Search Result

Results for "

osteoblasts

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Aryl Hydrocarbon Receptor (1) Autophagy (1) Bacterial (1) Caspase (1) CDK (2) Dipeptidyl Peptidase (1) EBV (1) Endogenous Metabolite (2) Epigenetic Reader Domain (1) ERK (3) Estrogen Receptor/ERR (1) FAK (1) Fluorescent Dye (1) Glucosidase (1) Glutaminase (1) Influenza Virus (1) Integrin (1) Kisspeptin Receptor (2) Macrophage migration inhibitory factor (MIF) (1) mGluR (1) Microtubule/Tubulin (1) MMP (1) NF-κB (1) NOD-like Receptor (NLR) (1) Orexin Receptor (OX Receptor) (2) p38 MAPK (1) Parasite (1) Phosphatase (6) PKA (1) Reactive Oxygen Species (1) RXFP Receptor (1) TGF-beta/Smad (1) Thyroid Hormone Receptor (2) Tyrosinase (1) Wnt (5) β-catenin (4)
By Research Areas:	Cancer (14) Cardiovascular Disease (5) Endocrinology (4) Infection (3) Inflammation/Immunology (8) Metabolic Disease (25) Neurological Disease (4)

By Targets:

Apoptosis (2)

Aryl Hydrocarbon Receptor (1)

Autophagy (1)

Bacterial (1)

Caspase (1)

CDK (2)

Dipeptidyl Peptidase (1)

EBV (1)

Endogenous Metabolite (2)

Epigenetic Reader Domain (1)

ERK (3)

Estrogen Receptor/ERR (1)

FAK (1)

Fluorescent Dye (1)

Glucosidase (1)

Glutaminase (1)

Influenza Virus (1)

Integrin (1)

Kisspeptin Receptor (2)

Macrophage migration inhibitory factor (MIF) (1)

mGluR (1)

Microtubule/Tubulin (1)

MMP (1)

NF-κB (1)

NOD-like Receptor (NLR) (1)

Orexin Receptor (OX Receptor) (2)

p38 MAPK (1)

Parasite (1)

Phosphatase (6)

PKA (1)

Reactive Oxygen Species (1)

RXFP Receptor (1)

TGF-beta/Smad (1)

Thyroid Hormone Receptor (2)

Tyrosinase (1)

Wnt (5)

β-catenin (4)

By Research Areas:

Cancer (14)

Cardiovascular Disease (5)

Endocrinology (4)

Infection (3)

Inflammation/Immunology (8)

Metabolic Disease (25)

Neurological Disease (4)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Peptides

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N8920

Syringetin	Others	Metabolic Disease
Syringetin, a flavonoid derivative, is associated with increased BMP-2 production. Syringetin stimulates osteoblast differentiation at various stages, from maturation to terminally differentiated osteoblasts .

HY-N0008

Orcinol glucoside	Wnt	Neurological Disease
Orcinol glucoside (OG) is an active constituent isolated from Curculigo orchioides, with antidepressant effects. Orcinol glucoside facilitates the shift of MSC fate to osteoblast and prevents adipogenesis via Wnt/β-catenin signaling pathway .

HY-129126

NC9 Cbz-Lys(Acr)-PEG2-dansyl	Glutaminase Microtubule/Tubulin	Others
NC9 (Cbz-Lys(Acr)-PEG2-dansyl) is an irreversible transglutaminase (TG) inhibitor. NC9 inhibits osteoblast differentiation and mineralization. NC9 destabilizes microtubules. NC9 can be used for the research of osteoblast differentiation .

HY-N8837

Trifloroside	MMP	Metabolic Disease
Trifloroside is a secoiridoid glycoside with antioxidant effects. Trifloroside induces osteogenic effects through osteoblast differentiation, adhesion, migration, and mineral apposition. Trifloroside has the potential for osteoblast-mediated bone diseases research .

HY-N2968

Bullatantriol (+)-Bullatantriol	Others	Inflammation/Immunology
Bullatantriol ((+)?-?Bullatantriol) can be isolated from the roots of Homalomena aromatica. Bullatantriol can promote the proliferation and differentiation of osteoblasts. Bullatantriol also inhibits LPS-induced NO production in BV2 cells .

