Search Result
Results for "
electron
" in MedChemExpress (MCE) Product Catalog:
12
Biochemical Assay Reagents
16
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-32247
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Others
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Others
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DCAF is an electron-deficient azaacene and acts as an electron injection material for organic light-emitting diodes .
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- HY-113325
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NADP
4 Publications Verification
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Endogenous Metabolite
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Others
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NADP, a nicotinamide adenine dinucleotide, is a redox cofactor. NADP is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP +) and reduced (NADPH). NADPH is the universal electron donor in cellular reductive biosyntheses and detoxification processes, and also plays a key role in oxidative defense system .
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- HY-W128525
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- HY-N10516
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Others
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Others
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Bacteriopheophytin, a photosynthetic pigment, is a bacterial demagnetised chlorophyll composed of bacterial chlorophyll in which two hydrogen atoms replace the magnesium center. Bacteriopheophytin acts as an electron acceptor in the purple bacterial reaction center (RC) and is involved in electron transfer .
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- HY-N11913
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Biochemical Assay Reagents
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Others
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Siderin is a Photosystem II inhibitor that effectively inhibits ATP synthesis and chloroplast electron transport during photosynthesis in isolated spinach. Siderin can be used in the study of plant photosynthesis .
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- HY-F0002
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Sodium NADP
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Endogenous Metabolite
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Others
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NADP sodium salt is the sodium salt form of NADP (HY-113325). NADP, a nicotinamide adenine dinucleotide, is a redox cofactor. NADP is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP +) and reduced (NADPH). NADPH is the universal electron donor in cellular reductive biosyntheses and detoxification processes, and also plays a key role in oxidative defense system .
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- HY-F0002A
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Disodium NADP
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Endogenous Metabolite
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Others
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NADP disodium salt is the disodium salt form of NADP (HY-113325). NADP, a nicotinamide adenine dinucleotide, is a redox cofactor. NADP is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP +) and reduced (NADPH). NADPH is the universal electron donor in cellular reductive biosyntheses and detoxification processes, and also plays a key role in oxidative defense system .
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- HY-114197
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- HY-130055
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HQNO
1 Publications Verification
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Mitochondrial Metabolism
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Infection
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HQNO, secreted by P. aeruginosa, is a potent electron transport chain inhibitor with a Kd of 64 nM for complex III . HQNO is a potent inhibitor of mitochondrial NDH-2 in many species .
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- HY-B1848
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Others
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Others
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Hexazinone is a nonselective herbicide from the triazine family. Hexazinone binds to the D-1 quinone protein of the electron transport chain in photosystem II to inhibit the photosynthesis .
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- HY-B1849
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Others
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Infection
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Hexazinone is a nonselective herbicide from the triazine family. Hexazinone binds to the D-1 quinone protein of the electron transport chain in photosystem II to inhibit the photosynthesis .
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- HY-112177
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Fungal
Mitochondrial Metabolism
Antibiotic
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Infection
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Myxothiazol, an antifungal antibiotic, is a mitochondrial electron transport chain complex III (bc1 complex) inhibitor. Myxothiazol inhibits the growth of many yeasts and fungi at concentrations between 0.01 and 3 μg/ml .
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- HY-N10094
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Others
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Others
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Maculosidine is a furoquinoline alkaloid that can be isolated from Balfourodendron riedelianum. Maculosidine inhibits ATP synthesis, basal, phosphorylating and uncoupled electron transport in plants. Maculosidine inhibits Hill reaction on spinach chloroplasts .
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- HY-N9680
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Ubiquinone 8
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Endogenous Metabolite
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Metabolic Disease
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Coenzyme Q8 (Ubiquinone 8) is an isoprenoid quinone that mediates electron transfer within the aerobic respiratory chain and mitigates oxidative stress. Coenzyme Q8 enhances nonspecific resistance to bacterial infections .
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- HY-N6782
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- HY-W012145
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Others
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Metabolic Disease
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TMPD dihydrochloride, a readily oxidizable compound, is an enzymatically convert redox active substrate molecule. TMPD dihydrochloride is also an electron donor and serves as a reducing cosubstrate for heme peroxidases . TMPD dihydrochloride is also a complex IV substrate .
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- HY-D1509
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Fluorescent Dye
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Others
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Phenazine ethosulfate is a cationic dye (Ex=390 nm, Em=530 nm) and an electron acceptor that can be used in dye-linked enzyme assays. Phenazine ethosulfate is an intermediate for detecting nitric oxide reducatase (Nors) activity with the presence of ascorbic acid .
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- HY-N8139
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Others
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Metabolic Disease
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2-Amino-3-carboxy-1,4-naphthoquinone is the electron transfer mediator. 2-Amino-3-carboxy-1,4-naphthoquinone changes glucose metabolism of the homofermentative lactic acid bacteria .
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- HY-103311
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Ammoniated ruthenium oxychloride
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Calcium Channel
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Cardiovascular Disease
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Ruthenium red (Ammoniated ruthenium oxychloride) is a polycationic dye widely used for electron microscopy (EM) of cells, tissues and vegetative bacteria. Ruthenium red strongly reacts with phospholipids and fatty acids and binds to acidic mucopolysaccharides. Ruthenium red is a L-type calcium current (ICa) blocker .
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- HY-101415
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Ubiquinone Q9; CoQ9; Ubiquinone 9
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Apoptosis
Endogenous Metabolite
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Cardiovascular Disease
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Coenzyme Q9 (Ubiquinone Q9), the major form of ubiquinone in rodents, is an amphipathic molecular component of the electron transport chain that functions as an endogenous antioxidant. Coenzyme Q9 attenuates the diabetes-induced decreases in antioxidant defense mechanisms. Coenzyme Q9 improves left ventricular performance and reduces myocardial infarct size and cardiomyocyte apoptosis .
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- HY-126222
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Apoptosis
Mitochondrial Metabolism
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Cancer
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MitoTam bromide, hydrobromide, a Tamoxifen derivative , is an electron transport chain (ETC) inhibitor. MitoTam bromide, hydrobromide reduces mitochondrial membrane potential in senescent cells and affects mitochondrial morphology . MitoTam bromide, hydrobromide is an effective anticancer agent, suppresses respiratory complexes (CI-respiration) and disrupts respiratory supercomplexes (SCs) formation in breast cancer cells .
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- HY-126222A
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Apoptosis
Mitochondrial Metabolism
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Cancer
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MitoTam iodide, hydriodide is a Tamoxifen derivative , an electron transport chain (ETC) inhibitor, spreduces mitochondrial membrane potential in senescent cells and affects mitochondrial morphology .
MitoTam iodide, hydriodide is an effective anticancer agent, suppresses respiratory complexes (CI-respiration) and disrupts respiratory supercomplexes (SCs) formation in breast cancer cells . MitoTam iodide, hydriodide causes apoptosis .
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- HY-110282
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Oxidative Phosphorylation
Mitochondrial Metabolism
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Metabolic Disease
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S3QEL-2, a suppressor of superoxide production from mitochondrial complex III, potently and selectively suppresses site IIIQo superoxide production (IC50=1.7 μM). S3QEL-2 does not affect oxidative phosphorylation, and normal electron flux. S3QEL-2 inhibits HIF-1α accumulation .
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- HY-D0190
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HTTA; TTA; TTFA
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Biochemical Assay Reagents
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Infection
Others
Cancer
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2-Thenoyltrifluoroacetone is a chelating agent. 2-Thenoyltrifluoroacetone can be used for the complexation of various metal ions including Mn(II), Co(III), Ni(II), et al.. 2-Thenoyltrifluoroacetone possesses antitubercular and cytotoxic activities. 2-Thenoyltrifluoroacetone is also used as common inhibitor of mitochondrial electron flux and to analyze the endothelial cell dysfunction. Besides, copper (II) complex of 2-Thenoyltrifluoroacetone has anticancer activity against K562 .
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- HY-B0166
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-
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- HY-129460
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Reactive Oxygen Species
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Neurological Disease
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XJB-5-131 is a mitochondria-targeted ROS and electron scavenger . XJB-5-131 is a bi-functional antioxidant that comprises a radical scavenger. XJB-5-131 is a synthetic antioxidant that targets mitochondria . XJB-5-131 is an effective ionizing irradiation protector and mitigator of cord blood mononuclear cells (CB MNCs) .
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- HY-B0166GL
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L-Ascorbate (GMP Like); Vitamin C (GMP Like)
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Reactive Oxygen Species
Apoptosis
Calcium Channel
Endogenous Metabolite
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Neurological Disease
Metabolic Disease
Cancer
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L-Ascorbic acid (GMP Like) is the GMP Like class L-Ascorbic acid (HY-B0166). L-Ascorbic acid (L-Ascorbate, Vitamin C), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .
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- HY-D1373
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HBC 530
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DNA Stain
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Cancer
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HBC is a green fluorescent protein (GFP) fluorophore-like synthetic dye, with a structurally rigid electron acceptor and a strong electron donor. HBC is used to detect RNA localization .
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- HY-B0166S8
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L-Ascorbate-1; Vitamin C-13C6-1
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Isotope-Labeled Compounds
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Cancer
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L-Ascorbic acid- 13C6-1 (L-Ascorbate-1; Vitamin C- 13C6-1) is a 13C labeled L-Ascorbic acid (HY-B0166) . L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .
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- HY-15920
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INT
2 Publications Verification
Iodonitrotetrazolium chloride; p-Iodonitrotetrazolium Violet
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Biochemical Assay Reagents
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Others
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INT(Iodonitrotetrazolium chloride) is used in various dehydrogenase colorimetric analysis of the electron acceptor.
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- HY-E70306
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Endogenous Metabolite
Parasite
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Infection
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Zymolyase, Arthrobacter luteus, is a zymolyase mainly found in Arthrobacter luteus. Enzyme, an enzyme with beta-1,3 glucanase activity, removes the electron-dense outer layer of the Plasmodium karinii cell wall, exposing an electron-lucent layer .
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- HY-121939
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- HY-N0111
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- HY-119984
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Others
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Others
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DNP-INT is a potent photosynthetic electron transport chain (PETC) inhibitor. DNP-INT competently inhibits the oxidation of plastid quinoline by binding to the Q0 site of Cyt-b6f (Kd=1.4 nM), thereby inhibiting electron transfer in plants .
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- HY-W040201
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3-[3-(Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate
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Biochemical Assay Reagents
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Others
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CHAPSO is a zwitterionic detergent that is thermally stable. CHAPSO is able to broaden the particle orientation distribution, enabling single-particle cryo-electron microscopy (cryo-EM) to produce isotropically uniform maps. CHAPSO can eliminate the directional bias of bacterial transcription complexes and help determine the structure of bacterial transcription complexes under cryo-electron microscopy .
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- HY-156137
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- HY-134240
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Magnesium L-threonate
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Drug Metabolite
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Metabolic Disease
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L-Threonic acid magnesium salt is the enantiomer of Threonic acid and a metabolite of vitamin C. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent .
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- HY-E70276
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- HY-B1756
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- HY-120338
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- HY-147151
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Others
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Others
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AMCPy is a potent electron paramagnetic resonance (EPR) brain imaging agent, possessing excellent lipophilicity for blood−brain barrier (BBB) penetration .
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- HY-W020043
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Fungal
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Infection
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Pyribencarb is a benzylcarbamate-type fungicide, which is active against a wide range of plant pathogenic fungi. Pyribencarb is a potent Qo inhibitor of cytochrome b. Pyribencarb is especially active against Botrytis cinerea and Sclerotinia sclerotirum .
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- HY-121214
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Mitochondrial Metabolism
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Infection
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Amisulbrom is a sulfonamide fungicide used to control oomycete diseases. Amisulbrom biochemically inhibits the cytochrome-bc1 complex of the mitochondrial electron transport system .
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- HY-131501
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Others
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Metabolic Disease
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Menaquinone 9 is a vitamin K2 (HY-109569) analog. Menaquinone 9 acts as a prothrombogenic agent and functional electron transfer component in nitrate reductase .
