1. Search Result
Search Result
Results for "

lactate

" in MedChemExpress (MCE) Product Catalog:

101

Inhibitors & Agonists

1

Fluorescent Dye

3

Biochemical Assay Reagents

3

Peptides

10

Natural
Products

10

Recombinant Proteins

11

Isotope-Labeled Compounds

5

Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B2227
    Lactate
    3 Publications Verification

    Lactic acid

    Endogenous Metabolite Metabolic Disease Inflammation/Immunology Cancer
    Lactate (Lactic acid) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactate is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactate is an oncometabolite and has immune protective role of lactate in anti-tumor immunity .
    <em>Lactate</em>
  • HY-134757

    Others Others
    Lactate oxidase (EC 1.13.12.4) belongs to a group of FMN-dependent enzymes and they catalyze a conversion of lactate to pyruvate with a release of hydrogen peroxide. Lactate oxidase can be used in the detection of Lactate .
    <em>Lactate</em> oxidase, Microorganism
  • HY-B2227B
    Lactate sodium
    3 Publications Verification

    Lactic acid sodium

    Bacterial Metabolic Disease
    Lactate (Lactic acid) sodium is the product of glycogenolysis and glycolysis . Lactate (Lactic acid) sodium is an organic salt that is mainly used as a buffer and pH adjuster for injection solutions. Lactate sodium can be metabolized by the body into sodium bicarbonate, which in turn acts to increase the pH of the blood. Lactate sodium is used to improve metabolic acidosis and hypovolemic states. In terms of pharmaceutical preparations, Lactate sodium is often used in combination with sodium chloride, glucose, etc. to form normal saline or compound liquid intravenous injection . Lactate sodium also has antimicrobial activity, which can be used as a food preservative .
    <em>Lactate</em> sodium
  • HY-B2227BS

    Lactic acid-d4 sodium

    Isotope-Labeled Compounds Others
    Lactate-d4 (sodium) is the deuterium labeled Lactate sodium. Lactate sodium is the product of glycogenolysis and glycolysis. Lactate sodium functions in a variety of biochemical processes[1][2].
    <em>Lactate</em>-d4 sodium
  • HY-B2227C

    Lactic acid potassium

    Bacterial Infection Others
    Lactate (Lactic acid) potassium is used as a sodium chloride substitute in the elaboration of dry meat products. Lactate potassium (56%) and sodium diacetate (4%) mixture inhibit the development of L. sake and L. monocytogenes bacteria at 4℃ to extend the shelf life of food .
    <em>Lactate</em> potassium
  • HY-B2227BS1

    Lactic acid-d3 sodium

    Isotope-Labeled Compounds Others
    Lactate-d3 (sodium) is the deuterium labeled Lactate sodium. Lactate sodium is the product of glycogenolysis and glycolysis. Lactate sodium functions in a variety of biochemical processes[1][2].
    <em>Lactate</em>-d3 sodium
  • HY-B2227A
    Lactate calcium
    3 Publications Verification

    Lactic acid calcium

    Bacterial Cancer
    Lactate (Lactic acid) calcium is used by the beverage industry as a source of calcium to fortify fruit juice. Lactate calcium facilitates the growth and phytic acid degradation of soybean sprouts .
    <em>Lactate</em> calcium
  • HY-155382

    Monocarboxylate Transporter Others Cancer
    Lactate transportor 1 (compound 1) is an active lactate transporter in living cells. Lactate transportor 1 displays the cytotoxic effect, with IC50 values of 3.36, 3.27,5.58 and 7.66 μM in Hela, CAL27, MCF7 and MCF10A, respectively. Lactate transportor 1 has an additive effect with Cisplatin (HY-17394) observed in HeLa cells .
    <em>Lactate</em> transportor 1
  • HY-P2807G

    LAD, LD, L-LDH, (S)-lactate, LDH

    Others Others
    Lactate Dehydrogenase (LDH), Chicken Heart (LAD, LD, L-LDH, (S)-Lactate, LDH) is a biological material or organic compound that can be used in life science research .
    <em>Lactate</em> Dehydrogenase (LDH), Chicken Heart
  • HY-B2227BS2

