chloride

By Targets:	Chloride Channel (9) Bacterial (1) Biochemical Assay Reagents (3) COX (1) Fluorescent Dye (1) GABA Receptor (2) GlyT (1) Isotope-Labeled Compounds (1) Neurokinin Receptor (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (1) Infection (2) Inflammation/Immunology (4) Metabolic Disease (2) Neurological Disease (2)

Targets Recommended: Chloride Channel

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-101014

Octanoylcarnitine chloride	Biochemical Assay Reagents	Infection
Octanoylcarnitine chloride is a homolog of acetylcarnitine chloride. Octanoylcarnitine chloride can enhance absorption of drugs from gastrointestinal tract .

HY-69359

Nipecotic acid (±)-β-Homoproline; Hexahydronicotinic acid; 3-Carboxypiperidine	GABA Receptor	Neurological Disease
Nipecotic acid ((±)-β-Homoproline) is a potent inhibitor of neuronal and glial-aminobutyric acid (GABA) uptake in vitro. Nipecotic acid can also directly activate GABA_A-like chloride channels, with an EC₅₀ of approximately 300 μM .

HY-W687022A

Chloroethene (polymer) Polyvinyl chloride	Biochemical Assay Reagents	Others
Chloroethene (Polyvinyl chloride) polymer is a chemical reagent. Chloroethene polymer is a polymer form of Chloroethene. Chloroethene polymer is used in a very wide range of areas, such as interior surfaces, food wrappers, and covering of crops in agriculture .

HY-B0493

Niflumic acid 1 Publications Verification	Chloride Channel COX	Inflammation/Immunology
Niflumic acid is a calcium-activated chloride channel blocker and COX-2 inhibitor with the IC₅₀ value of 100 nM. Niflumic acid induces apoptosis through caspase-8/Bid/Bax pathway in lung cancer cells. Niflumic acide exhibits anti-tumor activity by affecting the expression of ERK1/2 and the activity of MMP2 and MMP9. Niflumic acid has orally bioactivity. Niflumic acid acts on rheumatoid arthritis .

HY-D0133

NBD-X acid	Fluorescent Dye	Others
NBD-X acid is a fluorescent probe for the study of fatty acids and sterols. NBD-X acid provides better yields for labelling biopolymers compared to NBD chloride and fluoride. The fluorescence spectrum of the NBD derivative is highly sensitive to the environment and the fluorescence intensity is significantly reduced in aqueous solutions .

HY-N1462

Atractyloside potassium salt 2 Publications Verification	Chloride Channel	Cardiovascular Disease
Atractyloside potassium salt is a toxic diterpenoid glycoside that can be isolated from the fruits of Xanthium sibiricum. Atractyloside potassium salt is a powerful and specific inhibitor of mitochondrial ADP/ATP transport. Atractyloside potassium salt inhibits chloride channels from mitochondrial membranes of rat heart .

HY-B1494

Picrotoxinin 3 Publications Verification	Chloride Channel GABA Receptor	Neurological Disease
Picrotoxinin, a potent convulsant, is a chloride channel blocker. Picrotoxinin is a noncompetitive GABA_A receptor antagonist, which negatively modulates the action of GABA on GABA_A receptors. Picrotoxinin inhibits α₁β₂γ_2L GABA_A receptor with an IC₅₀ of 1.15 μM .

HY-W009823

Phenyl benzoate	Chloride Channel	Others
Phenyl benzoate is a benzoate ester obtained by the formal condensation of phenol with benzoic acid. Phenyl benzoate is a chloride transport blocker, inhibits Cl ^--dependent Glu accumulation into vesicles. Phenyl benzoate can be used as preservative in cosmetic products .

HY-101329

Anthracene-9-carboxylic acid 9-Anthracenecarboxylic acid	Chloride Channel	Others
Anthracene-9-carboxylic acid (9-Anthracenecarboxylic acid) is an anthracene derivative traditionally used to block and identify Ca ²⁺-activated Cl ^- currents (CaCCs) in various cell types, like diverse smooth muscle cells, epithelial cells and salivary gland cells .