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- HY-125857
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- HY-D0937
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1-Methoxy PMS; 1-Methoxyphenazine methosulfate
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Reactive Oxygen Species
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Others
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Methoxy-PMS (1-Methoxy PMS), an active oxygen formation inducer, is stable electron-transport mediator between NAD(P)H and tetrazolium dyes .
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- HY-113325A
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Endogenous Metabolite
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Others
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NADP sodium hydrate, a β-Nicotinamide adenine dinucleotide phosphate sodium salt, is a redox cofactor. NADP sodium hydrate is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP +) and reduced (NADPH) .
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- HY-137179
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Biochemical Assay Reagents
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Others
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Glyco-diosgenin is a synthetic surfactant and detergent for extracting proteins from membranes for structure and function studies, and single-particle cryo-electron microscopy (cryoEM) studies of membrane proteins .
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- HY-14572
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SN 27858
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DNA Alkylator/Crosslinker
Drug Metabolite
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Cancer
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PR-104A (SN 27858) is the alcohol metabolite of phosphate proagent PR-104. PR-104A is a hypoxia-selective DNA cross-linking agent/DNA-damaging agent and cytotoxin. Antitumor Activity . PR-104A is metabolized under hypoxia by the 1-electron NADPH:cytochrome P450 oxidoreductase. PR-104A can be used for the research of relapsed/refractory T-lineage acute lymphoblastic leukemia (T-ALL) .
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- HY-17513
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BAY314666; BAY-MKH 3586
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Others
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Others
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Amicarbazone(BAY-MKH3586; BAY314666) is a potent inhibitor of photosynthetic electron transport via binding to the Qb domain of photosystem II (PSII); herbicide with a broad spectrum of weed control.
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- HY-N0111S2
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- HY-136355
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Fungal
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Infection
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Picoxystrobin is a primary strobilurin fungicide that is widely applied for plant disease control. Picoxystrobin inhibits mitochondrial respiration via blocking electron transfer at the Qo center of cytochrome b and c1 .
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- HY-125921
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Fluorescent Dye
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WST-3 is a water-soluble tetrazolium dye. In the presence of an electron mediator, WST-3 is reduced to WST-3 formazan by NADH and displays an absorption maxima of 433 nM .
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- HY-N0111S
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- HY-D1651
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Fluorescent Dye
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Others
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BDP 630/650 amine is a far-red luminescent, boron-dipyridyl fluorophore. BDP 630/650 amine can label various electron-loving compounds. (λex=630 nm, λem=650 nm).
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- HY-144721
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Bacterial
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Infection
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Antitubercular agent-11 (Compound 1e) is an antitubercular agent. Antitubercular agent-11 with a bulkier electron-donating group (Bu-t) demonstrated the best MIC value of 0.060 μg/mL .
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- HY-157070
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Others
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Others
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SCO-L-Lysine contains a SCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. SCO-L-Lysine can be incorporated into the protein of interest by the tRNAPyl/PylRSAF synthetase .
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- HY-120976
-
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Others
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Cancer
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cDEPMPO is a potent anticancer proagent. High concentrations of DEPMPO spin-trap the ·OH radical together with aryl radicals arising from one-electron reduced BTO (benzotriazine 1,4-di-N-oxide) compounds .
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- HY-149203A
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Fluorescent Dye
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Others
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MQA-P is a multifunctional near-infrared (NIR) fluorescent probe that simultaneously detects ONOO -, viscosity, and polarity within mitochondria. MQA-P exhibits significant response to ONOO -, λem=645 nm; and NIR channel at λem>704 nm Medium is highly sensitive to viscosity/polarity. MQA-P possesses excited-state intramolecular charge transfer (ESICT) properties that are highly sensitive to polarity by designing the N,N-dimethylamino group as the electron donor and the quinoline cation unit as the electron acceptor. MQA-P is used for ferroptosis or cancer diagnosis in vitro and in vivo via dual-channel images .
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- HY-W020768
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Biochemical Assay Reagents
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Cancer
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Fullerene-C60, a representative of carbon nanocompounds, is suggested to be promising agent for application in photodynamic research due to its unique physicochemical properties. Fullerene-C60 probes the intramolecular dynamics of its electron and energy transfer .
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- HY-125830
-
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Others
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Others
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ITIC, non-fullerene acceptor, is an indacenodithienothiophene-based postfullerene electron acceptor, crystallizes in a profoundly different way as compared to fullerenes.
ITIC has a superior thermal stability and undergoes a glass-crystal transition considerably below its high Tg of 180 °C.
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- HY-D1646
-
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Fluorescent Dye
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Others
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BDP TR methyltetrazine is a BDP dye linker containing a methyltetrazine group. BDP TR methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-B1849S
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Isotope-Labeled Compounds
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Infection
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Hexazinone-d6 is the deuterium labeled Hexazinone[1]. Hexazinone is a nonselective herbicide from the triazine family. Hexazinone binds to the D-1 quinone protein of the electron transport chain in photosystem II to inhibit the photosynthesis[2].
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- HY-151698B
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Biochemical Assay Reagents
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Others
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(R,E)-TCO-NHS Ester is a Click Amino Acid that can be used to label amine-containing compounds or biomolecules. TCO-NHS ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
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- HY-151698A
-
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Biochemical Assay Reagents
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Others
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(S,E)-TCO-NHS Ester is a Click Amino Acid that can be used to label amine-containing compounds or biomolecules. TCO-NHS ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
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- HY-D2236
-
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Fluorescent Dye
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Others
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SiR-tetrazine is a Tetrazine modified SiR (silicon rhodamine) fluorescent dye. SiR-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .
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- HY-B0456
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Vitamin B2; E101
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Endogenous Metabolite
Bacterial
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Metabolic Disease
Cancer
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Riboflavin, an orally active and easily absorbed micronutrient, is a precursor of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which serve as coenzymes for numerous enzymatic reactions and perform key metabolic functions by mediating the transfer of electrons in biological oxidation-reduction reaction .
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- HY-B0166A
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Sodium ascorbate; Sodium L-ascorbate; Vitamin C sodium salt; Vitamine C sodium salt
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Calcium Channel
Reactive Oxygen Species
Apoptosis
Endogenous Metabolite
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Cancer
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L-Ascorbic acid sodium salt (Sodium ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid sodium salt selectively inhibits Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid sodium salt is also a collagen deposition enhancer and an elastogenesis inhibitor .
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- HY-125831
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Biochemical Assay Reagents
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Others
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ITIC-4F is an indacenodithienothiophene (IDTT)-based postfullerene electron acceptor.
ITIC-4F has broad applicability in high-efficiency binary and ternary single-junction as well as tandem polymer solar cells (PSCs) .
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- HY-151698
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ADC Linker
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Others
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TCO-NHS Ester axial is a click chemistry reagent that can be used as a building block in amine reactions. TCO-NHS Ester axial contains TCO groups, which can undergo inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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- HY-D2235
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Fluorescent Dye
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Others
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SiR-Me-tetrazine is a Tetrazine modified SiR (silicon rhodamine) fluorescent dye. SiR-Me-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-124480
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PROTAC Linkers
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Cancer
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Tetrazine-Ph-acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-acid is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-136095
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ADC Linker
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Cancer
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Tetrazine-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-136104
-
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ADC Linker
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Cancer
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Methyltetrazine-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-Maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-N9610
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Ubiquinone 30
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Endogenous Metabolite
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Inflammation/Immunology
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Coenzyme Q6 (Ubiquinone 30) is an isoprenylated benzoquinone lipid. Coenzyme Q6 exhibits functions in respiratory electron transport and as a lipid antioxidant. Coenzyme Q6 also has antioxidant effects, which can prevent the production of free radicals and oxidative damage .
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- HY-149998
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Bacterial
Reactive Oxygen Species
Apoptosis
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Infection
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Antimycobacterial agent-5 (compound 27) is an imidazopyridine amide targeting mycobacterial electron transport chain (ETC) airway CIII2CIV2 supercomplexes. The IC50 value of Antimycobacterial agent-5 against Mycobacterium smegmatisCIII2CIV2 is 441 nM .
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- HY-155849
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Pyruvate Kinase
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Cancer
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Pkm2-in-4 (compound 5C) is a selective inhibitor of PKM2 (IC50=0.35 μM), which regulates pyruvate-dependent respiration and induces mitochondrial H202 production rate and electron transport system coupling .
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- HY-126908
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PROTAC Linkers
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Cancer
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Tetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-130283
-
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PROTAC Linkers
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Cancer
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Methyltetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-Ph-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-136032
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ADC Linker
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Cancer
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Tetrazine-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-136033
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ADC Linker
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Cancer
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Methyltetrazine-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-136039
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ADC Linker
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Cancer
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TCO-SS-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-SS-amine is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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- HY-130928
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ADC Linker
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Cancer
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Tetrazine-Ph-OPSS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-Ph-OPSS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-136031
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ADC Linker
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Cancer
|
Tetrazine-SS-Biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-SS-Biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136406
-
|
ATP Synthase
|
Infection
Cancer
|
Bongkrekic acid is a mitochondrial toxin secreted by the bacteria Pseudomonas cocovenenans . Bongkrekic acid specific ligand for mitochondrial adenine nucleotide translocase (ANT) rather than the electron transport chain. Bongkrekic acid has to cross the mitochondrial inner membrane to produce its inhibitory effect on ADP/ATP transport .
|
-
- HY-W053709
-
(4-(1,2,4,5-Tetrazin-3-yl)phenyl)methanamine; Tetrazine-NH2
|
Biochemical Assay Reagents
|
Cancer
|
Tetrazine-Amine is a tetrazine linker that can be used to covalently label live cells through a cycloaddition . Tetrazine-Amine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-107869
-
|
Others
|
Others
|
Isoindigo is the acceptor of donor-acceptor (D-A) conjugated polymer, as well as an Indigo series dye. Isoindigo equips two lactam rings and strong electron-withdrawing character. Isoindigo can be used for dyeing and pigment preparation. Isoindigo shows high mobility and good ambient stability in FETs .
|
-
- HY-141161B
-
|
ADC Linker
|
Cancer
|
(R)-TCO-PEG8-acid is an ADC linker containing 8 PEG units. (R)-TCO-PEG8-acid can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-D2243
-
|
Fluorescent Dye
|
Others
|
Cy3.5 tetrazineis a Tetrazine modified Cy3.5 fluorescent dye. SiR-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .
|
-
- HY-W004520
-
5-Methylphenazinium methylsulfate
|
Bacterial
Antibiotic
Apoptosis
|
Others
|
Phenazine methylsulfate is a free radical generator. Phenazine methylsulfate has been used as an electron transfer reactant in cell viability assays. Phenazine methylsulfate induces ssDNA break formation in the presence of the reducing agent NADPH. Phenazine methylsulfate induces oxidative DNA damage in an alkaline comet assay and apoptosis.
|
-
- HY-B0166S6
-
-
- HY-P2910
-
GOase
|
Endogenous Metabolite
|
Others
|
Galactose Oxidase, Dactylium dendroides (GOase) from fungus is often used in biochemical studies. Galactose oxidase is a type II copper metalloenzyme, and it containing a single polypeptide. Galactose oxidase catalyzes two-electron oxidation of primary alcohols to their corresponding aldehydes, coupling with the reduction of dioxygen to hydrogen peroxide .
|
-
- HY-133504
-
|
ADC Linker
|
Cancer
|
Tetrazine-Ph-SS-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-Ph-SS-amine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-B0849
-
|
Fungal
Reactive Oxygen Species
Apoptosis
Bacterial
Phosphatase
|
Infection
|
Azoxystrobin is an orally active, broad-spectrum β-methoxyacrylate fungicide. Azoxystrobin inhibits mitochondrial respiration by binding to the Qo site of the cytochrome bc1 complex and inhibiting electron transfer. Azoxystrobin induces the production of reactive oxygen species (ROS) and induces cell apoptosis .