    Lactic acid-13C sodium

    Isotope-Labeled Compounds Metabolic Disease
    Lactate- 13C (sodium) is the 13C labeled Lactate sodium[1]. Lactate (Lactic acid) sodium is the product of glycogenolysis and glycolysis. Lactate (Lactic acid) sodium functions in a variety of biochemical processes[2].
    <em>Lactate</em>-13C sodium
  • HY-P2807F

    LAD, LD, L-LDH, (S)-lactate: NAD+ oxidoreductase

    Others Others
    Lactate Dehydrogenase (LDH), Bovine Heart (LAD, LD, L-LDH, (S)-Lactate: NAD+ oxidoreductase) is a biological material or organic compound that can be used in life science research .
    <em>Lactate</em> Dehydrogenase (LDH), Bovine Heart
  • HY-B2227BS3

    Lactic acid-13C-1 sodium

    Isotope-Labeled Compounds Metabolic Disease
    Lactate- 13C-1 (sodium) is the 13C labeled Lactate (sodium)[1]. Lactate (Lactic acid) sodium is the product of glycogenolysis and glycolysis. Lactate (Lactic acid) sodium functions in a variety of biochemical processes[2].
    <em>Lactate</em>-13C-1 sodium
  • HY-P2807A

    LDH, Lactic Dehydrogenase

    Others Others
    Lactate Dehydrogenase (LDH), Porcine Heart (LDH, Lactic Dehydrogenase) is a biological material or organic compound that can be used in life science research .
    <em>Lactate</em> Dehydrogenase (LDH), Porcine Heart
  • HY-P2807C

    LDH-2 (3H1M), LD2

    Others Others
    Lactate Dehydrogenase 2 (LDH-2), Human Erythrocytes (LDH-2 (3H1M), LD2) is a biological material or organic compound that can be used in life science research .
    <em>Lactate</em> Dehydrogenase 2 (LDH-2), Human Erythrocytes
  • HY-P2807H

    LD-5 Isoenzyme, LDH-5 Isoenzyme, 4M Isoenzyme

    Others Others
    Lactate Dehydrogenase 5 (LDH-5), Human Liver (LD-5 Isoenzyme, LDH-5 Isoenzyme, 4M Isoenzyme) is a biological material or organic compound that can be used in life science research .
    <em>Lactate</em> Dehydrogenase 5 (LDH-5), Human Liver
  • HY-P2807B

    LDH-1, LD1 isoenzyme, 4H isoenzyme, Lactic Dehydrogenase

    Others Others
    Lactate Dehydrogenase 1 (LDH-1), Human Erythrocytes (LDH-1, LD1 isoenzyme, 4H isoenzyme, Lactic Dehydrogenase) is a biological material or organic compound that can be used in life science research .
    <em>Lactate</em> Dehydrogenase 1 (LDH-1), Human Erythrocytes
  • HY-P2807D

    LDH-3, LD3, LD-3, 2H2M

    Others Others
    Lactate Dehydrogenase 3 (LDH-3), Human Erythrocytes (LDH-3, LD3, LD-3, 2H2M) is a biological material or organic compound that can be used in life science research .
    <em>Lactate</em> Dehydrogenase 3 (LDH-3), Human Erythrocytes
  • HY-P2807E

    LDH-4 isoenzyme, 1H3M isoenzyme, ld4 isoenyzme

    Others Others
    Lactate Dehydrogenase 4 (LDH-4), Human Liver (LDH-4 isoenzyme, 1H3M isoenzyme, ld4 isoenyzme) is a biological material or organic compound that can be used in life science research .
    <em>Lactate</em> Dehydrogenase 4 (LDH-4), Human Liver
  • HY-W016484

    Others Others
    Benzyl lactate is a kind lactate ester .
    Benzyl <em>lactate</em>
  • HY-10224A

