Search Result
Results for "
OH
" in MedChemExpress (MCE) Product Catalog:
1086
Inhibitors & Agonists
35
Biochemical Assay Reagents
135
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-148245
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Drug-Linker Conjugates for ADC
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Cancer
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OH-Glu-Val-Cit-PAB-MMAE consists a cleavable ADC linker (OH-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE). SuO-Glu-Val-Cit-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-117580
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OH-PRED
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Drug Metabolite
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Inflammation/Immunology
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16α-Hydroxyprednisolone is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid budesonide via cytochrome P450 3A (CYP3A) enzymes .
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- HY-145523
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Liposome
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Others
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OH-Chol is a cationic cholesterol derivative. OH-Chol can be used for siRNA delivery and gene silencing .
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- HY-160581
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Liposome
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Others
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OH-C-Chol is a cationic liposome that serves as a siRNA delivery vehicle. OH-C-Chol (LP-C) and OH-NC-Chol (LP-NC)/siRNA complexes (lipoplexes) showed better performance than NP-C and NP-NC/siRNA complexes (nanocomplexes), respectively. ) greater gene silencing effect .
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- HY-P4071
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Cathelicidin-OH antimicrobial peptide
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Bacterial
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Infection
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OH-CATH is a natural antimicrobial peptide that can be isolated from the venom and tissue of Ophiophagus hannah (King Cobra) .
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-
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- HY-117580S
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OH-PRED-d3
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Drug Metabolite
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Inflammation/Immunology
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16α-Hydroxyprednisolone-d3 is the deuterium labeled 16α-Hydroxyprednisolone. 16α-Hydroxyprednisolone is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid budesonide via cytochrome P450 3A (CYP3A) enzymes[1][2].
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- HY-P4439
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Amino Acid Derivatives
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Neurological Disease
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H-Met-Val-OH is a dipeptide containing free N-terminal methionine. H-Met-Val-OH exhibits activity against cDNA expressing Flavin-containing monooxygenase (FMO) 1 and FMO3. H-Met-Val-OH has potential applications in the growth of neuritis .
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- HY-P4554
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Endogenous Metabolite
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Metabolic Disease
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H-Phe-Arg-OH is a dipeptide containing phenylalanine and arginine. H-Phe-Arg-OH can be separated from Bradykinin (HY-P0206) through Angiotensin-converting enzyme (ACE, HY-P2983). H-Phe-Arg-OH can be used for metabolic research .
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- HY-P4553
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Amino Acid Derivatives
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Others
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H-Met-Pro-OH is a dipeptide containing methionine and proline. H-Met-Pro-OH is a substrate for aminopeptidase P (APP) and skin fibroblast prolidase .
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- HY-P4648
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Bacterial
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Infection
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H-Trp-Trp-Trp-OH is a tripeptide consisting of tryptophan. H-Trp-Trp-Trp-OH has antibacterial activity .
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- HY-P4531
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Opioid Receptor
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Neurological Disease
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H-Ser-Tyr-OH is a dipeptide consisting of glutamic acid, glycine and histidine. H-Ser-Tyr-OH can form a copper(II) complex with copper ions to form a strong free radical scavenging activity. H-Ser-Tyr-OH also increases the intracellular uptake of the delta opioid receptor ligand deltorphin .
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- HY-P4654
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-
-
- HY-P4296
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Amino Acid Derivatives
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Others
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H-Gly-Sar-Sar-OH is an orally active tripeptide. H-Gly-Sar-Sar-OH is transported through PepT1 within Caco-2 cells. H-Gly Sar Sar OH has potential applications in material transportation .
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- HY-P4287
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Amino Acid Derivatives
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Others
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H-Gly-Lys-Gly-OH is a tripeptide containing glycine and lysine. H-Gly-Lys-Gly-OH can be used for the synthesis of casein and soybean protein .
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- HY-P4846
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CXCR
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Inflammation/Immunology
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Ac-Pro-Gly-Pro-OH is an endogenous degradation product of extracellular collagen and can be used as CXCR2 agonist. Ac-Pro-Gly-Pro-OH elicits bactericidal activity and inhibits lung inflammation, reducing immune cell apoptosis. Ac-Pro-Gly-Pro-OH enhances the production of type 1 cytokines (IFN-γ and IL-12) but inhibits the production of proinflammatory cytokines. Ac-Pro-Gly-Pro-OH has the potential for the research of sepsis .
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- HY-P4294
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Amino Acid Derivatives
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Others
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H-Gly-Pro-Gly-OH is a tripeptide containing glycine and proline. H-Gly-Pro-Gly-OH can be used for the synthesis of other polypeptides, such as (Pro Gly Gly)n .
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- HY-P4393
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Aminopeptidase
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Others
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H-Leu-Trp-Met-Arg-OH is a tetrapeptide. H-Leu-Trp-Met-Arg-OH can be used as a substrate for aminopeptidase-mediated hydrolysis studies .
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- HY-P4551
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- HY-P4641
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Angiotensin-converting Enzyme (ACE)
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Cardiovascular Disease
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H-Trp-Phe-OH is a dipeptide consisting of tryptophan and phenylalanine (Trp-Phe). H-Trp-Phe-OH is also an antihypertensive peptide with inhibitory activity on angiotensin-converting enzyme (ACE), dose-dependently increases NO levels, and decreases endothelin-1 (ET-1) levels. H-Trp-Phe-OH (2 mg/kg; subcutaneous injection; 6 injections over 3 days) causes an increase in ovarian weight in female mice .
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- HY-P4437
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- HY-P4420
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- HY-P4431
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Amino Acid Derivatives
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Others
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H-Met-Asp-OH is a dipeptide containing methionine and aspartic acid, which can be used for the synthesis of polypeptides .
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- HY-P4322
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ERK
Akt
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Neurological Disease
Cancer
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H-Ile-Lys-Val-Ala-Val-OH is one of the most potent active sites of laminin-1. H-Ile-Lys-Val-Ala-Val-OH promotes cell adhesion, neurite outgrowth, and tumor growth. H-Ile-Lys-Val-Ala-Val-OH stimulates BMMSC population growth and proliferation by activating MAPK/ERK1/2 and PI3K/Akt signalling pathways .
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- HY-P1350
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Bacterial
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Infection
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H-Lys-Trp-Lys-OH is a small molecule peptide which displays antibacterial and antiviral activities extracted from patent CN 104072579 A, Compound AMP12.
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- HY-W027951
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DMTU
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Reactive Oxygen Species
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Inflammation/Immunology
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N,N'-Dimethylthiourea (DMTU), isolated from Allium sativum, is an orally active scavenger of hydroxyl radical (•OH) and blocks •OH production by activated neutrophils in vitro. N,N'-Dimethylthiourea protects against water-immersion restraint stress (WIRS)-induced gastric mucosal lesions in rats by exerting its antioxidant action including •OH scavenging and anti-inflammatory action .
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- HY-114437
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Z-D-Phe-Phe-Gly-OH; FIP; Virus Replication Inhibitory Peptide
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Influenza Virus
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Infection
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Fusion Inhibitory Peptide (Z-D-Phe-Phe-Gly-OH, FIP, Virus Replication Inhibitory Peptide) is a potent inhibitor of the virus replication, by inhibiting the membrane fusing activity of a viral glycoprotein .
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- HY-W010770
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- HY-D1151
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Reactive Oxygen Species
Fluorescent Dye
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Others
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HKOH-1 is a highly sensitive green fluorescent probe for the specific detection of ·OH in living cells with a maximum excitation wavelength and emission wavelength of 500 nm and 520 nm, respectively .
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- HY-41121
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Boc-Ala-OH
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Amino Acid Derivatives
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Others
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Boc-L-Ala-OH (Boc-Ala-OH) shows excellent affinity with ATP. Boc-L-Ala-OH contains an amino acid moiety, and an acylamide bond like that of the peptide and protein .
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- HY-136164
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Ligands for E3 Ligase
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Cancer
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VH032-OH is the VH032-based VHL ligand. VH032-OH can be connected to the ligand for protein by a linker to form PROTACs .
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- HY-23095
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- HY-W076696
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Ligands for E3 Ligase
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Cancer
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Lenalidomide-4-OH is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-4-OH can be connected to the ligand for protein by a linker to form PROTAC.
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- HY-139540
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Ligands for E3 Ligase
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Cancer
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Pomalidomide-6-OH is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-6-OH can be connected to the ligand for protein by a linker to form PROTAC .
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- HY-W142161
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Fmoc-MeHis(Trt)-OH
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Amino Acid Derivatives
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Others
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Fmoc-N-Me-His(Trt)-OH (Fmoc-MeHis(Trt)-OH) is a is an amino acid derivative containing amino and carboxyl groups. Fmoc-N-Me-His(Trt)-OH for the synthesis of Fmoc-MeHis (Trt) -Leu-OH .
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- HY-156642
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ADC Cytotoxin
Topoisomerase
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Cancer
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(1-OH)-Exatecan is a quinoline ring compound. (1-OH)-Exatecan has substantial antiproliferative effects. (1-OH)-Exatecan can be used for cancer diseases research .
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- HY-120845
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- HY-130165
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- HY-W004066S
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Endogenous Metabolite
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Ac-Ala-OH-d3 is the deuterium labeled Ac-Ala-OH. Ac-Ala-OH is an endogenous metabolite.
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- HY-W004066S1
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- HY-120761
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ADC Linker
PROTAC Linkers
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Cancer
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Amino-PEG10-OH is non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG10-OH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-130298
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ADC Linker
PROTAC Linkers
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Cancer
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Amino-PEG11-OH is non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG11-OH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-147046
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- HY-126918
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PROTAC Linkers
ADC Linker
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Cancer
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THP-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . THP-PEG6-OH is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-W042654
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- HY-141220
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PROTAC Linkers
ADC Linker
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Cancer
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m-PEG12-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . m-PEG12-OH is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-114995
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- HY-151778
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ADC Linker
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Others
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Fmoc-Abg(N3)-OH is a click chemistry reagent containing an azide group. Fmoc-Abg(N3)-OH has the potential to synthesize peptide nucleic acids (PNA) and peptoids.
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- HY-117045
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PROTAC Linkers
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Cancer
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Propargyl-PEG12-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG12-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-130147
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PROTAC Linkers
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Cancer
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Propargyl-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG5-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-130269
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β-NF-CH2-OH
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Ligands for E3 Ligase
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Cancer
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β-Naphthoflavone-CH2-OH (β-NF-CH2-OH) is a ligand for arylhydrocarbon receptor (AhR) E3 ligase. β-Naphthoflavone-CH2-OH can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs (e.g., β-naphthoflavone-JQ1) that recruit the AhR E3 ligase complex by incorporating AhR ligands into chimeric molecules. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins .
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- HY-157194
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Biochemical Assay Reagents
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Inflammation/Immunology
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RL-6-Me-7-OH is a hapten that activates human and mouse MAIT cells (EC50=25µM). RL-6-Me-7-OH can be combined with carrier proteins and used in antigen design. RL-6-Me-7-OH can be used in inflammation and immunity research .
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- HY-126977
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PROTAC Linkers
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Cancer
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Propargyl-PEG9-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG9-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-130374
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PROTAC Linkers
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Cancer
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Propargyl-PEG8-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG8-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-138735
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PROTAC Linkers
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Cancer
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Propargyl-PEG13-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG13-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-117100
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PROTAC Linkers
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Cancer
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Propargyl-PEG14-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG14-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .
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- HY-120976
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Others
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Cancer
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cDEPMPO is a potent anticancer proagent. High concentrations of DEPMPO spin-trap the ·OH radical together with aryl radicals arising from one-electron reduced BTO (benzotriazine 1,4-di-N-oxide) compounds .
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- HY-79131S5
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- HY-132977
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Others
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Others
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BTTAA-OH is a kind of tris(triazolylmethyl)amine compound. BTTAA-OH has the potential for the research of labeling and/or imaging in living system (extracted from patent WO2012021390A1) .
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- HY-P4550
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Endogenous Metabolite
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Metabolic Disease
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H-Hyp-Gly-OH is a dipeptide containing hydroxyproline and glycine. H-Hyp-Gly-OH promotes the growth of mouse primary fibroblasts on collagen gel. H-Hyp-Gly-OH has potential applications in improving skin by ingesting hydrolyzed collagen. H-Hyp-Gly-OH can be used for metabolic research .
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- HY-156908
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Aryl Hydrocarbon Receptor
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Inflammation/Immunology
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3-OH-Kynurenamine is a lateral metabolite in Tryptophan (HY-N0623) metabolism. 3-OH-Kynurenamine induces a concentration-dependent AhR activation, around 6.5 times higher than L-kynurenine (HY-104026). 3-OH-Kynurenamine confers immunosuppressive properties on dendritic cells (DCs). 3-OH-Kynurenamine can be used for psoriasis research .
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- HY-12362G
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ADC Linker
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Cancer
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Val-cit-PAB-OH GMP is a GMP grade Val-cit-PAB-OH (HY-12362). Val-cit-PAB-OH is a degradable ADC linker.
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- HY-130290
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PROTAC Linkers
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Cancer
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Biotin-PEG4-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
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- HY-W040228
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PROTAC Linkers
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Cancer
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BnO-PEG4-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-W042714
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PROTAC Linkers
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Cancer
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BnO-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-139563
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Others
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Others
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Lenalidomide-C10-OH (6a) is an intermediate in the synthesis of INY-03-041 .
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- HY-151694
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ADC Linker
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Others
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H-L-Orn(N3)-OH (hydrochloride) is a click chemistry reagent containing an azide group. H-L-Orn(N3)-OH (hydrochloride) can be used for the research of various biochemical .
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- HY-W040067
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-
- HY-W008487
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-
- HY-W010836
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-
- HY-W010811
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- HY-78843
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- HY-66026
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-
- HY-66025
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- HY-130407
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PROTAC Linkers
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Cancer
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Lipoamido-PEG3-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Lipoamido-PEG3-OH (compound TA-TEG-G2CN) can be used in the formation of a highly stable, dendronized gold nanoparticle (AuNP)-based drug delivery platform .
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- HY-P10173
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Angiotensin-converting Enzyme (ACE)
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Others
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Abz-LFK(Dnp)-OH is an angiotensin I-converting enzyme (ACE) peptide substrate. Abz-LFK(Dnp)-OH is selective for the C domain of ACE. Abz-LFK(Dnp)-OH can be used to assess ACE activity .
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- HY-126917
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PROTAC Linkers
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Cancer
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THP-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-126919
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PROTAC Linkers
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Cancer
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THP-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-130216
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PROTAC Linkers
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Cancer
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THP-PEG3-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-130230
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PROTAC Linkers
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Cancer
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THP-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-117028
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PROTAC Linkers
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Cancer
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Tos-PEG7-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141219
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PROTAC Linkers
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Cancer
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m-PEG11-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
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- HY-141227
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PROTAC Linkers
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Cancer
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THP-PEG11-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141234
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PROTAC Linkers
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Cancer
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HO-PEG13-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141238
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PROTAC Linkers
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Cancer
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HO-PEG24-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141236
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PROTAC Linkers
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Cancer
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HO-PEG20-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141237
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PROTAC Linkers
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Cancer
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HO-PEG21-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-135048
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PROTAC Linkers
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Cancer
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Mal-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-120430
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PROTAC Linkers
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Cancer
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HO-PEG14-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-120724
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PROTAC Linkers
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Cancer
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HO-PEG15-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-130600
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PROTAC Linkers
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Cancer
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HO-PEG17-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-130342
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PROTAC Linkers
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Cancer
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HO-PEG11-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-130512
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PROTAC Linkers
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Cancer
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Br-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W042579
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PROTAC Linkers
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Cancer
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TBDMS-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141337
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PROTAC Linkers
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Cancer
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Lipoamido-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-135142
-
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PROTAC Linkers
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Cancer
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Br-PEG3-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141235
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PROTAC Linkers
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Cancer
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HO-PEG16-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140356
-
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PROTAC Linkers
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Cancer
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Tos-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-135924
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PROTAC Linkers
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Cancer
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Biotin-PEG3-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-135911
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PROTAC Linkers
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Cancer
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Biotin-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-130890
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PROTAC Linkers
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Cancer
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(+)-Biotin-PEG12-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-133287
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PROTAC Linkers
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Cancer
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m-PEG36-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-133300
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PROTAC Linkers
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Cancer
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HO-PEG22-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-133289
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PROTAC Linkers
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Cancer
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m-PEG48-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-134713
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PROTAC Linkers
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Cancer
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Tos-PEG14-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-134743
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PROTAC Linkers
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Cancer
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m-PEG21-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138389
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PROTAC Linkers
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Cancer
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THP-PEG13-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138413
-
|
PROTAC Linkers
|
Cancer
|
THP-PEG10-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138423
-
|
PROTAC Linkers
|
Cancer
|
Acryloyl-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138483
-
|
PROTAC Linkers
|
Cancer
|
THP-PEG9-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W096156
-
|
PROTAC Linkers
|
Cancer
|
I-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W096157
-
|
PROTAC Linkers
|
Cancer
|
I-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W090623
-
|
PROTAC Linkers
|
Cancer
|
Tos-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W096099
-
|
PROTAC Linkers
|
Cancer
|
Nonylbenzene-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W096105
-
|
PROTAC Linkers
|
Cancer
|
Nonylbenzene-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-144081
-
|
PROTAC Linkers
|
Cancer
|
HO-PEG18-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-41121S6
-
-
- HY-79131S4
-
-
- HY-W007720S
-
-
- HY-W007720S1
-
-
- HY-W008371S2
-
-
- HY-W009204S8
-
-
- HY-W013780S3
-
-
- HY-151660
-
|
ADC Linker
|
Others
|
Fmoc-D-Lys(N3)-OH is a click chemistry reagent containing an azide group. Fmoc-D-Lys(N3)-OH can be used for the research of various biochemical .
|
-
- HY-151732
-
|
ADC Linker
|
Others
|
Z-D-Dbu(N3)-OH is a click chemistry reagent containing an azide group. Z-D-Dbu(N3)-OH can be used for the research of various biochemical .
|
-
- HY-130925
-
|
ADC Linker
|
Cancer
|
BCN-PEG4-OH is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG4-OH is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-136432
-
Mc-GGFG-PAB-OH
|
ADC Linker
|
Cancer
|
Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
|
-
- HY-W088147
-
Z-2-Nal-OH
|
Biochemical Assay Reagents
|
Others
|
Z-L-2-Nal-OH (Z-2-Nal-OH) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-153172
-
|
Others
|
Others
|
Phenylbenzothiazole-PEG4-OH (compound 1) can treat spinal cord injury and promote spine formation .
|
-
- HY-I1111S
-
-
- HY-130541
-
|
PROTAC Linkers
|
Cancer
|
Propargyl-PEG2-OH is a PEG-based PROTAC linker can be used in the synthesis of Thalidomide-O-PEG2-propargyl (HY-126458) . Propargyl-PEG2-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W009204S
-
-
- HY-W008371S
-
-
- HY-Y1250S
-
-
- HY-79131S2
-
-
- HY-W009204S6
-
-
- HY-131189
-
|
Ligands for E3 Ligase
|
Cancer
|
N-Boc-SBP-0636457-OH, a ligand for E3 ubiquitin ligase, is used in the recruitment of IAP E3 ligases. N-Boc-SBP-0636457-OH can be connected to the ligand for Bcl-xL by a linker to form PROTAC Bcl-xL degrader-1 (HY-131188).
|
-
- HY-W004066
-
-
- HY-W012340
-
-
- HY-W048209
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Lys(Palmitoyl)-OH is a Fmoc-amino acid with long alkyl chains. Fmoc-Lys(Palmitoyl)-OH can be used for peptide synthesis .
|
-
- HY-W008385S
-
-
- HY-Y1250S3
-
-
- HY-104004
-
Fmoc-Ser-(GalNAc(Ac)3-alpha-D)-OH; Fmoc-Ser[GalNAc(Ac)3-α-D]-OH; Fmoc-Ser(Ac3AcNH-α-Gal)-OH
|
Amino Acid Derivatives
|
Cancer
|
Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH is a agent for cancer.
|
-
- HY-129637
-
|
PROTAC Linkers
ADC Linker
|
Cancer
|
NH2-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . NH2-PEG5-OH is also a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-120258
-
-
- HY-126883
-
-
- HY-129311
-
-
- HY-W007941S1
-
-
- HY-W010975
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
Fmoc-Lys-OH hydrochloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Lys-OH hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-41121S4
-
-
- HY-W010838
-
-
- HY-W142086
-
-
- HY-104004A
-
Fmoc-Ser-(GalNAc(Ac)3-beta-D)-OH; Fmoc-Ser[GalNAc(Ac)3-β-D]-OH; Fmoc-Ser(Ac3AcNH-β-Gal)-OH
|
Amino Acid Derivatives
|
Others
|
Fmoc-Ser(O-β-D-GalNAc(OAc)3)-OH is a serine derivative .
|
-
- HY-W013190
-
-
- HY-W009003
-
-
- HY-W009005
-
-
- HY-W009085
-
-
- HY-W009088
-
-
- HY-W009337
-
-
- HY-23424
-
-
- HY-42065
-
-
- HY-W010793
-
-
- HY-I1107
-
-
- HY-W142023
-
-
- HY-W007720
-
-
- HY-W007842
-
-
- HY-W008176
-
-
- HY-W008233
-
-
- HY-W008696
-
-
- HY-W011000
-
-
- HY-W011081
-
-
- HY-W011423
-
-
- HY-W011703
-
-
- HY-W012137
-
-
- HY-W012437
-
-
- HY-W012446
-
-
- HY-W011359
-
-
- HY-W007931
-
-
- HY-W006093
-
-
- HY-79648
-
-
- HY-79131
-
-
- HY-W009339
-
-
- HY-W009204
-
-
- HY-W009151
-
-
- HY-W013780
-
-
- HY-W013280
-
-
- HY-W142117
-
|
Fluorescent Dye
|
Others
|
H-Asp(AMC)-OH, a amino acid derivative, is a fluorescent dye. H-Asp(AMC)-OH dose not inhibit glycine transport at a concentration of 0.25 mM .
|
-
- HY-W007798S1
-
|
Isotope-Labeled Compounds
|
Others
|
Fmoc-Cys(Trt)-OH-d2 is the deuterium labeled Fmoc-Cys(Trt)-OH. Fmoc-Cys(Trt)-OH is an N-terminal protected cysteine derivative[1].