HY-P5929

VnP-16	Integrin FAK	Inflammation/Immunology
VnP-16 can promote bone formation by accelerating osteoblast differentiation and activity through direct interaction with β1 integrin followed by FAK activation .

HY-N7646

Curculigoside B	Others	Others
Curculigoside B, a phenolic glycoside isolated from Curculigo orchioides, enhances the osteoblast proliferation, decreases the area of bone resorption pit, osteoclastic formation and TRAP activity. Antiosteoporotic and antioxidative activities .

HY-N9359

Toddaculin	Apoptosis
Toddaculin is a natural coumarin that can induce differentiation and apoptosis in leukemic cells. Toddaculin suppresses excess osteoclast activity and enhances osteoblast differentiation and mineralization. Toddaculin also exhibits anti-inflammatory activity .

HY-N2351

Paeonoside	Others	Infection Metabolic Disease Inflammation/Immunology
Paeonoside is a bioactive compound identified in P. suffruticosa that promotes wound healing and migration in osteoblast differentiation. Paeonoside has also been reported to have some antidiabetic activity and may prevent sepsis-induced lethality .

HY-124156

KY-02327	Wnt	Metabolic Disease
KY-02327, a metabolically stabilized KY-02061 analog, is a potent Dishevelled (Dvl)-CXXC5 interaction inhibitor. KY-02327 shows an activating effect on the Wnt/β-catenin pathway, resulting in promotion of osteoblast differentiation .

HY-124156A

KY-02327 acetate	Wnt	Metabolic Disease
KY-02327 acetate, a metabolically stabilized KY-02061 analog, is a potent Dishevelled (Dvl)-CXXC5 interaction inhibitor. KY-02327 acetate shows an activating effect on the Wnt/β-catenin pathway, resulting in promotion of osteoblast differentiation .

HY-150186

RXFP2 agonist 2	RXFP Receptor	Metabolic Disease
RXFP2 agonist 2 is a selective，orally active and allosteric RXFP2 agonist with an EC₅₀ value of 0.38 µM. RXFP2 agonist 2 induces osteoblast mineralization. RXFP2 agonist 2 increases bone formation in female mice. RXFP2 agonist 2 has the potential for the research of osteoporosis .

HY-148043

Schnurri-3 inhibitor-1	Others	Others
Schnurri-3 inhibitor-1 is a potent schnurri-3 inhibitor which is an essential regulator of adult bone formation. Schnurri-3 inhibitor-1 can inhibit Shn3 with EF1alpha promoter in osteoblast cell line Shn3FFL with an AC₅₀ value of 2.09 μM. Schnurri-3 inhibitor-1 can be used to research osteoporosis .

HY-128431

Arochlor 1254	Reactive Oxygen Species	Neurological Disease Metabolic Disease
Arochlor 1254 is a polychlorinated biphenyl (PCB) mixture with biphenyl and 54% chlorine. Aroclor 1254 reduced cell viability and induced overproduction of intracellular reactive oxygen species in a dose-dependent manner. Arochlor 1254 exposure reduces calcium homeostasis, osteoblast differentiation and bone formation .

HY-127090

Muramyl dipeptide 2 Publications Verification MDP	p38 MAPK NOD-like Receptor (NLR)	Inflammation/Immunology Cancer
Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramyl dipeptide is an inducer of bone formation through induction of Runx2. Muramyl dipeptide directly enhances osteoblast differentiation by up-regulating Runx2 gene expression through MAPK pathways. Muramyl dipeptide is a NLRP1 agonist .

HY-N2983

Cajanin	Tyrosinase	Others
Cajanin is a potent and orally active anti-melanogenic agent. Cajanin shows antiproliferative activity in MNT1 Cells. Cajanin efficiently decreases the melanin content. Cajanin down-regulates the mRNA and protein expression levels of MITF, tyrosinase, TRP-1 and Dct (TRP-2). Cajanin induces cell cycle arrest at G2/M and S phase. Cajanin stimulates osteoblast proliferation. Cajanin has the potential for the research of human hyperpigmented disorders and menopausal osteoporosis .