|
-
- HY-141167B
-
|
ADC Linker
|
Cancer
|
(S)-TCO-PEG4-NHS ester is an ADC linker containing 4 PEG units. (S)-TCO-PEG4-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-141169A
-
|
ADC Linker
|
Cancer
|
(S)-TCO-PEG8-NHS ester is an ADC linker containing 8 PEG units. (S)-TCO-PEG8-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-141169B
-
|
ADC Linker
|
Cancer
|
(R)-TCO-PEG8-NHS ester is an ADC linker containing 8 PEG units. (R)-TCO-PEG8-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-157008
-
|
ADC Linker
|
Cancer
|
(S)-TCO-PEG2-Maleimide is an ADC linker containing 2 PEG units. (S)-TCO-PEG2-Maleimide can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-N6715
-
|
Influenza Virus
Bacterial
|
Infection
|
Tenuazonic acid, belonging to tetramic acids that are the largest family of natural products, is a putative nonhost-selective mycotoxin isolated from Alternaria alternate . Tenuazonic acid blocks electron transport beyond primary quinone acceptor (QA) by interacting with D1 protein and it is a broad-spectrum and effective photosystem II (PSII) inhibitor .
|
-
- HY-140015
-
|
PROTAC Linkers
|
Cancer
|
TCO-PEG3-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . TCO-PEG3-acid is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-141286
-
|
Fluorescent Dye
|
Others
|
TAMRA-PEG4-methyltetrazine is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-methyltetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-140731
-
|
PROTAC Linkers
|
Cancer
|
TCO-PEG-TCO (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG-TCO (MW 5000) is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-141285
-
|
Fluorescent Dye
|
Others
|
TAMRA-PEG4-tetrazine is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-tetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-B0849S
-
|
Isotope-Labeled Compounds
Fungal
Reactive Oxygen Species
Apoptosis
|
Infection
|
Azoxystrobin-d4 is deuterium labeled Azoxystrobin. Azoxystrobin is a broad-spectrum β-methoxyacrylate fungicide. Azoxystrobin inhibits mitochondrial respiration by binding to the Qo site of the cytochrome bc1 complex and inhibiting electron transfer. Azoxystrobin induces the production of reactive oxygen species (ROS) and induces cell apoptosis.
|
-
- HY-B0166S2
-
-
- HY-B0166S3
-
-
- HY-B0166S4
-
-
- HY-B0166S5
-
-
- HY-156313
-
|
ADC Linker
|
Cancer
|
Me-Tet-PEG4-NHS is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156475
-
|
ADC Linker
|
Cancer
|
Me-Tet-PEG2-COOH is an ADC Linker containing 2 PEG units. Me-Tet-PEG2-COOH can use its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156476
-
|
ADC Linker
|
Cancer
|
Me-Tet-PEG2-NHS is an ADC Linker containing 2 PEG units. Me-Tet-PEG2-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156477
-
|
ADC Linker
|
Cancer
|
Me-Tet-PEG8-NHBoc is an ADC Linker containing 8 PEG units. Me-Tet-PEG8-NHBoc can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156478
-
|
ADC Linker
|
Cancer
|
Me-Tet-PEG4-NHBoc is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NHBoc can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156479
-
|
ADC Linker
|
Cancer
|
Me-Tet-PEG3-NHBoc is an ADC Linker containing 3 PEG units. Me-Tet-PEG3-NHBoc can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156490
-
|
ADC Linker
|
Cancer
|
Me-Tet-PEG5-NHS is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156491
-
|
ADC Linker
|
Cancer
|
Me-Tet-PEG9-NHS is an ADC Linker containing 9 PEG units. Me-Tet-PEG9-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156492
-
|
ADC Linker
|
Cancer
|
Me-Tet-PEG4-COOH is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156493
-
|
ADC Linker
|
Cancer
|
Me-Tet-PEG5-COOH is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156494
-
|
ADC Linker
|
Cancer
|
Me-Tet-PEG9-COOH is an ADC Linker containing 9 PEG units. Me-Tet-PEG9-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156495
-
|
ADC Linker
|
Cancer
|
Biotin-PEG3-Me-Tet is an ADC Linker containing 3 PEG units. Biotin-PEG3-Me-Tet can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-D2142
-
|
Fluorescent Dye
|
Others
|
Cy5-PEG2-TCO is a fluorescent dye that reacts with tetrazines. Cy5-PEG2-TCO contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
|
-
- HY-151691
-
|
ADC Linker
|
Others
|
Trisulfo-Cy3 Methyltetrazine is a click chemistry reagent containing an methyltetrazine group. Methyltetrazine-activated Cy3 probe reacts with TCO-containing compounds via an Inverse-Electron-Demand Diels-Alder reaction to form a stable covalent bond and does not require Cu-catalyst or elevated temperatures .
|
-
- HY-151755
-
|
Fluorescent Dye
|
Others
|
Sulfo-Cy3-Tetrazine is a click chemistry reagent containing an tetrazine group. Sulfo-Cy3-Tetrazine is water soluble cyanine fluorescence dye, which is an inverse electron demand [4+2] cycloaddition that takes place between tetrazine and trans-cyclooctene or other strained olefin.
|
-
- HY-F0001
-
Disodium NADH
|
Endogenous Metabolite
|
Metabolic Disease
|
NADH disodium salt (Disodium NADH) is an orally active reduced coenzyme. NADH disodium salt is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .
|
-
- HY-125365
-
|
Bacterial
Reactive Oxygen Species
Antibiotic
|
Infection
|
Rifamycin S, a quinone, is an antibiotic against Gram-positive bacteria (including MRSA). Rifamycin S is the oxidized forms of a reversible oxidation-reduction system involving two electrons. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation. Rifamycin S can be used for tuberculosis and leprosy .
|
-
- HY-140940
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG4-methyltetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133467
-
|
PROTAC Linkers
|
Cancer
|
Methyltetrazine-PEG5-methyltetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG5-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133468
-
|
PROTAC Linkers
|
Cancer
|
Methyltetrazine-PEG6-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG6-maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133474
-
|
PROTAC Linkers
|
Cancer
|
TCO-PEG3-oxyamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG3-oxyamine is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-133476
-
|
PROTAC Linkers
|
Cancer
|
TCO-PEG3-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG3-alcohol is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-133478
-
|
PROTAC Linkers
|
Cancer
|
TCO-PEG11-TCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG11-TCO is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-133475
-
|
PROTAC Linkers
|
Cancer
|
TCO-PEG5-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG5-maleimide is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-133505
-
|
PROTAC Linkers
|
Cancer
|
Methyltetrazine-PEG4-amine (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG4-amine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133508
-
|
PROTAC Linkers
|
Cancer
|
Methyltetrazine-PEG4-SSPy is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG4-SSPy is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133497
-
|
PROTAC Linkers
|
Cancer
|
HyNic-PEG2-TCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . HyNic-PEG2-TCO is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-B0817
-
|
Parasite
|
Infection
|
Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC50 value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function .
|
-
- HY-B0849S1
-
|
Fungal
Reactive Oxygen Species
Apoptosis
|
Infection
|
Azoxystrobin-d3 is deuterium labeled Azoxystrobin. Azoxystrobin is a broad-spectrum β-methoxyacrylate fungicide. Azoxystrobin inhibits mitochondrial respiration by binding to the Qo site of the cytochrome bc1 complex and inhibiting electron transfer. Azoxystrobin induces the production of reactive oxygen species (ROS) and induces cell apoptosis[1].
|
-
- HY-157003
-
|
ADC Linker
|
Cancer
|
(S)-TCO-PEG2-NH2 is an ADC Linker containing 2 PEG units. (S)-TCO-PEG2-NH2 can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-157006
-
|
ADC Linker
|
Cancer
|
(S)-TCO-PEG3-NH2 is an ADC linker containing 3 PEG units. (S)-TCO-PEG3-NH2 can use its own TCO group to perform the inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-157007
-
|
ADC Linker
|
Cancer
|
(S)-TCO-PEG7-NH2 is an ADC linker containing 7 PEG units. (S)-TCO-PEG7-NH2 can use its own TCO group to perform the inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-D2118
-
|
Fluorescent Dye
|
Others
|
TAMRA-PEG3-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-D2117
-
|
Fluorescent Dye
|
Others
|
TAMRA-PEG4-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG8-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-B0849R
-
|
Fungal
Reactive Oxygen Species
Apoptosis
|
Infection
|
Azoxystrobin (Standard) is the analytical standard of Azoxystrobin. This product is intended for research and analytical applications. Azoxystrobin is a broad-spectrum β-methoxyacrylate fungicide. Azoxystrobin inhibits mitochondrial respiration by binding to the Qo site of the cytochrome bc1 complex and inhibiting electron transfer. Azoxystrobin induces the production of reactive oxygen species (ROS) and induces cell apoptosis.
|
-
- HY-F0001A
-
Disodium NADH hydrate
|
Endogenous Metabolite
|
Metabolic Disease
|
NADH disodium salt (Disodium NADH) hydrate is an orally active reduced coenzyme. NADH disodium salt hydrate is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt hydrate plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .
|
-
- HY-114856
-
|
Biochemical Assay Reagents
|
Others
|
DTBT is a six-membered heterocyclic ring that is commonly used in the preparation of organic electronic devices, such as P-type organic semiconductors (OFETs) and P-type organic photodiodes (OLEDs). DTBT has good performance in electron transmission and photoelectric conversion. DTBT polymerizes to form donor-acceptor polymers, which are used to prepare solar cells .
|
-
- HY-130508
-
|
PROTAC Linkers
|
Cancer
|
Methyltetrazine-Ph-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-Ph-PEG4-azide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-130551
-
|
PROTAC Linkers
|
Cancer
|
Tetrazine-Ph-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-PEG5-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133477
-
|
PROTAC Linkers
|
Cancer
|
(S)-TCO-PEG3-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . (S)-TCO-PEG3-maleimide is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-138747
-
|
PROTAC Linkers
|
Cancer
|
Bis-sulfone-PEG4-Tetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bis-sulfone-PEG4-Tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-156300
-
|
ADC Linker
|
Cancer
|
Me-Tet-PEG4-NH2 is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NH2 can use its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156301A
-
|
ADC Linker
|
Cancer
|
Me-Tet-PEG8-NH2 (hydrochloride) is an ADC Linker containing 2 PEG units. Me-Tet-PEG8-NH2 (hydrochloride) can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-W591272
-
|
ADC Linker
|
Cancer
|
Me-Tet-PEG3-NH2 is an ADC Linker containing 3 PEG units. Me-Tet-PEG3-NH2 can use its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-D2148
-
|
Fluorescent Dye
|
Others
|
AF 430 tetrazine is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 430 nm and an emission wavelength of 542 nm. AF 430 tetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. To achieve specific coupling of dye labels and biomolecules.
|
-
- HY-N12540
-
MGDG
|
Others
|
Others
|
Monogalactosyldiacylglycerol (MGDG) is a polar lipid that does not form a bilayer and is found, for example, in the chloroplast thylakoid of aerobic photosynthetic organisms. Monogalactosyldiacylglycerol lacks charge and is highly unsaturated, which provides a fluid environment that facilitates the diffusion process of electron transfer in photosynthesis and may be used in the packaging of natural proteins. The galactolipid Monogalactosyldiacylglycerol has anti-inflammatory effects in vivo ..
