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Results for "

AMC

" in MedChemExpress (MCE) Product Catalog:

102

Inhibitors & Agonists

28

Fluorescent Dye

107

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D0027
    7-Amino-4-methylcoumarin

    Coumarin 120; AMC

    		 Fluorescent Dye Antibiotic Fungal Infection
    7-Amino-4-methylcoumarin belongs to a group of coumarins. 7-Amino-4-methylcoumarin can be isolated from an endophytic fungus Xylaria sp., has broad antimicrobial activity. 7-Amino-4-methylcoumarin is additionally commonly used as an important laser dye emitting in the blue region, as well as a fluorescent probe enabling analyses of glycoproteins’ monosaccharides and N-linked oligosaccharides. The excitation wavelength and emission wavelength are 351 nm and 430 nm, respectively .
    7-Amino-4-methylcoumarin
  • HY-114568
    AMC-01

    		Eukaryotic Initiation Factor (eIF) Apoptosis Inflammation/Immunology
    AMC-01 is a potent chemical probe that regulates eIF2-α activity. AMC-01 induces protein kinase RNA activation (PKR) kinase and nuclear factor κb (NF-κB). AMC-01 inhibits apoptosis .
    <em>AMC</em>-01
  • HY-28325
    AMC-04

    		Reactive Oxygen Species p38 MAPK Cancer
    AMC-04 is an unfolded protein response (UPR) activator, which activates UPR pathway through ROS and p38 MAPK signaling and induces apoptotic cell death. AMC-04 can be used for cancer research .
    <em>AMC</em>-04
  • HY-143285
    AMC-GlcNAc

    		Fluorescent Dye
    AMC-GlcNAc (compound 1) is a potent fluorogenic probe for detection and characterization of β-hexosaminidase enzyme activity. AMC-GlcNAc enables continuous monitoring by turn-on fluorescence and fluorescence signal is constant over a wide pH range (Ex=325 nm, Em=390 nm). AMC-GlcNAc enables ratiometric fluorescence detection with high sensitivity and low background, which can be used to screen for recombinant dispersin B activity in E. coli cell lysate .
    <em>AMC</em>-GlcNAc
  • HY-120957
    AMC Arachidonoyl Amide

    AMC-AA; 7-Amino-4-methyl coumarin-arachidonamide

    		 Endogenous Metabolite Metabolic Disease
    AMC arachidonoyl amide (AMC-AA) is one of several fatty acid amides which can be used to measure fatty acid amide hydrolase (FAAH) activity.1 FAAH is a relatively unselective enzyme in that it accepts a variety of amide head groups other than the ethanolamine of its nominal endogenous substrate anandamide.2 Exposure of AMC-AA to FAAH activity results in the release of the fluorescent aminomethyl coumarin that absorbs at 360 nm and emits at 465 nm. This allows the fast and convenient measurement of FAAH activity using a simple cuvette or microplate fluorometer.
    <em>AMC</em> Arachidonoyl Amide
  • HY-D0002
    7-Amino-4-methylcoumarin hydrogensulfate

    Coumarin 120 hydrogensulfate; AMC hydrogensulfate

    		 Fluorescent Dye Others
    7-Amino-4-methylcoumarin hydrogensulfate (Coumarin 120 hydrogensulfate; AMC hydrogensulfate) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    7-Amino-4-methylcoumarin hydrogensulfate
  • HY-P2237
    Boc-Leu-Gly-Arg-AMC

    		Amino Acid Derivatives Endocrinology
    Boc-Leu-Gly-Arg-AMC is a fluorogenic AMC substrate for the convertases. Boc-Leu-Gly-Arg-AMC can be used in enzymatic assays .
    Boc-Leu-Gly-Arg-<em>AMC</em>
  • HY-P1003
    Ac-DEVD-AMC
    4 Publications Verification

    		 Fluorescent Dye Others
    Ac-DEVD-AMC is a fluorescent substrate of caspase-3/caspase-7. When treating Ac-DEVD-AMC with cell lysate, Ac-DEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection, with an excitation wavelength of 380 nm and an emission wavelength of 460 nm .
    Ac-DEVD-<em>AMC</em>
  • HY-P3363
    Z-DEVD-AMC

    		Caspase Cancer
    Z-DEVD-AMC is a selective caspase-3 substrate that can be measured by fluorescence spectrometry. AMC can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates .
    Z-DEVD-<em>AMC</em>
  • HY-P10317
    Suc-YVAD-AMC

    		Fluorescent Dye Others
    Suc-YVAD-AMC is used to measure the cysteine proteins of the proteasome.Suc-YVAD-AMC releases fluorescent AMC when cleaved by cysteine proteases to assess the enzymatic activity of the proteasome .
    Suc-YVAD-<em>AMC</em>
  • HY-P1759
    N-CBZ-Phe-Arg-AMC