HY-150213

ODN BW001

CDK Inflammation/Immunology

ODN BW001 is an oligodeoxynucleotide (ODN). ODN BW001 plays a regulatory role in the proliferation and activation of osteoblast .

ODN BW001	CDK	Inflammation/Immunology
ODN BW001 is an oligodeoxynucleotide (ODN). ODN BW001 plays a regulatory role in the proliferation and activation of osteoblast .

HY-150213A

ODN BW001 sodium	CDK	Inflammation/Immunology
ODN BW001 sodium is an oligodeoxynucleotide (ODN). ODN BW001 sodium plays a regulatory role in the proliferation and activation of osteoblast .

HY-N2247

Guaiacin	Phosphatase	Metabolic Disease
Guaiacin is a arylnaphthalene type lignin isolated from the barks of Machilus thunbergii SIEB. et ZUCC (Lauraceae). Guaiacin significantly increases alkaline phosphatase activity and osteoblast differentiation .

HY-N0432

Astragaloside I Astrasieversianin IV; Cyclosieversioside B	Wnt β-catenin	Metabolic Disease
Astragaloside I, one of the main active ingredients in Astragalus membranaceus, has osteogenic properties. Astragaloside I stimulates osteoblast differentiation through the Wnt/β-catenin signaling pathway .

HY-122808

(-)-Camphoric acid	mGluR	Metabolic Disease
(-)-Camphoric acid is the less active enantiomer of Camphoric acid. Camphoric acid stimulates osteoblast differentiation and induces glutamate receptor expression. Camphoric acid also significantly induced the activation of NF-κB and AP-1 .

HY-N6264

26-Deoxyactein	Aryl Hydrocarbon Receptor ERK	Metabolic Disease
26-Deoxyactein is a constituent isolated from Cimicifuga racemosa, prevents TCDD-induced osteoblasts damage. 26-Deoxyactein inhibits increased AhR, CYP1A1 and ERK levels .

HY-148055A

Wnt/β-catenin agonist 3 hydrochloride	β-catenin	Others
Wnt/β-catenin agonist 3 hydrochloride is a Wnt/β-catenin signalling pathway agonist. Wnt/β-catenin agonist 3 (compound 98) can be used for the research of osteoporosis .

HY-128591

DIPQUO 1 Publications Verification	Phosphatase	Metabolic Disease
DIPQUO is an activator of the bone marker alkaline phosphatase (ALP), with an EC₅₀ of 6.27 μM in C2C12 cells. DIPQUO promotes mouse and human osteoblast differentiation via activation of p38 MAPK-β .

HY-N0123

Aloin Maximum Cited Publications 7 Publications Verification Aloin-A; Barbaloin-A	Others	Cancer
Aloin (Aloin-A; Barbaloin-A) is a natural anti-tumor anthraquinone glycoside with iron chelating activity. Aloin induces the differentiation of MC3T3-E1 cells into osteoblasts through MAPK-mediated Wnt and Bmp signaling pathways. Alkaline phosphatase (ALP) is an early marker of osteoblast differentiation, and the activity of ALP is also enhanced by Aloin. Aloin also reduces brain edema, reduces blood-brain barrier disruption and improves cortical impact injuries. Aloin is used in research into osteoporosis and traumatic brain injury (TBI) .

HY-110063

4-IPP 2 Publications Verification 4-Iodo-6-phenylpyrimidine	Macrophage migration inhibitory factor (MIF)	Metabolic Disease
4-IPP (4-Iodo-6-phenylpyrimidine) is a specific suicide substrate and irreversible inhibitor of macrophage migration inhibitory factor (MIF) .

HY-N0012

Glycitin Glycitein 7-O-β-glucoside	Bacterial	Infection Cancer
Glycitin (Glycitein 7-O-β-glucoside) is a natural isoflavone with antibacterial, antiviral, anticancer, anti-inflammation, anti-aging and estrogenic effects. Glycitin may regulate osteoblasts through TGF-β or AKT signaling pathways in bone marrow stem cells (BMSCs) .

