-
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- HY-P1517
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-
- HY-P1521
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Beta-amyloid (15-21)
|
Amyloid-β
|
Neurological Disease
|
β-amyloid (15-21) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.
|
-
- HY-P1524
-
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- HY-P1053
-
-
- HY-P1567
-
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Amyloid-β
|
Neurological Disease
|
β-Amyloid (10-35), amide is composed of 26 aa (10-35 residues of the Aβ peptide) and is the primary component of the amyloid plaques of Alzheimer’s disease.
|
-
- HY-P2562
-
|
Amyloid-β
|
Neurological Disease
|
β-Amyloid (1-38), mouse, rat is composed of 38 aa (1-38 residues of the Aβ peptide) and is the primary component of the amyloid plaques of Alzheimer’s disease .
|
-
- HY-P1362
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amyloid β Peptide (42-1)(human)
|
Amyloid-β
|
Neurological Disease
|
β-Amyloid (42-1), human is the inactive form of Amyloid β Peptide (1-42). β-Amyloid (42-1), human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease .
|
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- HY-P1362A
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amyloid β Peptide (42-1)(human) TFA
|
Amyloid-β
|
Neurological Disease
|
β-Amyloid (42-1), human TFA is the inactive form of Amyloid β Peptide (1-42). β-Amyloid (42-1), human TFA is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease .
|
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- HY-P1363A
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amyloid β-peptide (1-42) (human)
|
Amyloid-β
|
Neurological Disease
|
β-Amyloid (1-42), human (Amyloid β-peptide (1-42), human) is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease .
|
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- HY-P1363F3
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5-FAM-amyloid β-peptide (1-42) (human) Tris
|
Amyloid-β
|
Others
|
5-FAM-β-Amyloid (1-42), human (5-FAM-Amyloid β-peptide (1-42) (human) TFA is a5-FAM labeled β-Amyloid (1-42), human TFA (HY-P1363).
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- HY-P1363
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β-amyloid (1-42), human TFA; amyloid β-peptide (1-42) (human) TFA
|
Amyloid-β
|
Neurological Disease
|
β-Amyloid (1-42), human TFA (Amyloid β-Peptide (1-42) (human) TFA) is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease .
|
-
- HY-P1962
-
[Asn670, Sta671, Val672]-amyloid β Peptide (662-675)
|
Beta-secretase
|
Neurological Disease
|
β-Secretase inhibitor ([Asn670, Sta671, Val672]-Amyloid β Peptide (662-675)) is a β-secretase and BACE1 inhibitor (IC50: 25 nM for β-secretase) .
|
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- HY-P1363S
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amyloid β-peptide-15N (1-42) (human) TFA
|
Amyloid-β
|
Neurological Disease
|
β-Amyloid- 15N (1-42), human (TFA) is the 15N-labledβ-Amyloid (1-42) (TFA). β-Amyloid (1-42), human TFA (Amyloid β-Peptide (1-42) (human) TFA) is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease[1].
|
-
- HY-P3275
-
Aβ(17-40)
|
Amyloid-β
|
Neurological Disease
|
β-Amyloid (17-40) (Aβ(17-40)) is a fragment of Amyloid-β peptide that has shown neurotoxic activities in SH-SY5Y and IMR-32 cells. β-Amyloid (17-40) can be used for the research of neurological disease .
|
-
- HY-P1363F1
-
Biotin-amyloid β-peptide (1-42) (human) TFA
|
Amyloid-β
|
Neurological Disease
|
Biotin-β-Amyloid (1-42), human TFA (Biotin-Amyloid β-Peptide (1-42) (human) TFA) is the botin labeled β-Amyloid (1-42), human TFA (HY-P1363). β-Amyloid (1-42), human TFA is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease .
|
-
- HY-P1387
-
|
Amyloid-β
Apoptosis
|
Neurological Disease
|
β-Amyloid (1-40) (rat) is a rat form of the amyloid β-peptide, which accumulates as an insoluble extracellular deposit around neurons, giving rise to the senile plaques associated with Alzheimer's disease (AD). β-Amyloid (1-40) (rat) increases 45Ca 2+ influx, induces neurodegeneration in the rat hippocampal neurons of the CA1 subfield. β-Amyloid (1-40) (rat) induces apoptosis. β-Amyloid (1-40) (rat) can be used for the research of Alzheimer's disease .
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P99317
-
Immunoglobulin G1, anti-(human β-amyloid) (human-mouse monoclonAnti-Human Abeta Recombinant Antibody
|
Amyloid-β
|
Neurological Disease
|
Solanezumab is a humanized monoclonal IgG1 antibody directed against the mid-domain of the amyloid-β (Aβ) peptide. Solanezumab has the potential for the research of Alzheimer’s disease .
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
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- HY-P1363S
-
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β-Amyloid- 15N (1-42), human (TFA) is the 15N-labledβ-Amyloid (1-42) (TFA). β-Amyloid (1-42), human TFA (Amyloid β-Peptide (1-42) (human) TFA) is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease[1].
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