Search Result

Results for "

hepatoprotective

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) AMPK (2) Amyloid-β (3) Antibiotic (1) Apoptosis (21) Aryl Hydrocarbon Receptor (1) Autophagy (12) Bacterial (11) Calcium Channel (1) CDK (1) Chloride Channel (1) COX (6) Cytochrome P450 (2) Dipeptidyl Peptidase (1) DNA/RNA Synthesis (1) DYRK (1) Endogenous Metabolite (12) ERK (3) Fungal (2) Glucosidase (1) GLUT (2) HBV (1) HDAC (1) HIF/HIF Prolyl-Hydroxylase (1) HIV (1) HMG-CoA Reductase (HMGCR) (3) iGluR (1) Influenza Virus (2) Integrin (1) Isotope-Labeled Compounds (6) Keap1-Nrf2 (2) Mitophagy (3) Monoamine Oxidase (1) Necroptosis (1) NF-κB (6) NOD-like Receptor (NLR) (2) Notch (1) Oxidative Phosphorylation (1) Parasite (1) PGE synthase (1) PI3K (1) PPAR (2) Prostaglandin Receptor (1) Proteasome (1) Reactive Oxygen Species (5) Reverse Transcriptase (1) ROS Kinase (1) STAT (1) Topoisomerase (1) Tyrosinase (1) VEGFR (1) Virus Protease (1)
By Research Areas:	Cancer (43) Cardiovascular Disease (10) Endocrinology (1) Infection (20) Inflammation/Immunology (43) Metabolic Disease (33) Neurological Disease (19)

By Targets:

Akt (1)

AMPK (2)

Amyloid-β (3)

Antibiotic (1)

Apoptosis (21)

Aryl Hydrocarbon Receptor (1)

Autophagy (12)

Bacterial (11)

Calcium Channel (1)

CDK (1)

Chloride Channel (1)

COX (6)

Cytochrome P450 (2)

Dipeptidyl Peptidase (1)

DNA/RNA Synthesis (1)

DYRK (1)

Endogenous Metabolite (12)

ERK (3)

Fungal (2)

Glucosidase (1)

GLUT (2)

HBV (1)

HDAC (1)

HIF/HIF Prolyl-Hydroxylase (1)

HIV (1)

HMG-CoA Reductase (HMGCR) (3)

iGluR (1)

Influenza Virus (2)

Integrin (1)

Isotope-Labeled Compounds (6)

Keap1-Nrf2 (2)

Mitophagy (3)

Monoamine Oxidase (1)

Necroptosis (1)

NF-κB (6)

NOD-like Receptor (NLR) (2)

Notch (1)

Oxidative Phosphorylation (1)

Parasite (1)

PGE synthase (1)

PI3K (1)

PPAR (2)

Prostaglandin Receptor (1)

Proteasome (1)

Reactive Oxygen Species (5)

Reverse Transcriptase (1)

ROS Kinase (1)

STAT (1)

Topoisomerase (1)

Tyrosinase (1)

VEGFR (1)

Virus Protease (1)

By Research Areas:

Cancer (43)

Cardiovascular Disease (10)

Endocrinology (1)

Infection (20)

Inflammation/Immunology (43)

Metabolic Disease (33)

Neurological Disease (19)

113

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W027126

Hepatoprotective agent-2	Apoptosis	Metabolic Disease
Hepatoprotective agent-2 (compound 2a), a 4-phenyl-tetrahydroquinoline derivative, displays a remarkable hepatoprotective effect. Hepatoprotective agent-2 has antiapoptotic activity. Hepatoprotective agent-2 notably prevents the chemically induced elevation of hepatic indicators associated with liver injury .

HY-162137

Hepatoprotective agent-1	Apoptosis	Inflammation/Immunology
Hepatoprotective agent-1 (compound 1b) is a hepatoprotective agenrt. Hepatoprotective agent-1 shows anti-inflammatory, antiapoptotic and antifibrotic effects .

HY-N11660

*weak Hepatoprotective* agent-1**	Others	Metabolic Disease
weak Hepatoprotective agent-1 (Compound 11) is a natural product that can be isolated from the fruits of Arctium lappa L.. weak Hepatoprotective agent-1 exhibits weak hepatoprotective activities at a concentration of 10 μM .

HY-N11448

Bupleuroside XIII

Others Metabolic Disease

Bupleuroside XIII is a natural hepatoprotective saponin .
HY-N11563

Potentillanoside A

Others Others

Potentillanoside A is a natural compound with hepatoprotective effect .

Bupleuroside XIII	Others	Metabolic Disease
Bupleuroside XIII is a natural hepatoprotective saponin .

Potentillanoside A	Others	Others
Potentillanoside A is a natural compound with hepatoprotective effect .

HY-114974

Rivenprost ONO-4819; ONO-AE1-734	Prostaglandin Receptor	Others Inflammation/Immunology
Rivenprost (ONO-4819; ONO-AE1-734) is a selective agonist for prostaglandin E receptor EP4 with K_i of 0.7 nM. Rivenprost exhibits hepatoprotective and bone anabolic effects .

HY-N5092

7-Methylcoumarin

Others Metabolic Disease

7-Methylcoumarin, a coumarin, exhibits strong hepatoprotective activity and potent antioxidant effect .

7-Methylcoumarin	Others	Metabolic Disease
7-Methylcoumarin, a coumarin, exhibits strong hepatoprotective activity and potent antioxidant effect .

