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Results for "

sclerostin

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitory Antibodies

6

Recombinant Proteins

Cat. No. Compare Product Name Species Source
  • HY-P78209

    sclerostin; SOST; VBCHsclerosteosis; CDD; DAND6; SOST1; VBCH

    Human HEK293
    SOST proteins act as potent inhibitors of bone growth by effectively inhibiting Wnt signaling and subsequent bone formation. SOST exerts its inhibitory effect by interacting with key Wnt pathway components, including LRP4, LRP5, and LRP6. SOST Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived SOST protein, expressed by HEK293 , with N-His, N-Avi labeled tag. The total length of SOST Protein, Human (Biotinylated, HEK293, His-Avi) is 190 a.a., with molecular weight of 30-40 kDa.
  • HY-P70756

    sclerostin; SOST; UNQ2976; PRO7455; PRO7476

    Human HEK293
    SOST proteins act as potent inhibitors of bone growth by effectively inhibiting Wnt signaling and subsequent bone formation. SOST exerts its inhibitory effect by interacting with key Wnt pathway components, including LRP4, LRP5, and LRP6. SOST Protein, Human (HEK293, His) is the recombinant human-derived SOST protein, expressed by HEK293 , with C-6*His labeled tag. The total length of SOST Protein, Human (HEK293, His) is 190 a.a., with molecular weight of ~30.0 kDa.
  • HY-P70717

    sclerostin; Sost

    Mouse HEK293
    SOST proteins act as potent inhibitors of bone growth by effectively inhibiting Wnt signaling and subsequent bone formation. SOST exerts its inhibitory effect by interacting with key Wnt pathway components, including LRP4, LRP5, and LRP6. SOST Protein, Mouse (HEK293, His) is the recombinant mouse-derived SOST protein, expressed by HEK293 , with C-6*His labeled tag. The total length of SOST Protein, Mouse (HEK293, His) is 188 a.a., with molecular weight of ~32.0 kDa.
  • HY-P78519

    sclerostin; SOST; VBCHsclerosteosis; CDD; DAND6; SOST1; VBCH

    Human HEK293
    SOST protein acts as a potent inhibitor of bone growth by effectively suppressing Wnt signaling and subsequent bone formation. Through interactions with key Wnt pathway components, including LRP4, LRP5, and LRP6, SOST exerts inhibitory effects. Its interaction with LRP4, mediated by the extracellular domain, suppresses Wnt signaling, while interactions with LRP5, specifically through the first two YWTD-EGF repeat domains, contribute to Wnt-mediated signaling inhibition. These interactions emphasize SOST's crucial role in regulating bone development and maintaining bone homeostasis. SOST Protein, Human (HEK293, His-Avi) is the recombinant human-derived SOST protein, expressed by HEK293, with N-His, N-Avi labeled tag. The total length of SOST Protein, Human (HEK293, His-Avi) is 190 a.a., with molecular weight of 28-40 kDa.
  • HY-P700829

    sclerostin; SOST; VBCHsclerosteosis; CDD; DAND6; SOST1; VBCH

    Cynomolgus HEK293
    SOST proteins act as potent inhibitors of bone growth by effectively inhibiting Wnt signaling and subsequent bone formation. SOST exerts its inhibitory effect by interacting with key Wnt pathway components, including LRP4, LRP5, and LRP6. SOST Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived SOST protein, expressed by HEK293 , with C-His labeled tag. The total length of SOST Protein, Cynomolgus (HEK293, His) is 190 a.a., with molecular weight of 30-40 kDa.
  • HY-P71623

    Sost; sclerostin

    Rat E. coli
    SOST protein inhibits bone growth by suppressing Wnt signaling and interacting with LRP4 and LRP5. Its interactions with LRP4 and LRP5 play crucial roles in suppressing Wnt signaling. The involvement of SOST in interactions with LRP6 highlights its regulatory role in bone growth. SOST Protein, Rat (Myc, His) is the recombinant rat-derived SOST protein, expressed by E. coli , with N-His, C-Myc labeled tag. The total length of SOST Protein, Rat (Myc, His) is 185 a.a., with molecular weight of ~28.0 kDa.

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