|
-
- HY-W010589S
-
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
H-Abu-OH-d3 is the deuterium labeled H-Abu-OH. H-Abu-OH, one of the three isomers of aminobutyric acid, is elevated in the plasma of children with with Reye's syndrome, tyrosinemia, homocystinuria, nonketotic hyperglycinemia, and ornithine transcarbamylase deficiency.
|
-
- HY-W010589S1
-
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
|
H-Abu-OH-d2 is the deuterium labeled H-Abu-OH. H-Abu-OH, one of the three isomers of aminobutyric acid, is elevated in the plasma of children with with Reye's syndrome, tyrosinemia, homocystinuria, nonketotic hyperglycinemia, and ornithine transcarbamylase deficiency.
|
-
- HY-W010589S2
-
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
|
H-Abu-OH-d6 is the deuterium labeled H-Abu-OH. H-Abu-OH, one of the three isomers of aminobutyric acid, is elevated in the plasma of children with with Reye's syndrome, tyrosinemia, homocystinuria, nonketotic hyperglycinemia, and ornithine transcarbamylase deficiency.
|
-
- HY-138521
-
|
ADC Linker
|
Cancer
|
Azido-C6-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-C6-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-156849
-
|
ADC Cytotoxin
Topoisomerase
|
Cancer
|
Exatecan-methylacetamide-OH (compound 6) is a Exatecan derivative with anticancer effects. Exatecan-methylacetamide-OH is an ADC cytotoxin that can be used to synthesize Antibody-Drug Conjugates (ADCs) (CN112125915A; compound 6) .
|
-
- HY-133144
-
|
Ligands for E3 Ligase
|
Cancer
|
Lenalidomide-OH is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is used in the recruitment of CRBN protein. Lenalidomide-OH can be connected to the ligand for protein by a linker to form PROTACs, such as the PROTAC BTK degrader SJF620 (HY-133137) .
|
-
- HY-140423
-
|
PROTAC Linkers
|
Cancer
|
Boc-Aminoxy-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130209
-
|
PROTAC Linkers
|
Cancer
|
S-Acetyl-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W007322
-
|
PROTAC Linkers
|
Cancer
|
Boc-NH-PEG1-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135947
-
|
PROTAC Linkers
|
Cancer
|
Boc-NH-PEG11-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-151569
-
|
HDAC
Apoptosis
|
Inflammation/Immunology
|
SAHA-OH is a selective HDAC6 inhibitor (IC50=23 nM), shows a 10- to 47-fold selectivity for HDAC6 compared to HDAC 1, 2, 3, and 8. SAHA-OH shows anti-inflammatory activity, and attenuates macrophage apoptosis .
|
-
- HY-79128
-
Fmoc-L-Lys(Boc)-OH; Fmoc-Lys(Boc)-OH; N-α-(Fmoc)-N-ε-(t-boc)-L-Lysine-OH
|
Amino Acid Derivatives
|
Others
|
Fmoc-L-Lys (Boc)-OH is a lysine derivative .
|
-
- HY-41121S3
-
-
- HY-41121S5
-
-
- HY-W007750S
-
-
- HY-W008072S
-
-
- HY-W011026S
-
-
- HY-W011026S1
-
-
- HY-W012713S
-
-
- HY-W012908S2
-
-
- HY-W015241S
-
-
- HY-W010982
-
-
- HY-134517
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-HoCys(ACM)-OH, a homolog of cysteine, is synthesized from L-methionine. Fmoc-HoCys(ACM)-OH also can be used for the synthesis of solid phase peptide .
|
-
- HY-W048671
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Thr(TBDMS)-OH is a Threonine derivative. Fmoc-Thr(TBDMS)-OH can be used for the preparation of sugar ligand-tethered functional nucleic acid conjugates for targeted research .
|
-
- HY-W010712
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation .
|
-
- HY-I0781
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
Boc-Hyp-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-Hyp-OH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2]
|
-
- HY-W013123
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-D-Phe(4-CF3)-OH is Phenylalanine derivative. Fmoc-D-Phe(4-CF3)-OH can be used for the research of peptide inhibitors of protein-protein interactions .
|
-
- HY-136432A
-
Mc-GGFG-PAB-OH TFA
|
ADC Linker
|
Cancer
|
Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) TFA is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
|
-
- HY-130200
-
|
PROTAC Linkers
|
Cancer
|
NH2-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-151652
-
|
ADC Linker
|
Others
|
Boc-L-Cys(Propargyl)-OH is a click chemistry reagent. Boc-L-Cys(Propargyl)-OH can be used for the research of various biochemical .
|
-
- HY-W090942
-
-
- HY-155495
-
|
Others
|
Inflammation/Immunology
|
(±)-Bupropion-(CH2)3-OH hydrochloride (compound 3) is a hapten useful in the radioimmunoassay of Bupropion (HY-B0403) .
|
-
- HY-151785
-
|
ADC Linker
|
Others
|
H-L-Dbu(N3)-OH is a click chemistry reagent containing an azide group .
|
-
- HY-150970
-
|
Pyroptosis
|
Cancer
|
ICy-OH, an iodinated photosensitizer, is an effective anticancer agent. ICy-OH can be used not only for deep tissue imaging (λex=640 nm,λem=690-740 nm) but also to selectively induce cell death in pancreatic cancer cells via cell pyroptosis pathway .
|
-
- HY-P10172
-
-
- HY-141186
-
|
PROTAC Linkers
|
Cancer
|
TCO-OH is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130449
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
N-Boc-N-bis(PEG4-OH) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-N-bis(PEG4-OH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W009204S3
-
-
- HY-W009204S2
-
-
- HY-41121S
-
-
- HY-W010389S2
-
-
- HY-W010590S1
-
-
- HY-79131S
-
-
- HY-Y0134S
-
-
- HY-123324
-
5-Hydroxy pomalidomide; CC-17368
|
Ligands for E3 Ligase
|
Cancer
|
Pomalidomide-5-OH (5-hydroxy pomalidomide) is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-5-OH can be connected to the ligand for protein by a linker to form PROTAC .
|
-
- HY-W011210
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Pra-OH is a Glycine (HY-Y0966) derivative . Fmoc-Pra-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-Y1636
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis) .
|
-
- HY-W008371
-
-
- HY-W013286
-
-
- HY-Z0438
-
-
- HY-I0931
-
-
- HY-148667
-
-
- HY-137416
-
-
- HY-117079
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
N-Boc-N-bis(PEG2-OH) is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-N-bis(PEG2-OH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-131833A
-
|
ADC Linker
|
Cancer
|
Fmoc-Gly-Gly-D-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Gly-Gly-D-Phe-OH is the D-isomer of Fmoc-Gly-Gly-Phe-OH (HY-131833).
|
-
- HY-131833G
-
|
ADC Linker
|
Cancer
|
Fmoc-Gly-Gly-Phe-OH GMP is a GMP grade Fmoc-Gly-Gly-Phe-OH (HY-131833). Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-151671
-
|
ADC Linker
|
Others
|
Fmoc-L-MeLys(N3)-OH is a click chemistry reagent containing an azide. Fmoc-L-MeLys(N3)-OH is a SPPS building-block for the introduction of N-Me-Lys that can be modified at the N3-group using Click-chemistry . Fmoc-L-MeLys(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-W014405
-
-
- HY-Y1250S5
-
-
- HY-140945
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-Lys (biotin-PEG12)-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W041983
-
-
- HY-W015230
-
-
- HY-W129585
-
-
- HY-W016948
-
-
- HY-W011342
-
-
- HY-W011913
-
-
- HY-W013517
-
-
- HY-W017406
-
-
- HY-W041984
-
-
- HY-151684
-
|
ADC Linker
|
Others
|
Boc-Ser(O-propargyl)-OH is a click chemistry reagent containing an alkynes group. Boc-Ser(O-propargyl)-OH can be used for the research of various biochemical .
|
-
- HY-12362
-
-
- HY-W009006
-
-
- HY-W009124
-
-
- HY-W009211
-
-
- HY-W009258
-
-
- HY-134852
-
-
- HY-W009381
-
-
- HY-W097163
-
-
- HY-30231
-
-
- HY-W015231
-
-
- HY-W141779
-
-
- HY-W016731
-
-
- HY-W010590
-
-
- HY-W010721
-
-
- HY-W010782
-
-
- HY-W010788
-
-
- HY-W141946
-
-
- HY-W005144
-
-
- HY-W005815
-
-
- HY-W141985
-
-
- HY-W024554
-
-
- HY-W025807
-
-
- HY-W007108
-
-
- HY-W007399
-
-
- HY-W007706
-
-
- HY-W007750
-
-
- HY-W007941
-
-
- HY-W008016
-
-
- HY-W008072
-
-
- HY-W008196
-
-
- HY-W039449
-
-
- HY-W008386
-
-
- HY-W041857
-
-
- HY-W008800
-
-
- HY-W008869
-
-
- HY-W008872
-
-
- HY-W041997
-
-
- HY-W008942
-
-
- HY-W008958
-
-
- HY-W008986
-
-
- HY-W008981
-
-
- HY-W008926
-
-
- HY-W008389
-
-
- HY-W008273
-
-
- HY-W008256
-
-
- HY-W008075
-
-
- HY-W010962
-
-
- HY-W010964
-
-
- HY-W010965
-
-
- HY-W011026
-
-
- HY-W011064
-
-
- HY-W011074
-
-
- HY-W011089
-
-
- HY-W053531
-
-
- HY-W011199
-
-
- HY-W011255
-
-
- HY-W011488
-
-
- HY-W011553
-
-
- HY-W011606
-
-
- HY-W011892
-
-
- HY-W011903
-
-
- HY-W011977
-
-
- HY-W012064
-
-
- HY-W012075
-
-
- HY-W012104
-
-
- HY-W012379
-
-
- HY-W012451
-
-
- HY-W012709
-
-
- HY-W012713
-
-
- HY-W013083
-
-
- HY-W013118
-
-
- HY-W013143
-
-
- HY-W011278
-
-
- HY-W013185
-
-
- HY-W011126
-
-
- HY-W013293
-
-
- HY-W013297
-
-
- HY-W013198
-
-
- HY-W013155
-
-
- HY-W013659
-
-
- HY-W013678
-
-
- HY-W010976
-
-
- HY-W008464
-
-
- HY-W041990
-
-
- HY-W040024
-
-
- HY-W007942
-
-
- HY-W022447
-
-
- HY-W002436
-
-
- HY-W002326
-
-
- HY-W010943
-
-
- HY-W010862
-
-
- HY-W010830
-
-
- HY-W010794
-
-
- HY-W010734
-
-
- HY-W018650
-
-
- HY-77757
-
-
- HY-W141815
-
-
- HY-W009841
-
-
- HY-W015241
-
-
- HY-W009412
-
-
- HY-W009329
-
-
- HY-W009119
-
-
- HY-W007798
-
-
- HY-W008022
-
-
- HY-W142115
-
-
- HY-W014329
-
-
- HY-W008021
-
-
- HY-W008867
-
-
- HY-W008908
-
-
- HY-W011778
-
-
- HY-W141821
-
-
- HY-W250992
-
|
ADC Linker
|
Others
|
Boc-L-Lys(N3)-OH CHA is a click chemistry reagent containing an azide .
|
-
- HY-W010712S1
-
|
Isotope-Labeled Compounds
|
Others
|
Fmoc-His(Trt)-OH- 15N3 is the 15N labeled Fmoc-His(Trt)-OH[1]. Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation[2].