HY-N2412

Irisolidone	Chloride Channel	Neurological Disease Cancer
Irisolidone is a major isoflavone found in Pueraria lobata flowers. Irisolidone exhibits potent hepatoprotective activity. Irisolidone shows the high efficacy for volume-regulated anion channels (VRAC) blockade (IC₅₀=9.8 μM) .

HY-N0975

1,11b-Dihydro-11b-hydroxymaackiain	Others	Metabolic Disease
1,11b-Dihydro-11b-hydroxymaackiain, a pterocarpane extract from the stems of Erycibe expansa, show a hepatoprotective effect .

HY-N4107

Phyllanthin	Others	Metabolic Disease
Phyllanthin is a major bioactive lignan component of Phyllanthus amarus. Phyllanthin exhibits high antioxidative and hepatoprotective properties .

HY-115363

Curcumenone	Others	Cardiovascular Disease Metabolic Disease
Curcumenone is a major constituent of the plants of medicinally important genus of Curcuma. Curcumenone, a caraborane type sesquiterpene has been reported to be a vasorelaxant, hepatoprotective and an effective inhibitor of intoxication .

HY-106947

SY-640	Endogenous Metabolite	Metabolic Disease
SY-640 is an Acetamide derivative and has potent hepatoprotective effect. SY-640 reduces Propionibacterium acnes and Lipopolysaccharide-induced liver injury in mice .

HY-N10436

Anti-inflammatory agent 30

Others Metabolic Disease Inflammation/Immunology

Anti-inflammatory agent 30 (Compound 5) is an anti-inflammatory agent with hepatoprotective activity .
HY-N10434

Anti-inflammatory agent 28

Others Metabolic Disease Inflammation/Immunology

Anti-inflammatory agent 28 (Compound 9) is an anti-inflammatory agent with hepatoprotective activity .
HY-N10435

Anti-inflammatory agent 29

Others Metabolic Disease Inflammation/Immunology

Anti-inflammatory agent 29 (Compound 7) is an anti-inflammatory agent with hepatoprotective activity .

Anti-inflammatory agent 30	Others	Metabolic Disease Inflammation/Immunology
Anti-inflammatory agent 30 (Compound 5) is an anti-inflammatory agent with hepatoprotective activity .

Anti-inflammatory agent 28	Others	Metabolic Disease Inflammation/Immunology
Anti-inflammatory agent 28 (Compound 9) is an anti-inflammatory agent with hepatoprotective activity .

Anti-inflammatory agent 29	Others	Metabolic Disease Inflammation/Immunology
Anti-inflammatory agent 29 (Compound 7) is an anti-inflammatory agent with hepatoprotective activity .

HY-N10380

Inonotusol F	Others	Metabolic Disease
Inonotusol F is a triterpene isolated from Inonotus obliquus. Inonotusol F shows hepatoprotective effects against D-galactosamine-induced WB-F344 cell damage .

HY-N7543

Schisantherin D	HIV	Infection
Schisantherin D is a dibenzocyclooctadiene lignan isolated from the fruit of Schisandra sphenanthera. Schisantherin D shows anti-HIV replication activities with an EC₅₀ of 0.5 μg/mL. Schisantherin D inhibits endothelin receptor B (ETBR) and has hepatoprotective effects .

HY-N5083

Saponarin 1 Publications Verification	Others	Inflammation/Immunology
Saponarin is a natural flavonoid isolated from Gypsophila trichotoma, with antioxidant, anti-inflammatory and hepatoprotective activities. Saponarin activates AMPK in a calcium-dependent manner, thus regulating gluconeogenesis and glucose uptake .

HY-125129

Carlinoside	Keap1-Nrf2	Others
Carlinoside is a flavone glycoside with hepatoprotective efficiency. Carlinoside reduces hepatic bilirubin accumulation by stimulating bilirubin-UGT activity through Nrf2 gene expression. Carlinoside has the potential to intervene hyperbilirubinemia due to liver dysfunction .

HY-N1521

Rehmannic acid Lantadene A	Others	Inflammation/Immunology
Rehmannic acid (lantadene A) is a compound isolated from Lantana camara. Rehmannic acid shows considerable in vitro antioxidant, free radical scavenging capacity activities in a dose dependant manner. Rehmannic acid is a promising candidate for use as an antioxidant and hepatoprotective agent .

HY-N12072

3'-Methoxy-3,5,4'-trihydroxyflavone-7-neohesperidoside	Others	Others
3'-Methoxy-3,5,4'-trihydroxyflavone-7-neohesperidoside is a flavonoid that can be isolated from Cleome droserifolia. 3'-Methoxy-3,5,4'-trihydroxyflavone-7-neohesperidoside has moderate hepatoprotective activity ..

HY-145888

Antioxidant agent-2	Amyloid-β	Neurological Disease
Antioxidant agent-2 (comp 3c), an BBB-penetrated antioxidant agent and a selective metal ions chelator, presents good neuroprotective effect and hepatoprotective effect for the study of Alzheimer’s disease .

HY-N1214S

Squalene-d6 Super Squalene-d₆; trans-Squalene-d₆; AddaVax-d₆	Isotope-Labeled Compounds	Others
Squalene-d6 is a deuterium labeled Squalene. Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity .

HY-N4113

Glycycoumarin	Keap1-Nrf2 AMPK	Cancer
Glycycoumarin is a potent antispasmodic agent. Glycycoumarin is a major bioactive coumarin of licorice and exhibits antispasmodic activity. Glycycoumarin also has hepatoprotective effect. Glycycoumarin can be used for the research of abdominal pain and liver diseases .