    LBH589 lactate; NVP-LBH589 lactate

    HDAC HIV Autophagy Apoptosis Infection Cancer
    Panobinostat lactate is a potent and orally active non-selective HDAC inhibitor. Panobinostat lactate has antineoplastic activities. Panobinostat lactate effectively disrupts HIV latency. Panobinostat lactate induces cell apoptosis and autophagy. Panobinostat lactate can be used for the study of refractory or relapsed multiple myeloma .
    Panobinostat <em>lactate</em>
  • HY-B1530

    (±)-Ammonium lactate

    Bacterial Infection
    Ammonium lactate is the ammonium salt of lactic acid, with mild anti-bacterial properties. Ammonium lactate can be used for the research of xerosis .
    Ammonium <em>lactate</em>
  • HY-W040298

    Bay-09867 lactate

    Topoisomerase Apoptosis Antibiotic Bacterial Mitochondrial Metabolism Reactive Oxygen Species Infection Cancer
    Ciprofloxacin (Bay-09867) lactate is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin lactate induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin lactate has anti-proliferative activity and induces apoptosis. Ciprofloxacin lactate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity .
    Ciprofloxacin <em>lactate</em>
  • HY-113916

    AT13387 lactate

    HSP Cancer
    Onalespib lactate is a potent and cross the blood-brain barrier heat-shock-protein-90 (Hsp90) inhibitor with an Kd value of 0.71 nM. Onalespib lactate inhibits the proliferation, survival and migration. Onalespib lactate decreases the expression of EGFR, p-EGFR, AKT, P-AKT, ERK1/2, P-ERK1/2, S6, P-S6 protein. Onalespib lactate shows antitumor activity. Onalespib lactate has the potential for the research of non-small cell lung cancer (NSCLC) .
    Onalespib <em>lactate</em>
  • HY-14252A

    Win 47203 lactate

    Others Cardiovascular Disease
    Milrinone lactate is a potent inotropic dilating agent. Milrinone lactate shows simultaneous positive inotropic and vasodilating activities. Milrinone lactate promotes reduction of SVR and PVR in patients with DCM and NYHA class III and IV of heart failure. Milrinone lactate has the potential for the research of cardiovascular function after cardiac surgery and in septic shock .
    Milrinone <em>lactate</em>
  • HY-17395B

    TDT 067 lactate

    Antibiotic Fungal Bacterial Infection
    Terbinafine lactate (TDT 067 lactate) is an orally active and potent antifungal agent. Terbinafine lactate is a potent non-competitive inhibitor of squalene epoxidase from Candida, with a Ki of 30 nM. Terbinafine lactate also shows antibacterial activity against certain Gram-positive and Gram-negative bacteria . Terbinafine (lactate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Terbinafine <em>lactate</em>
  • HY-14538B

    Others Neurological Disease
    Haloperidol lactate is a potent antipsychotic agent. Haloperidol lactate can be used in acute and chronic schizophrenia and gilles de la tourette's syndrome. Haloperidol lactate has the potential for the research of psychotic disorders .
    Haloperidol <em>lactate</em>
  • HY-B0510C
    Trimethoprim lactate
    5 Publications Verification

    Antifolate Bacterial Antibiotic Infection
    Trimethoprim lactate is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim lactate is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim lactate has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim lactate can inhibit infection of Influenza A virus in chick embryo when combinated with zinc .
    Trimethoprim <em>lactate</em>
  • HY-B0889
    Ethacridine lactate monohydrate
    2 Publications Verification

    Acrinol monohydrate

    Bacterial Infection
    Ethacridine lactate (Acrinol) monohydrate is a widely used antiseptic and abortifacient. Ethacridine lactate monohydrate is effective against Staphylococcus aureus and other gram-positive cocci. Ethacridine lactate monohydrate is also a poly(ADP-ribose) glycohydrolase (PARG) inhibitor .
    Ethacridine <em>lactate</em> monohydrate
  • HY-B2174
    Ethacridine lactate
    2 Publications Verification

    Acrinol

    Bacterial Infection
    Ethacridine lactate (Acrinol) is a widely used antiseptic and abortifacient. Ethacridine lactate is effective against Staphylococcus aureus and other gram-positive cocci. Ethacridine lactate is also a poly(ADP-ribose) glycohydrolase (PARG) inhibitor .
    Ethacridine <em>lactate</em>
  • HY-13204B