|
-
- HY-79125
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
Fmoc-Hyp(Bom)-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Hyp(Bom)-OH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs<
|
-
- HY-118481
-
|
Others
|
Infection
|
H-Pro-Glu-OH is a protein secreted by pathogenic mycobacteria through the Type VII secretion system. H-Pro-Glu-OH targets LipY lipases to the cell Surface via the ESX-5 Pathway .
|
-
- HY-W111226
-
|
Amyloid-β
Amino Acid Derivatives
|
Cardiovascular Disease
|
Fmoc-His(3-Me)OH derives Histidine-associating compounds with biological activity. Fmoc-His(3-Me)OH, with Fmoc-citrulline-OH, Fmoc-His(1-Me)-OH together, forms tri-peptides and shows vasodilating effect with EC50s of 2.7-4.7 mM in 1.0 mM Phenylephrine (PE)-contracted aorta rings. Fmoc-His(3-Me)OH (resin) also makes Methyl-His-Gly-Lys (His(3-Me)-Gly-Lys), thus acts as an [Ca 2+]i inhibitor. Fmoc-His(3-Me)OH methylates NAHIS02, making it unable to block the Alzheimer's Aβ channel .
|
-
- HY-W016647
-
-
- HY-I1111S3
-
-
- HY-151722
-
|
ADC Linker
|
Cancer
|
Boc-D-Orn(N3)-OH (CHA) is a click chemistry reagent containing an azide group.
|
-
- HY-133058
-
|
PROTAC Linkers
|
Cancer
|
m-PEG7-CH2-OH a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-130477
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-Lys (biotin-PEG4)-OH is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135085
-
|
PROTAC Linkers
|
Cancer
|
Thiol-C2-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134675
-
|
PROTAC Linkers
|
Cancer
|
THP-PEG4-C1-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134678
-
|
PROTAC Linkers
|
Cancer
|
Propanol-PEG5-CH2OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134689
-
|
PROTAC Linkers
|
Cancer
|
Propanol-PEG3-CH2OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134690
-
|
PROTAC Linkers
|
Cancer
|
Propanol-PEG4-CH2OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134691
-
|
PROTAC Linkers
|
Cancer
|
Propanol-PEG6-CH2OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W013097
-
|
Amino Acid Derivatives
|
Others
|
Boc-Arg(di-Z)-OH can be used for the synthesis of amino acid. Boc-Arg(di-Z)-OH can be used for the research of inhibitors for processing proteinases. Boc-Arg(di-Z)-OH is coupled via the mixed anhydride (MA) with HGlu(OBzl)-Lys(Z)-Arg(Z,Z)-CH2Cl .
|
-
- HY-161200
-
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
Thalidomide-piperazine-C-azetidine-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-piperazine-C-azetidine-C2-OH can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-161202
-
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
Thalidomide-piperidine-O-piperidine-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-piperidine-O-piperidine-C2-OH can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-151737
-
|
ADC Linker
|
Others
|
Z-L-Dbu(N3)-OH is a click chemistry reagent containing an Azide . Z-L-Dbu(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-W102709
-
-
- HY-W010775
-
-
- HY-W013678A
-
-
- HY-79128S
-
-
- HY-129944
-
|
Phospholipase
|
Inflammation/Immunology
|
MJ33-OH is a metabolite of MJ33. MJ33 is an active-site-directed, specific, competitive, and reversible phospholipase A2 (PLA2) inhibitor. MJ33 blocks the calcium-independent phospholipase A2 (iPLA2) activity of Prdx6 .
|
-
- HY-W011686
-
-
- HY-W002327
-
|
Biochemical Assay Reagents
|
Others
|
Fmoc-Asn(Trt)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Fmoc-Asn(Trt)-OH can be used for synthesis of Fmoc-based solid-phase peptide synthesis .
|
-
- HY-151652A
-
|
ADC Linker
|
Others
|
Boc-L-Cys(Propargyl)-OH (DCHA) is a click chemistry reagent. Boc-L-Cys(Propargyl)-OH (DCHA) can be used for the research of various biochemical .
|
-
- HY-151733
-
|
ADC Linker
|
Others
|
Fmoc-D-Dbu(N3)-OH is a click chemistry reagent containing an Azide . Fmoc-D-Dbu(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-W008385
-
-
- HY-151703
-
|
ADC Linker
|
Others
|
Boc-D-Lys(N3)-OH is a Boc-protected amino acid derivative, can be used as a click chemistry reagent and an intermediate for synthesis of linkers .
|
-
- HY-131092
-
|
Others
|
Others
|
H-Asn-Arg-OH is used for the solid-phase peptide synthesis.
|
-
- HY-W048830
-
-
- HY-W010895
-
-
- HY-W008353
-
-
- HY-W008633
-
-
- HY-W011321
-
-
- HY-W013162
-
-
- HY-W010893
-
-
- HY-W009762
-
-
- HY-W017150
-
-
- HY-W011020
-
-
- HY-W008379
-
-
- HY-109502S
-
|
Isotope-Labeled Compounds
|
Neurological Disease
|
10-OH-NBP-d4 is deuterium labeled 10-OH-NBP. 10-OH-NBP is a Butylphthalide (3-n-Butylphthalide; NBP; HY-B0647) hydroxylated metabolite and can penetrates the blood-brain barrier (BBB). Butylphthalide exerts neuroprotective effects and has potential for cerebral ischemia research[1].
|
-
- HY-W007035
-
-
- HY-41121S2
-
-
- HY-141186A
-
|
PROTAC Linkers
|
Cancer
|
(R)-TCO-OH is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W096127
-
|
ADC Linker
|
Cancer
|
Biotin-sar-oh is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-I1112
-
-
- HY-W041987
-
-
- HY-W141986
-
-
- HY-W010732
-
-
- HY-W048825
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Ala-Ala-OH (3) is a self-assemble fluorenylmethoxycarbonyl-dipeptide, which is a smaller amphiphilic building blocks consists dipeptides linked to fluore nylmethoxycarbonyl (Fmoc). Fmoc-Ala-Ala-OH can be used as scaffold materials in 3D cell culture .
|
-
- HY-W008395
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-D-Pra-OH is a Glycine (HY-Y0966) derivative . Fmoc-D-Pra-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130889
-
(+)-Biotin-PEG10-alcOHol
|
PROTAC Linkers
|
Cancer
|
(+)-Biotin-PEG10-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W141817
-
-
- HY-W009320
-
-
- HY-W004098
-
-
- HY-W009321
-
-
- HY-151668
-
|
ADC Linker
|
Others
|
Z-L-Aha-OH is a click chemistry reagent containing azide group .
|
-
- HY-151723
-
|
ADC Linker
|
Others
|
H-D-Aha-OH (hydrochloride) is a click chemistry reagent containing an azide group.
|
-
- HY-Y1250S2
-
-
- HY-151709
-
|
ADC Linker
|
Others
|
N3-L-Cit-OH is a click chemistry reagent containing an azide group. N3-L-Cit-OH can be used to construct peptidomimetic ADC linkers using Click-chemistry .
|
-
- HY-140808
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG3-C3-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-C3-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-138471
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG2-C6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG2-C6-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-151718
-
|
ADC Linker
|
Others
|
Boc-L-Tyr(PEG(3)-N3)-OH is a click chemistry agent containing azide.
|
-
- HY-128487
-
G3335
|
PPAR
|
Metabolic Disease
|
H-Trp-Glu-OH is a selective, reversible and cell-permeable PPARγ with a Kd of ~8 µM. H-Trp-Glu-OH might be developed as a possible lead compound in diabetes research .
|
-
- HY-157760
-
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
(S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-OH can serve as a Cereblon ligand to recruit CRBN proteins and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-161184
-
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
Deoxy-thalidomide-piperidine-C-piperazine-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Deoxy-thalidomide-piperidine-C-piperazine-C2-OH can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-161199
-
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
Thalidomide-azetidine-pyrrolidine-C-piperidine-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-azetidine-pyrrolidine-C-piperidine-C2-OH can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-140593
-
|
PROTAC Linkers
|
Cancer
|
m-PEG3-S-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134737
-
|
PROTAC Linkers
|
Cancer
|
Boc-NH-PEG1-C5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-161125
-
|
Others
|
Others
|
(+)-JQ1-OH is the major metabolite of (+)-JQ1(HY-13030). (+)-JQ-1 (JQ1) is a potent, specific, and reversible BET bromodomain inhibitor, with IC50s of 77 and 33 nM for the first and second bromodomain (BRD4(1/2)). (+)-JQ-1 also activates autophagy .
|
-
- HY-W092109
-
-
- HY-W009260
-
-
- HY-W098060
-
-
- HY-23053
-
-
- HY-W015233
-
-
- HY-W015926
-
-
- HY-66024
-
-
- HY-W018366
-
-
- HY-W010714
-
-
- HY-W010888
-
-
- HY-W010924
-
-
- HY-W004083
-
-
- HY-W022444
-
-
- HY-W008156
-
-
- HY-W008359
-
-
- HY-W008495
-
-
- HY-W041986
-
-
- HY-W008866
-
-
- HY-W008887
-
-
- HY-Y1844
-
-
- HY-W043473
-
-
- HY-W008426
-
-
- HY-W050803
-
-
- HY-W051350
-
-
- HY-W062304
-
-
- HY-W011444
-
-
- HY-W012138
-
-
- HY-W012872
-
-
- HY-W013048
-
-
- HY-W013144
-
-
- HY-W011279
-
-
- HY-W013300
-
-
- HY-W053550
-
-
- HY-W013210
-
-
- HY-W051351
-
-
- HY-W042000
-
-
- HY-W041985
-
-
- HY-W013850
-
-
- HY-W014048
-
-
- HY-W022446
-
-
- HY-W022227
-
-
- HY-W010724
-
-
- HY-W010698
-
-
- HY-W140794
-
-
- HY-W009534
-
-
- HY-W016887
-
-
- HY-131095
-
-
- HY-W048332
-
-
- HY-77635
-
-
- HY-W016075
-
-
- HY-W005759
-
-
- HY-W008560
-
-
- HY-W050785
-
-
- HY-W011832
-
-
- HY-W013968
-
-
- HY-W018717
-
-
- HY-W010249
-
-
- HY-W013906
-
-
- HY-W008530
-
-
- HY-W009229
-
-
- HY-48394A
-
|
Others
|
Others
|
Bis-S-C2-N(N-Me)-C2-OH (dihydrochloride) is an active compound. Bis-S-C2-N(N-Me)-C2-OH (dihydrochloride) can be used for various biochemical studies.
|
-
- HY-151693A
-
|
ADC Linker
|
Others
|
H-L-Tyr(2-azidoethyl)-OH is a unnatural Tyrosine derivative. H-L-Tyr(2-azidoethyl)-OH is a click chemistry reagent containing an azide group .
|
-
- HY-151693
-
|
ADC Linker
|
Others
|
H-L-Tyr(2-azidoethyl)-OH hydrochloride is a unnatural Tyrosine derivative. H-L-Tyr(2-azidoethyl)-OH hydrochloride is a click chemistry reagent containing an azide group .
|
-
- HY-W008452
-
|
Endogenous Metabolite
|
Metabolic Disease
|
H-Tyr(3-I)-OH is a potent and effective tyrosine hydroxylase inhibitor. H-Tyr(3-I)-OH is an intermediate in the production of thyroid hormones and has a role as a human or mouse metabolite .
