disc

By Targets:	Apoptosis (2) Bacterial (1) Caspase (1) Endogenous Metabolite (1) Fluorescent Dye (2) Keap1-Nrf2 (1) nAChR (2) NF-κB (1) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (1) Endocrinology (1) Infection (1) Inflammation/Immunology (4) Neurological Disease (3)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0085

DiSC3(5)	Fluorescent Dye	Others
DiSC3(5) is a fluorescent probe commonly used as a tracer dye to evaluate mitochondrial membrane potential. The excitation/emission wavelength of DiSC3(5) is up to 622/670 nm. DiSC3(5) can inhibit the respiratory system associated with mitochondrial NAD, and the IC₅₀ value is 8 μM. DiSC3(5) in the presence of Na ⁺/K ⁺-ATPase inhibitor ouabain 2 can induce membrane hyperpolarization of Ehrlich ascites tumor cells .

HY-N6812

Karacoline	NF-κB	Endocrinology
Karacoline, a diterpene alkaloid found in the plant Aconitum kusnezoffii, reduces degradation of the extracellular matrix (ECM) in intervertebral disc degeneration (IDD) via the NF-κB signaling pathway .

HY-D1626

DiSC18(3)

3,3'-Dioctadecylthiacarbocyanine perchlorate
Fluorescent Dye Others

DiSC18(3) is a lipophilic carbocyanine dye for membrane labelling .

DiSC18(3) 3,3'-Dioctadecylthiacarbocyanine perchlorate	Fluorescent Dye	Others
DiSC18(3) is a lipophilic carbocyanine dye for membrane labelling .

HY-RS03781

DISC1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
DISC1 Human Pre-designed siRNA Set A contains three designed siRNAs for DISC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

DISC1 Human Pre-designed siRNA Set A DISC1 Human Pre-designed siRNA Set A

HY-108909

Chymopapain	Endogenous Metabolite	Neurological Disease Inflammation/Immunology
Chymopapain is a non-specific proteo-glycanase derived from the papaya plant. Chymopapain directly into the intervertebral disc caused disc narrowing due to dissolution of the extruded material. Chymopapain has the potential for the research of herniated lumbar discs .

HY-113614

Tetrahydrobostrycin	Bacterial	Infection
Tetrahydrobostrycin is a secondary metabolite from Aspergillus sp., which exhibits a weak inhibitory activity against Staphylococcus aureus and Escherichia coli (100 mg/disc with the inhibition zones of 15 and 9.2 mm in diameter) .

HY-B1700A

Mivacurium dichloride	nAChR	Neurological Disease
Mivacurium dichloride is a benzylisoquinoline derivative and is a short-acting non-depolarizing neuromuscular blocking agent and skeletal muscle relaxant. Mivacurium dichloride couples with the nAChR to reduce or inhibit the depolarizing effect of acetylcholine on the terminal disc of the muscle cell .

HY-B1700AR

Mivacurium dichloride (Standard)	nAChR	Neurological Disease
Mivacurium (dichloride) (Standard) is the analytical standard of Mivacurium (dichloride). This product is intended for research and analytical applications. Mivacurium dichloride is a benzylisoquinoline derivative and is a short-acting non-depolarizing neuromuscular blocking agent and skeletal muscle relaxant. Mivacurium dichloride couples with the nAChR to reduce or inhibit the depolarizing effect of acetylcholine on the terminal disc of the muscle cell .

HY-N2292

Kinsenoside 1 Publications Verification	Keap1-Nrf2 Apoptosis	Inflammation/Immunology
Kinsenoside is the main active ingredient of the genus plant, and has various biological activities. Kinsenoside and Nrf2 depend on the protection of nuclear cells (NPCs), which significantly reduces their ability to survive. Kinsenoside Active NPC Medium AKT-ERK1/2-Nrf2 Signal passage, Prevent physical decline, aging, harmonious physical function impairment. Kinsenoside can improve the puncture guide model for intermediate vertebral wall discharge (IDD).

HY-P10326

Z-ATAD-FMK	Caspase Apoptosis	Cancer
Z-ATAD-FMK is an inhibitor of caspase-12. Z-ATAD-FMK is an inhibitor of caspase-12. Z-ATAD-FMK prevents endoplasmic reticulum stress-mediated apoptosis by inhibiting the activity of caspase-12 and reducing the activity of caspase-9 .