HY-129140

Delphinidin-3-O-arabinoside chloride	Others	Others
Delphinidin-3-O-arabinoside chloride is an anthocyanin chloride compound. It is formed by combining Delphinidin (an anthocyanin with a natural purple color) with the 3-O-arabinoside group. Delphinidin-3-O-arabinoside can be isolated from Rhododendron and is in the form of furanose .

HY-157203

Cholic acid-cysteine-cyanuric chloride complex	Others	Others
Cholic acid-cysteine-cyanuric chloride complex is a hapten linker molecule comprising of the antigen, cholic acid and the reactive group for covalent attachment, cyanuric chloride .

HY-142104

2-CTC Resin	Others	Cancer
2-CTC Resin is an alkaline protein that has been used to study metabolic disorders in prostate cancer cells. It can be used as a reaction solution of terminal residues and adenine nucleotides to form cyclic peptides. 2-CTC Resin is one of the most commonly used and versatile resins available for large-scale production of peptides .

HY-113202S1

Stearoyl-L-carnitine-d9 chloride	Isotope-Labeled Compounds GlyT	Metabolic Disease
Stearoyl-L-carnitine-d9 chloride is the deuterium labeled Stearoyl-L-carnitine chloride. Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2 .

HY-146320

ANO1-IN-1	Chloride Channel	Cancer
ANO1-IN-1 (Compound 9c) is a selective ANO1 channel blocker with an IC₅₀ of 2.56 μM and 15.43 μM against ANO1 and ANO2, respectively. ANO1-IN-1 suppresses strongly proliferation of glioblastoma cells .

HY-146321

ANO1-IN-2	Chloride Channel	Cancer
ANO1-IN-2 (Compound 10q) is a selective ANO1 channel blocker with an IC₅₀ of 1.75 μM and 7.43 μM against ANO1 and ANO2, respectively. ANO1-IN-2 suppresses strongly proliferation of glioblastoma cells .

HY-B2227C

Lactate potassium Lactic acid potassium	Bacterial	Infection Others
Lactate (Lactic acid) potassium is used as a sodium chloride substitute in the elaboration of dry meat products. Lactate potassium (56%) and sodium diacetate (4%) mixture inhibit the development of L. sake and L. monocytogenes bacteria at 4℃ to extend the shelf life of food .

HY-109542

Cyclopenthiazide	Others	Metabolic Disease
Cyclopenthiazide is a benzothiadiazine diuretic with antihypertensive properties. Cyclopenthiazide exerts a diuretic effect by inhibiting the reabsorption of sodium chloride and water at the distal renal tubules. Cyclopenthiazide increases the excretory capacity of the rat kidney .

HY-B2078A

Eprazinone dihydrochloride	Neurokinin Receptor	Inflammation/Immunology
Eprazinone dihydrochloride is a gent with mucolytic, secretolytic, antitussive, and bronchial antispasmodic properties. Eprazinone dihydrochloride is a neurokinin 1 receptor (NK1R) ligand. Eprazinone dihydrochloride has the potential for chronic bronchitis treatment that improved pulmonary function and arterial partial pressure of oxygen .

HY-118170

T16A(inh)-C01	Chloride Channel	Others
T16A(inh)-C01 is an inhibitor of TMEM16A (ANO1). T16A(inh)-C01 blocks chloride channel mediated by ANO1 with an IC₅₀ of 8.4 μM, without interfering with calcium signaling .

HY-W040265

Fenamic acid N-Phenylanthranilic acid	Chloride Channel	Inflammation/Immunology
Fenamic acid (N-Phenylanthranilic acid, NPAA) is an orally active chloride channel blocker. Fenamic acid is the basic constituent of non-steroidal anti-inflammatory agents (NSAIA), and derives into mefenamic, tofenacin, flufenac acid and melofenac acid. Fenamic acid also acts as antibacterial and analgesic agent ^- .