|
-
- HY-130935
-
|
ADC Linker
|
Cancer
|
DBCO-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Val-Cit-OH is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-W004697
-
|
PROTAC Linkers
|
Cancer
|
Boc-GABA-OH is a PROTAC linker which can be used to synthesis UNC6852, an EED-targeted PROTAC .
|
-
- HY-W009338
-
-
- HY-19821
-
-
- HY-W142062
-
|
Amino Acid Derivatives
|
Others
|
cis-Fmoc-Pro(4-N3)-OH is a proline derivative . cis-Fmoc-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-151675
-
|
ADC Linker
|
Others
|
H-L-Tyr(3-N3)-OH is a click chemistry reagent containing an azide . H-L-Tyr(3-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-129944A
-
|
Phospholipase
|
Inflammation/Immunology
|
MJ33-OH lithium is a metabolite of MJ33. MJ33 is an active-site-directed, specific, competitive, and reversible phospholipase A2 (PLA2) inhibitor. MJ33 blocks the calcium-independent phospholipase A2 (iPLA2) activity of Prdx6 .
|
-
- HY-151735
-
|
ADC Linker
|
Others
|
N3-L-Dab(Boc)-OH is a click chemistry reagent containing an azide group. N3-L-Dab(Boc)-OH can be used for the research of various biochemical .
|
-
- HY-W039756
-
NSC 334362
|
Amino Acid Derivatives
|
Others
|
Boc-Ala-Ala-OH (NSC 334362) is an Alanine derivative. Boc-Ala-Ala-OH is used in the preparation of anti-bacterial agent .
|
-
- HY-126488
-
-
- HY-W016424
-
-
- HY-P10231
-
|
Carboxypeptidase
|
Others
|
Ac-Phe-Thiaphe-OH is a modified peptide, which is utilized as substrate for carboxypeptidase A (CPA) .
|
-
- HY-W008555
-
-
- HY-121711
-
-
- HY-Y1636S1
-
|
Isotope-Labeled Compounds
|
Others
|
L-Arginine-N-FMOC PBF-OH- 13C6 is the 13C labeled Fmoc-Arg(Pbf)-OH[1]. Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis)[2].
|
-
- HY-151682
-
|
ADC Linker
|
Others
|
H-L-Lys(Norbornene-methoxycarbonyl)-OH, a norbornene-derivatized lysine, can be click-functionalized. H-L-Lys(Norbornene-methoxycarbonyl)-OH can be used for the mild and selective modification of proteins in a copper-free click reaction .
|
-
- HY-151682A
-
|
ADC Linker
|
Others
|
H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride, a norbornene-derivatized lysine, can be click-functionalized. H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride can be used for the mild and selective modification of proteins in a copper-free click reaction .
|
-
- HY-111975
-
7'-OH ABA
|
Others
|
Metabolic Disease
|
7'-Hydroxy ABA (7'-OH ABA) is a metabolite of Abscisic acid (Abscisic acid) through hydroxylation of the 7′-carbon atom of Abscisic acid. 7'-Hydroxy ABA exhibits significant hormonal activity .
|
-
- HY-141464
-
Fmoc-Asn(Ac3AcNH-beta-Glc)-OH
|
Amino Acid Derivatives
|
Cancer
|
Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH (Fmoc-Asn(Ac3AcNH-beta-Glc)-OH) can be used in the synthesis of silicon-fluoride acceptor (SiFA) derivatized octreotate derivatives. SiFA-octreotate analogues, as tumor imaging agents, are useful tool for the research of positron emission tomography (PET) .
|
-
- HY-W008452S
-
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
H-Tyr(3-I)-OH- 13C6 is the 13C-labeled H-Tyr(3-I)-OH. H-Tyr(3-I)-OH is a potent and effective tyrosine hydroxylase inhibitor. H-Tyr(3-I)-OH is an intermediate in the production of thyroid hormones and has a role as a human or mouse metabolite[1][2].
|
-
- HY-P4560
-
|
Angiotensin-converting Enzyme (ACE)
|
Cardiovascular Disease
|
H-Pro-Phe-OH is a dipeptide containing proline and phenylalanine, which can serve as a substrate for prolinase. H-Pro-Phe-OH can also be used for polypeptide synthesis, where phenylalanine is an aromatic amino acid that can inhibit the activity of Angiotensin-converting enzyme (ACE, HY-P2983) .
|
-
- HY-114782
-
L-Tyrosyl-L-tyrosine
|
Angiotensin-converting Enzyme (ACE)
|
Cardiovascular Disease
|
H-Tyr-Tyr-OH (L-Tyrosyl-L-tyrosine) is an antihypertensive peptide. H-Tyr-Tyr-OH inhibits angiotensin I-converting enzyme (ACE) with an IC50 value of 0.028 mg/mL. H-Tyr-Tyr-OH can be used for the research of high blood pressure .
|
-
- HY-126487
-
-
- HY-W008326
-
-
- HY-133803
-
-
- HY-W010986
-
-
- HY-131094
-
|
Others
|
Others
|
H-Gly-D-Tyr-OH is used for the the solid-phase peptide synthesis.
|
-
- HY-79131S3
-
-
- HY-W008999
-
-
- HY-W009023
-
-
- HY-W009403
-
-
- HY-W014919
-
-
- HY-W015177
-
-
- HY-W016031
-
-
- HY-W016555
-
-
- HY-W010825
-
-
- HY-W010894
-
-
- HY-W007615
-
-
- HY-W008269
-
-
- HY-W008486
-
-
- HY-W008527
-
-
- HY-W041866
-
-
- HY-W008995
-
-
- HY-W008971
-
-
- HY-W011154
-
-
- HY-W012487
-
-
- HY-W011178
-
-
- HY-W011021
-
-
- HY-W013714
-
-
- HY-W013874
-
-
- HY-W010931
-
-
- HY-W010871
-
-
- HY-W009402
-
-
- HY-W013735
-
-
- HY-151763
-
|
ADC Linker
|
Others
|
Boc-L-Aza-OH CHA is a click chemistry reagent containing an azide group.
|
-
- HY-Y1250S1
-
-
- HY-P5469
-
|
Formyl Peptide Receptor (FPR)
|
Others
|
WRW4-OH is a biological active peptide. (This peptide inhibits binding of one of formyl peptide receptor-like 1 (FPRL1) agonists WKYMVm to its specific receptor. FPRL1 is an important classical chemoattractant receptor that is expressed in phagocytic cells in the peripheral blood and brain. Activation of FPRL1 is closely related to inflammatory responses in the host defense mechanism and neurodegenerative disorders.)
|
-
- HY-W008315
-
-
- HY-W001954
-
-
- HY-W009204S1
-
-
- HY-W101495S3
-
-
- HY-79131S1
-
-
- HY-W008371S1
-
-
- HY-W009204S4
-
-
- HY-W010955
-
NSC 334018
|
Biochemical Assay Reagents
|
Others
|
Z-Phe-Leu-OH (NSC 334018) is a substrate for carboxypeptidase Y (CPY). Z-Phe-Leu-OH is incubated with recombinant CPY to determine peptidase activity .
|
-
- HY-W038702
-
|
ADC Linker
|
Cancer
|
Boc-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W023121
-
|
ADC Linker
|
Cancer
|
Fmoc-Gly-Gly-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-101153
-
|
ADC Linker
|
Cancer
|
MC-Val-Ala-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-147205B
-
-
- HY-P2614
-
|
Caspase
|
Others
|
Mca-DEVDAP-K(Dnp)-OH is a fluorogenic substrate for caspase-3 .
|
-
- HY-151668A
-
|
ADC Linker
|
Others
|
Z-L-Aha-OH (DCHA) is a click chemistry reagent containing azide group .
|
-
- HY-151683
-
|
ADC Linker
|
Others
|
H-L-Ser(Propargyl)-OH is a click chemistry reagent containing an alkyne group .
|
-
- HY-151683A
-
|
ADC Linker
|
Others
|
H-L-Ser(Propargyl)-OH hydrochloride is a click chemistry reagent containing an alkyne group .
|
-
- HY-140809
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG4-(CH2)3OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-(CH2)3OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-151718A
-
|
ADC Linker
|
Others
|
Boc-L-Tyr(PEG(3)-N3)-OH DCHA is a click chemistry reagent containing an azide group.
|
-
- HY-151715
-
|
ADC Linker
|
Others
|
N3-D-Dap(Fmoc)-OH is a click chemistry reagent. N3-D-Dap(Fmoc)-OH can be used as a component for coupling by click reaction and as an orthogonally protected diaminocarboxylic acid derivative .
|
-
- HY-151709A
-
|
ADC Linker
|
Others
|
N3-L-Cit-OH DCHA is a click chemistry reagent containing an azide group. N3-L-Cit-OH DCHA can be used to construct peptidomimetic ADC linkers using Click-chemistry .
|
-
- HY-140741
-
|
Liposome
PROTAC Linkers
|
Cancer
|
DSPE-PEG-OH, MW 2000 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Additionally, DSPE-PEG-OH, MW 2000 can also be used for drug delivery .
|
-
- HY-148326
-
|
ADC Linker
|
Others
|
Glu(OtBu)-Val-Cit-PAB-OH (compound L5-1c) is an non-cleavable ADC linker. Glu(OtBu)-Val-Cit-PAB-OH has been used to synthesis protein-tubulysin conjugates .
|
-
- HY-W007970
-
-
- HY-W008325
-
|
Biochemical Assay Reagents
|
Others
|
Boc-L-Dap-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W141810
-
H-Phe(4-NH2)-OH hydrochloride
|
Endogenous Metabolite
|
Others
|
4-Amino-L-phenylalanine (H-Phe(4-NH2)-OH) hydrochloride is an endogenous metabolite.
|
-
- HY-W022281
-
-
- HY-W011033
-
-
- HY-W008529
-
-
- HY-W013740
-
-
- HY-W013745
-
-
- HY-W013769
-
-
- HY-W013749
-
-
- HY-W010589
-
|
Endogenous Metabolite
|
Metabolic Disease
|
H-Abu-OH, one of the three isomers of aminobutyric acid, is elevated in the plasma of children with with Reye's syndrome, tyrosinemia, homocystinuria, nonketotic hyperglycinemia, and ornithine transcarbamylase deficiency.
|
-
- HY-Y1169S1
-
|
Isotope-Labeled Compounds
|
Others
|
Fmoc-Asp(OtBu)-OH- 13C4, 15N is the 13C and 15N labeled Fmoc-Asp(OtBu)-OH[1]. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis[2].
|
-
- HY-161191
-
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
Thalidomide-azetidine-piperazine-C2-O-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-azetidine-piperazine-C2-O-C2-OH can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-151689
-
|
ADC Linker
|
Others
|
(2S,3R)-Fmoc-Abu(3-N3)-OH is a click chemistry reagent containing an azide group. (2S,3R)-Fmoc-Abu(3-N3)-OH can be used for the research of various biochemical .
|
-
- HY-160543
-
|
ADC Cytotoxin
Topoisomerase
|
Cancer
|
Exatecan-amide-CH2-O-CH2-CH2-OH (Compound 4) is a derivative of Exatecan (HY-13631). Exatecan-amide-CH2-O-CH2-CH2-OH can be used for the research of cell proliferative diseases such as cancer .