Cat. No.	Product Name	Type

HY-D0085

DiSC3(5)	Fluorescent Dyes/Probes
DiSC3(5) is a fluorescent probe commonly used as a tracer dye to evaluate mitochondrial membrane potential. The excitation/emission wavelength of DiSC3(5) is up to 622/670 nm. DiSC3(5) can inhibit the respiratory system associated with mitochondrial NAD, and the IC₅₀ value is 8 μM. DiSC3(5) in the presence of Na ⁺/K ⁺-ATPase inhibitor ouabain 2 can induce membrane hyperpolarization of Ehrlich ascites tumor cells .

DiSC3(5)

Fluorescent Dyes/Probes

DiSC3(5) is a fluorescent probe commonly used as a tracer dye to evaluate mitochondrial membrane potential. The excitation/emission wavelength of DiSC3(5) is up to 622/670 nm. DiSC3(5) can inhibit the respiratory system associated with mitochondrial NAD, and the IC₅₀ value is 8 μM. DiSC3(5) in the presence of Na ⁺/K ⁺-ATPase inhibitor ouabain 2 can induce membrane hyperpolarization of Ehrlich ascites tumor cells .

HY-D1626

DiSC18(3)

3,3'-Dioctadecylthiacarbocyanine perchlorate
Fluorescent Dyes/Probes

DiSC18(3) is a lipophilic carbocyanine dye for membrane labelling .

DiSC18(3) 3,3'-Dioctadecylthiacarbocyanine perchlorate	Fluorescent Dyes/Probes
DiSC18(3) is a lipophilic carbocyanine dye for membrane labelling .

Cat. No.	Product Name	Target	Research Area

HY-P10326

Z-ATAD-FMK	Caspase Apoptosis	Cancer
Z-ATAD-FMK is an inhibitor of caspase-12. Z-ATAD-FMK is an inhibitor of caspase-12. Z-ATAD-FMK prevents endoplasmic reticulum stress-mediated apoptosis by inhibiting the activity of caspase-12 and reducing the activity of caspase-9 .

Cat. No.	Product Name	Target	Research Area

HY-P990446

Anti-IL-15 Antibody (DISC0280)

disc0280
Inhibitory Antibodies Inflammation/Immunology
HY-P990498

Anti-RGMC/HFE2 Antibody (DISC-0974)

disc-0974
Inhibitory Antibodies Inflammation/Immunology

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N6812

Karacoline	Structural Classification Classification of Application Fields Terpenoids Source classification Ranunculaceae Diterpenoids Aconitum carmichaeli Debx. Plants Disease Research Fields Endocrinology	NF-κB
Karacoline, a diterpene alkaloid found in the plant Aconitum kusnezoffii, reduces degradation of the extracellular matrix (ECM) in intervertebral disc degeneration (IDD) via the NF-κB signaling pathway .

HY-N2292

Kinsenoside 1 Publications Verification	Structural Classification Natural Products Classification of Application Fields Orchidaceae Plants Anoectochilus Inflammation/Immunology Disease Research Fields	Keap1-Nrf2 Apoptosis
Kinsenoside is the main active ingredient of the genus plant, and has various biological activities. Kinsenoside and Nrf2 depend on the protection of nuclear cells (NPCs), which significantly reduces their ability to survive. Kinsenoside Active NPC Medium AKT-ERK1/2-Nrf2 Signal passage, Prevent physical decline, aging, harmonious physical function impairment. Kinsenoside can improve the puncture guide model for intermediate vertebral wall discharge (IDD).

HY-108909

Chymopapain	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
Chymopapain is a non-specific proteo-glycanase derived from the papaya plant. Chymopapain directly into the intervertebral disc caused disc narrowing due to dissolution of the extruded material. Chymopapain has the potential for the research of herniated lumbar discs .

HY-113614

Tetrahydrobostrycin	Structural Classification Microorganisms Source classification Phenols Polyphenols	Bacterial
Tetrahydrobostrycin is a secondary metabolite from Aspergillus sp., which exhibits a weak inhibitory activity against Staphylococcus aureus and Escherichia coli (100 mg/disc with the inhibition zones of 15 and 9.2 mm in diameter) .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82685

DISC1 Antibody (YA2430)

C1orf136; disc1; KIAA0457; RP4-730B13.1; SCZD9
WB, IHC-P, ICC/IF, IP, FC Human, Mouse, Rat


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