Search Result
Results for "
sulfides
" in MedChemExpress (MCE) Product Catalog:
3
Biochemical Assay Reagents
3
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W013186S
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Proton Pump
Bacterial
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Inflammation/Immunology
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Lansoprazole sulfide-d4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an active metabolite of the proton pump inhibitor Lansoprazole. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 µM intracellularly and 0.46 µM in broth[1].
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- HY-W076067
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Cuproptosis
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Neurological Disease
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Ammonium tetrathiomolybdate(VI) is a copper chelator and also is a class of sulfide donor. Ammonium tetrathiomolybdate(VI) has neuroprotection effects. Ammonium tetrathiomolybdate(VI) can be used for the research of brain ischemia .
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- HY-D1275
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Fluorescent Dye
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Others
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CAY10731 (compound 3) is a highly selective fluorescent probe for detection of hydrogen sulfide (H2S). CAY10731 is used to monitor exo- and endogenous H2S in both cancer and normal cells. CAY10731 is applied for imaging of H2S in living tissues at variable depths and in nematodes .
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- HY-W103170
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Bacterial
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Others
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1,8-Dichloroanthraquinone, an anthraquinone, is an inhibitor of sulfide production by sulfate-reducing bacteria .
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- HY-W196803
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Propyl Disulfide; DPDS
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Others
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Others
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Dipropyl disulfide is oxidized to dipropyl thiosulfinate (DPDSO) by rat microsomes. Both flavincontaining monooxygenases (FMO) and cytochrome P450 enzymes (CYPs) are involved in dipropyl disulfide oxidation. Dipropyl disulfide forms two metabolites: propylglutathione sulfide conjugate and propylthiol .
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- HY-141776S
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Ufiprazole-d3
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Drug Metabolite
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Others
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Omeprazole sulfide-d3 is the deuterium labeled Omeprazole sulfide. Omeprazole metabolite Omeprazole sulfide (Ufiprazole) is a metabolite of Omeprazole, which is a proton pump inhibitor.
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- HY-B1786S
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cis-Sulindac sulfide-d3
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γ-secretase
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Neurological Disease
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Sulindac sulfide-d3 is deuterium labeled Sulindac sulfide. Sulindac sulfide is a noncompetitive γ-secretase inhibitor, with an IC50 of 20.2 μM for γ42-secretase activity.
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- HY-128447
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- HY-126124
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AP39
2 Publications Verification
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Others
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Cardiovascular Disease
Neurological Disease
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AP39 is a triphenylphosphonium derivatised anethole dithiolethione and mitochondria-targeting hydrogen sulfide (H2S) donor. AP39 increases intracellular H2S levels. AP39 exerts cytoprotective effects and maintains mitochondrial DNA integrity under oxidative stress conditions. AP39 protects against myocardial reperfusion injury in mice model and has the potential for Alzheimer's disease research .
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- HY-B1786A
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γ-secretase
Amyloid-β
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Neurological Disease
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(E/Z)-Sulindac sulfide is a potent γ-secretase modulator (GSM). (E/Z)-Sulindac sulfide selectively reduces Aβ42 production in favor of shorter Aβ species. (E/Z)-Sulindac sulfide can be used for researching Alzheimer’s disease .
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- HY-W003467R
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Proton Pump
Bacterial
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Infection
Inflammation/Immunology
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Rabeprazole Sulfide (Standard) is the analytical standard of Rabeprazole Sulfide. This product is intended for research and analytical applications. Rabeprazole Sulfide is an active metabolite of Rabeprazole. Rabeprazole is a proton pump inhibitor that suppresses gastric acid secretion through an interaction with (H +/K +)-ATPase in gastric parietal cells. Rabeprazole markedly inhibits the motility of H. pylori. Rabeprazole has the potential for various peptic diseases treatment .
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- HY-144439
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Others
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Cardiovascular Disease
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HTS07545 is a potent sulfide:quinone oxidoreductase (SQOR) inhibitor with an IC50 of 30 nM. HTS07545 decrease the rate of breakdown of hydrogen sulfide (H2S). HTS07545 can be used for heart failure research .
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- HY-P2995
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Biochemical Assay Reagents
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Others
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Hemoglobin is a iron-containing protein in red blood cells with oxygen binding properties. Hemoglobin consits of heme, which binds to oxygen. Hemoglobin also transports other gases, such as carbon dioxide, nitric oxide, hydrogen sulfide and sulfide. Hemoglobin absorbs unneeded oxygen in tissues, as an antioxidant .
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- HY-G0006
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Ufiprazole
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Drug Metabolite
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Others
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Omeprazole metabolite Omeprazole sulfide (Ufiprazole) is a metabolite of Omeprazole, which is a proton pump inhibitor.