|
-
- HY-140141
-
|
PROTAC Linkers
|
Cancer
|
PC Methyltetrazine-PEG4-NHS carbonate ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . PC Methyltetrazine-PEG4-NHS carbonate ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133460
-
|
PROTAC Linkers
|
Cancer
|
Tetrazine-Ph-NHCO-PEG3-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHCO-PEG3-alcohol is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133463
-
|
PROTAC Linkers
|
Cancer
|
Tetrazine-Ph-PEG5-Ph-tetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-PEG5-Ph-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133465
-
|
PROTAC Linkers
|
Cancer
|
Tetrazine-Ph-PEG4-Ph-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-PEG4-Ph-aldehyde is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133479
-
|
PROTAC Linkers
|
Cancer
|
Tetrazine-Ph-NHCO-C3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHCO-C3-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136052
-
|
ADC Linker
|
Cancer
|
Tetrazine-PEG4-oxyamine (hydrochloride) is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-oxyamine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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-
- HY-136050
-
|
ADC Linker
|
Cancer
|
TCO-PEG3-Biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG3-Biotin is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-136053
-
|
ADC Linker
|
Cancer
|
Tetrazine-PEG4-biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136056
-
|
ADC Linker
|
Cancer
|
Methyltetrazine-PEG4-oxyamine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-oxyamine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136045
-
|
ADC Linker
|
Cancer
|
APN-PEG4-tetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . APN-PEG4-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-130977
-
|
ADC Linker
|
Cancer
|
Tetrazine-PEG4-amine (hydrochloride) is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-amine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136074
-
|
ADC Linker
|
Cancer
|
Methyltetrazine-PEG4-aldehyde is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-aldehyde is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136077
-
|
ADC Linker
|
Cancer
|
TCO-PEG3-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG3-aldehyde is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-136086
-
|
ADC Linker
|
Cancer
|
Tetrazine-PEG6-amine (hydrochloride) is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG6-amine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-148211
-
|
ADC Linker
|
Cancer
|
Tetrazine-PEG7-amine hydrochloride is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG7-amine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-P2733
-
GPO
|
Endogenous Metabolite
|
Metabolic Disease
|
Glycerol-3-phosphate oxidase, E. coli (GPO) is a key intermediate in glycerol metabolism. Glycerol-3-phosphate oxidase can be extracted from Escherichia coli. Glycerol-3-phosphate oxidase is the skeleton of phospholipids in membrane lipids, and also the substrate of respiratory chain. Glycerol-3-phosphate oxidase produces electrons through oxidation .
|
-
- HY-P2890
-
Denilite IIS
|
Endogenous Metabolite
|
Others
|
Laccase, Microorganisms (Denilite IIS) is a multi-copper oxidase (MCOs), which widely exists in microorganisms, plants and fungi, and can catalyze the oxidation of one electron of various phenolic compounds. Laccase can promote the oxidative coupling of single lignin, which plays an important role in the formation and biodegradation of lignin, and also has the potential to cross-link food polymers .
|
-
- HY-125283
-
|
Mitochondrial Metabolism
|
Metabolic Disease
|
IM176OUT05 is a high solubility biguanide. IM176OUT05 activates stem cell metabolism, promotes hair regrowth and increases stemness induction and maintenance during the pluripotent stem cell generation process. IM176OUT0 inhibits mitochondrial electron transport chain (ETC) activity with an IC50 of 3.2 μM .
|
-
- HY-160258
-
GDP-Fucose-Am-Tz
|
Biochemical Assay Reagents
|
Others
|
GDP-Fucose-Tz (GDP-Fucose-Am-Tz) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. GDP-fucose-Am-Tz and TCO-ssDNA were reacted at a ratio of 1:1 to obtain the final product GDP-fucose-ssDNA .
|
-
- HY-133461
-
|
PROTAC Linkers
|
Cancer
|
Tetrazine-Ph-NHCO-PEG6-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHCO-PEG6-NH-Boc is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133462
-
|
PROTAC Linkers
|
Cancer
|
Tetrazine-Ph-NHCO-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHCO-PEG4-NH-Boc is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136040
-
|
ADC Linker
|
Cancer
|
Tetrazine-PEG4-SS-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-130945
-
|
ADC Linker
|
Cancer
|
Tetrazine-PEG5-SS-amine is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG5-SS-amine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-130947
-
|
ADC Linker
|
Cancer
|
Tetrazine-PEG4-SS-Py is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-SS-Py is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-130955
-
|
ADC Linker
|
Cancer
|
Amino-bis-PEG3-TCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Amino-bis-PEG3-TCO is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-133432
-
|
ADC Linker
|
Cancer
|
DBCO-PEG4-SS-TCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-SS-TCO is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-133466
-
|
ADC Linker
|
Cancer
|
Methyltetrazine-PEG4-SS-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-SS-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136035
-
|
ADC Linker
|
Cancer
|
Methyltetrazine-SS-PEG4-Biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-SS-PEG4-Biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136036
-
|
ADC Linker
|
Cancer
|
Tetrazine-SS-PEG4-Biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-SS-PEG4-Biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136078
-
|
ADC Linker
|
Cancer
|
Tetrazine-diazo-PEG4-biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-diazo-PEG4-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-W053709A
-
(4-(1,2,4,5-Tetrazin-3-yl)phenyl)methanamine monohydrochloride; Tetrazine-NH2 monohydrochloride
|
Biochemical Assay Reagents
|
Cancer
|
Tetrazine-Amine monohydrochloride is the monohydrochloride form of Tetrazine-Amine (HY-W053709). Tetrazine-amine is a Tetrazine linker that can be used to covalently label living cells by cycloaddition . Tetrazine-Amine (monohydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-N1839
-
|
Apoptosis
Glucosidase
|
Cancer
|
3-Hydroxybakuchiol can be isolated from Otholobium mexicanum J. W. Grimes. 3-Hydroxybakuchiol is an electron transport chain (ETC) inhibitor. 3-Hydroxybakuchiol has antitumor activity, and induces tumor cell apoptosis. 3-Hydroxybakuchiol also has moderate inhibitory activity against α-glucosidase (IC50: 345 μM) .
|
-
- HY-136406S
-
|
Isotope-Labeled Compounds
|
Cancer
|
Bongkrekic acid-13C28 is the C13 labeled Bongkrekic acid. Bongkrekic acid is a mitochondrial toxin secreted by the bacteria Pseudomonas cocovenenans. Bongkrekic acid specific ligand for mitochondrial adenine nucleotide translocase (ANT) rather than the electron transport chain. Bongkrekic acid has to cross the mitochondrial inner membrane to produce its inhibitory effect on ADP/ATP transport .
|
-
- HY-112053
-
2,2-Diphenyl-1-picrylhydrazyl
|
Others
|
Metabolic Disease
|
DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that can be used to measure the radical scavenging activity of antioxidants. The odd electron of nitrogen atom in DPPH is reduced by receiving a hydrogen atom from antioxidants to the corresponding hydrazine. DPPH method may be utilized in aqueous and nonpolar organic solvents and can be used to examine both hydrophilic and lipophilic antioxidants .
|
-
- HY-130934
-
|
ADC Linker
|
Cancer
|
TCO-PEG1-Val-Cit-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG1-Val-Cit-OH is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-151730
-
|
ADC Linker
|
Others
|
(Me)Tz-butanoic acid is a click chemistry reagent containing an azide. (Me)Tz-butanoic acid is tetrazine linker for conjugation via Diels-Alder-reaction, i.e. copper-free Click reaction with dienophiles . (Me)Tz-butanoic acid is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-155322
-
|
Fluorescent Dye
|
Others
|
Cy3-PEG2-TCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-TCO can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-155323
-
|
Fluorescent Dye
|
Others
|
Cy3-PEG3-TCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-TCO can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-155324
-
|
Fluorescent Dye
|
Others
|
Cy3-PEG7-TCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 7 PEG units. Cy3-PEG7-TCO can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-N1944S
-
|
Fungal
Endogenous Metabolite
Bacterial
Parasite
Isotope-Labeled Compounds
|
Cancer
|
Nerolidol-d4 is deuterated labeled Tenuazonic acid (HY-N6715). Tenuazonic acid, belonging to tetramic acids that are the largest family of natural products, is a putative nonhost-selective mycotoxin isolated from Alternaria alternate . Tenuazonic acid blocks electron transport beyond primary quinone acceptor (QA) by interacting with D1 protein and it is a broad-spectrum and effective photosystem II (PSII) inhibitor .
|
-
- HY-151833
-
|
ADC Linker
|
Others
|
Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent containing an azide group. Methyltetrazine-amido-N-bis(PEG4-acid) is a PEG derivative that contains a methyltetrazine group and two acid groups. This reagent can react with TCO-containing compounds to form a stable covalent bond without the catalysis of Cu or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. PEG linker increases the water solubility of the compound. Reagent grade, for research use only . Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-130966
-
|
ADC Linker
|
Cancer
|
TCO-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG1-Val-Cit-PABC-OH is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-136100
-
|
ADC Linker
|
Cancer
|
TCO-PEG1-Val-Cit-PABC-PNP is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG1-Val-Cit-PABC-PNP is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-145597
-
|
GLUT
|
Metabolic Disease
Cancer
|
KL-11743 is a potent, orally active, and glucose-competitive inhibitor of the class I glucose transporters, with IC50s of 115, 137, 90, and 68 nM for GLUT1, GLUT2, GLUT3, and GLUT4, respectively. KL-11743 specifically blocks glucose metabolism. KL-11743 can synergize with electron transport inhibitors to induce cell death .
|
-
- HY-B0817S
-
|
Parasite
|
Infection
|
Pyridaben-d13 is the deuterium labeled Pyridaben[1]. Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC50 value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function[2][3].
|
-
- HY-156307
-
|
ADC Linker
|
Cancer
|
Me-Tet-PEG3-Maleimide is an ADC Linker containing 3 PEG units. Me-Tet-PEG3-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-156308
-
|
ADC Linker
|
Cancer
|
Me-Tet-PEG4-Maleimide is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-156312
-
|
ADC Linker
|
Cancer
|
Me-Tet-PEG8-Maleimide is an ADC Linker containing 8 PEG units. Me-Tet-PEG8-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-140313
-
|
ADC Linker
|
Cancer
|
Methyltetrazine-DBCO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Methyltetrazine-DBCO also contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136076
-
|
ADC Linker
|
Cancer
|
TCO-PEG3-CH2-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG3-CH2-aldehyde is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-W250154
-
|
Endogenous Metabolite
|
Metabolic Disease
|
β-Nicotinamide adenine dinucleotide reduced dipotassium is an orally active reduced coenzyme. β-Nicotinamide adenine dinucleotide reduced dipotassium is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. β-Nicotinamide adenine dinucleotide reduced dipotassium plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .
|
-
- HY-155325
-
|
Fluorescent Dye
|
Others
|
Cy3-PEG2-TCO4 is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-TCO4 can use its own TCO group to perform the inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-155326
-
|
Fluorescent Dye
|
Others
|
Cy3-PEG3-TCO4 is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-TCO4 can use its own TCO group to perform the inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-135152
-
|
Reactive Oxygen Species
|
Cancer
|
CYPMPO is a spin-trapping reagent. CYPMPO, a cyclic DEPMPO-type nitrone, is evaluated for spin-trapping capabilities toward hydroxyl and superoxide radicals. anti-oxidant and anti-tumor activity .
|
-
- HY-141009
-
|
PROTAC Linkers
|
Cancer
|
N-(Mal-PEG6)-N-bis(PEG7-TCO) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Mal-PEG6)-N-bis(PEG7-TCO) is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-130943
-
|
ADC Linker
|
Cancer
|
Methyltetrazine-PEG4-SS-PEG4-methyltetrazine is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-SS-PEG4-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-130953
-
|
ADC Linker
|
Cancer
|
Mal-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Mal-PEG4-bis-PEG3-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-130970
-
|
ADC Linker
|
Cancer
|
Amino-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Amino-PEG4-bis-PEG3-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-114936
-
AR-054
|
Bacterial
ADC Cytotoxin
Antibiotic
Mitochondrial Metabolism
|
Infection
Neurological Disease
Cancer
|
Piericidin A (AR-054) is a natural mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor. Piericidin A is a potent neurotoxin and inhibits mitochondrial respiration by disrupting the electron transport system through its action on NADH-ubiquinone reductase. Piericidin A is also a potential quorum-sensing inhibitor that suppresses the expression of the virulence genes of Erwinia carotovora subsp. atroseptica (Eca). Piericidin A is an ADC cytotoxin and has anti-bacterial, anticancer, insecticidal activity .
