fatty acid derivative

By Targets:	FATP (1) Bacterial (1) Biochemical Assay Reagents (3) COX (1) Cytochrome P450 (1) Endogenous Metabolite (3) Fluorescent Dye (3) Liposome (1) NF-κB (1)
By Research Areas:	Cancer (2) Infection (1) Inflammation/Immunology (4) Metabolic Disease (8)
Click Chemistry:	Alkynes (1)

Targets Recommended: Free Fatty Acid Receptor Fatty Acid Synthase (FASN) FATP FABP FAAH ELOVL Amino Acid Derivatives Hydroxycarboxylic Acid Receptor (HCAR) Apical Sodium-Dependent Bile Acid Transporter G protein-coupled Bile Acid Receptor 1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-126172

9-Anthryldiazomethane

Fluorescent Dye Cancer

9-Anthryldiazomethane is a fluorescent labeling reagent, which can be used for detecting fatty acids and derivatives .

9-Anthryldiazomethane	Fluorescent Dye	Cancer
9-Anthryldiazomethane is a fluorescent labeling reagent, which can be used for detecting fatty acids and derivatives .

HY-141700

FATP1-IN-2 2 Publications Verification	FATP	Metabolic Disease
FATP1-IN-2 (compound 12a), an arylpiperazine derivative, is an orally active fatty acid transport protein 1 (FATP1) inhibitor (human IC₅₀=0.43 μM, mouse IC₅₀=0.39 μM) .

HY-119647

PPOH	COX Cytochrome P450	Others
PPOH, a fatty acid derivative, is a selective cyclooxygenase (COX) inhibitor that inhibits arachidonic acid cyclooxygenase activity in renal cortical microsomes. In addition, PPOH acts on CYP4A2 and CYP4A3 with the IC₅₀ values of 22 μM and 6.5 μM, respectively . PPOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W015881

Dimebutic acid

NSC-16045; NSC-741804
Others Others

Dimebutic acid is a fatty acid derivative .

Dimebutic acid NSC-16045; NSC-741804	Others	Others
Dimebutic acid is a fatty acid derivative .

HY-113434B

5-HETE (±)-5-HETE	Endogenous Metabolite	Inflammation/Immunology
5-HETE ((±)-5-HETE), a fatty acid, is a oxidative derivative of Arachidonic acid. 5-HETE is a mixture of 5(S)-HETE and 5(R)-HETE. 5-HETE is a potent aggregating agent that induces the aggregation of neutrophils with an IC₅₀ value of 200 nM .

HY-N2644

4-Oxododecanedioic acid

Others Others

4-Oxododecanedioic acid is a fatty acid derivative .
HY-145503

Decanoyl-L-carnitine chloride

Others Metabolic Disease

Decanoyl-L-carnitine chloride is an ester derivative of L-carnitine, which is an important cofactor of fatty acid metabolism .
HY-E70274

17:1(n7) Coenzyme A triammonium

Others Metabolic Disease

17:1(n7) Coenzyme A triammonium is a derivative of fatty acyl-CoA .

4-Oxododecanedioic acid	Others	Others
4-Oxododecanedioic acid is a fatty acid derivative .

Decanoyl-L-carnitine chloride	Others	Metabolic Disease
Decanoyl-L-carnitine chloride is an ester derivative of L-carnitine, which is an important cofactor of fatty acid metabolism .

17:1(n7) Coenzyme A triammonium	Others	Metabolic Disease
17:1(n7) Coenzyme A triammonium is a derivative of fatty acyl-CoA .

HY-101722

Melinamide AC 223; DL-N-(α-Methylbenzyl)linoleamide	Others	Metabolic Disease
Melinamide, an amide derivative of an unsaturated long-chain fatty acid, is an inhibitor of cholesterol absorption with an IC₅₀ of 20.9 μM.

HY-E70269

(11Z-Octadecenoyl)-CoA triammonium

Biochemical Assay Reagents Others

(11Z-Octadecenoyl)-CoA triammonium is a derivative of Monounsaturated fatty acid oleic acid (18:1 n7) CoA.

(11Z-Octadecenoyl)-CoA triammonium	Biochemical Assay Reagents	Others
(11Z-Octadecenoyl)-CoA triammonium is a derivative of Monounsaturated fatty acid oleic acid (18:1 n7) CoA.

