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Results for "

chemoprevention

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

3

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-107377
    Benzo[a]pyrene
    3 Publications Verification

    3,4-Benzopyrene

    		 Endogenous Metabolite Cancer
    Benzo[a]pyrene shows lung carcinogenicity in animal models, and it is frequently used in chemoprevention studies.
    Benzo[a]pyrene
  • HY-107377S
    Benzo[a]pyrene-d12

    		Endogenous Metabolite Cancer
    Benzo[a]pyrene-d12 is the deuterium labeled Benzo[a]pyrene[1]. Benzo[a]pyrene shows lung carcinogenicity in animal models, and it is frequently used in chemoprevention studies[2][3].
    Benzo[a]pyrene-d12
  • HY-126379
    CDDO-2P-Im

    		Apoptosis Cancer
    CDDO-2P-Im is an analogue of CDDO-Imidazolide with chemopreventive effect. CDDO-2P-Im can reduce the size and the severity of the lung tumors in mouse lung cancer model .
    CDDO-2P-Im
  • HY-135953
    CDDO-3P-Im

    		Apoptosis Cancer
    CDDO-3P-Im is an analogue of CDDO-Imidazolide with chemopreventive effect. CDDO-3P-Im can reduce the size and the severity of the lung tumors in mouse lung cancer model . CDDO-3P-Im is a orally active necroptosis inhibitor that can be used for the research of ischemia/reperfusion (I/R) .
    CDDO-3P-Im
  • HY-N0560
    Oroxylin A
    Maximum Cited Publications
    7 Publications Verification

    Baicalein 6-methyl ether; 6-Methoxybaicalein

    		 HIF/HIF Prolyl-Hydroxylase Autophagy Virus Protease Cancer
    Oroxylin A is an active flavonoid compound with strong anti-cancer effects. Oroxylin A inhibits the IL-6/STAT3 pathway and NF-κB signaling, inhibits cell proliferation and induces apoptosis. Oroxylin A inhibits colitis-related carcinogenesis .
    Oroxylin A
  • HY-N2149A
    Tomatidine hydrochloride
    5 Publications Verification

    		 NF-κB JNK Autophagy Endogenous Metabolite Cardiovascular Disease Inflammation/Immunology
    Tomatidine hydrochloride acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling . Tomatidine hydrochloride activates autophagy either in mammal cells or C elegans .
    Tomatidine hydrochloride
  • HY-115866
    COX-2-IN-6

    		COX Cancer
    COX-2-IN-6 (compound 10) is an orally active, gut-restricted and selective cyclooxygenase-2 (COX-2) inhibitor for colorectal Chemoprevention of cancer. COX-2-IN-6 selectively targets COX-2 with an IC50 of 0.84 μM and a Ki of 69 nM. COX-2-IN-6 also inhibits COX-2-driven PGE2 synthesis with an IC50 of 0.60 μM .
    COX-2-IN-6

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