|
-
- HY-130974
-
|
ADC Linker
|
Cancer
|
Ald-Ph-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Ald-Ph-PEG4-bis-PEG3-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-139859
-
|
ADC Linker
|
Cancer
|
APN-PEG36-tetrazine is an analogue of APN-PEG4-tetrazine. APN-PEG4-tetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . APN-PEG36-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-D1598
-
|
Fluorescent Dye
|
Others
|
Sulfo-CY3 tetrazine potassium is a sulfo-Cyanine3 derivative that contains methyltetrazine moiety (Ex=548 nm, Em=563 nm). Sulfo-CY3 tetrazine potassium can be used for the labeling of metabolically engineered cell-surface glycoconjugates . Sulfo-CY3 tetrazine (potassium) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-D0898
-
|
Biochemical Assay Reagents
|
Others
|
2,4-Dichlorobenzenediazonium tetrafluoroborate is an organic compound commonly used in organic synthesis and dye preparation reactions. It can be used as an azotating agent to form azo dyes with other organic substances, and can be used in coatings, pigments and paints and other industries. In addition, the compound is widely used in certain chemical analysis and detection methods, such as in scientific instruments such as electron microscopes and mass spectrometers. Although the compound has no direct medical applications, it plays an important role in chemical research and laboratory studies.
|
-
- HY-101460
-
|
PROTACs
Molecular Glues
Epigenetic Reader Domain
|
Cancer
|
Tz-Thalidomide is a tetrazine tagged Thalidomide (HY-14658) (Ligands for E3 Ligase). Tz-Thalidomide has binding affinity for BRD4, with IC50s of 46.25 μM (BRD4-1) and 62.55 μM (BRD4-2). Tz-Thalidomide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .
|
-
- HY-D1071
-
|
Fluorescent Dye
|
Others
|
DBCO-PEG12-TCO cantains a TCO and a DBCO moiety. TCO group can specifically react with terrahydrazine. DBCO-PEG12-TCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. DBCO-PEG12-TCO also contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-140312
-
|
PROTAC Linkers
|
Cancer
|
Methyltetrazine-PEG12-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG12-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Methyltetrazine-PEG12-DBCO also contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136084
-
|
ADC Linker
|
Cancer
|
Mal-PEG4-(PEG3-DBCO)-(PEG3-TCO) is a cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Mal-PEG4-(PEG3-DBCO)-(PEG3-TCO) is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-B0166S
-
-
- HY-B0166S1
-
L-Ascorbate-13C; Vitamin C-13C
|
Reactive Oxygen Species
Calcium Channel
Apoptosis
Endogenous Metabolite
|
Neurological Disease
Metabolic Disease
Cancer
|
L-Ascorbic acid- 13C is the 13C-labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor[1][2][3]. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells[4].
|
-
- HY-D1557
-
|
Fluorescent Dye
|
Others
|
Cyanine5.5 tetrazine is a far-infrared luminescent dye. Cyanine5.5 tetrazine is a Cyanine5.5 (HY-D0925A) derivative contains a tetrazine moiety. Cyanine5.5 tetrazine can be used for in vivo imaging and low background applications. Cyanine5.5 tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-W014386
-
|
Biochemical Assay Reagents
|
Others
|
9-Ethyl-9H-carbazol-3-amineWith high electron mobility and other favorable electronic properties, the compound is known for its use in organic electronic devices such as organic light-emitting diodes (OLED)and organic solar cells) have been investigated for potential applications. 9-Ethyl-9H-carbazol-3-amineIt can also be used as a starting material for the synthesis of other organic compounds.
|
-
- HY-133428
-
|
ADC Linker
|
Cancer
|
DBCO-PEG3-TCO is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG3-TCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. DBCO-PEG3-TCO also contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-148057
-
|
Drug-Linker Conjugates for ADC
|
Cancer
|
TCO-PEG4-VC-PAB-MMAE is a agent-linker conjugate for ADC. TCO-PEG4-VC-PAB-MMAE contains a cleavable ADC linker (TCO-PEG4-VC-PA) and a potent tubulin inhibitor MMAE (HY-15162) . TCO-PEG4-VC-PAB-MMAE is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-136079
-
|
ADC Linker
|
Cancer
|
Methyltetrazine-PEG4-hydrazone-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-hydrazone-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Methyltetrazine-PEG4-hydrazone-DBCO also contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-138659
-
JF646, Tetrazine
|
Fluorescent Dye
|
Others
|
Janelia Fluor 646, Tetrazine (JF646, Tetrazine) a red fluorescent dye that contains a tetrazine group. JF646, Tetrazine can be used in cellular imaging . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Janelia Fluor? 646, Tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-D1482
-
|
Fluorescent Dye
|
Others
|
Cy5 Tetrazine is a water-soluble, pH-insensitive from pH 4 to pH 10, far-red-fluorescent probe with excitation ideally suited for the 633 nm or 647 nm laser lines. Its absorption and emission spactra are almost identical to those of Alexa Fluor 647, CF 647 Dye, or any other Cyanine5 based fluorescent dyes. Sulfo-Cy5-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-W250179
-
Polyoxyethylene (6) cetyl ether
|
Biochemical Assay Reagents
|
Others
|
Hexaethylene glycol monohexadecyl ether, is a nonionic surfactant belonging to the polyethylene glycol (PEG) ether family. It has a hydrophilic head and a lipophilic tail, which makes it suitable for a wide range of applications. Specifically, Hexaethylene glycol monohexadecyl ether is commonly used in membrane protein research, for solubilization and stabilization of proteins, and for structural analysis techniques such as X-ray crystallography and electron microscopy. Additionally, Hexaethylene glycol monohexadecyl ether is used in a variety of other industrial and research applications, including drug delivery systems, nanotechnology, and diagnostic analysis. Its unique properties make it ideal for facilitating interactions between molecules with different physicochemical properties.
|
-
- HY-149763
-
|
Amyloid-β
|
Neurological Disease
|
Aβ42 agonist-1 (compound 7a) is a small molecule compound that can promote Aβ42 aggregation. Aβ42 agonist-1 can interact with Aβ42 oligomers and pentamers to promote nontoxic aggregate self-assembly and rapid fibril formation. Aβ42 agonist-1 prevents Aβ42-induced cytotoxicity in HT22 hippocampal neuronal cells .
|
-
- HY-149764
-
|
Amyloid-β
|
Neurological Disease
|
Aβ42 agonist-2 (compound 7b) is a small molecule compound that can promote Aβ42 aggregation. Aβ42 agonist-2 can interact with Aβ42 oligomers and pentamers to promote nontoxic aggregate self-assembly and rapid fibril formation. Aβ42 agonist-2 prevents Aβ42-induced cytotoxicity in HT22 hippocampal neuronal cells .
|
-
- HY-140310
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
TCO-PEG4-DBCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. TCO-PEG4-DBCO also contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-154802
-
|
ADC Linker
|
Cancer
|
TCO-GK-PEG4-NHS ester is an ADC Linker, and can be used for synthesis of [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d. [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d binds with high affinity and immunoreactivity to HER2 . TCO-GK-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-145538
-
5'-Deoxyguanylic acid disodium hydrate
|
DNA/RNA Synthesis
|
Others
|
2'-Deoxyguanosine 5'-monophosphate (5'-Deoxyguanylic acid; dGMP) disodium hydrate is an oxidizable target of the photosensitizer pterin (PT) and can be used to evaluate the photosensitizing properties of biopterins (such as Bip, Fop and Cap) . Pterin causes a photosensitive reaction of dGMP under UV-A radiation, causing damage to DNA molecules. There are two main mechanisms for the photosensitive oxidation of purine nucleotides by pterin in vitro: one is the hydrogen abstraction reaction of electron transfer from dGMP to the triplet excited state of pterin (type I mechanism), and the other is the interaction between dGMP and pterin. The reaction produces singlet molecular oxygen (1O2) (Type II mechanism) .
|
-
- HY-151769
-
|
ADC Linker
|
Others
|
TCO-PEG2-Sulfo-NHS ester-EDC Urea is a click chemistry reagent containing an azide group. TCO-PEG2-Sulfo-NHS ester is a PEG linker containing a TCO moiety and a sulfo-NHS ester moiety. The sulfo group makes this molecule soluble in waqueous buffer. This reagent can be used to label antibodies, proteins and other primary amine-containing macromolecules with TCO moiety. Reagent grade, for research use only . TCO-PEG2-Sulfo-NHS ester-EDC Urea is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-W035133
-
5,10,15,20-Tetra-p-tolyl-21H,23H-porphine
|
Biochemical Assay Reagents
|
Others
|
5,10,15,20-Tetrakis(p-tolyl)porphyrin (TTP) is an organic compound belonging to the class of porphyrins, a cyclic molecule composed of four pyrrole rings linked together. TTP is a synthetic porphyrin commonly used as a sensitizer for dye-sensitized solar cells and a catalyst for organic reactions. Due to its unique structure, TTP has a series of interesting properties, including at specific wavelengths and its potential as a catalyst for various chemical reactions. In dye-sensitized solar cells, TTPs help convert sunlight into electricity by absorbing photons and transferring electrons to the semiconductor layer of the device. In organic chemistry, TTP is often used as a catalyst for various organic compounds in reactions such as oxidation and reduction. Its ability to selectively bind certain substrates makes it a useful tool for synthesizing complex molecules and studying their properties.
|
-
-
-
HY-L0118V
-
|
8,085 compounds
|
A unique set of molecules containing mild electrophilic moieties that covalently interact with amino acid residues in the target protein. The diversity of our compounds for covalent drug discovery ranges from natural product-like scaffolds to macrocycles, creating multiple opportunities in hit generation for a selected target.
|
Cat. No. |
Product Name |
Type |
-
- HY-D1509
-
|
Dyes
|
Phenazine ethosulfate is a cationic dye (Ex=390 nm, Em=530 nm) and an electron acceptor that can be used in dye-linked enzyme assays. Phenazine ethosulfate is an intermediate for detecting nitric oxide reducatase (Nors) activity with the presence of ascorbic acid .
|
-
- HY-103311
-
Ammoniated ruthenium oxychloride
|
Dyes
|
Ruthenium red (Ammoniated ruthenium oxychloride) is a polycationic dye widely used for electron microscopy (EM) of cells, tissues and vegetative bacteria. Ruthenium red strongly reacts with phospholipids and fatty acids and binds to acidic mucopolysaccharides. Ruthenium red is a L-type calcium current (ICa) blocker .
|
-
- HY-B0166GL
-
L-Ascorbate (GMP Like); Vitamin C (GMP Like)
|
Fluorescent Dye
|
L-Ascorbic acid (GMP Like) is the GMP Like class L-Ascorbic acid (HY-B0166). L-Ascorbic acid (L-Ascorbate, Vitamin C), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .
|
-
- HY-D1373
-
HBC 530
|
Fluorescent Dyes/Probes
|
HBC is a green fluorescent protein (GFP) fluorophore-like synthetic dye, with a structurally rigid electron acceptor and a strong electron donor. HBC is used to detect RNA localization .
|
-
- HY-149203
-
|
Fluorescent Dyes/Probes
|
MQA-P is a multifunctional near-infrared (NIR) fluorescent probe for simultaneously detecting ONOO -, viscosity, and polarity within mitochondria. MQA-P exhibits a remarkable turn-on response to ONOO - (λem=645 nm) and is highly sensitive to viscosity/polarity in the NIR channel with λem>704 nm. MQA-P exhibits excited-state intramolecular charge transfer (ESICT) feature that is highly polarity-sensitive by engineering N,N-dimethylamino as the electron donor and a quinoline cationic unit as the electron acceptor. MQA-P is used for ferroptosis or cancer diagnosis in vitro and in vivo via dual-channel images .
|
-
- HY-125921
-
|
Dyes
|
WST-3 is a water-soluble tetrazolium dye. In the presence of an electron mediator, WST-3 is reduced to WST-3 formazan by NADH and displays an absorption maxima of 433 nM .
|
-
- HY-D1646
-
|
Fluorescent Dyes/Probes
|
BDP TR methyltetrazine is a BDP dye linker containing a methyltetrazine group. BDP TR methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-D2236
-
|
Fluorescent Dyes/Probes
|
SiR-tetrazine is a Tetrazine modified SiR (silicon rhodamine) fluorescent dye. SiR-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .
|
-
- HY-D2235
-
|
Fluorescent Dyes/Probes
|
SiR-Me-tetrazine is a Tetrazine modified SiR (silicon rhodamine) fluorescent dye. SiR-Me-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-D2243
-
|
Fluorescent Dyes/Probes
|
Cy3.5 tetrazineis a Tetrazine modified Cy3.5 fluorescent dye. SiR-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .
|
-
- HY-D2142
-
|
Fluorescent Dyes/Probes
|
Cy5-PEG2-TCO is a fluorescent dye that reacts with tetrazines. Cy5-PEG2-TCO contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
|
-
- HY-151755
-
|
Fluorescent Dyes/Probes
|
Sulfo-Cy3-Tetrazine is a click chemistry reagent containing an tetrazine group. Sulfo-Cy3-Tetrazine is water soluble cyanine fluorescence dye, which is an inverse electron demand [4+2] cycloaddition that takes place between tetrazine and trans-cyclooctene or other strained olefin.
|
-
- HY-D2118
-
|
Fluorescent Dyes/Probes
|
TAMRA-PEG3-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-D2117
-
|
Fluorescent Dyes/Probes
|
TAMRA-PEG4-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG8-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-D2148
-
|
Fluorescent Dyes/Probes
|
AF 430 tetrazine is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 430 nm and an emission wavelength of 542 nm. AF 430 tetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. To achieve specific coupling of dye labels and biomolecules.
|
-
- HY-155322
-
|
Fluorescent Dyes/Probes
|
Cy3-PEG2-TCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-TCO can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-155323
-
|
Fluorescent Dyes/Probes
|
Cy3-PEG3-TCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-TCO can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-155324
-
|
Fluorescent Dyes/Probes
|
Cy3-PEG7-TCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 7 PEG units. Cy3-PEG7-TCO can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-155325
-
|
Fluorescent Dyes/Probes
|
Cy3-PEG2-TCO4 is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-TCO4 can use its own TCO group to perform the inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-155326
-
|
Fluorescent Dyes/Probes
|
Cy3-PEG3-TCO4 is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-TCO4 can use its own TCO group to perform the inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-D1598
-
|
Fluorescent Dyes/Probes
|
Sulfo-CY3 tetrazine potassium is a sulfo-Cyanine3 derivative that contains methyltetrazine moiety (Ex=548 nm, Em=563 nm). Sulfo-CY3 tetrazine potassium can be used for the labeling of metabolically engineered cell-surface glycoconjugates . Sulfo-CY3 tetrazine (potassium) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-D1071
-
|
Dyes
|
DBCO-PEG12-TCO cantains a TCO and a DBCO moiety. TCO group can specifically react with terrahydrazine. DBCO-PEG12-TCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. DBCO-PEG12-TCO also contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-D1557
-
|
Fluorescent Dyes/Probes
|
Cyanine5.5 tetrazine is a far-infrared luminescent dye. Cyanine5.5 tetrazine is a Cyanine5.5 (HY-D0925A) derivative contains a tetrazine moiety. Cyanine5.5 tetrazine can be used for in vivo imaging and low background applications. Cyanine5.5 tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-138659
-
JF646, Tetrazine
|
Fluorescent Dyes/Probes
|
Janelia Fluor 646, Tetrazine (JF646, Tetrazine) a red fluorescent dye that contains a tetrazine group. JF646, Tetrazine can be used in cellular imaging . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Janelia Fluor? 646, Tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-D1482
-
|
Fluorescent Dyes/Probes
|
Cy5 Tetrazine is a water-soluble, pH-insensitive from pH 4 to pH 10, far-red-fluorescent probe with excitation ideally suited for the 633 nm or 647 nm laser lines. Its absorption and emission spactra are almost identical to those of Alexa Fluor 647, CF 647 Dye, or any other Cyanine5 based fluorescent dyes. Sulfo-Cy5-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
Cat. No. |
Product Name |
Type |
-
- HY-B0166GL
-
L-Ascorbate (GMP Like); Vitamin C (GMP Like)
|
Biochemical Assay Reagents
|
L-Ascorbic acid (GMP Like) is the GMP Like class L-Ascorbic acid (HY-B0166). L-Ascorbic acid (L-Ascorbate, Vitamin C), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .
|
-
- HY-15920
-
INT
2 Publications Verification
Iodonitrotetrazolium chloride; p-Iodonitrotetrazolium Violet
|
Biochemical Assay Reagents
|
INT(Iodonitrotetrazolium chloride) is used in various dehydrogenase colorimetric analysis of the electron acceptor.
|
-
- HY-125857
-
|
Biochemical Assay Reagents
|
Cytochrome C is a multi-functional enzyme involving in life and death decisions of the cell. Cytochrome C is essential in mitochondrial electron transport and intrinsic type II apoptosis .
|
-
- HY-P2996
-
|
Biochemical Assay Reagents
|
NAD(P)H-Nitrate reductase is isolated from Aspergillus niger that catalyses the reduction of nitrate to nitrite via a two-electron transfer. In plants, the electron donor for Nitrate reductase is NADPH is NADH:Nitrate reductase and a bispecific NAD(P)H: Nitrate reductase .
|
-
- HY-W040201
-
3-[3-(Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate
|
Surfactants
|
CHAPSO is a zwitterionic detergent that is thermally stable. CHAPSO is able to broaden the particle orientation distribution, enabling single-particle cryo-electron microscopy (cryo-EM) to produce isotropically uniform maps. CHAPSO can eliminate the directional bias of bacterial transcription complexes and help determine the structure of bacterial transcription complexes under cryo-electron microscopy .
|
-
- HY-D0937
-
1-Methoxy PMS; 1-Methoxyphenazine methosulfate
|
Biochemical Assay Reagents
|
Methoxy-PMS (1-Methoxy PMS), an active oxygen formation inducer, is stable electron-transport mediator between NAD(P)H and tetrazolium dyes .
|
-
- HY-W008865
-
|
Biochemical Assay Reagents
|
PIPES sesquisodium is a pH buffer. PIPES refers to Piperazine N-N’-bis [2 ethanol sulphonic acid, an organic based buffer. PIPES can be used in the preparation of a variety of marine and mammalian tissues for electron microscopic study, with pH range of 6.1-7.5 .
|
-
- HY-W250154
-
|
Biochemical Assay Reagents
|
β-Nicotinamide adenine dinucleotide reduced dipotassium is an orally active reduced coenzyme. β-Nicotinamide adenine dinucleotide reduced dipotassium is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. β-Nicotinamide adenine dinucleotide reduced dipotassium plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .
|
-
- HY-D0898
-
|
Biochemical Assay Reagents
|
2,4-Dichlorobenzenediazonium tetrafluoroborate is an organic compound commonly used in organic synthesis and dye preparation reactions. It can be used as an azotating agent to form azo dyes with other organic substances, and can be used in coatings, pigments and paints and other industries. In addition, the compound is widely used in certain chemical analysis and detection methods, such as in scientific instruments such as electron microscopes and mass spectrometers. Although the compound has no direct medical applications, it plays an important role in chemical research and laboratory studies.
|
-
- HY-W014386
-
|
Biochemical Assay Reagents
|
9-Ethyl-9H-carbazol-3-amineWith high electron mobility and other favorable electronic properties, the compound is known for its use in organic electronic devices such as organic light-emitting diodes (OLED)and organic solar cells) have been investigated for potential applications. 9-Ethyl-9H-carbazol-3-amineIt can also be used as a starting material for the synthesis of other organic compounds.
|
-
- HY-W250179
-
Polyoxyethylene (6) cetyl ether
|
Biochemical Assay Reagents
|
Hexaethylene glycol monohexadecyl ether, is a nonionic surfactant belonging to the polyethylene glycol (PEG) ether family. It has a hydrophilic head and a lipophilic tail, which makes it suitable for a wide range of applications. Specifically, Hexaethylene glycol monohexadecyl ether is commonly used in membrane protein research, for solubilization and stabilization of proteins, and for structural analysis techniques such as X-ray crystallography and electron microscopy. Additionally, Hexaethylene glycol monohexadecyl ether is used in a variety of other industrial and research applications, including drug delivery systems, nanotechnology, and diagnostic analysis. Its unique properties make it ideal for facilitating interactions between molecules with different physicochemical properties.
|
-
- HY-W035133
-
5,10,15,20-Tetra-p-tolyl-21H,23H-porphine
|
Biochemical Assay Reagents
|
5,10,15,20-Tetrakis(p-tolyl)porphyrin (TTP) is an organic compound belonging to the class of porphyrins, a cyclic molecule composed of four pyrrole rings linked together. TTP is a synthetic porphyrin commonly used as a sensitizer for dye-sensitized solar cells and a catalyst for organic reactions. Due to its unique structure, TTP has a series of interesting properties, including at specific wavelengths and its potential as a catalyst for various chemical reactions. In dye-sensitized solar cells, TTPs help convert sunlight into electricity by absorbing photons and transferring electrons to the semiconductor layer of the device. In organic chemistry, TTP is often used as a catalyst for various organic compounds in reactions such as oxidation and reduction. Its ability to selectively bind certain substrates makes it a useful tool for synthesizing complex molecules and studying their properties.
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P2996
-
|
Peptides
|
Others
|
NAD(P)H-Nitrate reductase is isolated from Aspergillus niger that catalyses the reduction of nitrate to nitrite via a two-electron transfer. In plants, the electron donor for Nitrate reductase is NADPH is NADH:Nitrate reductase and a bispecific NAD(P)H: Nitrate reductase .
|
-
- HY-K1063
-
|
MCE Exosome Isolation and Purification Kit provides a simple and effective method to isolate and purify intact exosomes from plasma and serum that can be used for electron microscope analysis, NTA analysis, WB, qPCR, etc.
|
-
- HY-K1062
-
|
MCE Exosome Isolation and Purification Kit provides a simple and effective method to isolate and purify intact exosomes from cell culture media that can be used for electron microscope analysis, NTA analysis, WB, qPCR, etc.
|
-
- HY-K1065
-
|
MCE Exosome Isolation and Purification Kit provides a simple and effective method to isolate and purify intact exosomes from cerebro-spinal fluid, amniotic fluid, milk, saliva, etc, which can be used for electron microscope analysis, NTA analysis, WB, qPCR, etc.
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
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- HY-B0166S8
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L-Ascorbic acid- 13C6-1 (L-Ascorbate-1; Vitamin C- 13C6-1) is a 13C labeled L-Ascorbic acid (HY-B0166) . L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .
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-
- HY-B1849S
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Hexazinone-d6 is the deuterium labeled Hexazinone[1]. Hexazinone is a nonselective herbicide from the triazine family. Hexazinone binds to the D-1 quinone protein of the electron transport chain in photosystem II to inhibit the photosynthesis[2].
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-
- HY-N0111S2
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Coenzyme Q10-d9 is the deuterium labeled Coenzyme Q10. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.
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-
-
- HY-N0111S
-
|
Coenzyme Q10-d6 is deuterium labeled Coenzyme Q10. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.
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-
-
- HY-B0166S6
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|
L-Ascorbic acid-d2 is the deuterium labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a colla
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-
-
- HY-B0849S
-
|
Azoxystrobin-d4 is deuterium labeled Azoxystrobin. Azoxystrobin is a broad-spectrum β-methoxyacrylate fungicide. Azoxystrobin inhibits mitochondrial respiration by binding to the Qo site of the cytochrome bc1 complex and inhibiting electron transfer. Azoxystrobin induces the production of reactive oxygen species (ROS) and induces cell apoptosis.
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-
-
- HY-B0166S2
-
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L-Ascorbic acid- 13C-1 is the 13C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen
|
-
-
- HY-B0166S3
-
|
L-Ascorbic acid- 13C-2 is the 13C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen
|
-
-
- HY-B0166S4
-
|
L-Ascorbic acid- 13C-3 is the 13C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen
|
-
-
- HY-B0166S5
-
|
L-Ascorbic acid- 13C-4 is the 13C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collag
|
-
-
- HY-B0849S1
-
|
Azoxystrobin-d3 is deuterium labeled Azoxystrobin. Azoxystrobin is a broad-spectrum β-methoxyacrylate fungicide. Azoxystrobin inhibits mitochondrial respiration by binding to the Qo site of the cytochrome bc1 complex and inhibiting electron transfer. Azoxystrobin induces the production of reactive oxygen species (ROS) and induces cell apoptosis[1].