HY-130405

PtdIns-(1,2-dipalmitoyl) (ammonium)	Others	Metabolic Disease
PtdIns-(1,2-dipalmitoyl) ammonium (DPPI) is a derivative of phosphatidylinositol (PtdIns) that contains C16:0 fatty acyl chains .

HY-134136

Octanoyl Coenzyme A	Endogenous Metabolite	Metabolic Disease
Octanoyl coenzyme A is a fatty acyl coenzyme A derivative. Octanoyl coenzyme A can inhibit citrate synthase (CS) and glutamate dehydrogenase (GDH) with IC₅₀ values of 0.4-1.6 mM .

HY-134136A

Octanoyl coenzyme A lithium	Biochemical Assay Reagents	Cancer
Octanoyl coenzyme A lithium is a fatty acyl coenzyme A derivative. Octanoyl coenzyme A lithium can inhibit citrate synthase (CS) and glutamate dehydrogenase (GDH) with IC₅₀ values of 0.4-1.6 mM .

HY-135808

BIZ 114	NF-κB	Inflammation/Immunology
BIZ 114 (Example 11) is a fatty acid derivative and potent inhibits the TNF-α activated NF-κΒ pathway. BIZ 114 has the potential to prevent and / or treat ophthalmic disorders such as retinal degenerative disorders and ocular inflammatory diseases .

HY-E70267

22:0 Coenzyme A triammonium	Biochemical Assay Reagents	Metabolic Disease
22:0 Coenzyme A triammonium is a derivative of coenzyme A (CoA), where CoA is combined with a 22-carbon saturated fatty acid (behenic acid, also known as docosanoic acid). 22:0 Coenzyme A triammonium can serve as a substrate for AmFAR1 .

HY-D0133

NBD-X acid	Fluorescent Dye	Others
NBD-X acid is a fluorescent probe for the study of fatty acids and sterols. NBD-X acid provides better yields for labelling biopolymers compared to NBD chloride and fluoride. The fluorescence spectrum of the NBD derivative is highly sensitive to the environment and the fluorescence intensity is significantly reduced in aqueous solutions .

HY-W127378

DOTAP methylsulfate 1,2-Dioleoyl-3-trimethylammonium-propane methylsulfate	Liposome	Others
DOTAP Transfection Reagent is a cationic derivative of trimethylammonium attached to two 18-carbon fatty acid tails, each with a single alkene group. 18:1 TAP is a cationic liposome-forming compound useful for the transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells.

HY-121705

Propionyl-L-carnitine	Endogenous Metabolite	Inflammation/Immunology
Propionyl-L-carnitine is a carnitine derivative and has a high affinity for muscular carnitine transferase. Propionyl-L-carnitine increases cellular carnitine content, thereby allowing free fatty acid transport into the mitochondria. Propionyl-L-carnitine alleviates the symptoms of PAD through a metabolic pathway, thereby improving exercise performance .

HY-D1336

FAM amine, 6-isomer	Fluorescent Dye
FAM amine, 6-isomer is a fluorescein derivative with an amine group and contains an isomer of the fluorophore. Can be used to modify biomolecules through enzymatic transamination. Its fatty amine groups can also react with electrophiles such as activated esters. The amine can also be conjugated to carbonyl compounds (aldehydes and ketones) by reductive amination.

HY-121212

Icosabutate	Others	Metabolic Disease Inflammation/Immunology
Icosabutate, an orally active ω-3 polyunsaturated fatty acid, is an aeicosapentaenoic acid (EPA) derivative. Icosabutate overcomes the drawbacks of unmodified EPA for liver targeting and improves insulin sensitivity, hepatic inflammation and fibrosis . Icosabutate is well tolerated, and efficacious in lowering non-high-density lipoprotein cholesterol (non-HDL-C) levels in persistent hypertriglyceridemia .

HY-122643

NITD-916	Bacterial	Infection
NITD-916, a 4-hydroxy-2-pyridone derivative, is an orally active and highly lipophilic mycobacterial enoyl reductase InhA inhibitor with an IC₅₀ of 570 nM. NITD-916 forms a ternary complex with InhA and NADH to block access to the fatty acyl substrate binding pocket. NITD-916 has potent anti-tuberculosis effects .

Cat. No.	Product Name	Type

HY-126172

9-Anthryldiazomethane

Fluorescent Dyes/Probes

9-Anthryldiazomethane is a fluorescent labeling reagent, which can be used for detecting fatty acids and derivatives .