|
-
- HY-W013152
-
-
- HY-W012907
-
-
- HY-W013779
-
-
- HY-W101495S1
-
-
- HY-W101495S2
-
-
- HY-W045822
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
Fmoc-Lys(Pal-Glu-OtBu)-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Lys(Pal-Glu-OtBu)-OH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-151678
-
|
ADC Linker
|
Others
|
N3-L-Lys(Mtt)-OH is a click chemistry reagent containing an azide group. N3-L-Lys(Mtt)-OH can introduce azide functions into the amino acid building block of peptide sequences at the N-terminal position.
|
-
- HY-130936
-
|
ADC Linker
|
Cancer
|
DBCO-Val-Cit-PABC-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Val-Cit-PABC-OH is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-151780
-
|
ADC Linker
|
Others
|
Fmoc-L-Dap(Pentynoyl)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Dap(Pentynoyl)-OH serves as an amino acid building block for introducing alkyne functions into peptide sequences by standard Fmoc/tBu protocols. The alkyne residue can be engaged for copper catalyzed click reaction with organic azides or with tetrazines for copper-free conjugations . Fmoc-L-Dap(Pentynoyl)-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-151496
-
|
Others
|
Others
|
H-Cys-Val-2-Nal-Met-OH is a peptide. H-Cys-Val-2-Nal-Met-OH is a peptidomimetic derivative that can be used to label short peptide sequences .
|
-
- HY-134458A
-
Lysyltyrosine TFA
|
P2X Receptor
|
Neurological Disease
|
H-Lys-Tyr-OH TFA (Lysyltyrosine TFA) is a dipeptide composed of lysine and tyrosine. H-Lys-Tyr-OH TFA prevents neurological diseases or improves brain function by promoting the release of noradrenaline and tyrosine into the brain .
|
-
- HY-102081
-
|
Others
|
Cancer
|
2OH-BNPP1 is an inhibitor of BUB1 kinase, a Ser/Thr kinase, used for the treatment of cancer.
|
-
- HY-78921
-
|
ADC Linker
|
Cancer
|
Fmoc-3VVD-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W048829
-
|
Amino Acid Derivatives
|
Others
|
Boc-Phe-Gly-OH is a Boc-protected phenylalanyl glycine derivative, can be used for the synthesis of agents or other compounds .
|
-
- HY-W009912
-
|
Amino Acid Derivatives
|
Others
|
H-Tyr(Me)-OH is a synthetic amino acid, and can enter into protein in E. coli in response to an amber nonsense codon .
|
-
- HY-W010499
-
|
Biochemical Assay Reagents
|
Others
|
H-D-Homoser-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W012908
-
|
Biochemical Assay Reagents
|
Others
|
H-DL-Pro-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W013081
-
|
Biochemical Assay Reagents
|
Others
|
Fmoc-Gln(Trt)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W010856
-
|
Biochemical Assay Reagents
|
Others
|
Fmoc-Orn(Boc)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W048700
-
-
- HY-P2661
-
-
- HY-151669
-
|
ADC Linker
|
Others
|
Fmoc-D-Aha-OH is a click chemistry reagent containing an azide . Fmoc-D-Aha-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-W009486
-
Tyrosylalanine
|
Others
|
Others
|
H-Tyr-Ala-OH (Tyrosylalanine) is a L-tyrosine- and L-alanine-containing dipeptide .
|
-
- HY-151658
-
|
ADC Linker
|
Others
|
H-L-Lys(N3-Gly)-OH is a click chemistry containing an azide group, a lysine derivative. H-L-Lys(N3-Gly)-OH can be incorporated into proteins for click modifications .
|
-
- HY-151658A
-
|
ADC Linker
|
Others
|
H-L-Lys(N3-Gly)-OH hydrochloride is a click chemistry containing an azide group, a lysine derivative. H-L-Lys(N3-Gly)-OH hydrochloride can be incorporated into proteins for click modifications .
|
-
- HY-19821S
-
-
- HY-W011982
-
-
- HY-130618
-
|
PROTAC Linkers
|
Cancer
|
Boc-C1-PEG3-C4-OH is a PROTAC linker, which refers to the Alkyl/ether composition. Boc-C1-PEG3-C4-OH can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins .
|
-
- HY-W010921S
-
-
- HY-W013750
-
-
- HY-W008997
-
-
- HY-W009284
-
-
- HY-W016018
-
-
- HY-W010758
-
-
- HY-W010957
-
-
- HY-W142008
-
-
- HY-W042001
-
-
- HY-W042006
-
-
- HY-W008996
-
-
- HY-W008972
-
-
- HY-W011472
-
-
- HY-W012485
-
-
- HY-W012486
-
-
- HY-W010974
-
-
- HY-W141945
-
-
- HY-W010946
-
-
- HY-W010927
-
-
- HY-W010926
-
-
- HY-79294
-
-
- HY-W017617
-
-
- HY-W016339
-
-
- HY-W016028
-
-
- HY-W015279
-
-
- HY-W042007
-
-
- HY-151639
-
|
ADC Linker
|
Others
|
(2S,4R)-H-L-Pro(4-N3)-OH is a click chemistry reagent containing an azide group. (2S,4R)-H-L-Pro(4-N3)-OH can be used for the research of various biochemical studies .
|
-
- HY-151639A
-
|
ADC Linker
|
Others
|
(2S,4R)-H-L-Pro(4-N3)-OH (hydrochloride) is a click chemistry reagent containing an azide group. (2S,4R)-H-L-Pro(4-N3)-OH (hydrochloride) can be used for the research of various biochemical studies .
|
-
- HY-W008235
-
-
- HY-W008558
-
-
- HY-126487A
-
-
- HY-140638
-
|
PROTAC Linkers
|
Cancer
|
Acrylate-PEG-OH (MW 3400) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140639
-
|
PROTAC Linkers
|
Cancer
|
Acrylate-PEG-OH (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140640
-
|
PROTAC Linkers
|
Cancer
|
Acrylate-PEG-OH (MW 10000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140642
-
|
PROTAC Linkers
|
Cancer
|
Aminooxy-PEG-OH (MW 2000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-79129
-
|
ADC Linker
|
Cancer
|
Fmoc-D-Trp(Boc)-OH is a cleavable ADC linker that used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-W013780S2
-
-
- HY-147205C
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG-OH (MW 5000) is a PEG-based PROTAC linker can be used in the synthesis of PROTAC .
|
-
- HY-147205D
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG-OH (MW 10000) is a PEG-based PROTAC linker can be used in the synthesis of PROTAC .
|
-
- HY-147205A
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG-OH (MW 2000) is a PEG-based PROTAC linker can be used in the synthesis of PROTAC .
|
-
- HY-147205
-
|
PROTAC Linkers
|
Others
|
Biotin-PEG-OH (MW 1000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W013726
-
-
- HY-147205E
-
|
Fluorescent Dye
|
Others
|
Biotin-PEG-OH (MW 20000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-103591
-
|
PSMA
|
Cancer
|
DUPA(OtBu)-OH is a DUPA precursor. DUPA is used as the targeting moiety to actively deliver Docetaxel (DTX) for treatment of Prostate-Specific Membrane Antigen (PSMA) expressing prostate cancer.
|
-
- HY-Y1169
-
4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate; Fmoc-L-Asp(OtBu)-OH
|
Amino Acid Derivatives
|
Others
|
Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .
|
-
- HY-P4192
-
|
ADC Linker
|
Cancer
|
Fomc-Gly-Gly-Phe-Gly-OH (compound D5) can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit .
|
-
- HY-131308
-
-
- HY-W042005
-
|
Amino Acid Derivatives
|
Others
|
H-D-Phe(3,4-DiCl)-OH is D-3,4-Dichlorophenylalanine, a amino acid derivative. H-D-Phe(3,4-DiCl)-OH shows protein synthesis activity .
|
-
- HY-W007941S
-
-
- HY-66007
-
-
- HY-W008308
-
-
- HY-W048674
-
Fmoc-O-acetyl-L-serine
|
Amino Acid Derivatives
|
Infection
|
Fmoc-Ser(Ac)-OH (Fmoc-O-acetyl-L-serine) is a Serine derivative. Fmoc-Ser(Ac)-OH can be used for the preparation of broad-spectrum coronavirus membrane fusion inhibitor .
|
-
- HY-141144
-
|
ADC Linker
|
Cancer
|
OPSS-Val-Cit-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130930
-
|
ADC Linker
|
Cancer
|
Acid-propionylamino-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-126353
-
|
ADC Linker
|
Cancer
|
Fmoc-Val-Ala-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130961
-
|
ADC Linker
|
Cancer
|
Boc-Val-Dil-Dap-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-131833
-
|
ADC Linker
|
Cancer
|
Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W540122
-
-
- HY-151684A
-
|
ADC Linker
|
Others
|
Boc-Ser(O-propargyl)-OH (DCHA) is a click chemistry reagent containing a propynyl group.
|
-
- HY-136440
-
Metronidazole-OH
|
Bacterial
Parasite
|
Infection
|
Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle .
|
-
- HY-W109513
-
|
Amino Acid Derivatives
|
Inflammation/Immunology
|
Boc-Lys(Z)-OH (DCHA) is a involves in synthesis thymosin β4, βg and β6 fragments, and increases E-rosette forming capacity in Lupus Nephritis model. Boc-Lys(Z)-OH (DCHA) involves in synthesis Boc-Lyz-OCH3 and acts as a reagent of peptidyl thrombin inhibitors production .
|
-
- HY-103596
-
Cereblon ligand 2; E3 ligase Ligand 2
|
E3 Ligase Ligand-Linker Conjugates
Autophagy
Apoptosis
|
Cancer
|
Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs .
|
-
- HY-I1111
-
-
- HY-W008034
-
|
Biochemical Assay Reagents
|
Others
|
Fmoc-L-Trp(Boc)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-151754
-
|
ADC Linker
|
Others
|
DACN(Tos2,6-OH) is a click chemistry reagent containing an Azide. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions. The reactivity of an alkyne heavily depends on the electronic and steric characteristics of the substituents as well as structural strain. In comparison to nonbent acyclic alkynes, cyclononyne alkynes show remarkably high reactivity. Such strain-promoted azide-alkyne cycloadditions (SPAAC) using cycloalkynes have served for reliable molecular conjugation in a broad range of fields. The nitrogens are used as connection points for a variety of functional units. In comparison to cyclooctynes, DACNs possess high thermal and chemical stability along with comparable click reactivity . DACN(Tos2,6-OH) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W012874
-
-
- HY-W011002
-
-
- HY-W022404
-
-
- HY-W010880
-
-
- HY-W016032
-
-
- HY-151664
-
|
ADC Linker
|
Others
|
H-alpha-Prg-D-Ala-OH is a click chemistry reagent containing an azide group .
|
-
- HY-W012479S
-
-
- HY-P2616
-
-
- HY-78921AG
-
|
ADC Linker
|
Cancer
|
Fmoc-3VVD-OH (GMP) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-P2396
-
-
- HY-P2400
-
-
- HY-P2405
-
-
- HY-P2390
-
-
- HY-P2393
-
-
- HY-P2398
-
-
- HY-P2409
-
-
- HY-P2410
-
-
- HY-P2386
-
-
- HY-P2385
-
-
- HY-130222
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
Mal-PEG2-Val-Cit-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-Val-Cit-PAB-OH also can be used as a PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-151734
-
|
ADC Linker
|
Others
|
(2R,3S)-Fmoc-Abu(3-N3)-OH is a click chemistry reagent containing an azide group .