    KL 373 lactate

    mAChR Neurological Disease
    Biperiden (KL 373) lactate is an orally active non-selective muscarinic receptor antagonist that competitively binds to M1 muscarinic receptors. Biperiden (KL 373) lactate inhibits acetylcholine and enhances dopamine signaling in the central nervous system. Biperiden (KL 373) lactate has the potential for the research of Parkinson's disease and other related psychiatric disorders .
    Biperiden <em>lactate</em>
  • HY-10207
    Dovitinib lactate
    5+ Cited Publications

    CHIR-258 lactate; TKI-258 lactate

    FLT3 c-Kit FGFR VEGFR PDGFR Cancer
    Dovitinib lactate (TKI258 lactate) is a multi-targeted tyrosine kinase inhibitor with IC50s of 1, 2, 8/9, 10/13/8, 27/210 nM for FLT3, c-Kit, FGFR1/3, VEGFR1/2/3 and PDGFRα/β, respectively .
    Dovitinib <em>lactate</em>
  • HY-B0062

    TKI258 lactate hydrate; CHIR-258 lactate hydrate

    FLT3 c-Kit FGFR VEGFR PDGFR Cancer
    Dovitinib lactate hydrate (TKI258 lactate hydrate) is a multi-targeted tyrosine kinase inhibitor with IC50s of 1, 2, 8/9, 10/13/8, 27/210 nM for FLT3, c-Kit, FGFR1/3, VEGFR1/2/3 and PDGFRα/β, respectively .
    Dovitinib <em>lactate</em> hydrate
  • HY-P2807

    LAD

    Endogenous Metabolite Inflammation/Immunology
    L-Lactate dehydrogenase, Microorganism (LAD) is a redox enzyme. L-Lactate dehydrogenase catalyzes the reduction of pyruvate to L-lactate by NADH in vivo with absolute enantiospecificity .
    L-<em>Lactate</em> dehydrogenase, Microorganism
  • HY-143959S

    Isotope-Labeled Compounds Others
    Fingolimod Mono-lactate-d4 (hydrochloride) is the deuterium labeled Fingolimod Mono-lactate hydrochloride[1].
    Fingolimod Mono-<em>lactate</em>-d4 hydrochloride
  • HY-P2897

    D-LDH

    Lactate Dehydrogenase Others
    D-Lactate dehydrogenase, Microorganism (D-LDH) is an oxidoreductase that uses NAD + or NADP + as an acceptor and acts on the donor CH-OH group, and can catalyze the oxidation of D-lactate to pyruvate. D-Lactate dehydrogenase widely exists in bacteria and fungi, and is often used in biochemical research .
    D-<em>Lactate</em> dehydrogenase, Microorganism
  • HY-12219A
    MSI-1436 lactate
    1 Publications Verification

    Trodusquemine lactate; Aminosterol-1436 lactate

    Phosphatase Endocrinology
    MSI-1436 lactate is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTP1B), with an IC50 of 1 μM, 200-fold preference over TCPTP (IC50 of 224 μM).
    MSI-1436 <em>lactate</em>
  • HY-W040233S1

    Sodium L-lactate-2-d

    Isotope-Labeled Compounds Others
    Sodium L-Lactate-2-d is the deuterium labeled Sodium L-Lactate-2[1].
    Sodium (S)-2-hydroxypropanoate-2-d1
  • HY-16467

    MSI-1256F

    Bacterial Infection Cardiovascular Disease Cancer
    Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity, and used for the treatment of neovascular age-related macular degeneration.
    Squalamine <em>lactate</em>
  • HY-W040233
    Sodium (S)-2-hydroxypropanoate
    5 Publications Verification

    Sodium L-lactate

    Others Others
    Sodium (S)-2-hydroxypropanoate (Sodium L-lactate) is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid .
    Sodium (S)-2-hydroxypropanoate
  • HY-156683

    Lactate Dehydrogenase Metabolic Disease
    CHK-336 (Example 1) is an orally active LDHA inhibitor (IC50<1 nM) that inhibits lactate production in mouse hepatocytes. CHK-336 can be used in the study of hyperoxaluria .
    CHK-336
  • HY-W040233B