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-
-
- HY-136406S
-
|
Bongkrekic acid-13C28 is the C13 labeled Bongkrekic acid. Bongkrekic acid is a mitochondrial toxin secreted by the bacteria Pseudomonas cocovenenans. Bongkrekic acid specific ligand for mitochondrial adenine nucleotide translocase (ANT) rather than the electron transport chain. Bongkrekic acid has to cross the mitochondrial inner membrane to produce its inhibitory effect on ADP/ATP transport .
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-
-
- HY-N1944S
-
|
Nerolidol-d4 is deuterated labeled Tenuazonic acid (HY-N6715). Tenuazonic acid, belonging to tetramic acids that are the largest family of natural products, is a putative nonhost-selective mycotoxin isolated from Alternaria alternate . Tenuazonic acid blocks electron transport beyond primary quinone acceptor (QA) by interacting with D1 protein and it is a broad-spectrum and effective photosystem II (PSII) inhibitor .
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-
-
- HY-B0817S
-
|
Pyridaben-d13 is the deuterium labeled Pyridaben[1]. Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC50 value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function[2][3].
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-
-
- HY-B0166S
-
|
L-Ascorbic acid- 13C6 is the 13C-labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor[1][2][3]. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells[4].
|
-
-
- HY-B0166S1
-
|
L-Ascorbic acid- 13C is the 13C-labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor[1][2][3]. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells[4].
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-
Cat. No. |
Product Name |
|
Classification |
-
- HY-D1646
-
|
|
Tetrazine
Labeling and Fluorescence Imaging
|
BDP TR methyltetrazine is a BDP dye linker containing a methyltetrazine group. BDP TR methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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-
- HY-151698B
-
|
|
TCO
|
(R,E)-TCO-NHS Ester is a Click Amino Acid that can be used to label amine-containing compounds or biomolecules. TCO-NHS ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
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-
- HY-151698A
-
|
|
TCO
|
(S,E)-TCO-NHS Ester is a Click Amino Acid that can be used to label amine-containing compounds or biomolecules. TCO-NHS ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
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-
- HY-D2236
-
|
|
Tetrazine
|
SiR-tetrazine is a Tetrazine modified SiR (silicon rhodamine) fluorescent dye. SiR-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .
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-
- HY-151698
-
|
|
TCO
|
TCO-NHS Ester axial is a click chemistry reagent that can be used as a building block in amine reactions. TCO-NHS Ester axial contains TCO groups, which can undergo inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-D2235
-
|
|
Tetrazine
|
SiR-Me-tetrazine is a Tetrazine modified SiR (silicon rhodamine) fluorescent dye. SiR-Me-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-124480
-
|
|
Tetrazine
PROTAC Synthesis
|
Tetrazine-Ph-acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-acid is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136095
-
|
|
Tetrazine
ADC Synthesis
|
Tetrazine-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136104
-
|
|
Tetrazine
ADC Synthesis
|
Methyltetrazine-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-Maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-24592
-
|
|
TCO
|
(S,E)-Cyclooct-2-enol is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. TCO-NHS ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
|
-
- HY-W784030A
-
|
|
TCO
|
(S,E)-N-TCO-L-lysine is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. (S,E)-N-TCO-L-lysine contains a TCO group and can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
|
-
- HY-W784030B
-
|
|
TCO
|
(R,E)-N-TCO-L-lysine is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. (R,E)-N-TCO-L-lysine contains a TCO group and can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
|
-
- HY-126908
-
|
|
PROTAC Synthesis
Tetrazine
|
Tetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-130283
-
|
|
PROTAC Synthesis
Tetrazine
|
Methyltetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-Ph-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136032
-
|
|
Tetrazine
ADC Synthesis
|
Tetrazine-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136033
-
|
|
Tetrazine
ADC Synthesis
|
Methyltetrazine-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136039
-
|
|
TCO
ADC Synthesis
|
TCO-SS-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-SS-amine is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-130928
-
|
|
Tetrazine
ADC Synthesis
|
Tetrazine-Ph-OPSS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-Ph-OPSS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136031
-
|
|
Tetrazine
ADC Synthesis
|
Tetrazine-SS-Biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-SS-Biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-W053709
-
(4-(1,2,4,5-Tetrazin-3-yl)phenyl)methanamine; Tetrazine-NH2
|
|
Tetrazine
|
Tetrazine-Amine is a tetrazine linker that can be used to covalently label live cells through a cycloaddition . Tetrazine-Amine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-141161B
-
|
|
TCO
|
(R)-TCO-PEG8-acid is an ADC linker containing 8 PEG units. (R)-TCO-PEG8-acid can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-D2243
-
|
|
Tetrazine
|
Cy3.5 tetrazineis a Tetrazine modified Cy3.5 fluorescent dye. SiR-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .
|
-
- HY-133504
-
|
|
ADC Synthesis
Tetrazine
|
Tetrazine-Ph-SS-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-Ph-SS-amine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-141167B
-
|
|
TCO
|
(S)-TCO-PEG4-NHS ester is an ADC linker containing 4 PEG units. (S)-TCO-PEG4-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-141169A
-
|
|
TCO
|
(S)-TCO-PEG8-NHS ester is an ADC linker containing 8 PEG units. (S)-TCO-PEG8-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-157008
-
|
|
TCO
|
(S)-TCO-PEG2-Maleimide is an ADC linker containing 2 PEG units. (S)-TCO-PEG2-Maleimide can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-140015
-
|
|
PROTAC Synthesis
TCO
|
TCO-PEG3-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . TCO-PEG3-acid is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-141286
-
|
|
Tetrazine
PROTAC Synthesis
|
TAMRA-PEG4-methyltetrazine is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-methyltetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-140731
-
|
|
TCO
PROTAC Synthesis
|
TCO-PEG-TCO (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG-TCO (MW 5000) is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-141285
-
|
|
Tetrazine
PROTAC Synthesis
|
TAMRA-PEG4-tetrazine is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-tetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-156313
-
|
|
Tetrazine
|
Me-Tet-PEG4-NHS is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156475
-
|
|
Tetrazine
|
Me-Tet-PEG2-COOH is an ADC Linker containing 2 PEG units. Me-Tet-PEG2-COOH can use its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156476
-
|
|
Tetrazine
|
Me-Tet-PEG2-NHS is an ADC Linker containing 2 PEG units. Me-Tet-PEG2-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156477
-
|
|
Tetrazine
|
Me-Tet-PEG8-NHBoc is an ADC Linker containing 8 PEG units. Me-Tet-PEG8-NHBoc can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156478
-
|
|
Tetrazine
|
Me-Tet-PEG4-NHBoc is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NHBoc can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156479
-
|
|
Tetrazine
|
Me-Tet-PEG3-NHBoc is an ADC Linker containing 3 PEG units. Me-Tet-PEG3-NHBoc can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156490
-
|
|
Tetrazine
|
Me-Tet-PEG5-NHS is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156491
-
|
|
Tetrazine
|
Me-Tet-PEG9-NHS is an ADC Linker containing 9 PEG units. Me-Tet-PEG9-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156492
-
|
|
Tetrazine
|
Me-Tet-PEG4-COOH is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156493
-
|
|
Tetrazine
|
Me-Tet-PEG5-COOH is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156494
-
|
|
Tetrazine
|
Me-Tet-PEG9-COOH is an ADC Linker containing 9 PEG units. Me-Tet-PEG9-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156495
-
|
|
Labeling and Fluorescence Imaging
Tetrazine
|
Biotin-PEG3-Me-Tet is an ADC Linker containing 3 PEG units. Biotin-PEG3-Me-Tet can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-D2142
-
|
|
TCO
Labeling and Fluorescence Imaging
|
Cy5-PEG2-TCO is a fluorescent dye that reacts with tetrazines. Cy5-PEG2-TCO contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
|
-
- HY-151691
-
|
|
Tetrazine
|
Trisulfo-Cy3 Methyltetrazine is a click chemistry reagent containing an methyltetrazine group. Methyltetrazine-activated Cy3 probe reacts with TCO-containing compounds via an Inverse-Electron-Demand Diels-Alder reaction to form a stable covalent bond and does not require Cu-catalyst or elevated temperatures .
|
-
- HY-140940
-
|
|
PROTAC Synthesis
Tetrazine
|
Biotin-PEG4-methyltetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133467
-
|
|
Tetrazine
PROTAC Synthesis
|
Methyltetrazine-PEG5-methyltetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG5-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133468
-
|
|
Tetrazine
PROTAC Synthesis
|
Methyltetrazine-PEG6-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG6-maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133474
-
|
|
TCO
PROTAC Synthesis
|
TCO-PEG3-oxyamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG3-oxyamine is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-133476
-
|
|
TCO
PROTAC Synthesis
|
TCO-PEG3-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG3-alcohol is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-133478
-
|
|
PROTAC Synthesis
TCO
|
TCO-PEG11-TCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG11-TCO is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
- HY-133475
-
|
|
PROTAC Synthesis
TCO
|
TCO-PEG5-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG5-maleimide is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
- HY-133505
-
|
|
PROTAC Synthesis
Tetrazine
|
Methyltetrazine-PEG4-amine (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG4-amine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-133508
-
|
|
Tetrazine
PROTAC Synthesis
|
Methyltetrazine-PEG4-SSPy is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG4-SSPy is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-133497
-
|
|
TCO
PROTAC Synthesis
|
HyNic-PEG2-TCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . HyNic-PEG2-TCO is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
- HY-157003
-
|
|
TCO
|
(S)-TCO-PEG2-NH2 is an ADC Linker containing 2 PEG units. (S)-TCO-PEG2-NH2 can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
- HY-157006
-
|
|
TCO
|
(S)-TCO-PEG3-NH2 is an ADC linker containing 3 PEG units. (S)-TCO-PEG3-NH2 can use its own TCO group to perform the inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
- HY-157007
-
|
|
TCO
|
(S)-TCO-PEG7-NH2 is an ADC linker containing 7 PEG units. (S)-TCO-PEG7-NH2 can use its own TCO group to perform the inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
- HY-D2118
-
|
|
Tetrazine
Labeling and Fluorescence Imaging
|
TAMRA-PEG3-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-D2117
-
|
|
Tetrazine
Labeling and Fluorescence Imaging
|
TAMRA-PEG4-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG8-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-130508
-
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|
PROTAC Synthesis
Azide
Tetrazine
|
Methyltetrazine-Ph-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-Ph-PEG4-azide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-130551
-
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|
Tetrazine
PROTAC Synthesis
|
Tetrazine-Ph-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-PEG5-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-133477
-
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|
TCO
PROTAC Synthesis
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(S)-TCO-PEG3-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . (S)-TCO-PEG3-maleimide is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
- HY-138747
-
|
|
PROTAC Synthesis
Tetrazine
|
Bis-sulfone-PEG4-Tetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bis-sulfone-PEG4-Tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-156300
-
|
|
Tetrazine
|
Me-Tet-PEG4-NH2 is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NH2 can use its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
- HY-156301A
-
|
|
Tetrazine
|
Me-Tet-PEG8-NH2 (hydrochloride) is an ADC Linker containing 2 PEG units. Me-Tet-PEG8-NH2 (hydrochloride) can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
- HY-W591272
-
|
|
Tetrazine
|
Me-Tet-PEG3-NH2 is an ADC Linker containing 3 PEG units. Me-Tet-PEG3-NH2 can use its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
- HY-D2148
-
|
|
Tetrazine
|
AF 430 tetrazine is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 430 nm and an emission wavelength of 542 nm. AF 430 tetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. To achieve specific coupling of dye labels and biomolecules.