HY-146058

NF-κB/PON1-IN-1	NF-κB Reactive Oxygen Species	Cancer
NF-κB/PON1-IN-1 (Compound 16) is a NF-κB/PON1 pathway inhibitor. NF-κB/PON1-IN-1 has antioxidant (IC₅₀ = 45.76 µM) and hepatoprotective activities .

HY-139637

(±)-Silybin Silibinin (mixture of Silybin A and Silybin B)	Others	Cancer
(±)-Silybin is the racemate of Silybin (HY-N0779A). Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity .

HY-N0779A

Silybin 2 Publications Verification Silibinin	Apoptosis	Inflammation/Immunology Cancer
Silybin is a flavonolignan isolated from milk thistle (Silybum marianum) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity .

HY-N4043

Hirsutanonol 5-O-β-D-glucopyranoside Hirsutanonol 5-O-glucoside	Others	Cancer
Hirsutanonol 5-O-glucoside is a diarylheptanoid derivatives that can be isolated from Alnus hirsuta. Hirsutanonol 5-O-glucoside exhibits significant hepatoprotective effects against t-BHP-induced toxicity in HepG2 cells with 42.8% protection .

HY-114360

Taurohyodeoxycholic acid	Endogenous Metabolite	Metabolic Disease
Taurohyodeoxycholic acid is the tauroconjugated form of Hyodeoxycholic acid (HDCA, a dihydroxylated natural bile acid). Taurohyodeoxycholic acid induces a biliary phospholipid secretion and suggests a hepatoprotective potential. Taurohyodeoxycholic acid also can promote gallstone dissolution .

HY-N4037

Homopterocarpin (-)-Homopterocarpin; 3,9-Dimethoxypterocarpan	Monoamine Oxidase	Inflammation/Immunology
Homopterocarpin is an isoflavonoid that can be isolated from Pterocarpus erinaceus. Homopterocarpin has hepatoprotective and antioxidant properties. Homopterocarpin is a competitive reversible inhibitor of human monoamine oxidase-B with an IC₅₀ and a K_i of 0.72 and 0.21 μM for hMAO-B, respectively. Homopterocarpin can be used for the research of liver injury and oxidative stress .

HY-N0691

Schisandrin 2 Publications Verification Schizandrin; Schizandrol; Schizandrol-A	Autophagy	Inflammation/Immunology Cancer
Schisandrin (Schizandrin), a dibenzocyclooctadiene lignan, is isolated from the fruit of Schisandra chinensis Baill. Schisandrin exhibits antioxidant, hepatoprotective, anti-cancer and anti-inflammatory activities. Schisandrin also can reverses memory impairment in rats .

HY-N1506

Ganodermanontriol	Others	Cancer
Ganodermanontriol, a sterol isolated from Ganoderma lucidum, induces anti-inflammatory activity in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the expression of HO-1. Ganodermanontriol exhibits hepatoprotective activity .

HY-N1324

Sanggenon N	Others	Others
Sanggenon N is an isoprenylated flavonoid that can be isolated from the root bark of Morus alba.Sanggenon N has hepatoprotective activities on t-BHP-induced cell cytotoxicity in HepG2 cells with an EC₅₀ of 23.45 μM .

HY-N0057

3,4-Dicaffeoylquinic acid 2 Publications Verification 3,4-Di-O-caffeoylquinic acid; Isochlorogenic acid B	Glucosidase Influenza Virus Apoptosis Endogenous Metabolite	Infection Cancer
3,4-Dicaffeoylquinic acid (3,4-Di-O-caffeoylquinic acid), naturally isolated from Laggera alata, has antioxidative, DNA protective, neuroprotective and hepatoprotective properties. 3,4-Dicaffeoylquinic acid exerts apoptosis-mediated cytotoxicity and α-glucosidase inhibitory effects. 3,4-Dicaffeoylquinic acid possesses a unique mechanism of anti-influenza viral activity, that is, enhancing viral clearance by increasing TRAIL .

HY-163478

TNIK-IN-9	NF-κB	Inflammation/Immunology
TNIK-IN-9 (Compound 54) is a selective and potent NIK inhibitor, with an IC₅₀ of 1.27 nM. TNIK-IN-9 can inhibit pro-inflammatory cytokines and nitric oxide production. TNIK-IN-9 exhibits significant anti-inflammatory effects, improved mortality, and hepatoprotective effects in sepsis models .

HY-N0055

Chlorogenic acid Maximum Cited Publications 14 Publications Verification 3-O-Caffeoylquinic acid; Heriguard; NSC-407296	HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species Bacterial Influenza Virus Endogenous Metabolite	Infection Inflammation/Immunology Cancer
Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb. It is an orally active antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension compound .

HY-B0144A

Pitavastatin 5 Publications Verification NK-104	HMG-CoA Reductase (HMGCR) Autophagy Mitophagy Apoptosis	Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
Pitavastatin (NK-104) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC₅₀ of 5.8 nM in HepG2 cells. Pitavastatin is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects .

HY-B0144B

Pitavastatin sodium NK-104 sodium	HMG-CoA Reductase (HMGCR) Autophagy Mitophagy Apoptosis	Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
Pitavastatin (NK-104) sodium is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin sodium inhibits cholesterol synthesis from acetic acid with an IC₅₀ of 5.8 nM in HepG2 cells. Pitavastatin sodium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin sodium also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects .

HY-N7056

4'-Hydroxychalcone	Oxidative Phosphorylation Proteasome	Inflammation/Immunology Cancer
4'-Hydroxychalcone is a chalcone isolated from licorice root, with hepatoprotective activity. 4'-Hydroxychalcone inhibits TNFα-induced NF-κB activation via proteasome inhibition. 4'-Hydroxychalcone induces a rapid potassium release from mitochondrial vesicles and causes deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria .

HY-N0148A

Rutin hydrate 5+ Cited Publications Rutoside hydrate; Quercetin 3-O-rutinoside hydrate	Amyloid-β Autophagy Apoptosis Endogenous Metabolite	Neurological Disease Cancer
Rutin (Rutoside) hydrate is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin hydrate can cross the blood brain barrier. Rutin hydrate attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress .

HY-N0711

Carvacrol 2 Publications Verification Cymophenol	Notch Apoptosis Fungal Endogenous Metabolite Bacterial	Infection Inflammation/Immunology Cancer
Carvacrol is an orally active monoterpenic phenol that can be extract from an abundant number of aromatic plants, including thyme and oregano, possessing antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, hepatoprotective, spasmolytic, and vasorelaxant properties. Carvacrol also causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1, and induces apoptosis. Carvacrol is used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations .

HY-N0416

Cucurbitacin B 5+ Cited Publications	Integrin Autophagy Apoptosis Endogenous Metabolite ROS Kinase COX	Others Neurological Disease Inflammation/Immunology Cancer
Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids and is oral active. Cucurbitacin B inhibits tumor cell growth, migration and invasion and cycle arrest, but induces cell apoptosis. Cucurbitacin B has potent anti-inflammatory, antioxidant, antiviral, hypoglycemic, hepatoprotective, neuroprotective activity .

HY-N0148

Rutin 5+ Cited Publications Rutoside; Quercetin 3-O-rutinoside	Amyloid-β Autophagy Apoptosis Endogenous Metabolite	Inflammation/Immunology Cancer
Rutin (Rutoside) is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin is also a CBR1 inhibitor, which can cross the blood brain barrier. Rutin attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress .

HY-126052

Gnetol	COX Tyrosinase HDAC	Metabolic Disease Cancer
Gnetol is a phenolic compound isolated from the root of Gnetum montanum . Gnetol potently inhibits COX-1 (IC₅₀ of 0.78 μM) and HDAC. Gnetol is a potent tyrosinase inhibitor with an IC₅₀ of 4.5 μM for murine tyrosinase and suppresses melanin biosynthesis. Gnetol has antioxidant, antiproliferative, anticancer and hepatoprotective activity. Gnetol also possesses concentration-dependent α-Amylase, α-glucosidase, and adipogenesis activities .

HY-N0664

Aucubin 5+ Cited Publications	Bacterial	Infection Neurological Disease Inflammation/Immunology Cancer
Aucubin, an iridoid glucoside, is isolated from Plantago asiatica, Eucommia ulmoides, the leaves of Aucuba japonica and more recently from butterfly larva. Aucubin has many biological activities, such as antioxidant, anti-aging, anti-inflammatory, antimicrobial, anti-fibrotic, anti-cancer, hepatoprotective, neuroprotective and osteoprotective effects .

HY-N0368

Linalool 1 Publications Verification	Apoptosis iGluR Endogenous Metabolite Bacterial	Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities .

HY-W032013S3

1-Octanol-d5 Octanol-d₅	Calcium Channel Endogenous Metabolite Isotope-Labeled Compounds	Others
1-Octanol-d₅ is deuterated labeled Carvacrol (HY-N0711). Carvacrol is an orally active monoterpenic phenol that can be extract from an abundant number of aromatic plants, including thyme and oregano, possessing antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, hepatoprotective, spasmolytic, and vasorelaxant properties. Carvacrol also causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1, and induces apoptosis. Carvacrol is used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations .

HY-N1989

Bacoside A

Bacoside A exhibits hepatoprotective activity .
HY-N2155

Tubuloside A

Tubuloside A is a phenylethanoid glycoside with antioxidative effect and hepatoprotective activity.

HY-W010201S

Citronellol-d6 (±)-Citronellol-d₆; (±)-β-Citronellol-d₆	Reactive Oxygen Species Isotope-Labeled Compounds	Cancer
Citronellol-d₆ is deuterated labeled Linalool (HY-N0368). Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N5092

7-Methylcoumarin	Microorganisms Source classification Coumarins Metabolic Disease Phenylpropanoids Disease Research Fields	Others
7-Methylcoumarin, a coumarin, exhibits strong hepatoprotective activity and potent antioxidant effect .

HY-N2412

Irisolidone	Flavonoids Neurological Disease Classification of Application Fields Leguminosae Source classification Phenols Polyphenols Plants Pueraria lobata (Willd.) Ohwi var. montana (Lour.)van der Maesen Disease Research Fields Isoflavones Cancer	Chloride Channel
Irisolidone is a major isoflavone found in Pueraria lobata flowers. Irisolidone exhibits potent hepatoprotective activity. Irisolidone shows the high efficacy for volume-regulated anion channels (VRAC) blockade (IC₅₀=9.8 μM) .

HY-N11660

*weak Hepatoprotective* agent-1**	Structural Classification Source classification Lignans Phenylpropanoids Plants Compositae Gueldenstaedtia verna (Georgi) Boriss.	Others
weak Hepatoprotective agent-1 (Compound 11) is a natural product that can be isolated from the fruits of Arctium lappa L.. weak Hepatoprotective agent-1 exhibits weak hepatoprotective activities at a concentration of 10 μM .