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- HY-W250123
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Biochemical Assay Reagents
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Others
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Dibutyl sulfide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-B1786
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- HY-109582
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ADT-OH
2 Publications Verification
5-(4-Hydroxyphenyl)-3H-1,2-dithiole-3-thione; ACS 1
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Apoptosis
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Cancer
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ADT-OH is a hydrogen sulfide-releasing donor. ADT-OH induces apoptosis and inhibits the development of melanoma in vivo by upregulating FADD. ADT-OH has the potential for the research of cancer diseases .
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- HY-E70078
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Biochemical Assay Reagents
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Others
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Cystathionine β-synthase is an enzyme that catalyzes the condensation of serine and homocysteine to water and cystathionine. Cystathionine β-synthase is a prominent enzyme for the production of hydrogen sulfide (H2S) .
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- HY-160240
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Others
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Others
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HPI is a HS - fluorescent probe (Ex/Em=280/410 nm). HPI can be used to detect the HS - form of hydrogen sulfide (H2S) gas in environmental water samples .
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- HY-100287
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Prostaglandin Receptor
Phospholipase
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Endocrinology
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2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide is a compound that inhibits stress-induced ulcer and low toxicity, and can maintain the content of phospholipase A2 and prostaglandin E2 in ulcerated rats induced by water immersed restrained stress.
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- HY-W003467
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Proton Pump
Bacterial
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Infection
Inflammation/Immunology
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Rabeprazole Sulfide is an active metabolite of Rabeprazole. Rabeprazole is a proton pump inhibitor that suppresses gastric acid secretion through an interaction with (H +/K +)-ATPase in gastric parietal cells. Rabeprazole markedly inhibits the motility of H. pylori. Rabeprazole has the potential for various peptic diseases treatment .
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- HY-141552
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Others
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Cardiovascular Disease
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FC9402 is a potent and selective sulfide quinone oxidoreductase (SQOR) inhibitor extracted from patent WO 2020/146636 A1. FC9402 attenuates TAC-induced cardiomyocyte hypertrophy and left ventricle (LV) fibrosis. FC9402 can be used for cardiovascular regulation .
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- HY-120425
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Others
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Infection
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Ethiprole is an insecticide.Metabolic sulfones are produced faster than Fipronil (HY-B0822) in CYP3A4-expressing cells and in vivo in mouse brain and liver.Ethiprole's sulfide, sulfoxide, sulfone and desulfinyl derivatives have better biological activity .
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- HY-121955
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FW1256
1 Publications Verification
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NF-κB
Apoptosis
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Cardiovascular Disease
Inflammation/Immunology
Cancer
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FW1256 is a phenyl analogue and a slow-releasing hydrogen sulfide (H2S) donor. FW1256 inhibits NF-κB activity and induces cell apoptosis. FW1256 exerts potent anti-inflammatory effects and has the potential for cancer and cardiovascular disease treatment .
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- HY-D1256
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Fluorescent Dye
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Neurological Disease
Metabolic Disease
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Msr-blue is a first turn-on fluorescent probe for methionine sulfoxide reductase with a more than 100-fold fluorescence increment. Msr-blue is used for monitoring the enzyme activity in live cells (λex=340 nm, λem=440 nm) .
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- HY-134495
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N-Acetylcysteine ethyl ester; NACET
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Reactive Oxygen Species
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Metabolic Disease
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N-Acetyl-L-cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC). N-Acetyl-L-cysteine ethyl ester exhibits enhanced cell permeability, and produce NAC and cysteine. N-Acetyl-L-cysteine ethyl ester increases circulating hydrogen sulfide (H2S) and can be used as an H2S producer. N-Acetyl-L-cysteine ethyl ester has the potential to substitute NAC as a mucolytic agent, and as a GSH-related antioxidant .
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- HY-P2031
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Arp2/3 Complex
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Others
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Phallacidin is a member of the phallotoxin family of mushroom toxins. Phallacidin binds F-actin .
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- HY-106784A
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Others
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Neurological Disease
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(E)-Ajoene is a oxygenated ajoene and organosulfur compound, which can be acquired via allicin decomposing. The polysulfides from garlic can be converted by human red blood cells into hydrogen sulfide (H2S) and allyl glutathione. (E)-Ajoene has been proved to show neuroprotective effects against ischemic damage. (E)-Ajoene is orally active to inhibit lipid peroxidation. (E)-Ajoene increases the number of cresyl violet-positive neurons and decreases the number of reactive gliosis in the CA1 region .
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- HY-112555
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- HY-P0028
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Phalloidin
Maximum Cited Publications
9 Publications Verification
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Fluorescent Dye
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Others
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Phalloidin is a mushroom-derived toxin which can be used to label F-actin of the cytoskeleton with fluorochrome
.
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- HY-P1695
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Ro 09-0198
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Antibiotic
Bacterial
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Infection
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Cinnamycin (Ro 09-0198) is a tetracyclic peptide antibiotic that binds specifically to phosphatidylethanolamine (PE) .
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- HY-P3143
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PD-1/PD-L1
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Cancer
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BMSpep-57 is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC50 of 7.68 nM. BMSpep-57 binds to PD-L1 with Kds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 facilitates T cell function by in creasing IL-2 production in PBMCs .