    Z-FR-AMC

    		 Cathepsin Others
    N-CBZ-Phe-Arg-AMC (Z-FR-AMC) is a cathepsin substrate used in assessment activity of lysosomal cathepsin enzymes .
    N-CBZ-Phe-Arg-<em>AMC</em>
  • HY-P2008
    Boc-Ile-Glu-Gly-Arg-AMC

    IEGR-AMC

    		 Factor Xa Cardiovascular Disease
    Boc-Ile-Glu-Gly-Arg-AMC (IEGR-AMC) is an activated factor X (FXa) specific fluorogenic peptide substrate used for Factor VIII determination .
    Boc-Ile-Glu-Gly-Arg-<em>AMC</em>
  • HY-P2717
    Ac-YVAD-AMC

    		Caspase Infection
    Ac-YVAD-AMC is an inhibitor for caspase. Ac-YVAD-AMC inhibits bacteria-induced cell death of hypersensitive response (HR) cells .
    Ac-YVAD-<em>AMC</em>
  • HY-115391
    Boc-LRR-AMC

    Boc-Leu-Arg-Arg-AMC

    		 Biochemical Assay Reagents Others
    Boc-LRR-AMC (Boc-Leu-Arg-Arg-AMC) is a fluorogenic substrate, which can be utilized for detecting the trypsin-like activity of the 26S proteasome or the 20S proteasome core .
    Boc-LRR-<em>AMC</em>
  • HY-P10082
    Ac-VETD-AMC

    		Caspase Others
    Ac-VETD-AMC is a synthetic peptide substrate for caspase 8. Ac-VETD-AMC also has potential to assess functional activity of recombinant phytaspase .
    Ac-VETD-<em>AMC</em>
  • HY-137164A
    Ala-Ala-Phe-AMC TFA

    		Fluorescent Dye Others
    Ala-Ala-Phe-AMC TFA is the TFA salt form for Ala-Ala-Phe-AMC. Ala-Ala-Phe-AMC TFA is a fluorogenic substrate, which is used to for tripeptidyl peptidase II (TPPII) activity determination .
    Ala-Ala-Phe-<em>AMC</em> TFA
  • HY-D1634A
    Bz-FVR-AMC TFA

    		Cathepsin Others
    Bz-FVR-AMC TFA is a fluorogenic substrate for procathepsin with a kcat/Km value of 1070 mM -1s -1. The high concentration of BZ-FVR-AMC inhibits the substrate .
    Bz-FVR-<em>AMC</em> TFA
  • HY-P10240
    Ac-WVAD-AMC

    		Fluorescent Dye Others
    Ac-WVAD-AMC is a fluorogenic substrate for caspase 1 .
    Ac-WVAD-<em>AMC</em>
  • HY-P4217
    Z-Gly-Pro-Arg-AMC hydrochloride

    		Cathepsin Others
    Z-Gly-Pro-Arg-AMC hydrochloride a fluorescent trypsin and cathepsin K substrate. Z-Gly-Pro-Arg-AMC hydrochloride can be used to determine trypsin and cathepsin K activity .
    Z-Gly-Pro-Arg-<em>AMC</em> hydrochloride
  • HY-129867
    Z-Leu-Leu-Leu-AMC

    Z-LLL-AMC

    		 Proteasome Others
    Z-Leu-Leu-Leu-AMC is a fluorogenic substrate for measuring the chymotrypsin-like protease activity of the 20S proteasome .
    Z-Leu-Leu-Leu-<em>AMC</em>
  • HY-134434
    Z-Arg-Arg-AMC hydrochloride

    		Cathepsin Others
    Z-Arg-Arg-AMC hydrochloride is a selective substrate of cathepsin B .
    Z-Arg-Arg-<em>AMC</em> hydrochloride
  • HY-P3364
    Ac-QPKK(Ac)-AMC

    		Sirtuin Others
    Ac-QPKK(Ac)-AMC is a fluorogenic substrate for sirtuin through sirtuin deacetylation .
    Ac-QPKK(Ac)-<em>AMC</em>
  • HY-134961
    Z-Ala-Arg-Arg-AMC

    Fluorogenic Proteasome Substrate; Z-ARR-AMC

    		 Proteasome Others
    Z-Ala-Arg-Arg-AMC (Fluorogenic Proteasome Substrate) is a fluorogenic substrate for assaying trypsin-like activity of proteasome .
    Z-Ala-Arg-Arg-<em>AMC</em>
  • HY-P10060
    Boc-Val-Gly-Arg-AMC