HY-N11448

Bupleuroside XIII	Triterpenes Structural Classification Terpenoids Source classification Plants Umbelliferae Carphephorus corymbosus (Nutt.) Torr. & A.Gray	Others
Bupleuroside XIII is a natural hepatoprotective saponin .

HY-N11563

Potentillanoside A	Triterpenes Structural Classification Terpenoids Source classification Rosaceae Potentilla anserina Linn. Plants	Others
Potentillanoside A is a natural compound with hepatoprotective effect .

HY-N0975

1,11b-Dihydro-11b-hydroxymaackiain	Erycibe ferruginea C. Y. Wu Source classification Plants Other Flavonoids Convolvulaceae	Others
1,11b-Dihydro-11b-hydroxymaackiain, a pterocarpane extract from the stems of Erycibe expansa, show a hepatoprotective effect .

HY-N4107

Phyllanthin	Phyllanthus urinaria Linn. Classification of Application Fields Source classification Lignans Metabolic Disease Euphorbiaceae Phenylpropanoids Plants Disease Research Fields	Others
Phyllanthin is a major bioactive lignan component of Phyllanthus amarus. Phyllanthin exhibits high antioxidative and hepatoprotective properties .

HY-115363

Curcumenone	Terpenoids Sesquiterpenes Source classification Plants Curcuma phaeocaulis Valeton Zingiberaceae	Others
Curcumenone is a major constituent of the plants of medicinally important genus of Curcuma. Curcumenone, a caraborane type sesquiterpene has been reported to be a vasorelaxant, hepatoprotective and an effective inhibitor of intoxication .

HY-106947

SY-640	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
SY-640 is an Acetamide derivative and has potent hepatoprotective effect. SY-640 reduces Propionibacterium acnes and Lipopolysaccharide-induced liver injury in mice .

HY-N10436

Anti-inflammatory agent 30	Source classification Phenols Dicerothamnus rhinocerotis Plants Umbelliferae	Others
Anti-inflammatory agent 30 (Compound 5) is an anti-inflammatory agent with hepatoprotective activity .

HY-N10434

Anti-inflammatory agent 28	Source classification Phenols Dicerothamnus rhinocerotis Plants Umbelliferae	Others
Anti-inflammatory agent 28 (Compound 9) is an anti-inflammatory agent with hepatoprotective activity .

HY-N10435

Anti-inflammatory agent 29	Source classification Phenols Dicerothamnus rhinocerotis Plants Umbelliferae	Others
Anti-inflammatory agent 29 (Compound 7) is an anti-inflammatory agent with hepatoprotective activity .

HY-N10380

Inonotusol F	Natural Products Microorganisms Source classification	Others
Inonotusol F is a triterpene isolated from Inonotus obliquus. Inonotusol F shows hepatoprotective effects against D-galactosamine-induced WB-F344 cell damage .

HY-N7543

Schisantherin D	Infection Schisandra sphenanthera Rehd. et Wils Classification of Application Fields Source classification Lignans Phenylpropanoids Plants Schisandraceae Disease Research Fields	HIV
Schisantherin D is a dibenzocyclooctadiene lignan isolated from the fruit of Schisandra sphenanthera. Schisantherin D shows anti-HIV replication activities with an EC₅₀ of 0.5 μg/mL. Schisantherin D inhibits endothelin receptor B (ETBR) and has hepatoprotective effects .

HY-N5083

Saponarin 1 Publications Verification	Flavonoids Classification of Application Fields Flavones Dipsacaceae Dipsacus sativus (Linn.) Honck. Source classification Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology	Others
Saponarin is a natural flavonoid isolated from Gypsophila trichotoma, with antioxidant, anti-inflammatory and hepatoprotective activities. Saponarin activates AMPK in a calcium-dependent manner, thus regulating gluconeogenesis and glucose uptake .

HY-125129

Carlinoside	Structural Classification Flavonoids Classification of Application Fields Flavones Cymbopogon citratus Gramineae Source classification Other Diseases Phenols Polyphenols Plants Disease Research Fields	Keap1-Nrf2
Carlinoside is a flavone glycoside with hepatoprotective efficiency. Carlinoside reduces hepatic bilirubin accumulation by stimulating bilirubin-UGT activity through Nrf2 gene expression. Carlinoside has the potential to intervene hyperbilirubinemia due to liver dysfunction .

HY-N1521

Rehmannic acid Lantadene A	Triterpenes Classification of Application Fields Terpenoids Verbenaceae Source classification Plants Disease Research Fields Inflammation/Immunology Lantana camaraLinn.	Others
Rehmannic acid (lantadene A) is a compound isolated from Lantana camara. Rehmannic acid shows considerable in vitro antioxidant, free radical scavenging capacity activities in a dose dependant manner. Rehmannic acid is a promising candidate for use as an antioxidant and hepatoprotective agent .

HY-N12072

3'-Methoxy-3,5,4'-trihydroxyflavone-7-neohesperidoside	Structural Classification Flavonols Flavonoids Cleome droserifolia (Forssk.) Delile Source classification Plants Capparidaceae	Others
3'-Methoxy-3,5,4'-trihydroxyflavone-7-neohesperidoside is a flavonoid that can be isolated from Cleome droserifolia. 3'-Methoxy-3,5,4'-trihydroxyflavone-7-neohesperidoside has moderate hepatoprotective activity ..

