derivatization

By Targets:	ADC Linker (2) Amino Acid Derivatives (1) Bcl-2 Family (1) Biochemical Assay Reagents (6) Drug Metabolite (1) Fluorescent Dye (6) HIV (1) Insulin Receptor (2)
By Research Areas:	Cancer (3) Endocrinology (2) Infection (1) Metabolic Disease (3)
Click Chemistry:	Labeling and Fluorescence Imaging (2) TCO (2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-136590

2-Nitrosopyridine 1 Publications Verification	Others	Others
2-Nitrosopyridine is a nitroso compound that can be used to synthesize antibiotics. 2-Nitrosopyridine can be used as a Click or Diels-Alder derivatization reagent and an excellent dienophile .

HY-W320397

4-(2-Aminoethylamino)-7-(N,N-dimethylsulfamoyl)benzofurazan	Fluorescent Dye	Others
4-(2-Aminoethylamino)-7-(N,N-dimethylsulfamoyl)benzofurazan is a precolumn fluorescence derivatization reagent.

HY-D0035

MPAC-Br

Fluorescent Dye Others

MPAC-Br is a highly sensitive fluorescent derivatization reagent for carboxylic acids in HPLC .

MPAC-Br	Fluorescent Dye	Others
MPAC-Br is a highly sensitive fluorescent derivatization reagent for carboxylic acids in HPLC .

HY-147232

N-Acryloyl-1-pyrenebutylamine	Fluorescent Dye	Others
N-Acryloyl-1-pyrenebutylamine is a potent fluorescent derivatization agent. N-Acryloyl-1-pyrenebutylamine combines with an alkyl-acrylamide side-chain to give fluorescence function on the polymer. .

HY-118469

Phanquinone 11925 C; Entronon	Others	Others
Phanquone (11925 C; Entronon) derives from a hydride of a 4,7-phenanthroline. Phanquone is applied as an original precolumn derivatization reagent for amino acids .

HY-138064

4-APC hydrobromide	Others	Others
4-APC hydrobromide is a highly sensitive and selective derivatization agent for aldehydes. 4-APC hydrobromide possesses an aniline moiety for a fast selective reaction with aliphatic aldehydes as well as a quaternary ammonium group for improved MS sensitivity. 4-APC hydrobromide allows highly sensitive and selective MS detection of aldehydes .

HY-131125

trans-4-Nitrocinnamoyl chloride

Biochemical Assay Reagents Others

trans-4-Nitrocinnamoyl chloride is used as derivatization reagent .
HY-156559

GlcNAc-SH

Biochemical Assay Reagents Others

GlcNAc-SH is a thiol-derivatized saccharide that can be used to label Dha to generate glycoprotein mimics .
HY-W014815

BPBA

2-Bromopyridine-5-boronic acid
Biochemical Assay Reagents Others

BPBA (2-Bromopyridine-5-boronic acid) is a new labeling reagent to derivatize brassinosteroids (BRs) .
HY-N12840

Logmalicid B

Others Metabolic Disease

Logmalicid B is an iridoid glycoside compound that can be isolated from Cornus officinalis and can be used in diabetes research .

trans-4-Nitrocinnamoyl chloride	Biochemical Assay Reagents	Others
trans-4-Nitrocinnamoyl chloride is used as derivatization reagent .

GlcNAc-SH	Biochemical Assay Reagents	Others
GlcNAc-SH is a thiol-derivatized saccharide that can be used to label Dha to generate glycoprotein mimics .

BPBA 2-Bromopyridine-5-boronic acid	Biochemical Assay Reagents	Others
BPBA (2-Bromopyridine-5-boronic acid) is a new labeling reagent to derivatize brassinosteroids (BRs) .

Logmalicid B	Others	Metabolic Disease
Logmalicid B is an iridoid glycoside compound that can be isolated from Cornus officinalis and can be used in diabetes research .

HY-101890

Dabsyl chloride 2 Publications Verification DABS-Cl	Fluorescent Dye	Others
Dabsyl chloride is an amine derivatizing agent, able to give rise to stable products that can be easily monitored spectrophotometrically at 460 nm; Dabsyl chloride also used for labeling amino acids.

HY-151682

H-L-Lys(Norbornene-methoxycarbonyl)-OH	ADC Linker	Others
H-L-Lys(Norbornene-methoxycarbonyl)-OH, a norbornene-derivatized lysine, can be click-functionalized. H-L-Lys(Norbornene-methoxycarbonyl)-OH can be used for the mild and selective modification of proteins in a copper-free click reaction .

HY-151682A

H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride	ADC Linker	Others
H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride, a norbornene-derivatized lysine, can be click-functionalized. H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride can be used for the mild and selective modification of proteins in a copper-free click reaction .

HY-P2493

(Cys47)-HIV-1 tat Protein (47-57)	HIV	Others
(Cys47)-HIV-1 tat Protein (47-57) has membrane translocation function and can be used to derivatize the surface of magnetic pharmaceuticals and substantially facilitated their uptake into target cells .

HY-D1730

AF488 NHS ester	Fluorescent Dye	Others
AF488 NHS ester is an amine specific fluorescence probe (Em=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization .

HY-161071

Antioxidant/anticancer agent 1	Others	Infection Cancer
Antioxidant/anticancer agent 1 (compound 5) is a pyrimidine-derivatized Schiff base based on pyrimidine hydroxy-1-naphthaldehyde and has antibacterial, antioxidant, antifungal, and anticancer properties. Antioxidant/anticancer agent 1 .

HY-D1254

Trx-red NBL-SS perchlorate	Fluorescent Dye	Others
Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derivatized from the nile blue fluorophore. Trx-red is used for selectively imaging thioredoxin (Trx) in live cells and in vivo (λex=615 nm, λem=661 nm) .

HY-P3580

Acetyl Gastric Inhibitory Peptide (human) Human N-acetyl GIP	Insulin Receptor	Metabolic Disease Endocrinology
Acetyl Gastric Inhibitory Peptide (human) is a fatty acid derivatized analog of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties. Acetyl Gastric Inhibitory Peptide (human) can be used for research of diabetes, insulin resistance and obesity .

HY-P3580A

Acetyl Gastric Inhibitory Peptide (human) (TFA) Human N-acetyl GIP TFA	Insulin Receptor	Metabolic Disease Endocrinology
Acetyl Gastric Inhibitory Peptide (human) TFA is a fatty acid derivatized analog of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties. Acetyl Gastric Inhibitory Peptide (human) TFA can be used for research of diabetes, insulin resistance and obesity .

HY-149872

DCA-RMR1	Biochemical Assay Reagents	Others
DCA-RMR1 is a cross-linker. DCA-RMR1 elicits facile bicyclization of native peptides via N-terminus Cys-Cys cross-linking. DCA-RMR1 derivatizes RMR1 with 1,3-dichloroacetone (DCA) .

HY-W074541

Girard’s reagent T Trimethylacetohydrazideammonium chloride	Biochemical Assay Reagents	Others
Girard's reagent T is often used in analytical chemistry as a derivatizing agent for carbonyl compounds. Girard's reagent T reacts with ketones and aldehydes to form stable hydrazones that can be readily analyzed by various techniques including chromatography and spectrophotometry. In addition, Girard's Reagent T has been used in the synthesis of a variety of organic compounds, including pharmaceuticals and agrochemicals.

HY-Y0469

1-Aminohydantoin hydrochloride	Drug Metabolite	Others
1-Aminohydantoin hydrochloride is a major metabolite of nitrofurantoin in animal tissues and can be used as a standard for the determination of residues of veterinary agents in meat, milk et.al. 1-Aminohydantoin hydrochloride covalently binds to tissue proteins and is released from the tissues under slightly acidic conditions and derivatized with 2-nitrobenzaldehyde to form nitrophenyl derivatives of AHD before detection .

HY-141464

Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH Fmoc-Asn(Ac3AcNH-beta-Glc)-OH	Amino Acid Derivatives	Cancer
Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH (Fmoc-Asn(Ac3AcNH-beta-Glc)-OH) can be used in the synthesis of silicon-fluoride acceptor (SiFA) derivatized octreotate derivatives. SiFA-octreotate analogues, as tumor imaging agents, are useful tool for the research of positron emission tomography (PET) .

HY-161242

CBI1	Bcl-2 Family	Cancer
CBI1 is a covalent BAX inhibitor. CBI1 selectively derivatizes BAX at C126 and inhibits BAX activation by triggering ligands or point mutagenesis. CBI1 blocks t-2-hex lipidation and oligomerization of BAX. CBI1 inhibits BAX activation induced by BH3 ligands, F116A mutagenesis or t-2-hex .

HY-Y1968A

Sterile 10 mM Histidine, pH 5.5 buffer	Biochemical Assay Reagents	Others
Sterile 10 mM Histidine, pH 5.5 buffer is a multi-purpose buffer solution with important applications in many fields such as protein purification, vaccine preparation, drug development, cell culture and electrophoresis. Histidine is an amino acid with good buffering capacity. Sterile 10 mM Histidine, pH 5.5 buffer The sterility and specific pH conditions make it ideal for experiments that require precise control of environmental conditions. The histidine in Sterile 10 mM Histidine, pH 5.5 buffer derivatizes photosensitizers that accumulate and increase greatly upon exposure to light. Histidine-derived photosensitizers are also the primary mediators of tryptophan photooxidation .

Cat. No.	Product Name	Type

HY-101890

Dabsyl chloride 2 Publications Verification DABS-Cl	Protein Labeling
Dabsyl chloride is an amine derivatizing agent, able to give rise to stable products that can be easily monitored spectrophotometrically at 460 nm; Dabsyl chloride also used for labeling amino acids.

HY-W320397

4-(2-Aminoethylamino)-7-(N,N-dimethylsulfamoyl)benzofurazan	Fluorescent Dyes/Probes
4-(2-Aminoethylamino)-7-(N,N-dimethylsulfamoyl)benzofurazan is a precolumn fluorescence derivatization reagent.

HY-D0035

MPAC-Br

Fluorescent Dyes/Probes

MPAC-Br is a highly sensitive fluorescent derivatization reagent for carboxylic acids in HPLC .