9-Anthryldiazomethane	Fluorescent Dyes/Probes
9-Anthryldiazomethane is a fluorescent labeling reagent, which can be used for detecting fatty acids and derivatives .

HY-D0133

NBD-X acid	Fluorescent Dyes/Probes
NBD-X acid is a fluorescent probe for the study of fatty acids and sterols. NBD-X acid provides better yields for labelling biopolymers compared to NBD chloride and fluoride. The fluorescence spectrum of the NBD derivative is highly sensitive to the environment and the fluorescence intensity is significantly reduced in aqueous solutions .

HY-D1336

FAM amine, 6-isomer	Fluorescent Dyes/Probes
FAM amine, 6-isomer is a fluorescein derivative with an amine group and contains an isomer of the fluorophore. Can be used to modify biomolecules through enzymatic transamination. Its fatty amine groups can also react with electrophiles such as activated esters. The amine can also be conjugated to carbonyl compounds (aldehydes and ketones) by reductive amination.

Cat. No.	Product Name	Type

HY-134136A

Octanoyl coenzyme A lithium	Biochemical Assay Reagents
Octanoyl coenzyme A lithium is a fatty acyl coenzyme A derivative. Octanoyl coenzyme A lithium can inhibit citrate synthase (CS) and glutamate dehydrogenase (GDH) with IC₅₀ values of 0.4-1.6 mM .

HY-W127378

DOTAP methylsulfate 1,2-Dioleoyl-3-trimethylammonium-propane methylsulfate	Drug Delivery
DOTAP Transfection Reagent is a cationic derivative of trimethylammonium attached to two 18-carbon fatty acid tails, each with a single alkene group. 18:1 TAP is a cationic liposome-forming compound useful for the transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells.

HY-134136

Octanoyl Coenzyme A	Biochemical Assay Reagents
Octanoyl coenzyme A is a fatty acyl coenzyme A derivative. Octanoyl coenzyme A can inhibit citrate synthase (CS) and glutamate dehydrogenase (GDH) with IC₅₀ values of 0.4-1.6 mM .

Cat. No.	Product Name	Target	Research Area

HY-121705

Propionyl-L-carnitine	Endogenous Metabolite	Inflammation/Immunology
Propionyl-L-carnitine is a carnitine derivative and has a high affinity for muscular carnitine transferase. Propionyl-L-carnitine increases cellular carnitine content, thereby allowing free fatty acid transport into the mitochondria. Propionyl-L-carnitine alleviates the symptoms of PAD through a metabolic pathway, thereby improving exercise performance .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-121705

Propionyl-L-carnitine	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
Propionyl-L-carnitine is a carnitine derivative and has a high affinity for muscular carnitine transferase. Propionyl-L-carnitine increases cellular carnitine content, thereby allowing free fatty acid transport into the mitochondria. Propionyl-L-carnitine alleviates the symptoms of PAD through a metabolic pathway, thereby improving exercise performance .

HY-113434B

5-HETE (±)-5-HETE	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
5-HETE ((±)-5-HETE), a fatty acid, is a oxidative derivative of Arachidonic acid. 5-HETE is a mixture of 5(S)-HETE and 5(R)-HETE. 5-HETE is a potent aggregating agent that induces the aggregation of neutrophils with an IC₅₀ value of 200 nM .

HY-N2644

4-Oxododecanedioic acid	Structural Classification Ketones, Aldehydes, Acids Source classification Pteridaceae Coniogramme japonica (Thunb.) Diels Plants	Others
4-Oxododecanedioic acid is a fatty acid derivative .

HY-134136

Octanoyl Coenzyme A	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Octanoyl coenzyme A is a fatty acyl coenzyme A derivative. Octanoyl coenzyme A can inhibit citrate synthase (CS) and glutamate dehydrogenase (GDH) with IC₅₀ values of 0.4-1.6 mM .

Cat. No.	Product Name		Classification

HY-119647

PPOH		Alkynes
PPOH, a fatty acid derivative, is a selective cyclooxygenase (COX) inhibitor that inhibits arachidonic acid cyclooxygenase activity in renal cortical microsomes. In addition, PPOH acts on CYP4A2 and CYP4A3 with the IC₅₀ values of 22 μM and 6.5 μM, respectively . PPOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Click Chemistry

fatty acid derivative

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

NaturalProducts

Click Chemistry

Natural
Products