HY-N4113

Glycycoumarin	Classification of Application Fields Leguminosae Source classification Coumarins Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer	Keap1-Nrf2 AMPK
Glycycoumarin is a potent antispasmodic agent. Glycycoumarin is a major bioactive coumarin of licorice and exhibits antispasmodic activity. Glycycoumarin also has hepatoprotective effect. Glycycoumarin can be used for the research of abdominal pain and liver diseases .

HY-139637

(±)-Silybin Silibinin (mixture of Silybin A and Silybin B)	Structural Classification Flavanonols Flavonoids Source classification Cyamopsis tetragonoloba (L.) Taub. Plants Compositae	Others
(±)-Silybin is the racemate of Silybin (HY-N0779A). Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity .

HY-N0779A

Silybin 2 Publications Verification Silibinin	Structural Classification Classification of Application Fields Source classification Cyamopsis tetragonoloba (L.) Taub. Plants Compositae Flavanonols Flavonoids Glycine soya Phenols Polyphenols Inflammation/Immunology Disease Research Fields	Apoptosis
Silybin is a flavonolignan isolated from milk thistle (Silybum marianum) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity .

HY-N4043

Hirsutanonol 5-O-β-D-glucopyranoside Hirsutanonol 5-O-glucoside	Structural Classification Source classification Phenols Polyphenols Alnus hirsuta Turczaninow ex Ruprecht Plants Betulaceae	Others
Hirsutanonol 5-O-glucoside is a diarylheptanoid derivatives that can be isolated from Alnus hirsuta. Hirsutanonol 5-O-glucoside exhibits significant hepatoprotective effects against t-BHP-induced toxicity in HepG2 cells with 42.8% protection .

HY-114360

Taurohyodeoxycholic acid	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Taurohyodeoxycholic acid is the tauroconjugated form of Hyodeoxycholic acid (HDCA, a dihydroxylated natural bile acid). Taurohyodeoxycholic acid induces a biliary phospholipid secretion and suggests a hepatoprotective potential. Taurohyodeoxycholic acid also can promote gallstone dissolution .

HY-N4037

Homopterocarpin (-)-Homopterocarpin; 3,9-Dimethoxypterocarpan	Other Terpenoids Pterocarpus indicus willd. Structural Classification Leguminosae Terpenoids Source classification Plants	Monoamine Oxidase
Homopterocarpin is an isoflavonoid that can be isolated from Pterocarpus erinaceus. Homopterocarpin has hepatoprotective and antioxidant properties. Homopterocarpin is a competitive reversible inhibitor of human monoamine oxidase-B with an IC₅₀ and a K_i of 0.72 and 0.21 μM for hMAO-B, respectively. Homopterocarpin can be used for the research of liver injury and oxidative stress .

HY-N0691

Schisandrin 2 Publications Verification Schizandrin; Schizandrol; Schizandrol-A	Classification of Application Fields Source classification Lignans Phenylpropanoids Plants Schisandraceae Disease Research Fields Schisandra chinensis (Turcz.) Baill. Cancer	Autophagy
Schisandrin (Schizandrin), a dibenzocyclooctadiene lignan, is isolated from the fruit of Schisandra chinensis Baill. Schisandrin exhibits antioxidant, hepatoprotective, anti-cancer and anti-inflammatory activities. Schisandrin also can reverses memory impairment in rats .

HY-N1506

Ganodermanontriol	Other Terpenoids Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Terpenoids Source classification Polyporaceae Plants Endogenous metabolite Disease Research Fields Cancer	Others
Ganodermanontriol, a sterol isolated from Ganoderma lucidum, induces anti-inflammatory activity in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the expression of HO-1. Ganodermanontriol exhibits hepatoprotective activity .

HY-N1324

Sanggenon N	Structural Classification Flavanonols Flavonoids Source classification Phenols Polyphenols Plants Moraceae Morus alba Linn.	Others
Sanggenon N is an isoprenylated flavonoid that can be isolated from the root bark of Morus alba.Sanggenon N has hepatoprotective activities on t-BHP-induced cell cytotoxicity in HepG2 cells with an EC₅₀ of 23.45 μM .

HY-N0057

3,4-Dicaffeoylquinic acid 2 Publications Verification 3,4-Di-O-caffeoylquinic acid; Isochlorogenic acid B	Infection Caprifoliaceae Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Polyphenols Plants Endogenous metabolite Disease Research Fields	Glucosidase Influenza Virus Apoptosis Endogenous Metabolite
3,4-Dicaffeoylquinic acid (3,4-Di-O-caffeoylquinic acid), naturally isolated from Laggera alata, has antioxidative, DNA protective, neuroprotective and hepatoprotective properties. 3,4-Dicaffeoylquinic acid exerts apoptosis-mediated cytotoxicity and α-glucosidase inhibitory effects. 3,4-Dicaffeoylquinic acid possesses a unique mechanism of anti-influenza viral activity, that is, enhancing viral clearance by increasing TRAIL .

HY-N0055

Chlorogenic acid Maximum Cited Publications 14 Publications Verification 3-O-Caffeoylquinic acid; Heriguard; NSC-407296	Structural Classification Caprifoliaceae Classification of Application Fields Anti-aging Lonicera japonica Thunb. Source classification Plants Endogenous metabolite Infection Human Gut Microbiota Metabolites Microorganisms Simple Phenylpropanols Phenols Polyphenols Phenylpropanoids Inflammation/Immunology Disease Research Fields Cancer	HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species Bacterial Influenza Virus Endogenous Metabolite
Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb. It is an orally active antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension compound .

HY-N7056

4'-Hydroxychalcone	Structural Classification Classification of Application Fields Source classification Plants Endogenous metabolite Chalcones Monophenols Flavonoids Leguminosae Phenols Inflammation/Immunology Disease Research Fields Glycyrrhiza uralensis Fisch.	Oxidative Phosphorylation Proteasome
4'-Hydroxychalcone is a chalcone isolated from licorice root, with hepatoprotective activity. 4'-Hydroxychalcone inhibits TNFα-induced NF-κB activation via proteasome inhibition. 4'-Hydroxychalcone induces a rapid potassium release from mitochondrial vesicles and causes deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria .

HY-N0148A

Rutin hydrate 5+ Cited Publications Rutoside hydrate; Quercetin 3-O-rutinoside hydrate	Flavonols Structural Classification Flavonoids other families Source classification Phenols Polyphenols Plants	Amyloid-β Autophagy Apoptosis Endogenous Metabolite
Rutin (Rutoside) hydrate is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin hydrate can cross the blood brain barrier. Rutin hydrate attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress .

HY-N0711

Carvacrol 2 Publications Verification Cymophenol	Structural Classification Monophenols Preservatives Classification of Application Fields Labiatae Phenols Plants Inflammation/Immunology Disease Research Fields Food Research	Notch Apoptosis Fungal Endogenous Metabolite Bacterial
Carvacrol is an orally active monoterpenic phenol that can be extract from an abundant number of aromatic plants, including thyme and oregano, possessing antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, hepatoprotective, spasmolytic, and vasorelaxant properties. Carvacrol also causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1, and induces apoptosis. Carvacrol is used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations .

HY-N0416

Cucurbitacin B 5+ Cited Publications	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Cucurbitaceae Trichosanthes cucumerina L. Plants Endogenous metabolite Disease Research Fields Cancer	Integrin Autophagy Apoptosis Endogenous Metabolite ROS Kinase COX
Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids and is oral active. Cucurbitacin B inhibits tumor cell growth, migration and invasion and cycle arrest, but induces cell apoptosis. Cucurbitacin B has potent anti-inflammatory, antioxidant, antiviral, hypoglycemic, hepatoprotective, neuroprotective activity .

HY-N0148

Rutin 5+ Cited Publications Rutoside; Quercetin 3-O-rutinoside	Flavonols Structural Classification Classification of Application Fields Source classification Plants Flavonoids other families Sunscreen Leguminosae Phenols Polyphenols Cosmetic Research Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer	Amyloid-β Autophagy Apoptosis Endogenous Metabolite
Rutin (Rutoside) is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin is also a CBR1 inhibitor, which can cross the blood brain barrier. Rutin attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress .

HY-126052

Gnetol	Structural Classification Stilbenes Classification of Application Fields Source classification Phenols Polyphenols Metabolic Disease Gnetaceae Plants Disease Research Fields Gnetum montanum Markgr.	COX Tyrosinase HDAC
Gnetol is a phenolic compound isolated from the root of Gnetum montanum . Gnetol potently inhibits COX-1 (IC₅₀ of 0.78 μM) and HDAC. Gnetol is a potent tyrosinase inhibitor with an IC₅₀ of 4.5 μM for murine tyrosinase and suppresses melanin biosynthesis. Gnetol has antioxidant, antiproliferative, anticancer and hepatoprotective activity. Gnetol also possesses concentration-dependent α-Amylase, α-glucosidase, and adipogenesis activities .

HY-N0664

Aucubin 5+ Cited Publications	Infection Structural Classification Eucommia ulmoides Oliver Iridoids Neurological Disease Classification of Application Fields Terpenoids Source classification Eucommiaceae Plants Inflammation/Immunology Disease Research Fields	Bacterial
Aucubin, an iridoid glucoside, is isolated from Plantago asiatica, Eucommia ulmoides, the leaves of Aucuba japonica and more recently from butterfly larva. Aucubin has many biological activities, such as antioxidant, anti-aging, anti-inflammatory, antimicrobial, anti-fibrotic, anti-cancer, hepatoprotective, neuroprotective and osteoprotective effects .

HY-N0368

Linalool 1 Publications Verification	Cardiovascular Disease Structural Classification Other Monoterpenes Scutellaria indica L. Microorganisms Classification of Application Fields Terpenoids Source classification Umbelliferae Plants Endogenous metabolite Disease Research Fields	Apoptosis iGluR Endogenous Metabolite Bacterial
Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities .

HY-N12442

Sarmenoside III	Structural Classification Source classification Phenols Polyphenols Plants Capparidaceae Cleome chelidonii L.f.	Others
Sarmenoside III is a flavonol glycoside with hepatoprotective activity isolated from Sedum sarmentosum.

HY-N7919

Celosin H	Structural Classification Celosia argentea Linn. Polysaccharides Source classification Amaranthaceae Plants Saccharides	Others
Celosin H is a hepatoprotective triterpenoid saponin that can be isolated from Celosiae Semen .

HY-115394

Soyasaponin IV	Triterpenes Structural Classification Glycine soya Classification of Application Fields Leguminosae Terpenoids Source classification Other Diseases Pueraria montana var. thomsonii (Bentham) M. R. Almeida Plants Disease Research Fields	Others
Soyasaponin IV, isolated from the aerial parts of Glycine soya, exhibits a hepatoprotective action .

HY-N0806

Sweroside	Filago spathulata Presl. Structural Classification Monophenols Classification of Application Fields Labiatae Phenols Metabolic Disease Plants Disease Research Fields	Others
Sweroside, isolated from Lonicera japonica, exhibits cytoprotective, anti-osteoporotic, and hepatoprotective effect .

HY-N9880

Tamarixin	Structural Classification Monophenols Flavonoids Flavones Leguminosae Source classification Phenols Plants Saccharides Astragalus membranaceus (Fisch.) Bunge Monosaccharides	Bacterial
Tamarixin is flavonoid that isolated from Astragalus tanae Sosn that has hepatoprotective, antioxidant, anticancer, and antimicrobial activities .

HY-N7680

Neopuerarin A	Flavonoids Classification of Application Fields Leguminosae Source classification Phenols Polyphenols Metabolic Disease Pueraria montana (Loureiro) Merrill Plants Disease Research Fields Isoflavones	Others
Neopuerarin A is an isoflavones isolated from the water extraction of the dried roots of Pueraria lobata (Willd.). Neopuerarin A shows significant hepatoprotective effect .

HY-N10359

Isoandrographolide	Andrographis paniculata (Burm. F.) Nees Classification of Application Fields Acanthaceae Terpenoids Source classification Diterpenoids Plants Disease Research Fields Inflammation/Immunology	NOD-like Receptor (NLR)
Isoandrographolide possesses cell differentiation inducing and hepatoprotective effect. Isoandrographolide inhibits NLRP3 inflammasome activation and attenuates silicosis in mice .

HY-N7680A

Neopuerarin B	Flavonoids Classification of Application Fields Leguminosae Source classification Phenols Polyphenols Metabolic Disease Pueraria montana (Loureiro) Merrill Plants Disease Research Fields Isoflavones	Others
Neopuerarin B is an isoflavones isolated from the water extraction of the dried roots of Pueraria lobata (Willd.). Neopuerarin B shows significant hepatoprotective effect .

HY-N1616

1β-Hydroxyeuscaphic acid	Triterpenes other families Classification of Application Fields Terpenoids Source classification Other Diseases Plants Disease Research Fields	Apoptosis
1β-Hydroxyeuscaphic acid has significant hepatoprotective activity by lowering the leakage of intracellular enzymes, reducing the oxidation of proteins and decreasing the incidence of apoptosis .

HY-150521

Hispolon	Infection Structural Classification Microorganisms Classification of Application Fields Phenols Polyphenols Metabolic Disease Disease Research Fields Cancer	Antibiotic
Hispolon, a polyphenol, can be isolated from Phellinus linteus. Hispolon possesses anticancer, antidiabetic, antioxidant, antiviral, hepatoprotective, anti-diabetic, and anti-inflammatory activities .

HY-N0344

Farrerol 1 Publications Verification	Flavonoids Classification of Application Fields Neurological Disease Rhododendron dauricum Linn. Flavonones Source classification Phenols Polyphenols Plants Ericaceae Disease Research Fields Inflammation/Immunology	Others
Farrerol is a bioactive constituent of Rhododendron, with broad activities such as anti-oxidative, anti-inflammatory, anti-tumor, neuroprotective and hepatoprotective effects .

HY-N12432

Glomeratide A	Structural Classification Polygala chinensis Linnaeus Source classification Polygalaceae Phenols Polyphenols Plants	Others
Glomeratide A is a benzophenone C-glucoside with hepatoprotective effects. Glomeratide A has a protective effect against d-galactosamine-induced hepatotoxicity in rat liver epithelial stem-like cells.

HY-N12426

Heilaohuguosu F	Structural Classification Source classification Lignans Phenylpropanoids Plants Kadsura coccinea (Lem.) A. C. Smith Schisandraceae	Others
Heilaohuguosu F (compound 6) is a tetrahydrofuranolignan with weak hepatoprotective effects. Heilaohuguosu F has a mild protective effect against APAP-induced hepatotoxicity in HepG2 cells.

Cat. No.	Product Name	Chemical Structure

HY-N1214S

Squalene-d6
Squalene-d6 is a deuterium labeled Squalene. Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity .

HY-N0108S

Physcion-d3
Physcion-d₃ (Parietin-d₃) is the deuterium labeled Physcion (HY-N0108). Physcion acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC₅₀ and a K_d of 38.5 μM and 26.0 μM, respectively. Physcion exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects .

HY-W032013S3

1-Octanol-d5

1-Octanol-d₅ is deuterated labeled Carvacrol (HY-N0711). Carvacrol is an orally active monoterpenic phenol that can be extract from an abundant number of aromatic plants, including thyme and oregano, possessing antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, hepatoprotective, spasmolytic, and vasorelaxant properties. Carvacrol also causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1, and induces apoptosis. Carvacrol is used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations .

HY-W010201S

Citronellol-d6

Citronellol-d₆ is deuterated labeled Linalool (HY-N0368). Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities .

HY-W010410S

Oct-1-en-3-ol-d3

Oct-1-en-3-ol-d₃ is deuterated labeled Linalool (HY-N0368). Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities .

HY-N0055S

Chlorogenic acid-13C3

Chlorogenic acid- ¹³C₃ (Heriguard- ¹³C₃; NSC-407296- ¹³C₃) is ¹³C- and ¹⁵N-labeled Chlorogenic acid (HY-N0055). Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb.. It plays several important and therapeutic roles such as antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension .

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