    		Biochemical Assay Reagents Others
    Boc-Val-Gly-Arg-AMC is a peptide substrate that can be used to study activity of the proteasome .
    Boc-Val-Gly-Arg-<em>AMC</em>
  • HY-P0019A
    Z-Gly-Gly-Arg-AMC acetate
    Maximum Cited Publications
    8 Publications Verification

    		 Fluorescent Dye Others
    Z-Gly-Gly-Arg-AMC acetate is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP).
    Z-Gly-Gly-Arg-<em>AMC</em> acetate
  • HY-P5976
    Suc-Arg-Pro-Phe-His-Leu-Leu-Val-Tyr-AMC

    Renin Substrate I

    		 Renin Others
    Suc-Arg-Pro-Phe-His-Leu-Leu-Val-Tyr-AMC (Renin Substrate I) is a renin substrate
    Suc-Arg-Pro-Phe-His-Leu-Leu-Val-Tyr-<em>AMC</em>
  • HY-P2435
    Bz-Nle-Lys-Arg-Arg-AMC

    		Liposome Cancer
    Bz-Nle-Lys-Arg-Arg-AMC is a liposome to simulate biological phospholipid membrane. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble payloads can be trapped in the internal aqueous space of liposomes, while lipophilic payloads can partition into and become part of the lipid bilayer. Especially for delivering antisense oligonucleotides, it can overcome problems such as inefficient cellular uptake and rapid loss in the body .
    Bz-Nle-Lys-Arg-Arg-<em>AMC</em>
  • HY-137844
    L-Leucine-7-amido-4-methylcoumarin hydrochloride

    Leu-AMC hydrochloride

    		 Fluorescent Dye Others
    L-Leucine-7-amido-4-methylcoumarin (Leu-AMC) hydrochloride is a bright blue fluorogenic peptidyl substrate for LAP3 (leucine aminopeptidase). L-Leucine-7-amido-4-methylcoumarin hydrochloride can be used for leucine aminopeptidase inhibition assays in vitro .
    L-Leucine-7-amido-4-methylcoumarin hydrochloride
  • HY-P2176
    Z-LRGG-AMC

    Z-Leu-Arg-Gly-Gly-AMC

    		 Biochemical Assay Reagents Others
    Z-LRGG-AMC (Z-Leu-Arg-Gly-Gly-AMC) is a fluorescent substrate that hydrolyzes and releases free fluorescent 7-amino-4-methylcoumarin (AMC). Detection wavelength of AMC: Ex/Em=360/460 nm .
    Z-LRGG-<em>AMC</em>
  • HY-P4340A
    Arg-Arg-AMC acetate

    		Cathepsin Others
    Arg-Arg-AMC acetate is the acetate salt form of Arg-Arg-AMC (HY-P4340). Arg-Arg-AMC acetate is a fluorescent substrate for cathepsin B and used in the cathepsin B activity assay .
    Arg-Arg-<em>AMC</em> acetate
  • HY-P10142
    Ac-YEVD-AMC

    		Fluorescent Dye Others
    Ac-YEVD-AMC is a fluorescent substrate of caspase-1/11. Ac-YEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection when treating with cell lysate .
    Ac-YEVD-<em>AMC</em>
  • HY-P4547
    Ac-Trp-Glu-His-Asp-AMC

    AC-WEHD-AMC

    		 Caspase Others
    Ac-Trp-Glu-His-Asp-AMC (AC-WEHD-AMC) is a potent fluorogenic substrate of caspase-1 .
    Ac-Trp-Glu-His-Asp-<em>AMC</em>
  • HY-P4548
    Boc-Arg-Val-Arg-Arg-AMC hydrochloride

    Boc-RVRR-AMC

    		 Furin Others
    Boc-Arg-Val-Arg-Arg-AMC hydrochloride (Boc-RVRR-AMC) is a synthetic fluorogenic substrate that is efficiently cleaved by furin .
    Boc-Arg-Val-Arg-Arg-<em>AMC</em> hydrochloride
  • HY-P4449
    Ac-VRPR-AMC

    		Caspase Cancer
    Ac-VRPR-AMC is a fluorogenic metacaspase substrate. Ac-VRPR-AMC can be used to tests metacaspase activity .
    Ac-VRPR-<em>AMC</em>
  • HY-P4417A
    Ac-IEPD-AMC TFA

    		Fluorescent Dye Others
    Ac-IEPD-AMC TFA is a fluorescent substrate used to measure protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC fluoresces under UV light irradiation and can emit fluorescent signals .
    Ac-IEPD-<em>AMC</em> TFA
  • HY-P3110
    Ac-DNLD-AMC

    		Fluorescent Dye Others
    Ac-WLA-AMC is a fluorogenic substrate of caspase-3. Ac-WLA-AMC is cleaved to release the fluorescent moiety 7-amino-4-methylcoumarin (AMC), which can be used to quantify the β5c subunit activity .
    Ac-DNLD-<em>AMC</em>
  • HY-D1652
    Ac-LEHD-AMC