    Sodium L-lactate (purity≥90%)

    Others Others
    Sodium (S)-2-hydroxypropanoate (Sodium L-lactate) (purity≥90%) is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid .
    Sodium (S)-2-hydroxypropanoate (purity≥90%)
  • HY-D0713
    7ACC2
    5 Publications Verification

    Monocarboxylate Transporter Mitochondrial Metabolism Cancer
    7ACC2 is a potent monocarboxylate transporter (MCT) inhibitor with an IC50 of 11 nM for inhibition of [ 14C]-lactate influx. 7ACC2 is also a potent inhibitor of mitochondrial pyruvate transport. 7ACC2 is an anticancer agent through inhibition of lactate flux .
    7ACC2
  • HY-131485

    3-APAD

    Lactate Dehydrogenase Metabolic Disease
    3-Acetylpyridine adenine dinucleotide (3-APAD) is an analog of nicotinamide adenine dinucleotide (NAD). 3-Acetylpyridine adenine dinucleotide collaboratively inhibits Lactate Dehydrogenase (LDH) with bisulfite .
    3-Acetylpyridine adenine dinucleotide
  • HY-132606

    DCR-PHXC

    Small Interfering RNA (siRNA) Metabolic Disease
    Nedosiran (DCR-PHXC) is an RNA interference (RNAi) targeting lactate dehydrogenase (LDH). Nedosiran represents an impactful potential therapeutic for primary hyperoxaluria (PH) with end-stage renal disease (ESRD). Nedosiran is a GalNAc-dsRNA conjugate .
    Nedosiran
  • HY-139665

    Monocarboxylate Transporter Cardiovascular Disease
    VB124 is an orally active, potent, and selective MCT4 inhibitor. VB124 can specifically inhibit lactate efflux with IC50s of 8.6 nM and 19 nM for lactate import and export in MDA-MB-231 cells, respectively. VB124 is highly selective for MCT4 over MCT1. VB124 can be used for the research of cardiac hypertrophy, heart failure, and metabolism .
    VB124
  • HY-139319
    LDHA-IN-3
    1 Publications Verification

    Lactate Dehydrogenase Cancer
    LDHA-IN-3, as a selenobenzene compound, is a potent, noncompetitive lactate dehydrogenase (LDHA) inhibitor (IC50=145.2 nM). LDHA-IN-3 can be used for the research of cancer .
    LDHA-IN-3
  • HY-34154

    Others Metabolic Disease
    4-(Dimethylamino)phenol increases the extracellular lactate dehydrogenase (LDH) without markedly affecting gluconeogenesis. 4-(Dimethylamino)phenol cannot decreases the ATP content until the membrane becomes permeable to LDH .
    4-(Dimethylamino)phenol
  • HY-110119

    Lactate Dehydrogenase Apoptosis Others
    Galloflavin potassium is a novel lactate dehydrogenase inhibitor that can be used for the research of cancer. Galloflavin inhibits aerobic glycolysis in PLC/PRF/5 cells and triggers cell death via apoptosis .
    Galloflavin potassium
  • HY-150753

    Oxidative Phosphorylation Lactate Dehydrogenase Cancer
    RS6212 is a specific LDH (lactate dehydrogenase) inhibitor with an IC50 value of 12.03 μM . RS6212 inhibits tumor growth and exhibits potent anticancer activity in multiple cancer cell lines .
    RS6212
  • HY-147216A
    AXKO-0046 dihydrochloride
    2 Publications Verification

    Lactate Dehydrogenase Metabolic Disease Inflammation/Immunology Cancer
    AXKO-0046 dihydrochloride, indole derivative, is an uncompetitive Lactate dehydrogenase B (LDHB) selective inhibitor. AXKO-0046 dihydrochloride has LDHB inhibitory activity with an EC50 value of 42 nM. AXKO-0046 dihydrochloride can be used for the research of cancer metabolism .
    AXKO-0046 dihydrochloride

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

 

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

 

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: