sea

By Targets:	Adrenergic Receptor (2) Arp2/3 Complex (1) Bacterial (4) Cholinesterase (ChE) (1) Endogenous Metabolite (2) Fluorescent Dye (1) Fungal (2) GnRH Receptor (3) HSV (1) Isotope-Labeled Compounds (1) Lipoxygenase (1) Mitochondrial Metabolism (1) Na+/Ca2+ Exchanger (1) Parasite (4) Potassium Channel (1) Small Interfering RNA (siRNA) (1) Sodium Channel (6)
By Research Areas:	Cancer (9) Cardiovascular Disease (3) Endocrinology (3) Infection (11) Inflammation/Immunology (6) Metabolic Disease (1) Neurological Disease (7)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-15515

SEA0400 Maximum Cited Publications 16 Publications Verification	Na+/Ca2+ Exchanger	Cardiovascular Disease
SEA0400 is a novel and selective inhibitor of the Na ⁺-Ca ²⁺ exchanger (NCX), inhibiting Na ⁺-dependent Ca ²⁺ uptake in cultured neurons, astrocytes, and microglia with IC₅₀s of from 5 to 33 nM.

HY-RS12601

SEA Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SEA Human Pre-designed siRNA Set A contains three designed siRNAs for SEA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SEA Human Pre-designed siRNA Set A SEA Human Pre-designed siRNA Set A

HY-N8195

Quercetin 3-O-sophoroside-7-O-rhamnoside

Others Others

Quercetin 3-O-sophoroside-7-O-rhamnoside is a flavonoid found in sea buckthorn berries .
HY-126594

Echinoside B

Fungal Infection

Echinoside B is a antifungal oligoglycosides isolated from Sea Cucumber Actinopyga echinites .

Quercetin 3-O-sophoroside-7-O-rhamnoside	Others	Others
Quercetin 3-O-sophoroside-7-O-rhamnoside is a flavonoid found in sea buckthorn berries .

Echinoside B	Fungal	Infection
Echinoside B is a antifungal oligoglycosides isolated from Sea Cucumber Actinopyga echinites .

HY-P4898

Anthopleurin-A	Sodium Channel	Cardiovascular Disease
Anthopleurin-A is a soidum channel toxin. Anthopleurin-A is selective for cardiac channels and has cardiotonic effect. Anthopleurin-A can be isolated from the sea anemone .

HY-P4898A

Anthopleurin-A TFA	Sodium Channel	Cardiovascular Disease
Anthopleurin-A TFA is a soidum channel toxin. Anthopleurin-A TFA is selective for cardiac channels and has cardiotonic effect. Anthopleurin-A TFA can be isolated from the sea anemone .

HY-127170

3-Hydroxycoumarin	Lipoxygenase	Others
3-hydroxycoumarin is a potent and redox inhibitor of human 15-LOX-1. 3-hydroxycoumarin is recently demonstrated to protect sea urchin reproductive cells against ultraviolet B damage .

HY-124550

Sarcophine (+)-Sarcophine	Endogenous Metabolite	Neurological Disease
Sarcophine ((+)-Sarcophine) is a potent glycine receptor (GlyR) inhibitor with an IC₅₀ value of 3.9 μM. Sarcophine is a nature product that could be isolated form the Red Sea soft coral Sarcophyton glaucum .

HY-N2225

Isorhamnetin-3-O-sophoroside-7-O-rhamnoside	Others	Infection
Isorhamnetin-3-O-sophoroside-7-O-rhamnoside, the major flavonol glycoside, is isolated from sea buckthorn (Hippophaë rhamnoides). Isorhamnetin-3-O-sophoroside-7-O-rhamnoside has the algicidal activity against the growth of the harmful microalgae .

HY-P3071

ShK toxin Stichodactyla helianthus neurotoxin	Potassium Channel	Inflammation/Immunology
ShK toxin blocks voltage-dependent potassium channel (K_v1.3 channel). ShK toxin can be isolated from the whole body extract of the Caribbean sea anemone (Stichodactylu helianthus). ShK toxin competes with dendrotoxin I and α-dendrotoxin for binding to synaptosomal membranes of rat brain, facilitates acetylcholine release. ShK toxin suppresses K+ currents in cultured rat dorsal root ganglion neurons. ShK toxin also inhibits T lymphocyte proliferation .

HY-119332

3-Keto petromyzonol	Others	Endocrinology
3-Keto petromyzonol, a main component of Sea lamprey male sex pheromones, modulates both synthesis and release of gonadotropin releasing hormone (GnRH), and subsequently, hypothalamic-pituitary-gonadal (HPG) output in immature sea lamprey .

HY-P0245

Speract

Mitochondrial Metabolism Metabolic Disease

Speract, a sea urchin egg peptide that regulates sperm motility, also stimulates sperm mitochondrial metabolism.
HY-P1808

LGnRH-III, lamprey

GnRH Receptor Cancer

LGnRH-III, lamprey, an isoform of GnRH isolated from the sea lamprey, is a weak GnRH agonist with antitumor activities .
HY-N3162

Obtucarbamate B

Others Others

Obtucarbamate B is a carbamate derivative, that can be isolated from the South China Sea gorgonian coral Melitodes squamata Nutting .
HY-N12389

Quellenin

Fungal Infection

Quellenin is an anti-saprolegnia compound. Quellenin can be isolated from deep-sea fungus Aspergillus sp. YK-76

Speract	Mitochondrial Metabolism	Metabolic Disease
Speract, a sea urchin egg peptide that regulates sperm motility, also stimulates sperm mitochondrial metabolism.

LGnRH-III, lamprey	GnRH Receptor	Cancer
LGnRH-III, lamprey, an isoform of GnRH isolated from the sea lamprey, is a weak GnRH agonist with antitumor activities .

Obtucarbamate B	Others	Others
Obtucarbamate B is a carbamate derivative, that can be isolated from the South China Sea gorgonian coral Melitodes squamata Nutting .

Quellenin	Fungal	Infection
Quellenin is an anti-saprolegnia compound. Quellenin can be isolated from deep-sea fungus Aspergillus sp. YK-76

HY-N10262

Piliformic acid	Endogenous Metabolite	Others
Piliformic acid is a fungal metabolite found in the endophytic fungus Xylariasp sp.(No. 2508) from mangrove trees from the coast of the South China Sea .

HY-N7059

Lactobionic acid	Bacterial	Infection
Lactobionic acid is a bionic acid naturally found in the Caspian Sea yogurt and chemically constituted of a gluconic acid bonded to a galactose. Lactobionic acid has antioxidant, antimicrobial, chelating, stabilizer, acidulant, and moisturizing properties .

HY-123063

Petromyzonol 5α-Petromyzonol; 5α-PZ	Others	Others
Petromyzonol (5α-Petromyzonol) is a tetrahydroxy stearol produced by the bile of sea lamprey larvae from the bile acid precursor acetylcholic acid. Petromyzonol sulfate acts as a pheromone and oviposition chemical attractant .

HY-B1207

Urethane 2 Publications Verification Ethyl carbamate; Carbamic acid ethyl ester; Ethylurethane	Bacterial Parasite	Infection Neurological Disease Cancer
Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro .

HY-N4225

Aaptamine	Adrenergic Receptor	Endocrinology Cancer
Aaptamine, a spongean alkaloid isolated from a sea sponge Aaptos aaptos, is a competitive antagonist of α-adrenoceptor and activates the p21 promoter in a p53-independent manner .

HY-P1808R

LGnRH-III, lamprey (Standard)	GnRH Receptor	Cancer
LGnRH-III, lamprey (Standard) is the analytical standard of LGnRH-III, lamprey. This product is intended for research and analytical applications. LGnRH-III, lamprey, an isoform of GnRH isolated from the sea lamprey, is a weak GnRH agonist with antitumor activities .

HY-B1207S

Urethane-d5 Ethyl carbamate-d₅; Carbamic acid ethyl ester-d₅; Ethylurethane-d₅	Bacterial Parasite	Infection Neurological Disease Cancer
Urethane-d₅ is the deuterium labeled Urethane. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro[1].

HY-P1346

APETx2	Sodium Channel	Neurological Disease Inflammation/Immunology
APETx2, a sea anemone peptide from Anthopleura elegantissima, is a selective and reversible ASIC3 inhibitor, with an IC₅₀ of 63 nM. APETx2 directly inhibits the ASIC3 channel by acting at its external side. APETx2 could reverses acid‐induced and inflammatory pain .

HY-P1346A

APETx2 TFA	Sodium Channel	Neurological Disease Inflammation/Immunology
APETx2 TFA, a sea anemone peptide from Anthopleura elegantissima, is a selective and reversible ASIC3 inhibitor, with an IC₅₀ of 63 nM. APETx2 directly inhibits the ASIC3 channel by acting at its external side. APETx2 could reverses acid‐induced and inflammatory pain .

HY-114899

Azamethiphos	Cholinesterase (ChE) Parasite	Neurological Disease
Azamethiphos is an organophosphate insecticide and a neurotoxic agent, causing acetylcholinesterase (AChE) inhibition .

HY-P3673

Lamprey LH-RH I	GnRH Receptor	Endocrinology
Lamprey LH-RH I is a gonadotropin-releasing hormone, elevates plasma steroid levels and stimulates ovulation in the lamprey without biological activity in other animal models .

HY-114899S

Azamethiphos-d6	Isotope-Labeled Compounds	Neurological Disease
Azamethiphos-d₆ is deuterated labeled Azamethiphos. Azamethiphos is an organophosphate insecticide and a neurotoxic agent, causing acetylcholinesterase (AChE) inhibition .

HY-D0914

Fast Green FCF FD&C Green No. 3; Food green 3; C.I. 42053	Fluorescent Dye	Others
Fast Green FCF is a sea green triarylmethane food dye, with absorption maximum ranging from 622 to 626 nm. Fast Green FCF is widely used as a staining agent like quantitative stain for histones at alkaline pH after acid extraction of DNA, and as a protein stain in electrophoresis. Fast Green FCF is carcinogenic and acts as a presynaptic locus by inhibiting the release of neurotransmitters in the nervous system .

HY-N10177

Peniterphenyl A	HSV	Infection
Peniterphenyl A is a natural product obtained from a deep-sea-derived Penicillium sp. Peniterphenyl A inhibits HSV-1/2 virus entry into cells and may block HSV-1/2 infection through direct interaction with virus envelope glycoprotein D to interfere with virus adsorption and membrane fusion. Peniterphenyl A is a promising lead compound against HSV-1/2 .

HY-P1604

ATX-II	Sodium Channel	Inflammation/Immunology
ATX-II is a specific Na ⁺ channel Modulator toxin that can be isolated from the venom of sea anemone (Anemonia sulcata). ATX-II causes delayed inactivation of the Na ⁺

HY-W717530

Retene 7-Isopropyl-1-methylphenanthrene	Others	Others
Retene is widely present in modern and ancient sediments, and can be extracted from fir forest soils, humus coal, continental petroleum source rocks, and deep-sea sediments. Retene can be toxic when exposed to light, and this light-induced toxicity can have lethal and sublethal effects on aquatic organisms. Retene can be used as a model compound to study the interaction between environmental pollutants and ultraviolet rays .

HY-P1604A

ATX-II TFA	Sodium Channel	Inflammation/Immunology
ATX-II TFA is a specific Na ⁺ channel Modulator toxin that can be isolated from the venom of sea anemone (Anemonia sulcata). ATX-II TFA causes delayed inactivation of the Na ⁺

HY-16929

Latrunculin A 5+ Cited Publications LAT-A	Arp2/3 Complex	Cancer
Latrunculin A (LAT-A), found in the red sea sponge Latrunculia magnifica, is a G-actin polymerization inhibitor. Latrunculin A binds to actin monomers and inhibits polymerization of actin with K_ds of 0.1, 0.4, 4.7 μM and 0.19 μM for ATP-actin, ADP-Pi-actin, ADP-actin and G-actin, respectively. Latrunculin A has effective anti-metastatic properties for cancer research. Latrunculin A blocks cell migration .

HY-17592A

Bithionol (sulfoxide) 1 Publications Verification	Parasite	Infection
Bithionol sulfoxide is an anti-infection agent for parasites. Bithionol sulfoxide has mutagenic activity. Bithionol sulfoxide can be used in the research of parasite infection, such as paragonimiasis, flukes andcestodes infection .

HY-115407

Cochliodone A	Bacterial	Infection Cancer
Cochliodone A is an active compound extracted from cultures of the deep-sea derived fungus Chaetomium sp. and has antibacterial and anticancer activity. Cochliodone A is toxic to a variety of bacteria, with MICs of 15.3 μg/mL (V. vulnificus), 32.7 μg/mL (V. rotiferianus), 15.9 μg/mL (S. aureus ATCC 43300), and 16.3 μg/mL (S . aureus CGMCC 1.12409). Cochliodone A also inhibits a variety of cancer cell lines, with IC₅₀s of 28.1 μM (A549), 20.7 μM (HeLa), and 23.2 μM (Hep G2) .

HY-P5158

Conopeptide rho-TIA	Adrenergic Receptor	Others
Conopeptide rho-TIA is a peptide derived from the venom contained in the predatory sea snail Conus tulipa, has highly selective and noncompetitive inhibitor at human α_1B-Adrenergic Receptor. Conopeptide rho-TIA acts a competitive inhibitor at human α_1A-Adrenergic Receptor and α_1D-Adrenergic Receptor. Conopeptide rho-TIA binds to each subtype and may provide useful information for the development of novel α₁-Adrenergic Receptor subtype-selective drugs .

Cat. No.	Product Name	Type

HY-D0914

Fast Green FCF FD&C Green No. 3; Food green 3; C.I. 42053	Dyes
Fast Green FCF is a sea green triarylmethane food dye, with absorption maximum ranging from 622 to 626 nm. Fast Green FCF is widely used as a staining agent like quantitative stain for histones at alkaline pH after acid extraction of DNA, and as a protein stain in electrophoresis. Fast Green FCF is carcinogenic and acts as a presynaptic locus by inhibiting the release of neurotransmitters in the nervous system .

Fast Green FCF

FD&C Green No. 3; Food green 3; C.I. 42053

Dyes

Fast Green FCF is a sea green triarylmethane food dye, with absorption maximum ranging from 622 to 626 nm. Fast Green FCF is widely used as a staining agent like quantitative stain for histones at alkaline pH after acid extraction of DNA, and as a protein stain in electrophoresis. Fast Green FCF is carcinogenic and acts as a presynaptic locus by inhibiting the release of neurotransmitters in the nervous system .

Cat. No.	Product Name	Type

HY-153229

Firefly luciferase mRNA-LNP	Drug Delivery
Firefly luciferase mRNA-LNP is a lipid nanoparticle (LNP) containing Firefly luciferase mRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. Luciferase is commonly used as a bioluminescent reporter gene for gene regulation and function studies. Firefly Luciferase mRNA will express firefly luciferase protein after entering the cells, which is often used for promoter activity detection or dual fluorescent molecular complementation experiments. Common luciferase are firefly luciferase and sea kidney luciferase .

Firefly luciferase mRNA-LNP

Drug Delivery

Firefly luciferase mRNA-LNP is a lipid nanoparticle (LNP) containing Firefly luciferase mRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. Luciferase is commonly used as a bioluminescent reporter gene for gene regulation and function studies. Firefly Luciferase mRNA will express firefly luciferase protein after entering the cells, which is often used for promoter activity detection or dual fluorescent molecular complementation experiments. Common luciferase are firefly luciferase and sea kidney luciferase .

HY-153230

Firefly luciferase circRNA-LNP	Drug Delivery
Firefly luciferase circRNA-LNP is a lipid nanoparticle (LNP) containing Firefly luciferase circRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. Luciferase is commonly used as a bioluminescent reporter gene for gene regulation and function studies. Firefly Luciferase circRNA will express firefly luciferase protein after entering the cells, which is often used for promoter activity detection or dual fluorescent molecular complementation experiments. Common luciferase are firefly luciferase and sea kidney luciferase .

Firefly luciferase circRNA-LNP

Drug Delivery

Firefly luciferase circRNA-LNP is a lipid nanoparticle (LNP) containing Firefly luciferase circRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. Luciferase is commonly used as a bioluminescent reporter gene for gene regulation and function studies. Firefly Luciferase circRNA will express firefly luciferase protein after entering the cells, which is often used for promoter activity detection or dual fluorescent molecular complementation experiments. Common luciferase are firefly luciferase and sea kidney luciferase .

Cat. No.	Product Name	Target	Research Area

HY-P4898A

Anthopleurin-A TFA	Sodium Channel	Cardiovascular Disease
Anthopleurin-A TFA is a soidum channel toxin. Anthopleurin-A TFA is selective for cardiac channels and has cardiotonic effect. Anthopleurin-A TFA can be isolated from the sea anemone .

HY-P1808

LGnRH-III, lamprey

GnRH Receptor Cancer

LGnRH-III, lamprey, an isoform of GnRH isolated from the sea lamprey, is a weak GnRH agonist with antitumor activities .

LGnRH-III, lamprey	GnRH Receptor	Cancer
LGnRH-III, lamprey, an isoform of GnRH isolated from the sea lamprey, is a weak GnRH agonist with antitumor activities .

HY-P4898

Anthopleurin-A	Sodium Channel	Cardiovascular Disease
Anthopleurin-A is a soidum channel toxin. Anthopleurin-A is selective for cardiac channels and has cardiotonic effect. Anthopleurin-A can be isolated from the sea anemone .

HY-P3071

ShK toxin Stichodactyla helianthus neurotoxin	Potassium Channel	Inflammation/Immunology
ShK toxin blocks voltage-dependent potassium channel (K_v1.3 channel). ShK toxin can be isolated from the whole body extract of the Caribbean sea anemone (Stichodactylu helianthus). ShK toxin competes with dendrotoxin I and α-dendrotoxin for binding to synaptosomal membranes of rat brain, facilitates acetylcholine release. ShK toxin suppresses K+ currents in cultured rat dorsal root ganglion neurons. ShK toxin also inhibits T lymphocyte proliferation .

HY-P0245

Speract

Mitochondrial Metabolism Metabolic Disease

Speract, a sea urchin egg peptide that regulates sperm motility, also stimulates sperm mitochondrial metabolism.

HY-P1808R

LGnRH-III, lamprey (Standard)	GnRH Receptor	Cancer
LGnRH-III, lamprey (Standard) is the analytical standard of LGnRH-III, lamprey. This product is intended for research and analytical applications. LGnRH-III, lamprey, an isoform of GnRH isolated from the sea lamprey, is a weak GnRH agonist with antitumor activities .

HY-P1346

APETx2	Sodium Channel	Neurological Disease Inflammation/Immunology
APETx2, a sea anemone peptide from Anthopleura elegantissima, is a selective and reversible ASIC3 inhibitor, with an IC₅₀ of 63 nM. APETx2 directly inhibits the ASIC3 channel by acting at its external side. APETx2 could reverses acid‐induced and inflammatory pain .

HY-P1900

SEB Domain (152-161) 1 Publications Verification	Peptides	Infection
SEB Domain (152-161) is Staphylococcal Enterotoxin B domain amino acid residue 152-161. Staphylococcal enterotoxin B (SEB) is a toxin produced by Staphylococcus aureus. SEB Domain (152-161) is highly conserved and can inhibit transcytosis of multiple staphylococcal enterotoxins, SEA, SEE, and TSST-1 .

HY-P1900A

SEB Domain (152-161) (TFA) 1 Publications Verification	Peptides	Infection
SEB Domain (152-161) TFA is Staphylococcal Enterotoxin B domain amino acid residue 152-161. Staphylococcal enterotoxin B (SEB) is a toxin produced by Staphylococcus aureus. SEB Domain (152-161) TFA is highly conserved and can inhibit transcytosis of multiple staphylococcal enterotoxins, SEA, SEE, and TSST-1 .

HY-P3673

Lamprey LH-RH I	GnRH Receptor	Endocrinology
Lamprey LH-RH I is a gonadotropin-releasing hormone, elevates plasma steroid levels and stimulates ovulation in the lamprey without biological activity in other animal models .

HY-P1604

ATX-II	Sodium Channel	Inflammation/Immunology
ATX-II is a specific Na ⁺ channel Modulator toxin that can be isolated from the venom of sea anemone (Anemonia sulcata). ATX-II causes delayed inactivation of the Na ⁺

HY-P1604A

ATX-II TFA	Sodium Channel	Inflammation/Immunology
ATX-II TFA is a specific Na ⁺ channel Modulator toxin that can be isolated from the venom of sea anemone (Anemonia sulcata). ATX-II TFA causes delayed inactivation of the Na ⁺

HY-P5158

Conopeptide rho-TIA	Adrenergic Receptor	Others
Conopeptide rho-TIA is a peptide derived from the venom contained in the predatory sea snail Conus tulipa, has highly selective and noncompetitive inhibitor at human α_1B-Adrenergic Receptor. Conopeptide rho-TIA acts a competitive inhibitor at human α_1A-Adrenergic Receptor and α_1D-Adrenergic Receptor. Conopeptide rho-TIA binds to each subtype and may provide useful information for the development of novel α₁-Adrenergic Receptor subtype-selective drugs .

Cat. No.	Product Name	Target	Research Area

HY-P99603

Cifurtilimab sea-CD40	Inhibitory Antibodies	Cancer
Cifurtilimab (SEA-CD40) is an agonistic nonfucosylated, human IgG1 monoclonal antibody directed against CD40. Cifurtilimab shows antitumor activities .

HY-P99436

Anatumomab mafenatox ABR-214936	Inhibitory Antibodies	Inflammation/Immunology Cancer
Anatumomab mafenatox (ABR-214936) is a 73 KDa recombinant protein to recognize the tumor-associated antigen 5T4, which is widely expressing in malignancy. Anatumomab mafenatox is between a modified form of SEA and a murine Fab. The main side effects of Anatumomab mafenatox are reported to include fever, low blood pressure, pain, nausea and drowsiness .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-127170

3-Hydroxycoumarin	other families Classification of Application Fields Source classification Other Diseases Coumarins Phenylpropanoids Plants Disease Research Fields	Lipoxygenase
3-hydroxycoumarin is a potent and redox inhibitor of human 15-LOX-1. 3-hydroxycoumarin is recently demonstrated to protect sea urchin reproductive cells against ultraviolet B damage .

HY-N8195

Quercetin 3-O-sophoroside-7-O-rhamnoside	Flavonols Flavonoids Classification of Application Fields Elaeagnaceae Source classification Hippophaë rhamnoides Other Diseases Phenols Polyphenols Plants Disease Research Fields	Others
Quercetin 3-O-sophoroside-7-O-rhamnoside is a flavonoid found in sea buckthorn berries .

HY-126594

Echinoside B	Infection Structural Classification Classification of Application Fields Animals Source classification Marine natural products Other marine organisms Disease Research Fields Saccharides Monosaccharides	Fungal
Echinoside B is a antifungal oligoglycosides isolated from Sea Cucumber Actinopyga echinites .

HY-124550

Sarcophine (+)-Sarcophine	Structural Classification Natural Products Neurological Disease Classification of Application Fields Animals Source classification Marine natural products Other marine organisms Disease Research Fields	Endogenous Metabolite
Sarcophine ((+)-Sarcophine) is a potent glycine receptor (GlyR) inhibitor with an IC₅₀ value of 3.9 μM. Sarcophine is a nature product that could be isolated form the Red Sea soft coral Sarcophyton glaucum .

HY-N2225

Isorhamnetin-3-O-sophoroside-7-O-rhamnoside	Infection Flavonols Structural Classification Flavonoids Classification of Application Fields Elaeagnaceae Source classification Hippophaë rhamnoides Phenols Polyphenols Plants Disease Research Fields	Others
Isorhamnetin-3-O-sophoroside-7-O-rhamnoside, the major flavonol glycoside, is isolated from sea buckthorn (Hippophaë rhamnoides). Isorhamnetin-3-O-sophoroside-7-O-rhamnoside has the algicidal activity against the growth of the harmful microalgae .

HY-119332

3-Keto petromyzonol	Classification of Application Fields Animals Source classification Disease Research Fields Endocrinology Steroids	Others
3-Keto petromyzonol, a main component of Sea lamprey male sex pheromones, modulates both synthesis and release of gonadotropin releasing hormone (GnRH), and subsequently, hypothalamic-pituitary-gonadal (HPG) output in immature sea lamprey .

HY-N3162

Obtucarbamate B	Structural Classification Natural Products Animals Source classification	Others
Obtucarbamate B is a carbamate derivative, that can be isolated from the South China Sea gorgonian coral Melitodes squamata Nutting .

HY-N12389

Quellenin	Structural Classification Monophenols Microorganisms Source classification Phenols	Fungal
Quellenin is an anti-saprolegnia compound. Quellenin can be isolated from deep-sea fungus Aspergillus sp. YK-76

HY-N10262

Piliformic acid	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields	Endogenous Metabolite
Piliformic acid is a fungal metabolite found in the endophytic fungus Xylariasp sp.(No. 2508) from mangrove trees from the coast of the South China Sea .

HY-N7059

Lactobionic acid	Infection Microorganisms Classification of Application Fields Source classification Disease Research Fields Saccharides	Bacterial
Lactobionic acid is a bionic acid naturally found in the Caspian Sea yogurt and chemically constituted of a gluconic acid bonded to a galactose. Lactobionic acid has antioxidant, antimicrobial, chelating, stabilizer, acidulant, and moisturizing properties .

HY-123063

Petromyzonol 5α-Petromyzonol; 5α-PZ	Triterpenes Structural Classification Terpenoids Marine natural products Source classification Marine microorganism	Others
Petromyzonol (5α-Petromyzonol) is a tetrahydroxy stearol produced by the bile of sea lamprey larvae from the bile acid precursor acetylcholic acid. Petromyzonol sulfate acts as a pheromone and oviposition chemical attractant .

HY-B1207

Urethane 2 Publications Verification Ethyl carbamate; Carbamic acid ethyl ester; Ethylurethane	Infection Structural Classification Natural Products Microorganisms Neurological Disease Classification of Application Fields Source classification Disease Research Fields	Bacterial Parasite
Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro .

HY-N4225

Aaptamine	Alkaloids Classification of Application Fields Animals Source classification Marine natural products Quinoline Alkaloids Sponge Disease Research Fields Endocrinology	Adrenergic Receptor
Aaptamine, a spongean alkaloid isolated from a sea sponge Aaptos aaptos, is a competitive antagonist of α-adrenoceptor and activates the p21 promoter in a p53-independent manner .

HY-P1346

APETx2	Structural Classification Natural Products Animals Source classification	Sodium Channel
APETx2, a sea anemone peptide from Anthopleura elegantissima, is a selective and reversible ASIC3 inhibitor, with an IC₅₀ of 63 nM. APETx2 directly inhibits the ASIC3 channel by acting at its external side. APETx2 could reverses acid‐induced and inflammatory pain .

HY-N10177

Peniterphenyl A	Infection Structural Classification Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Disease Research Fields	HSV
Peniterphenyl A is a natural product obtained from a deep-sea-derived Penicillium sp. Peniterphenyl A inhibits HSV-1/2 virus entry into cells and may block HSV-1/2 infection through direct interaction with virus envelope glycoprotein D to interfere with virus adsorption and membrane fusion. Peniterphenyl A is a promising lead compound against HSV-1/2 .

HY-16929

Latrunculin A 5+ Cited Publications LAT-A	Structural Classification Macrolide Antibiotics Animals Classification of Application Fields Antibiotics Marine natural products Source classification Other Diseases Sponge Disease Research Anticancer Disease Research Fields	Arp2/3 Complex
Latrunculin A (LAT-A), found in the red sea sponge Latrunculia magnifica, is a G-actin polymerization inhibitor. Latrunculin A binds to actin monomers and inhibits polymerization of actin with K_ds of 0.1, 0.4, 4.7 μM and 0.19 μM for ATP-actin, ADP-Pi-actin, ADP-actin and G-actin, respectively. Latrunculin A has effective anti-metastatic properties for cancer research. Latrunculin A blocks cell migration .

HY-115407

Cochliodone A	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Cochliodone A is an active compound extracted from cultures of the deep-sea derived fungus Chaetomium sp. and has antibacterial and anticancer activity. Cochliodone A is toxic to a variety of bacteria, with MICs of 15.3 μg/mL (V. vulnificus), 32.7 μg/mL (V. rotiferianus), 15.9 μg/mL (S. aureus ATCC 43300), and 16.3 μg/mL (S . aureus CGMCC 1.12409). Cochliodone A also inhibits a variety of cancer cell lines, with IC₅₀s of 28.1 μM (A549), 20.7 μM (HeLa), and 23.2 μM (Hep G2) .

Species:	Staphylococcus aureus (2)
Tag:	His (2) Myc (1)
Source:	Sf9 insect cells (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P71509

	Enterotoxin type A Protein, S. aureus (His) entAEnterotoxin type A; sea	Staphylococcus aureus	E. coli
	Enterotoxins (ETAs) trigger host immune system activation by binding to major histocompatibility complex class II and T-cell receptor (TCR) molecules. This interaction triggers a cascade of cell activation, cytokine production and migration, primarily mediated by Alphata T cells, affecting lung tissue and airways. Enterotoxin type A Protein, S. aureus (His) is the recombinant Staphylococcus aureus-derived Enterotoxin type A protein, expressed by E. coli , with N-6*His labeled tag. The total length of Enterotoxin type A Protein, S. aureus (His) is 233 a.a., with molecular weight of ~28 kDa.

HY-P72059

	Enterotoxin type A Protein, S. aureus (Baculovirus, His-Myc) entAEnterotoxin type A; sea	Staphylococcus aureus	Sf9 insect cells
	Enterotoxins (ETAs) trigger host immune system activation by binding to major histocompatibility complex class II and T-cell receptor (TCR) molecules. This interaction triggers a cascade of cell activation, cytokine production and migration, primarily mediated by Alphata T cells, affecting lung tissue and airways. Enterotoxin type A Protein, S. aureus (Baculovirus, His-Myc) is the recombinant Staphylococcus aureus-derived Enterotoxin type A protein, expressed by Sf9 insect cells , with N-10*His, C-Myc labeled tag. The total length of Enterotoxin type A Protein, S. aureus (Baculovirus, His-Myc) is 233 a.a., with molecular weight of ~31.0 kDa.

Cat. No.	Product Name	Chemical Structure

HY-B1207S

Urethane-d5
Urethane-d₅ is the deuterium labeled Urethane. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro[1].

HY-114899S

Azamethiphos-d6
Azamethiphos-d₆ is deuterated labeled Azamethiphos. Azamethiphos is an organophosphate insecticide and a neurotoxic agent, causing acetylcholinesterase (AChE) inhibition .

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HY-P80667

	Fascin Antibody 55 kDa actin bundling protein; Actin bundling protein; FAN1; Fascin 1; Fascin; Singed (Drosophila) like (sea urchin fascin homolog like); Fascin homolog 1; Fascin	WB, IHC-F, IHC-P, ICC/IF, FC, IP	Human, Mouse, Rat, Monkey
	Fascin Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 55 kDa, targeting to Fascin. It can be used for WB,IHC-F,IHC-P,ICC/IF,FC,IP assays with tag free, in the background of Human, Mouse, Rat, Monkey.


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Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

sea

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Natural
Products