T100-Mut 

T100-Mut is a cell-permeable peptide whose N-terminus is conjugated with a myristoylated group, allowing it to penetrate and localize to the intracellular side of the plasma membrane, thus mimicking the topology of Tmem100-3Q. T100-Mut can alleviate TRPA1-mediated pain^[1].

3597.30

C₁₆₁H₂₇₁N₄₉O₄₂S

{Myr}-Trp-Lys-Val-Arg-Gln-Arg-Asn-Lys-Lys-Val-Gln-Gln-Gln-Glu-Ser-Gln-Thr-Ala-Leu-Val-Val-Asn-Gln-Arg-Cys-Leu-Phe-Ala

{Myr}-WKVRQRNKKVQQQESQTALVVNQRCLFA

CCCCCCCCCCCCCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)CC1=CC=CC=C1)=O)CC(C)C)=O)CS)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)CC(N)=O)=O)C(C)C)=O)C(C)C)=O)CC(C)C)=O)C)=O)[C@@H](C)O)=O)CCC(N)=O)=O)CO)=O)CCC(O)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)C(C)C)=O)CCCCN)=O)CCCCN)=O)CC(N)=O)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)CCCNC(N)=N)=O)C(C)C)=O)CCCCN)=O)CC2=CNC3=CC=CC=C23)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Weng HJ, et al. Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain. Neuron. 2015 Feb 18;85(4):833-46.  [Content Brief]