    		Caspase Others
    Ac-LEHD-AMC is a fluorogenic substrate for caspase-9 (Excitation: 341 nm; Emission: 441 nm). Caspase-9 can induce hydrolysis of Ac-LEHD-AMC, resulting in the release of AMC fluorophore and its fluorescence can be used to quantify caspase-9 activity .
    Ac-LEHD-<em>AMC</em>
  • HY-P10147
    Ac-LDESD-AMC

    		Caspase Cancer
    Ac-LDESD-AMC is a caspase-2 inhibitor. Ac-LDESD-AMC has a peptide sequence of Leu-Asp-Glu-Ser-Asp .
    Ac-LDESD-<em>AMC</em>
  • HY-P1759B
    N-CBZ-Phe-Arg-AMC TFA

    Z-FR-AMC TFA

    		 Cathepsin Others
    N-CBZ-Phe-Arg-AMC (Z-FR-AMC) TFA is a cathepsin substrate used in assessment activity of lysosomal cathepsin enzymes .
    N-CBZ-Phe-Arg-<em>AMC</em> TFA
  • HY-120659
    Gly-Gly-AMC

    		Fluorescent Dye Others
    Gly-Gly-AMC is a fluorogenic peptide substrate. Gly-Gly-AMC can be used to assess bacterial protease activity of P. aeruginosa and S. aureus .
    Gly-Gly-<em>AMC</em>
  • HY-142021
    Z-Leu-Arg-AMC

    		Parasite Infection
    Z-Leu-Arg-AMC is a 4-methylcoumarinyl-7-amide (Amc) leucine derivative with carboxybenzoyl (Z). Z-Leu-Arg-AMC is the active site of cysteine proteinase trypanopain-Tb from Trypanosoma brucei brucei .
    Z-Leu-Arg-<em>AMC</em>
  • HY-134435
    Z-Arg-AMC hydrochloride

    		Fluorescent Dye Others
    Z-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin and papain. Z-Arg-AMC hydrochloride can be used to research activity of trypsin (Ex/Em=355/460 nm) .
    Z-Arg-<em>AMC</em> hydrochloride
  • HY-D1634
    Bz-FVR-AMC

    		Cathepsin Others
    Bz-FVR-AMC is a fluorogenic substrate for procathepsin with a kcat/Km value of 1070 mM -1s -1. The high concentration of BZ-FVR-AMC inhibits the substrate .
    Bz-FVR-<em>AMC</em>
  • HY-D1503
    Glut-Phe-AMC

    		Fluorescent Dye Others
    Glut-Phe-AMC is a fluorescent dye.
    Glut-Phe-<em>AMC</em>
  • HY-D1705
    Ac-ANW-AMC

    		Proteasome Inflammation/Immunology
    Ac-ANW-AMC is a fluorogenic substrate for immunoproteasome. Ac-ANW-AMC can be used to measure β5i activity (Ex=345 nm, Em=445 nm) .
    Ac-ANW-<em>AMC</em>
  • HY-P10144
    Ac-Orn-Phe-Arg-AMC

    		Fluorescent Dye Others
    Ac-Orn-Phe-Arg-AMC is a potent fluorescent substrate of cd–Tryptase and β 1-Tryptase. Ac-Orn-Phe-Arg-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection .
    Ac-Orn-Phe-Arg-<em>AMC</em>
  • HY-145983
    Suc-Gly-Pro-AMC

    		FAP Cancer
    Suc-Gly-Pro-AMC is a fibroblast activation protein (FAP)-specific substrate. Suc-Gly-Pro-AMC can be used to study the activity of FAP .
    Suc-Gly-Pro-<em>AMC</em>
  • HY-W142117
    H-Asp(AMC)-OH

    		Fluorescent Dye Others
    H-Asp(AMC)-OH, a amino acid derivative, is a fluorescent dye. H-Asp(AMC)-OH dose not inhibit glycine transport at a concentration of 0.25 mM .
    H-Asp(<em>AMC</em>)-OH
  • HY-P3362
    Ac-IETD-AMC

    		Fluorescent Dye Others
    Ac-IETD-AMC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. Ac-IETD-AMC is frequently used to measure caspase-8 activity .
    Ac-IETD-<em>AMC</em>
  • HY-P10162
    Ac-DMQD-AMC

    		Caspase Cancer
    Ac-DMQD-AMC is an inhibitor of caspase-3. Ac-DMQD-AMC is an aromatic amine using aminium-based coupling reagent HATU in the presence of 2,4,6-trimethylpyridine (TMP) .
    Ac-DMQD-<em>AMC</em>

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