ZY-2

Cat. No.: HY-D1876: FAQs
Data Sheet Handling Instructions

Molarity Calculator

ZY-2 is a specific fluorescent probe for pyruvate kinase M2 (PKM2). ZY-2 can image in PKM2-positive cells in a time- and concentration-dependent manner. ZY-2 can be used for the detection of cancer cells.

For research use only. We do not sell to patients.

ZY-2 Chemical Structure

Size		Stock
MOQ		Minimum order quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote
Other size		Get quote

Synthetic products have potential research and development risk.

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This product is a controlled substance and not for sale in your territory.

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

765.94

Formula

C₄₀H₄₃N₇O₅S₂

SMILES

CN1C2=C(SC(S(C)=O)=C2)C3=C1C(N(N=C3)CC4=CC(NC(CN5CCN(C6=CC=C(C=C6)/C=C/C7=CC=[N+](CC)C=C7)CC5)=O)=CC=C4)=O.CC([O-])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (130.56 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.3056 mL	6.5279 mL	13.0559 mL
5 mM	0.2611 mL	1.3056 mL	2.6112 mL
10 mM	0.1306 mL	0.6528 mL	1.3056 mL

View the Complete Stock Solution Preparation Table

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Zhang Y, et al. A responsive fluorescent probe for detecting and imaging pyruvate kinase M2 in live cells. Chem Commun (Camb). 2022, 58(45): 6494-6497.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.3056 mL	6.5279 mL	13.0559 mL	32.6396 mL
	5 mM	0.2611 mL	1.3056 mL	2.6112 mL	6.5279 mL
	10 mM	0.1306 mL	0.6528 mL	1.3056 mL	3.2640 mL
	15 mM	0.0870 mL	0.4352 mL	0.8704 mL	2.1760 mL
	20 mM	0.0653 mL	0.3264 mL	0.6528 mL	1.6320 mL
	25 mM	0.0522 mL	0.2611 mL	0.5222 mL	1.3056 mL
	30 mM	0.0435 mL	0.2176 mL	0.4352 mL	1.0880 mL
	40 mM	0.0326 mL	0.1632 mL	0.3264 mL	0.8160 mL
	50 mM	0.0261 mL	0.1306 mL	0.2611 mL	0.6528 mL
	60 mM	0.0218 mL	0.1088 mL	0.2176 mL	0.5440 mL
	80 mM	0.0163 mL	0.0816 mL	0.1632 mL	0.4080 mL
	100 mM	0.0131 mL	0.0653 mL	0.1306 mL	0.3264 mL

ZY-2 Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ZY-2ZY2ZY 2Fluorescent DyecancerInhibitorinhibitorinhibit

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