HY-A0119

Nitroprusside disodium dihydrate 5 Publications Verification Sodium nitroprusside dihydrate; Sodium Nitroferricyanide(III) Dihydrate	Autophagy	Cardiovascular Disease Cancer
Nitroprusside disodium dehydrate (Sodium nitroprusside dihydrate) is a vasodilator that available for the research of acute hypertension, heart failure. Nitroprusside disodium dehydrate induces autophagy in glutathione-depleted osteoblasts. Nitroprusside disodium dehydrate acts as a nitric oxide (NO) donor in a rat intestinal ischemia reperfusion model .

HY-150214

ODN MT01	Others	Cancer
ODN MT01 was designed based on human mitochondrial DNA sequences, which is an inhibitory ODN that promotes osteocyte differentiation. ODN MT01 could promote osteoblast maturation and activation in rats, reduce rat alveolar bone absorption caused by periodontitis, regulate the expression levels of osteogenesis-related factors.

HY-150214A

ODN MT 01 sodium	Others	Cancer
ODN MT01 sodium was designed based on human mitochondrial DNA sequences, which is an inhibitory ODN that promotes osteocyte differentiation. ODN MT01 sodium could promote osteoblast maturation and activation in rats, reduce rat alveolar bone absorption caused by periodontitis, regulate the expression levels of osteogenesis-related factors.

HY-133108

Azadirachtin B	EBV Parasite Phosphatase Influenza Virus	Infection Metabolic Disease Inflammation/Immunology Cancer
Azadirachtin B is an limonoid isolated from seed kernels of Azadirachta indica. Azadirachtin B increases alkaline phosphatase (ALP) activity and stimulates osteoblast differentiation. Azadirachtin B is active against the Epstein-Barr virus early antigen (EBV-EA). Azadirachtin B has insecticidal, nematocidal, anticancer, anti-inflammatory, antiviral and osteogenic properties .

HY-110218

CW 008	PKA Epigenetic Reader Domain	Others
CW 008, a derivative of pyrazole-pyridine, is a CREB or PKA pathway agonist. CW 008 also is a stem cell differentiating agent. CW 008 stimulates osteoblast differentiation of human MSCs and increases bone formation in ovariectomized mice. CW008 promotes osteogenesis by activating cAMP/PKA/CREB signaling pathway and inhibiting leptin secretion .

HY-126304

β-Glycerophosphate disodium salt hydrate 4 Publications Verification	Phosphatase Endogenous Metabolite ERK	Metabolic Disease
β-Glycerophosphate disodium salt pentahydrate is a bioactive endogenous metabolite and a phosphatase inhibitor. β-Glycerophosphate disodium salt pentahydrate plays an important role in inducing and maintaining osteoblast differentiation, mineral metabolism and signal transduction, and can be used as a drug carrier to form heat-sensitive hydrogels. β-Glycerophosphate disodium salt hydrate accelerates the calcification of vascular smooth muscle cells .

HY-N6052

(+)-Medicarpin	Estrogen Receptor/ERR	Cancer
(+)-Medicarpin, a pterocarpan, is a type of isoflavonoid isolated from several medicinal plant species with various biological effects, including Sophora japonica, Zollernia paraensis and Platymiscium yucatamun, Machaerium aristulatum, Platymiscium floribundum, and so on. (+)-Medicarpin potently inhibits osteoclastogenesis and promotes bone healing and increases bone mass by osteoblast differentiation with estrogen receptor (ER) β-mediated osteogenic action .

HY-141873

Wnt/β-catenin agonist 2	β-catenin	Others
Wnt/β-catenin agonist 2 is a potent Wnt agonist. Wnt/β-catenin agonist 2 activates Wnt/β-catenin signaling and can be used in the research of diseases related to the signal transduction . (From patent WO2007078113A1, compound 39)

HY-148055

Wnt/β-catenin agonist 3	β-catenin	Cardiovascular Disease
Wnt/β-catenin agonist 3 (compound 98) is a Wnt/β-catenin signalling pathway agonist. Wnt/β-catenin agonist 3 can be used for the research of osteoporosis .