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- HY-P3143A
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PD-1/PD-L1
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Cancer
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BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC50 of 7.68 nM. BMSpep-57 hydrochloride binds to PD-L1 with Kds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 hydrochloride facilitates T cell function by in creasing IL-2 production in PBMCs .
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- HY-P1726A
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Melanocortin Receptor
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MSG606 TFA is a potent human MC1 receptor antagonist (IC50=17 nM). MSG606 TFA also partial agonist at human MC3 and MC5 receptors (EC50 values are 59 and 1300 nM, respectively). MSG606 TFA exhibits binding affinity for A375 melanoma cells in vitro. MSG606 TFA reverses the induced hyperalgesia in female mice, with no effect in male mice.
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- HY-P1726
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- HY-P0041
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- HY-P0041A
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Cat. No. |
Product Name |
Type |
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- HY-D1275
-
|
Fluorescent Dyes/Probes
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CAY10731 (compound 3) is a highly selective fluorescent probe for detection of hydrogen sulfide (H2S). CAY10731 is used to monitor exo- and endogenous H2S in both cancer and normal cells. CAY10731 is applied for imaging of H2S in living tissues at variable depths and in nematodes .
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- HY-D1256
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Fluorescent Dyes/Probes
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Msr-blue is a first turn-on fluorescent probe for methionine sulfoxide reductase with a more than 100-fold fluorescence increment. Msr-blue is used for monitoring the enzyme activity in live cells (λex=340 nm, λem=440 nm) .
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Cat. No. |
Product Name |
Type |
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- HY-P2995
-
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Native Proteins
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Hemoglobin is a iron-containing protein in red blood cells with oxygen binding properties. Hemoglobin consits of heme, which binds to oxygen. Hemoglobin also transports other gases, such as carbon dioxide, nitric oxide, hydrogen sulfide and sulfide. Hemoglobin absorbs unneeded oxygen in tissues, as an antioxidant .
|
-
- HY-W250123
-
|
Biochemical Assay Reagents
|
Dibutyl sulfide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-E70078
-
|
Biochemical Assay Reagents
|
Cystathionine β-synthase is an enzyme that catalyzes the condensation of serine and homocysteine to water and cystathionine. Cystathionine β-synthase is a prominent enzyme for the production of hydrogen sulfide (H2S) .
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Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P4909
-
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Peptides
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Infection
|
Autoinducing Peptide I is a cyclic octapeptide secreted by Staphylococcus aureus and can be used in vaccine research .
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- HY-P2031
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Arp2/3 Complex
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Others
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Phallacidin is a member of the phallotoxin family of mushroom toxins. Phallacidin binds F-actin .
|
-
- HY-P0028
-
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Fluorescent Dye
|
Others
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Phalloidin is a mushroom-derived toxin which can be used to label F-actin of the cytoskeleton with fluorochrome
.
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- HY-P10014
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- HY-P3143
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PD-1/PD-L1
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Cancer
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BMSpep-57 is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC50 of 7.68 nM. BMSpep-57 binds to PD-L1 with Kds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 facilitates T cell function by in creasing IL-2 production in PBMCs .
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- HY-P3143A
-
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PD-1/PD-L1
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Cancer
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BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC50 of 7.68 nM. BMSpep-57 hydrochloride binds to PD-L1 with Kds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 hydrochloride facilitates T cell function by in creasing IL-2 production in PBMCs .
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- HY-P1726A
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Melanocortin Receptor
|
|
MSG606 TFA is a potent human MC1 receptor antagonist (IC50=17 nM). MSG606 TFA also partial agonist at human MC3 and MC5 receptors (EC50 values are 59 and 1300 nM, respectively). MSG606 TFA exhibits binding affinity for A375 melanoma cells in vitro. MSG606 TFA reverses the induced hyperalgesia in female mice, with no effect in male mice.
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- HY-P0041
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- HY-P0041A
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-W013186S
-
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Lansoprazole sulfide-d4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an active metabolite of the proton pump inhibitor Lansoprazole. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 µM intracellularly and 0.46 µM in broth[1].
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- HY-141776S
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Omeprazole sulfide-d3 is the deuterium labeled Omeprazole sulfide. Omeprazole metabolite Omeprazole sulfide (Ufiprazole) is a metabolite of Omeprazole, which is a proton pump inhibitor.
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- HY-B1786S
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Sulindac sulfide-d3 is deuterium labeled Sulindac sulfide. Sulindac sulfide is a noncompetitive γ-secretase inhibitor, with an IC50 of 20.2 μM for γ42-secretase activity.
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Cat. No. |
Product Name |
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Classification |
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- HY-119323
-
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Azide
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7-Azido-4-methylcoumarin is a fluorescent hydrogen sulfide (H2S) probe. 7-Azido-4-methylcoumarin serves as a highly sensitive assay for cystathionine β-synthase activity .
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