|
- HY-140141
-
|
|
PROTAC Synthesis
Tetrazine
|
PC Methyltetrazine-PEG4-NHS carbonate ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . PC Methyltetrazine-PEG4-NHS carbonate ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-133460
-
|
|
PROTAC Synthesis
Tetrazine
|
Tetrazine-Ph-NHCO-PEG3-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHCO-PEG3-alcohol is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-133463
-
|
|
Tetrazine
PROTAC Synthesis
|
Tetrazine-Ph-PEG5-Ph-tetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-PEG5-Ph-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-133465
-
|
|
PROTAC Synthesis
Tetrazine
|
Tetrazine-Ph-PEG4-Ph-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-PEG4-Ph-aldehyde is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-133479
-
|
|
PROTAC Synthesis
Tetrazine
|
Tetrazine-Ph-NHCO-C3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHCO-C3-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-136052
-
|
|
ADC Synthesis
Tetrazine
|
Tetrazine-PEG4-oxyamine (hydrochloride) is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-oxyamine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-136050
-
|
|
ADC Synthesis
TCO
|
TCO-PEG3-Biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG3-Biotin is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
- HY-136053
-
|
|
Tetrazine
ADC Synthesis
|
Tetrazine-PEG4-biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-136056
-
|
|
ADC Synthesis
Tetrazine
|
Methyltetrazine-PEG4-oxyamine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-oxyamine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-136045
-
|
|
Tetrazine
ADC Synthesis
|
APN-PEG4-tetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . APN-PEG4-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-130977
-
|
|
ADC Synthesis
Tetrazine
|
Tetrazine-PEG4-amine (hydrochloride) is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-amine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-136074
-
|
|
Tetrazine
ADC Synthesis
|
Methyltetrazine-PEG4-aldehyde is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-aldehyde is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-136077
-
|
|
ADC Synthesis
TCO
|
TCO-PEG3-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG3-aldehyde is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
- HY-136086
-
|
|
ADC Synthesis
Tetrazine
|
Tetrazine-PEG6-amine (hydrochloride) is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG6-amine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-148211
-
|
|
Tetrazine
|
Tetrazine-PEG7-amine hydrochloride is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG7-amine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-160258
-
GDP-Fucose-Am-Tz
|
|
Tetrazine
|
GDP-Fucose-Tz (GDP-Fucose-Am-Tz) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. GDP-fucose-Am-Tz and TCO-ssDNA were reacted at a ratio of 1:1 to obtain the final product GDP-fucose-ssDNA .
|
- HY-133461
-
|
|
PROTAC Synthesis
Tetrazine
|
Tetrazine-Ph-NHCO-PEG6-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHCO-PEG6-NH-Boc is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-133462
-
|
|
Tetrazine
PROTAC Synthesis
|
Tetrazine-Ph-NHCO-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHCO-PEG4-NH-Boc is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-136040
-
|
|
Tetrazine
ADC Synthesis
|
Tetrazine-PEG4-SS-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-130945
-
|
|
Tetrazine
ADC Synthesis
|
Tetrazine-PEG5-SS-amine is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG5-SS-amine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-130947
-
|
|
ADC Synthesis
Tetrazine
|
Tetrazine-PEG4-SS-Py is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-SS-Py is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-130955
-
|
|
TCO
ADC Synthesis
|
Amino-bis-PEG3-TCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Amino-bis-PEG3-TCO is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
- HY-133432
-
|
|
TCO
ADC Synthesis
DBCO
|
DBCO-PEG4-SS-TCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-SS-TCO is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
- HY-133466
-
|
|
ADC Synthesis
Tetrazine
|
Methyltetrazine-PEG4-SS-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-SS-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-136035
-
|
|
ADC Synthesis
Tetrazine
|
Methyltetrazine-SS-PEG4-Biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-SS-PEG4-Biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-136036
-
|
|
ADC Synthesis
Tetrazine
|
Tetrazine-SS-PEG4-Biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-SS-PEG4-Biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-136078
-
|
|
ADC Synthesis
Tetrazine
|
Tetrazine-diazo-PEG4-biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-diazo-PEG4-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-W053709A
-
(4-(1,2,4,5-Tetrazin-3-yl)phenyl)methanamine monohydrochloride; Tetrazine-NH2 monohydrochloride
|
|
Tetrazine
|
Tetrazine-Amine monohydrochloride is the monohydrochloride form of Tetrazine-Amine (HY-W053709). Tetrazine-amine is a Tetrazine linker that can be used to covalently label living cells by cycloaddition . Tetrazine-Amine (monohydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-130934
-
|
|
ADC Synthesis
TCO
|
TCO-PEG1-Val-Cit-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG1-Val-Cit-OH is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
- HY-151730
-
|
|
Tetrazine
|
(Me)Tz-butanoic acid is a click chemistry reagent containing an azide. (Me)Tz-butanoic acid is tetrazine linker for conjugation via Diels-Alder-reaction, i.e. copper-free Click reaction with dienophiles . (Me)Tz-butanoic acid is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-155322
-
|
|
TCO
Labeling and Fluorescence Imaging
|
Cy3-PEG2-TCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-TCO can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
- HY-155323
-
|
|
Labeling and Fluorescence Imaging
TCO
|
Cy3-PEG3-TCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-TCO can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
- HY-155324
-
|
|
Labeling and Fluorescence Imaging
TCO
|
Cy3-PEG7-TCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 7 PEG units. Cy3-PEG7-TCO can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
- HY-151833
-
|
|
Tetrazine
|
Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent containing an azide group. Methyltetrazine-amido-N-bis(PEG4-acid) is a PEG derivative that contains a methyltetrazine group and two acid groups. This reagent can react with TCO-containing compounds to form a stable covalent bond without the catalysis of Cu or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. PEG linker increases the water solubility of the compound. Reagent grade, for research use only . Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-130966
-
|
|
ADC Synthesis
TCO
|
TCO-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG1-Val-Cit-PABC-OH is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
- HY-136100
-
|
|
ADC Synthesis
TCO
|
TCO-PEG1-Val-Cit-PABC-PNP is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG1-Val-Cit-PABC-PNP is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
- HY-156307
-
|
|
Tetrazine
|
Me-Tet-PEG3-Maleimide is an ADC Linker containing 3 PEG units. Me-Tet-PEG3-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
- HY-156308
-
|
|
Tetrazine
|
Me-Tet-PEG4-Maleimide is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
- HY-156312
-
|
|
Tetrazine
|
Me-Tet-PEG8-Maleimide is an ADC Linker containing 8 PEG units. Me-Tet-PEG8-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
- HY-140313
-
|
|
DBCO
Tetrazine
ADC Synthesis
|
Methyltetrazine-DBCO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Methyltetrazine-DBCO also contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-136076
-
|
|
TCO
ADC Synthesis
|
TCO-PEG3-CH2-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG3-CH2-aldehyde is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
- HY-155325
-
|
|
Labeling and Fluorescence Imaging
TCO
|
Cy3-PEG2-TCO4 is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-TCO4 can use its own TCO group to perform the inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
- HY-155326
-
|
|
TCO
Labeling and Fluorescence Imaging
|
Cy3-PEG3-TCO4 is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-TCO4 can use its own TCO group to perform the inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
- HY-141009
-
|
|
PROTAC Synthesis
TCO
|
N-(Mal-PEG6)-N-bis(PEG7-TCO) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Mal-PEG6)-N-bis(PEG7-TCO) is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
- HY-130943
-
|
|
Tetrazine
ADC Synthesis
|
Methyltetrazine-PEG4-SS-PEG4-methyltetrazine is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-SS-PEG4-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-130953
-
|
|
ADC Synthesis
Tetrazine
|
Mal-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Mal-PEG4-bis-PEG3-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-130970
-
|
|
Tetrazine
ADC Synthesis
|
Amino-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Amino-PEG4-bis-PEG3-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-130974
-
|
|
ADC Synthesis
Tetrazine
|
Ald-Ph-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Ald-Ph-PEG4-bis-PEG3-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-139859
-
|
|
ADC Synthesis
Tetrazine
|
APN-PEG36-tetrazine is an analogue of APN-PEG4-tetrazine. APN-PEG4-tetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . APN-PEG36-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-D1598
-
|
|
Tetrazine
Labeling and Fluorescence Imaging
|
Sulfo-CY3 tetrazine potassium is a sulfo-Cyanine3 derivative that contains methyltetrazine moiety (Ex=548 nm, Em=563 nm). Sulfo-CY3 tetrazine potassium can be used for the labeling of metabolically engineered cell-surface glycoconjugates . Sulfo-CY3 tetrazine (potassium) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-101460
-
|
|
Tetrazine
|
Tz-Thalidomide is a tetrazine tagged Thalidomide (HY-14658) (Ligands for E3 Ligase). Tz-Thalidomide has binding affinity for BRD4, with IC50s of 46.25 μM (BRD4-1) and 62.55 μM (BRD4-2). Tz-Thalidomide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .
|
- HY-D1071
-
|
|
DBCO
|
DBCO-PEG12-TCO cantains a TCO and a DBCO moiety. TCO group can specifically react with terrahydrazine. DBCO-PEG12-TCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. DBCO-PEG12-TCO also contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
- HY-140312
-
|
|
PROTAC Synthesis
DBCO
Tetrazine
|
Methyltetrazine-PEG12-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG12-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Methyltetrazine-PEG12-DBCO also contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-136084
-
|
|
ADC Synthesis
TCO
|
Mal-PEG4-(PEG3-DBCO)-(PEG3-TCO) is a cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Mal-PEG4-(PEG3-DBCO)-(PEG3-TCO) is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
- HY-D1557
-
|
|
Tetrazine
Labeling and Fluorescence Imaging
|
Cyanine5.5 tetrazine is a far-infrared luminescent dye. Cyanine5.5 tetrazine is a Cyanine5.5 (HY-D0925A) derivative contains a tetrazine moiety. Cyanine5.5 tetrazine can be used for in vivo imaging and low background applications. Cyanine5.5 tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-133428
-
|
|
TCO
ADC Synthesis
DBCO
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DBCO-PEG3-TCO is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG3-TCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. DBCO-PEG3-TCO also contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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- HY-148057
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TCO
ADC Synthesis
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TCO-PEG4-VC-PAB-MMAE is a agent-linker conjugate for ADC. TCO-PEG4-VC-PAB-MMAE contains a cleavable ADC linker (TCO-PEG4-VC-PA) and a potent tubulin inhibitor MMAE (HY-15162) . TCO-PEG4-VC-PAB-MMAE is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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- HY-136079
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ADC Synthesis
Tetrazine
DBCO
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Methyltetrazine-PEG4-hydrazone-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-hydrazone-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Methyltetrazine-PEG4-hydrazone-DBCO also contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-138659
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JF646, Tetrazine
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Tetrazine
Labeling and Fluorescence Imaging
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Janelia Fluor 646, Tetrazine (JF646, Tetrazine) a red fluorescent dye that contains a tetrazine group. JF646, Tetrazine can be used in cellular imaging . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Janelia Fluor? 646, Tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-D1482
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Labeling and Fluorescence Imaging
Tetrazine
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Cy5 Tetrazine is a water-soluble, pH-insensitive from pH 4 to pH 10, far-red-fluorescent probe with excitation ideally suited for the 633 nm or 647 nm laser lines. Its absorption and emission spactra are almost identical to those of Alexa Fluor 647, CF 647 Dye, or any other Cyanine5 based fluorescent dyes. Sulfo-Cy5-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-140310
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PROTAC Synthesis
TCO
DBCO
ADC Synthesis
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TCO-PEG4-DBCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. TCO-PEG4-DBCO also contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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- HY-154802
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TCO
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TCO-GK-PEG4-NHS ester is an ADC Linker, and can be used for synthesis of [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d. [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d binds with high affinity and immunoreactivity to HER2 . TCO-GK-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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- HY-151769
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Labeling and Fluorescence Imaging
TCO
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TCO-PEG2-Sulfo-NHS ester-EDC Urea is a click chemistry reagent containing an azide group. TCO-PEG2-Sulfo-NHS ester is a PEG linker containing a TCO moiety and a sulfo-NHS ester moiety. The sulfo group makes this molecule soluble in waqueous buffer. This reagent can be used to label antibodies, proteins and other primary amine-containing macromolecules with TCO moiety. Reagent grade, for research use only . TCO-PEG2-Sulfo-NHS ester-EDC Urea is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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