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Calcitonin (human) is a hypocalcemic hormone. Calcitonin can lower blood calcium levels and inhibit bone resorption. Calcitonin can be used in hypercalcemia or osteoporosis research .
β-CGRP, human TFA (Human β-CGRP TFA) is one of calcitonin peptides, acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells .
β-CGRP, human (Human β-CGRP) is one of calcitonin peptides, acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells .
β-CGRP, human acetate (Human β-CGRP acetate) is one of calcitonin peptides, acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells .
CGRP antagonist 4 is an antagonist of calcitonin gene-related peptide (CGRP) receptor. CGRP antagonist 4 shows the highest affinity for CGRP receptors in the human brain. CGRP antagonist 4 can be used to study the binding properties of non-peptide calcitonin gene-related peptide (CGRP) receptor antagonist (gepants) in rat, pig and human menes .
Erenumab is a fully human monoclonal antibody. Erenumab inhibits the calcitonin gene–related peptide (CGRP) receptor. Erenumab can be used for the prevention of episodic migraine .
Eptinezumab is a human monoclonal antibody. Eptinezumab binds to calcitonin gene-related peptide (CGRP) and blocks its binding to the receptor. Eptinezumab can be used for the prevention of migraine in adults .
α-CGRP(human) is a regulatory neuropeptide of 37 amino acids. α-CGRP(human) is widely distributed in the central and peripheral nervous system. α-CGRP(human) is a potent vasodilator .
Telcagepant (MK-0974) is an orally active calcitonin gene-related peptide (CGRP) receptor antagonist with Kis of 0.77 nM and 1.2 nM for human and rhesus CGRP receptors, respectively.
Olcegepant (BIBN-4096) is a potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and Ki of 14.4 pM for human CGRP .
Olcegepant hydrochloride (BIBN-4096 hydrochloride) is a potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and with a Ki of 14.4 pM for human CGRP .
Adrenomedullin (AM) (22-52), human, an NH2 terminal truncated adrenomedullin analogue, is an adrenomedullin receptor antagonist, and also antagonizes the calcitonin generelated peptide (CGRP) receptor in the hindlimb vascular bed of the cat .
PHM-27 (human) is a human prepro-vasoactive intestinal polypeptide (27 amino acid). PHM-27 (human) is a potent the humancalcitonin receptor agonist with an EC50 of 11 nM. PHM-27 (human) efficiently enhances glucose-induced insulin secretion from beta cells by an autocrine mechanism .
Adrenomedullin (AM) (22-52), human (22-52-Adrenomedullin human) TFA, an NH2 terminal truncated adrenomedullin analogue, is an adrenomedullin receptor antagonist. Adrenomedullin (AM) (22-52), human also antagonizes the calcitonin generelated peptide (CGRP) receptor in the hindlimb vascular bed of the cat .
α-CGRP(human) TFA is a regulatory neuropeptide of 37 amino acids. α-CGRP(human) is widely distributed in the central and peripheral nervous system. α-CGRP(human) TFA is a potent vasodilator .
Calcitonin (human) is a hypocalcemic hormone. Calcitonin can lower blood calcium levels and inhibit bone resorption. Calcitonin can be used in hypercalcemia or osteoporosis research .
β-CGRP, human TFA (Human β-CGRP TFA) is one of calcitonin peptides, acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells .
β-CGRP, human (Human β-CGRP) is one of calcitonin peptides, acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells .
β-CGRP, human acetate (Human β-CGRP acetate) is one of calcitonin peptides, acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells .
α-CGRP(human) is a regulatory neuropeptide of 37 amino acids. α-CGRP(human) is widely distributed in the central and peripheral nervous system. α-CGRP(human) is a potent vasodilator .
Adrenomedullin (AM) (22-52), human, an NH2 terminal truncated adrenomedullin analogue, is an adrenomedullin receptor antagonist, and also antagonizes the calcitonin generelated peptide (CGRP) receptor in the hindlimb vascular bed of the cat .
PHM-27 (human) is a human prepro-vasoactive intestinal polypeptide (27 amino acid). PHM-27 (human) is a potent the humancalcitonin receptor agonist with an EC50 of 11 nM. PHM-27 (human) efficiently enhances glucose-induced insulin secretion from beta cells by an autocrine mechanism .
Adrenomedullin (AM) (22-52), human (22-52-Adrenomedullin human) TFA, an NH2 terminal truncated adrenomedullin analogue, is an adrenomedullin receptor antagonist. Adrenomedullin (AM) (22-52), human also antagonizes the calcitonin generelated peptide (CGRP) receptor in the hindlimb vascular bed of the cat .
α-CGRP(human) TFA is a regulatory neuropeptide of 37 amino acids. α-CGRP(human) is widely distributed in the central and peripheral nervous system. α-CGRP(human) TFA is a potent vasodilator .
Erenumab is a fully human monoclonal antibody. Erenumab inhibits the calcitonin gene–related peptide (CGRP) receptor. Erenumab can be used for the prevention of episodic migraine .
Eptinezumab is a human monoclonal antibody. Eptinezumab binds to calcitonin gene-related peptide (CGRP) and blocks its binding to the receptor. Eptinezumab can be used for the prevention of migraine in adults .
Calcitonin Protein, Human (HEK293, His), a recombinant human Calcitonin produced in HEK293 cells, has a His tag at the N-terminus. Calcitonin has an effect on decreasing osteoclast activity and has the potential for hypercalcemia research.