HY-D0876

POPSO	Biochemical Assay Reagents	Others
POPSO is a zwitterionic buffer, increases osmolality and shows marked inhibition of anion uniport. POPSO inhibits chloride uniport with an IC₅₀ value of 24 mM. POPSO enhances copper uptake and toxicity in alga, impairs mitochondrial inner membrane. The working pH range of POPSO sesquisodium salt is 7.2-8.5 .

Cat. No.	Product Name	Type

HY-D0133

NBD-X acid	Fluorescent Dyes/Probes
NBD-X acid is a fluorescent probe for the study of fatty acids and sterols. NBD-X acid provides better yields for labelling biopolymers compared to NBD chloride and fluoride. The fluorescence spectrum of the NBD derivative is highly sensitive to the environment and the fluorescence intensity is significantly reduced in aqueous solutions .

Cat. No.	Product Name	Type

HY-D0876

POPSO	Biochemical Assay Reagents
POPSO is a zwitterionic buffer, increases osmolality and shows marked inhibition of anion uniport. POPSO inhibits chloride uniport with an IC₅₀ value of 24 mM. POPSO enhances copper uptake and toxicity in alga, impairs mitochondrial inner membrane. The working pH range of POPSO sesquisodium salt is 7.2-8.5 .

HY-Y0537E

Potassium chloride, for cell culture	Buffer Reagents
Potassium chloride, for cell culture is a form of potassium chloride that can be used at the cellular level and can be used as a potassium supplement.

HY-Y0537B

Potassium chloride, for molecular biology	Buffer Reagents
Potassium chloride, for molecular biology is a potassium chloride that can be used at the molecular level for protein extraction and solubilization.

HY-Y0344H

Sodium chloride, United States Pharmacopeia (USP) Reference Standard Halite (Pharmaceutical primary standard, USP)	Buffer Reagents
Sodium chloride, United States Pharmacopeia (USP) Reference Standard is an inorganic salt that can be used for life science related research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N1462

Atractyloside potassium salt 2 Publications Verification	Cardiovascular Disease Structural Classification Classification of Application Fields Terpenoids Pterocarpus soyauxii Taub. Source classification Diterpenoids Plants Compositae Disease Research Fields	Chloride Channel
Atractyloside potassium salt is a toxic diterpenoid glycoside that can be isolated from the fruits of Xanthium sibiricum. Atractyloside potassium salt is a powerful and specific inhibitor of mitochondrial ADP/ATP transport. Atractyloside potassium salt inhibits chloride channels from mitochondrial membranes of rat heart .

HY-B1494

Picrotoxinin 3 Publications Verification	Structural Classification Natural Products other families Source classification Plants	Chloride Channel GABA Receptor
Picrotoxinin, a potent convulsant, is a chloride channel blocker. Picrotoxinin is a noncompetitive GABA_A receptor antagonist, which negatively modulates the action of GABA on GABA_A receptors. Picrotoxinin inhibits α₁β₂γ_2L GABA_A receptor with an IC₅₀ of 1.15 μM .

HY-129140

Delphinidin-3-O-arabinoside chloride	Structural Classification Anthocyans Flavonoids Rhododendron simsii Planch. Source classification Plants Ericaceae	Others
Delphinidin-3-O-arabinoside chloride is an anthocyanin chloride compound. It is formed by combining Delphinidin (an anthocyanin with a natural purple color) with the 3-O-arabinoside group. Delphinidin-3-O-arabinoside can be isolated from Rhododendron and is in the form of furanose .

Cat. No.	Product Name	Chemical Structure

HY-113202S1

Stearoyl-L-carnitine-d9 chloride
Stearoyl-L-carnitine-d9 chloride is the deuterium labeled Stearoyl-L-carnitine chloride. Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2 .

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