HY-D0886

β-Glycerophosphate disodium salt pentahydrate 4 Publications Verification	Phosphatase Endogenous Metabolite ERK	Metabolic Disease Cancer
β-Glycerophosphate disodium salt pentahydrate is a bioactive endogenous metabolite and a phosphatase inhibitor. β-Glycerophosphate disodium salt pentahydrate plays an important role in inducing and maintaining osteoblast differentiation, mineral metabolism and signal transduction, and can be used as a drug carrier to form heat-sensitive hydrogels. β-Glycerophosphate disodium salt hydrate accelerates the calcification of vascular smooth muscle cells .

HY-N0265

Asperosaponin VI 1 Publications Verification	Caspase Apoptosis	Cardiovascular Disease
Asperosaponin VI, A saponin component from Dipsacus asper, induces osteoblast differentiation through BMP‐2/p38 and ERK1/2 pathway . Asperosaponin Ⅵ inhibits apoptosis in hypoxia-induced cardiomyocyte by increasing the Bcl-2/Bax ratio and decreasing active caspase-3 expression, as well as enhancing of p-Akt and p-CREB .

HY-D2132

Sulfo-Cy5.5-ALN	Fluorescent Dye	Cancer
Sulfo-Cy5.5-ALN is a fluorescent labeled alendronate, which targets bone. Sulfo-Cy5.5-ALN binds to hydroxyapatite and differentiated osteoblasts in vitro. Sulfo-Cy5.5-ALN selectively binds to the mineralized areas of the tumor. Sulfo-Cy5.5-ALN can be used to detect bone overgrowth in prostate bone metastasis .

HY-P1349

Orexin B, rat, mouse Rat orexin B; Orexin B (mouse)	Orexin Receptor (OX Receptor)	Neurological Disease Endocrinology
Orexin B, rat, mouse (Rat orexin B) is an endogenous agonist at Orexin receptor with K_is of 420 and 36 nM for OX1 and OX2, respectively.

HY-P1349A

Orexin B, rat, mouse TFA Rat orexin B TFA; Orexin B (mouse) (TFA)	Orexin Receptor (OX Receptor)	Neurological Disease Endocrinology
Orexin B, rat, mouse (Rat orexin B) TFA is an endogenous orexin receptor agonist. Orexin B, rat, mouse TFA binds and activates two closely related orphan G protein-coupled receptors OX1-R and OX2-R. Orexin B, rat, mouse TFA stimulates food intake and energy expenditure and plays a significant role in sleep-wakefulness regulation .

HY-151520

Wnt/β-catenin agonist 4

Wnt Cancer

Wnt/β-catenin agonist 4 (Derivative 83) is an agonist of Wnt that activates Wnt/β-catenin signal transmission .

Wnt/β-catenin agonist 4	Wnt	Cancer
Wnt/β-catenin agonist 4 (Derivative 83) is an agonist of Wnt that activates Wnt/β-catenin signal transmission .

HY-P0254

Kisspeptin-10, human	Kisspeptin Receptor	Cardiovascular Disease Cancer
Kisspeptin-10, human is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10, human acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role in embryonic kidney development. Kisspeptin-10/GPR54 signaling induces osteoblast differentiation via NFATc4-mediated BMP2 expression .

HY-P0254A

Kisspeptin-10, human TFA	Kisspeptin Receptor	Cardiovascular Disease Cancer
Kisspeptin-10, human TFA is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10, human TFA acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role in embryonic kidney development. Kisspeptin-10/GPR54 signaling induces osteoblast differentiation via NFATc4-mediated BMP2 expression .

HY-N0946

(-)-Pinoresinol 4-O-glucoside (-)-Pinoresinol 4-O-β-D-glucopyranoside	Glucosidase	Metabolic Disease
(-)-Pinoresinol 4-O-glucoside ((-)-Pinoresinol 4-O-β-D-glucopyranoside) is a potent and orally active α-glucosidase inhibitor with an IC₅₀ value of 48.13 µM. (-)-Pinoresinol 4-O-glucoside increases cell migration and early differentiation of pre-osteoblasts. (-)-Pinoresinol 4-O-glucoside increases protein level of BMP2, p-Smad1/5/8, RUNX2. (-)-Pinoresinol 4-O-glucoside attenuates oxidative stress, hyperglycemia and hepatic toxicity. (-)-Pinoresinol 4-O-glucoside has the potential for the research of osteoporosis and periodontal disease .

HY-P1252A

Parathyroid Hormone (1-34), bovine TFA	Thyroid Hormone Receptor	Metabolic Disease
Parathyroid Hormone (1-34), bovine TFA is a potent parathyroid hormone (PTH) receptor agonist. Parathyroid Hormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. Parathyroid Hormone (1-34), bovine can be used for th reseach of osteoporosis .

HY-P1252

Parathyroid Hormone (1-34), bovine 1 Publications Verification	Thyroid Hormone Receptor	Metabolic Disease
Parathyroid Hormone (1-34), bovine is a potent parathyroid hormone (PTH) receptor agonist. Parathyroid Hormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. Parathyroid Hormone (1-34), bovine can be used for th reseach of osteoporosis .

HY-147372

SJ000063181	TGF-beta/Smad	Metabolic Disease
SJ000063181 is a potent BMP signaling activator with an EC₅₀ ≤1 µM. SJ000063181 can be used as chemical probes to interrogate BMP signaling due to it can penetrate zebrafish embryos .

HY-124958

NDMC101	NF-κB Dipeptidyl Peptidase	Metabolic Disease Inflammation/Immunology
NDMC101 is a potent osteoclastogenesis inhibitor and inhibits osteoclast differentiation via down-regulation of NFATc1-modulated gene expression. NDMC101 is similar to the DPP4 substrate and is a significant inhibitor of early T-cell activation via DPP4 inhibition. NDMC101can be used for study of bone disorders, such as rheumatoid arthritis, and synovial inflammation et al .

HY-119539

Limocitrin	Phosphatase	Endocrinology Cancer
Limocitrin is a natural product that can be isolated from the buds of P. acerifolia and P. orientalis. Limocitrin suppresses estradiol-dependent proliferation of MCF7 cells weakly but estradiol-induced AlkP (alkaline phosphatase) expression only marginally .

Cat. No.	Product Name	Target	Research Area

HY-P2633

Dentonin AC-100	Peptides	Metabolic Disease
Dentonin (AC-100) is a synthetic fragment derived from MEPE. Dentonin enhances osteogenesis by promoting osteoprogenitor adhesion and facilitates immature adherent cells survival. Dentonin has no significant effect to mature osteoblasts. Dentonin can be used for the research of phosphate homeostasis and bone metabolism .

HY-P5929

VnP-16	Integrin FAK	Inflammation/Immunology
VnP-16 can promote bone formation by accelerating osteoblast differentiation and activity through direct interaction with β1 integrin followed by FAK activation .

HY-P2633A

Dentonin TFA AC-100 TFA	Peptides	Metabolic Disease
Dentonin TFA (AC-100 TFA) is a synthetic fragment derived from MEPE. Dentonin TFA enhances osteogenesis by promoting osteoprogenitor adhesion and facilitates immature adherent cells survival. Dentonin TFA has no significant effect to mature osteoblasts. Dentonin TFA can be used for the research of phosphate homeostasis and bone metabolism .

HY-P4794

Osteoblast-Adhesive Peptide	Peptides	Others
Osteoblast-Adhesive Peptide is a polypeptide used for chemical modification of biomaterials. Osteoclast Adaptive Peptide increases the adhesion of osteoblasts and has potential applications in dentistry and orthopedics .

HY-P10309

[Nle8,18,Tyr34]-pTH (3-34) amide (human) [Nle8'18,Tyr34]hPTH (3-34) amide	Peptides	Endocrinology
[Nle8,18,Tyr34]-pTH (3-34) amide human ([Nle8,18,Tyr34]hPTH (3-34) amide) is a parathyroid hormone (PTH) analog .

HY-P4587

(Glu13,17,20)-Osteocalcin (1-46) (mouse)	Peptides	Metabolic Disease
(Glu13,17,20)-Osteocalcin (1-46) (mouse) is an analogue of Osteocalcin (1-46). Osteocalcin (1-46) is a osteoblast specific peptide involved in the regulation of energy metabolism .

HY-P4813

Preptin (rat)

Peptides Metabolic Disease

Preptin, an osteogenic peptide product of the pancreatic beta-cell, corresponds to Asp ⁶⁹-Leu ¹⁰² of pro-IGF-II .