Calcitonin Protein, Human (His), is a recombinant human Calcitonin expressed in E. coli with a His tag at the N-terminus. Calcitonin has an effect on decreasing osteoclast activity and has the potential for hypercalcemia research.
Calcitonin, encoded by the CALCA gene, induces a swift yet transient reduction in blood calcium and phosphate levels by facilitating the incorporation of these ions into the bones. This physiological response highlights Calcitonin's role in regulating mineral homeostasis and underscores its impact on skeletal dynamics. Additionally, Katacalcin, a peptide derived from the same gene, emerges as a potent factor in lowering plasma calcium levels, further emphasizing the multifaceted influence of Calcitonin in orchestrating calcium metabolism. Calcitonin/CALCA Protein, Human (HEK293, N-His) is the recombinant human-derived Calcitonin/CALCA protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Calcitonin/CALCA Protein, Human (HEK293, N-His) is 116 a.a., with molecular weight of ~16.28 kDa.
Calcitonin R protein, a receptor for calcitonin, utilizes G proteins to activate adenylyl cyclase. Despite being sensitive to cholera toxin, it exhibits limited coupling to G proteins, leading to the inability to effectively activate adenylyl cyclase. Notably, following ligand binding, Calcitonin R does not undergo the conventional process of receptor internalization. Calcitonin R Protein, Human (HEK293, Fc) is the recombinant human-derived Calcitonin R protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Calcitonin R Protein, Human (HEK293, Fc) is 129 a.a., with molecular weight of ~42.1 kDa.
Calcitonin, encoded by the CALCA gene, causes a rapid and transient decrease in blood calcium and phosphate levels by promoting the incorporation of these ions into bone. This physiological response highlights the role of calcitonin in regulating mineral homeostasis and underlines its impact on skeletal dynamics. Calcitonin/CALCA Protein, Human (HEK293, Fc) is the recombinant human-derived Calcitonin/CALCA protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Calcitonin/CALCA Protein, Human (HEK293, Fc) is 116 a.a., with molecular weight of 40-48 kDa.
Calcitonin/CALCA protein acts as a vasodilator, dilating different blood vessels, including coronary, cerebral, and systemic vessels. Its presence in the central nervous system suggests its potential role as a neurotransmitter or neuromodulator. Calcitonin/CALCA Protein, Human (GST) is the recombinant human-derived Calcitonin/CALCA protein, expressed by E. coli , with N-GST labeled tag. The total length of Calcitonin/CALCA Protein, Human (GST) is 36 a.a., with molecular weight of ~30.6 kDa.
Calcitonin/CALCA protein acts as a vasodilator, dilating different blood vessels, including coronary, cerebral, and systemic vessels. Its presence in the central nervous system suggests its potential role as a neurotransmitter or neuromodulator. Calcitonin/CALCA Protein, Human (P. pastoris, His-SUMO) is the recombinant human-derived Calcitonin/CALCA protein, expressed by P. pastoris , with N-SUMO, N-6*His labeled tag. The total length of Calcitonin/CALCA Protein, Human (P. pastoris, His-SUMO) is 37 a.a., with molecular weight of 22 kDa.
CALCB Protein, Human (93a.a, HEK293, Fc), a recombinant human Calcitonin Gene-related Peptide 2 produced in HEK293 cells, has an Fc fragment at the C-terminus. Calcitonin gene-related peptide (CGRP), a 37-amino acid neuropeptide, is a highly potent vasodilator.
CALCB, known for its vasodilatory effects, induces dilation in various vessels, encompassing the coronary, cerebral, and systemic vasculature. Its notable abundance in the central nervous system suggests a potential role as a neurotransmitter or neuromodulator, underscoring its significance in physiological processes related to vascular regulation and neural signaling. CALCB Protein, Human (118a.a, HEK293, Fc) is the recombinant human-derived CALCB protein, expressed by HEK293 , with C-mFc labeled tag. The total length of CALCB Protein, Human (118a.a, HEK293, Fc) is 118 a.a., with molecular weight of ~37 kDa.
CGRP-1/2 Antibody is an unconjugated, approximately 3.8/14 kDa, rabbit-derived, anti-CGRP-1/2 polyclonal antibody. CGRP-1/2 Antibody can be used for: ELISA, IHC-P, IHC-F, IF expriments in human, rat, and predicted: mouse, chicken, pig, cow background without labeling.
CGRPR; CRLR; calcitonin receptor like precursor; calcitonin gene related peptide type 1 receptor; calcitonin receptor like; CGRP type 1 receptor; calcitonin gene related peptide type 1 receptor; calcitonin receptor like; calcitonin Receptor Like Receptor; CGRP type 1 receptor; CALRL_human.
WB, ELISA
Human, Mouse
CRLR Antibody is an unconjugated, approximately 50 kDa, rabbit-derived, anti-CALCRL polyclonal antibody. CALCRL Antibody can be used for: WB, ELISA expriments in human, mouse, and predicted: rat background without labeling.
Calcitonin receptor Antibody is an unconjugated, approximately 53 kDa, rabbit-derived, anti-Calcitonin receptor polyclonal antibody. Calcitonin receptor Antibody can be used for: ELISA, IHC-P, IHC-F, ICC, IF expriments in rat, and predicted: mouse background without labeling.
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