MPAC-Br	Fluorescent Dyes/Probes
MPAC-Br is a highly sensitive fluorescent derivatization reagent for carboxylic acids in HPLC .

HY-D1254

Trx-red NBL-SS perchlorate	Fluorescent Dyes/Probes
Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derivatized from the nile blue fluorophore. Trx-red is used for selectively imaging thioredoxin (Trx) in live cells and in vivo (λex=615 nm, λem=661 nm) .

Cat. No.	Product Name	Type

HY-W074541

Girard’s reagent T Trimethylacetohydrazideammonium chloride	Biochemical Assay Reagents
Girard's reagent T is often used in analytical chemistry as a derivatizing agent for carbonyl compounds. Girard's reagent T reacts with ketones and aldehydes to form stable hydrazones that can be readily analyzed by various techniques including chromatography and spectrophotometry. In addition, Girard's Reagent T has been used in the synthesis of a variety of organic compounds, including pharmaceuticals and agrochemicals.

Girard’s reagent T

Trimethylacetohydrazideammonium chloride

Biochemical Assay Reagents

Girard's reagent T is often used in analytical chemistry as a derivatizing agent for carbonyl compounds. Girard's reagent T reacts with ketones and aldehydes to form stable hydrazones that can be readily analyzed by various techniques including chromatography and spectrophotometry. In addition, Girard's Reagent T has been used in the synthesis of a variety of organic compounds, including pharmaceuticals and agrochemicals.

HY-Y1968A

Sterile 10 mM Histidine, pH 5.5 buffer	Biochemical Assay Reagents
Sterile 10 mM Histidine, pH 5.5 buffer is a multi-purpose buffer solution with important applications in many fields such as protein purification, vaccine preparation, drug development, cell culture and electrophoresis. Histidine is an amino acid with good buffering capacity. Sterile 10 mM Histidine, pH 5.5 buffer The sterility and specific pH conditions make it ideal for experiments that require precise control of environmental conditions. The histidine in Sterile 10 mM Histidine, pH 5.5 buffer derivatizes photosensitizers that accumulate and increase greatly upon exposure to light. Histidine-derived photosensitizers are also the primary mediators of tryptophan photooxidation .

Sterile 10 mM Histidine, pH 5.5 buffer

Biochemical Assay Reagents

Sterile 10 mM Histidine, pH 5.5 buffer is a multi-purpose buffer solution with important applications in many fields such as protein purification, vaccine preparation, drug development, cell culture and electrophoresis. Histidine is an amino acid with good buffering capacity. Sterile 10 mM Histidine, pH 5.5 buffer The sterility and specific pH conditions make it ideal for experiments that require precise control of environmental conditions. The histidine in Sterile 10 mM Histidine, pH 5.5 buffer derivatizes photosensitizers that accumulate and increase greatly upon exposure to light. Histidine-derived photosensitizers are also the primary mediators of tryptophan photooxidation .

Cat. No.	Product Name	Target	Research Area

HY-P3580A

Acetyl Gastric Inhibitory Peptide (human) (TFA) Human N-acetyl GIP TFA	Insulin Receptor	Metabolic Disease Endocrinology
Acetyl Gastric Inhibitory Peptide (human) TFA is a fatty acid derivatized analog of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties. Acetyl Gastric Inhibitory Peptide (human) TFA can be used for research of diabetes, insulin resistance and obesity .

HY-P2493

(Cys47)-HIV-1 tat Protein (47-57)	HIV	Others
(Cys47)-HIV-1 tat Protein (47-57) has membrane translocation function and can be used to derivatize the surface of magnetic pharmaceuticals and substantially facilitated their uptake into target cells .

HY-P3580

Acetyl Gastric Inhibitory Peptide (human) Human N-acetyl GIP	Insulin Receptor	Metabolic Disease Endocrinology
Acetyl Gastric Inhibitory Peptide (human) is a fatty acid derivatized analog of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties. Acetyl Gastric Inhibitory Peptide (human) can be used for research of diabetes, insulin resistance and obesity .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N12840

Logmalicid B	Structural Classification Iridoids Cornaceae Cornus officinalis Sieb. et Zucc. Terpenoids Source classification Plants	Others
Logmalicid B is an iridoid glycoside compound that can be isolated from Cornus officinalis and can be used in diabetes research .

Cat. No.	Product Name		Classification

HY-151682

H-L-Lys(Norbornene-methoxycarbonyl)-OH		Labeling and Fluorescence Imaging TCO
H-L-Lys(Norbornene-methoxycarbonyl)-OH, a norbornene-derivatized lysine, can be click-functionalized. H-L-Lys(Norbornene-methoxycarbonyl)-OH can be used for the mild and selective modification of proteins in a copper-free click reaction .

HY-151682A

H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride		Labeling and Fluorescence Imaging TCO
H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride, a norbornene-derivatized lysine, can be click-functionalized. H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride can be used for the mild and selective modification of proteins in a copper-free click reaction .

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Fluorescent Dye

Biochemical Assay Reagents

Peptides

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Click Chemistry

derivatization

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

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Click Chemistry

Natural
Products