|
-
- HY-151761
-
|
ADC Linker
|
Others
|
H-L-Lys(4-N3-Z)-OH hydrochloride is a click chemistry reagent containing an azide group. H-L-Lys(4-N3-Z)-OH hydrochloride contains a lysine-modified azide moiety and as a bioorthogonal ligation handle. H-L-Lys(4-N3-Z)-OH hydrochloride is an infrared probe and a photo-affinity reagent .
|
-
- HY-P4596S
-
-
- HY-157759
-
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
(S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-O-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-O-C2-OH can serve as a Cereblon ligand to recruit CRBN proteins and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-W009602
-
H-Phe-Ala-OH
|
Others
|
Others
|
Phenylalanylalanine (H-Phe-Ala-OH) is a dipeptide composed of phenylalanine and alanine. Phenylalanylalanine is an incomplete breakdown product of protein digestion or protein catabolism .
|
-
- HY-W052227
-
-
- HY-W008432
-
-
- HY-W010850
-
-
- HY-W013824
-
-
- HY-W011258
-
L-Tyrosyl-L-phenylalanine
|
Xanthine Oxidase
Angiotensin-converting Enzyme (ACE)
|
Inflammation/Immunology
Cancer
|
H-Tyr-Phe-OH (L-Tyrosyl-L-phenylalanine) is an orally active inhibitor of Angiotensin converting enzyme (ACE), with an inhibiton rate of 48% at 50 μM. H-Tyr-Phe-OH can be used as an biomarker for differentiating benign thyroid nodules (BTN) from thyroid cancer (TC). H-Tyr-Phe-OH exhibits xanthine oxidase inhibition (uric acid lowering) activity and serves as regulator in IL-8 production in neutrophil-like cells .
|
-
- HY-140732
-
(1,3-dioxoisoindolin-2-yl)-O-PEG-OH (MW 2000)
|
PROTAC Linkers
|
Cancer
|
Dioxoisoindolin-O-PEG-OH (MW 2000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W012479
-
-
- HY-W042008
-
-
- HY-W008205
-
Fmoc-L-Hydroxyproline
|
Biochemical Assay Reagents
|
Others
|
Fmoc-Hyp-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-151661
-
L-azidovaline (CHA)
|
ADC Linker
|
Others
|
N3-L-Val-OH (CHA) is a click chemistry containing an azide group, a valine derivative. N3-L-Val-OH (CHA) can also be used as a synthetic intermediate for Valaciclovir (Valacyclovir) .
|
-
- HY-P2402
-
-
- HY-151721
-
|
ADC Linker
|
Others
|
H-D-Orn(N3)-OH hydrochloride is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
-
- HY-151785A
-
|
ADC Linker
|
Others
|
H-L-Dbu(N3)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
-
- HY-151849
-
|
ADC Linker
|
Others
|
Z-L-Dap(N3)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
-
- HY-151858
-
|
ADC Linker
|
Others
|
Boc-L-Lys(N3)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
-
- HY-W048688
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Trp(Me)-OH is synthesized by N-(9-Fluorenylmethoxycarbonyloxy)succinimide (Fmoc-ONSu) and 1-Methyl-Ltrypthophan and can be used for protein or peptide synthesis .
|
-
- HY-114161
-
-
- HY-130820
-
|
PROTAC Linkers
|
Cancer
|
THP-PEG4-Pyrrolidine(N-Boc)-CH2OH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523) .
|
-
- HY-130821
-
|
PROTAC Linkers
|
Cancer
|
THP-PEG4-Pyrrolidine(N-Me)-CH2OH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523) .
|
-
- HY-109582
-
ADT-OH
1 Publications Verification
5-(4-Hydroxyphenyl)-3H-1,2-dithiole-3-thione; ACS 1
|
Apoptosis
|
Cancer
|
ADT-OH is a hydrogen sulfide-releasing donor. ADT-OH induces apoptosis and inhibits the development of melanoma in vivo by upregulating FADD. ADT-OH has the potential for the research of cancer diseases .
|
-
- HY-129774
-
|
PROTAC Linkers
|
Cancer
|
Phthalimide-PEG4-MPDM-OH is a PROTAC linker, which refers to the PEGs composition. Phthalimide-PEG4-MPDM-OH can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins .
|
-
- HY-130933
-
|
ADC Linker
|
Cancer
|
Fmoc-Ala-Ala-Asn(Trt)-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-151748
-
|
ADC Linker
|
Others
|
N3-L-Orn(Fmoc)-OH is a Fmoc-protected ornithine derivative, can be used as a click chemistry reagent.
|
-
- HY-P4596S1
-
-
- HY-151760A
-
|
ADC Linker
|
Others
|
(2R,4S)-H-D-Pro(4-N3)-OH hydrochloride is a click chemistry reagent containing an azide group.
|
-
- HY-151762
-
|
ADC Linker
|
Others
|
(2R,4S)-Fmoc-D-Pro(4-N3)-OH is a click chemistry reagent containing an azide group.
|
-
- HY-151848
-
|
ADC Linker
|
Others
|
(2R,4R)-Boc-D-Pro(4-N3)-OH is a click chemistry reagent containing an azide group.
|
-
- HY-N12513
-
-
- HY-W097167
-
-
- HY-130922
-
|
ADC Linker
|
Cancer
|
BCN-PEG1-Val-Cit-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG1-Val-Cit-OH is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-151786
-
|
ADC Linker
|
Others
|
Fmoc-L-Lys(Pentynoyl-DIM)-OH is a click chemistry reagent containing an azide. Fmoc-L-Lys(Pentynoyl-DIM)-OH can be used as a SPPS building block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution .
|
-
- HY-W014130A
-
-
- HY-42709
-
-
- HY-W012734
-
H-HoPro-OH
|
Endogenous Metabolite
|
Metabolic Disease
|
L-Pipecolic acid (H-HoPro-OH) is a breakdown product of lysine, accumulates in body fluids of infants with generalized genetic peroxisomal disorders, such as Zellweger syndrome, neonatal adrenoleukodystrophy.
|
-
- HY-151738
-
|
ADC Linker
|
Others
|
Fmoc-Aeg(N3)-OH is a click chemistry reagent containing an Azide. Alkylating the Nitrogen of an amide bond results in peptoid structures, which leads to conformational restrains, like N-methylation and allows backbone derivatisation. Altering cytotoxicity, bacterial cell selectivity and receptor pharmacology through formation of peptoid derivatives have been published for Cilengitide, Piscidin 1, and MC3, MC4 and MC5 receptor agonist. This building block enables design of macrocycles through intermolecular crosslinking or backbone stabilization through intermolecular ring-closure. This compound is a potential building block for the construction of (customized) peptide nucleic acids (PNAs) and for peptoid synthesis . Fmoc-Aeg(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-151674
-
|
ADC Linker
|
Others
|
N3-L-Cys(Trt)-OH (CHA) is a click chemistry reagent containing an azide group.
|
-
- HY-140580
-
|
PROTAC Linkers
|
Cancer
|
Bis(m-PEG4)-N-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W007743
-
Boc-L-pipecolic acid
|
Biochemical Assay Reagents
|
Others
|
Boc-Pip-OH (Boc-L-pipecolic acid) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-112061
-
8-Hydroxy-DPAT
|
5-HT Receptor
|
Neurological Disease
|
8-OH-DPAT is a potent and selective 5-HT agonist, with a pIC50 of 8.19 for 5-HT1A and a Ki of 466 nM for 5-HT7; 8-OH-DPAT weakly binds to 5-HT1B (pIC50, 5.42), 5-HT (pIC50 <5).
|
-
- HY-130934
-
|
ADC Linker
|
Cancer
|
TCO-PEG1-Val-Cit-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG1-Val-Cit-OH is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-P3971
-
|
TGF-beta/Smad
|
Inflammation/Immunology
|
H-Leu-Ser-Lys-Leu-OH (LSYL) is a latency-associated peptide at the amino terminus of LAP, with inhibitory effect on TGF-β1 activation. H-Leu-Ser-Lys-Leu-OH, binding with KRFK (HY-P3970), can block the signal transduction of TGF-β1, and prevent the progression of hepatic damage and fibrosis .
|
-
- HY-W014423
-
-
- HY-151836
-
|
ADC Linker
|
Others
|
(2S,3R)-H-Abu(3-N3)-OH (hydrochloride) is a click chemistry reagent containing an azide group . (2S,3R)-H-Abu(3-N3)-OH (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-151838
-
|
ADC Linker
|
Others
|
(2S,3S)-H-Abu(3-N3)-OH (hydrochloride) is a click chemistry reagent containing an azide group . (2S,3S)-H-Abu(3-N3)-OH (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-P2389
-
-
- HY-P2395
-
-
- HY-P2397
-
-
- HY-P2399
-
-
- HY-P2401
-
-
- HY-P2403
-
-
- HY-P2404
-
-
- HY-P2407
-
-
- HY-P2408
-
-
- HY-P2384
-
-
- HY-P2388
-
-
- HY-P2411
-
-
- HY-P2391
-
-
- HY-P2412
-
-
- HY-P2387
-
-
- HY-161188
-
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
Thalidomide-O-C4H4-N(Me)-piperidine-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-O-C4H4-N(Me)-piperidine-C2-OH can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-161190
-
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
Thalidomide-piperidine-C-2,6-diazaspiro[3.3]heptane-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-piperidine-C-2,6-diazaspiro[3.3]heptane-C2-OH can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-W022255
-
D-Fmoc-glutamic acid
|
Amino Acid Derivatives
|
Others
|
Fmoc-D-Glu-OH (D-Fmoc-glutamic acid) is a derivative of glutamate, can be used to prepare supramolecular hydrogels .
|
-
- HY-151731
-
|
ADC Linker
|
Others
|
N3-1,4-trans-CHC-OH is a click chemistry reagent containing an azide group.
|
-
- HY-W009673
-
N-Boc-L-pyroglutamic acid
|
Biochemical Assay Reagents
|
Others
|
Boc-Pyr-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-P2616A
-
-
- HY-139276
-
|
GLP Receptor
|
Others
|
Pal-Glu(OSu)-OH is a side chain of Liraglutide. Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used for type 2 diabetes mellitus research .
|
-
- HY-151653
-
O-Propargyl-D-tyrosine
|
ADC Linker
|
Others
|
H-D-Tyr(Propargyl)-OH is a click chemistry reagent containing an Azide . H-D-Tyr(Propargyl)-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-151782A
-
|
ADC Linker
|
Others
|
H-(Gly)3-Lys(N3)-OH (hydrochloride) is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
-
- HY-114424
-
-
- HY-114424A
-
-
- HY-W102456
-
L-4-Acetylphenylalanine
|
Others
|
Others
|
H-Phe(4-Ac)-OH is a keto-containing amino acid, which can be conversed from α-keto acids containing acetyl. H-Phe(4-Ac)-OH can be incorporated at the amber position to afford the mutant Z domain protein .
|
-
- HY-150013
-
L-Methionyl-L-methionine
|
Others
|
Others
|
H-Met-Met-OH (L-Methionyl-L-methionine) is a dipeptide composed of two methionine residues .
|
-
- HY-113089A
-
H-Glu(H-Lys-OH)-OH TFA; γ-Glu-ε-Lys TFA
|
Endogenous Metabolite
|
Metabolic Disease
|
Epsilon-(gamma-glutamyl)-lysine (H-Glu(H-Lys-OH)-OH) TFA is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration .
|
-
- HY-P2608
-
|
Fluorescent Dye
|
Others
|
DNP-Pro-Leu-Ala-Leu-Trp-Ala-Arg-OH is the substrate for matrix metalloproteinase MMP-1, with a Km of 26.61 μM. DNP-Pro-Leu-Ala-Leu-Trp-Ala-Arg-OH is utilized as fluorescence probe for detecting protein activity .
|
-
- HY-W010591
-
-
- HY-P2394
-
-
- HY-15688
-
8-Hydroxy-DPAT hydrobromide
|
5-HT Receptor
|
Neurological Disease
|
8-OH-DPAT (8-Hydroxy-DPAT) hydrobromide is a potent and selective 5-HT1A agonist with a pIC50 of 8.19. 8-OH-DPAT hydrobromide has selectivity of almost 1000 fold for a subtype of the 5-HT1 binding site .
|
-
- HY-130956
-
|
ADC Linker
|
Cancer
|
Boc-NMe-Val-Val-Dil-Dap-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-W013473
-
Boc-D-Pipecolic acid
|
Biochemical Assay Reagents
|
Others
|
Boc-D-HoPro-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-42912
-
|
Others
|
Cancer
|
N-Boc-dolaproine-OH ((+)-phenylethylamine) is the amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity .
|
-
- HY-42912A
-
|
Others
|
Cancer
|
N-Boc-dolaproine-OH dicyclohexylamine is the amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity .
|
-
- HY-151687
-
|
ADC Linker
|
Others
|
Fmoc-L-Tyr(2-azidoethyl)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Tyr(2-azidoethyl)-OH is unnatural Fmoc-protected Tyrosine derivative bears an azidoethyl substitution as reactive handle e.g. for biorthogonal conjugations, via a Cu(I)-catalyzed 1,3-dipolar Click cycloaddition with alkynes. And azido-UAAs can be employed as IR reporters .
|
-
- HY-151703A
-
|
ADC Linker
|
Others
|
Boc-D-Lys(N3)-OH CHA is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
-
- HY-W007798S
-
-
- HY-P2718
-
-
- HY-151677
-
|
ADC Linker
|
Others
|
(2R,4S)-Boc-D-Pro(4-N3)-OH is a click chemistry reagent containing an azide . (2R,4S)-Boc-D-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-151850
-
|
ADC Linker
|
Others
|
(2S,4R)-Fmoc-L-Pro(4-N3)-OH is a click chemistry reagent containing an azide . (2S,4R)-Fmoc-L-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-114161A
-
-
- HY-P1449
-
|
ADC Linker
|
Cancer
|
Boc-Gly-Gly-Phe-Gly-OH, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).
|
-
- HY-W012908S
-
-
- HY-N9446
-
|
Endogenous Metabolite
|
Others
|
H-Asn(glcnac-beta-D)-OH is an endogenous metabolite present in Urine that can be used for the research of NGLY1-CDDG .
|
-
- HY-151826
-
|
ADC Linker
|
Others
|
Fmoc-D-Lys(pentynoyl)-OH is a click chemistry reagent containing an azide group. Used to introduce alkyne functionality into peptides that can be further modified using Click-chemistry .
|
-
- HY-151654
-
|
ADC Linker
|
Others
|
N3-D-Lys(Boc)-OH is a click chemistry reagent containing an Azide . N3-D-Lys(Boc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-151729
-
|
ADC Linker
|
Others
|
N3-D-Dab(Boc)-OH is a click chemistry reagent containing an Azide . N3-D-Dab(Boc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-151841
-
|
ADC Linker
|
Others
|
N3-L-Lys(Boc)-OH is a click chemistry reagent containing an azide group . N3-L-Lys(Boc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-151843
-
|
ADC Linker
|
Others
|
N3-L-Lys(Fmoc)-OH is a click chemistry reagent containing an azide group . N3-L-Lys(Fmoc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-130923
-
|
ADC Linker
|
Cancer
|
BCN-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG1-Val-Cit-PABC-OH is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-U00050
-
E-10-OH-NT
|
Drug Metabolite
|
Neurological Disease
|
(E)-10-Hydroxynortriptyline (E-10-OH-NT) is a metabolite of Nortriptyline (HY-B1417). Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline (HY-B0527A) . E-10-OH-NT is about 50% as potent as nortriptyline as an inhibitor of the neuronal uptake of norepinephrine in vitro and exhibits less anticholinergic effects in man.
|
-
- HY-P2392
-
-
- HY-P3786
-
|
PKA
PKC
|
Cancer
|
H-Arg-Gly-Tyr-Ala-Leu-Gly-OH is a competitive and CAMP dependent protein kinase inhibitor .
|
-
- HY-W008753
-
N-Cbz-L-valine
|
Biochemical Assay Reagents
|
Others
|
Z-L-Val-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-133459
-
|
ADC Linker
|
Cancer
|
Mal-PEG1-Val-Cit-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-P1853
-
-
- HY-140149
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
Azido-PEG4-Val-Cit-PAB-OH is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG4-Val-Cit-PAB-OH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-Val-Cit-PAB-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-W014130
-
Ac-Arg-OH
|
Endogenous Metabolite
|
Others
|
N-Acetyl-L-arginine (Ac-Arg-OH) is one of the guanidino compounds found elevated in the serum of an hemodialyzed renal insufficient (uremic) pediatric population.
|
-
- HY-I1111S1
-
-
- HY-151760
-
|
ADC Linker
|
Others
|
(2R,4S)-H-D-Pro(4-N3)-OH is a click chemistry reagent containing an azide group . (2R,4S)-H-D-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-151839
-
|
ADC Linker
|
Others
|
(2R,4R)-H-D-Pro(4-N3)-OH (hydrochloride) is a click chemistry reagent containing an azide group . (2R,4R)-H-D-Pro(4-N3)-OH (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-107378
-
-
- HY-130966
-
|
ADC Linker
|
Cancer
|
TCO-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG1-Val-Cit-PABC-OH is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-147104
-
|
Fluorescent Dye
|
Others
|
Fmoc-Lys(5-FITC)-OH is a marker for polypeptides or proteins. FITC is a fluorescence probe for the labeling of amines. FITC is a pH- and Cu 2+-sensitive fluorescence dye .
|
-
- HY-151777
-
|
ADC Linker
|
Others
|
N3-Gly-Gly-Gly-Gly-Gly-OH is a click chemistry reagent containing an azide group.
|
-
- HY-W008689
-
N-Fmoc-6-AminOHexanoic acid
|
Biochemical Assay Reagents
|
Others
|
Fmoc-ε-Acp-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W016781
-
H-D-Arg-OH
|
Endogenous Metabolite
|
Others
|
D-arginine (H-D-Arg-OH) is the D-isomer of arginine. Arginine is an α-amino acid that is used in the biosynthesis of proteins. D-Arginine is an inactive form of L-arginine .
|
-
- HY-P2536
-
-
- HY-136034
-
|
ADC Linker
|
Cancer
|
Azido-PEG1-Val-Cit-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG1-Val-Cit-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-75332
-
D-Cbz phenylglycine
|
Amino Acid Derivatives
|
Others
|
Z-D-Phg-OH (D-Cbz phenylglycine) is a N-blocked amino acids with Kd values of 390 μM and 323 μM for tBuCQN and tBuCQD, respectively .
|
-
- HY-151677A
-
|
ADC Linker
|
Others
|
(2R,4S)-Boc-D-Pro(4-N3)-OH DCHA is a click chemistry reagent containing an azide . (2R,4S)-Boc-D-Pro(4-N3)-OH (DCHA) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-151828
-
|
ADC Linker
|
Others
|
N3-Gly-Aeg(Fmoc)-OH is a click chemistry reagent containing an azide group. PNA building-block that can be further modified using Click-chemistry .
|
-
- HY-15400
-
-
- HY-P1449A
-
|
ADC Linker
|
Cancer
|
Boc-Gly-Gly-Phe-Gly-OH TFA, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).
|
-
- HY-19821S1
-
Fmoc-L-isoleucine-13C6,15N
|
Isotope-Labeled Compounds
|
Others
|
Fmoc-Ile-OH- 13C6, 15N is the 13C and 15N labeled Fmoc-Ile-OH[1]. Fmoc-Ile-OH is an isoleucine derivative[2].
|
-
- HY-P4549
-
-
- HY-111121
-
Mal-cyclobutane-1,1-dicarboxamide-Cit-PAB
|
ADC Linker
|
Cancer
|
cBu-Cit-OH (Mal-cyclobutane-1) is an ADC Linker that can be used to synthesize ADCs .
|
-
- HY-140143
-
|
ADC Linker
|
Cancer
|
Mal-PEG4-Val-Cit-PAB-OH is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130944
-
|
ADC Linker
|
Cancer
|
Mal-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-151781
-
|
ADC Linker
|
Others
|
Fmoc-L-Dap(Poc)-OH is a click chemistry reagent containing an azide group. Amino acid building block suitable for side chain Click conjugation with standard protocols and together with tetrazine linkers in copper-free Click conjugation (Diels-Alder) .
|
-
- HY-W005720
-
-
- HY-132988
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Tyr(3-F,tBu)-OH is a cyclic peptide compound with high membrane permeability and can specifically binds to a target molecule (extracted from patent WO2018225864A1) .
|
-
- HY-41121S1
-
-
- HY-P4561
-
|
Cathepsin
|
Others
|
H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH is a water-soluble polypeptide that can serve as a substrate for cathepsin D, pepsin and pepsinogen. H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH has potential applications in biochemical analysis .
|
-
- HY-151764
-
|
ADC Linker
|
Others
|
N3-D-Orn(Boc)-OH is a Boc-protected pentanoic amino acid derivative, can be used as a click chemistry reagent and has been used to synthesis antibody-drug conjugates (ADC) .
|
-
- HY-151829
-
|
ADC Linker
|
Others
|
Fmoc-L-Asn(EDA-N3)-OH is a click chemistry reagent containing an azide group. This building block is reported in literature for the modification of Amanitin via Click Chemistry. Alpha-Amanitin is the deadliest member of the amatoxin peptide family produced by the death-cap mushroom A. phalloides. It is an orally available, rigid, bicyclic octapeptide and one of the most lethal known natural products (LD50 = 50-100 μg/kg) acting as highly selective allosteric inhibitor of the RNA polymerase II .
|
-
- HY-151736
-
|
ADC Linker
|
Others
|
N3-L-Dap(Boc)-OH is a click chemistry reagent containing an azide group. Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompatible, rapid and highly specific in biological environments . N3-L-Dap(Boc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-151749
-
|
ADC Linker
|
Others
|
N3-D-Lys(Fmoc)-OH is a click chemistry reagent containing an azide group. Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompatible, rapid and highly specific in biological environments . N3-D-Lys(Fmoc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-W010104
-
H-Met(O)-OH
|
Endogenous Metabolite
|
Metabolic Disease
|
L-Methionine sulfoxide (H-Met(O)-OH), a metabolite of Methionine, induces M1/classical macrophage polarization, and modulates oxidative stress and purinergic signaling parameters .
|
-
- HY-113003
-
γ-Glutamylglutamine; γ-Glu-Gln
|
Others
|
Others
|
H-γ-Glu-Gln-OH is a hydrophilic peptide and can be conjugated to drugs. The carrier composed of H-γ-Glu-Gln-OH has the characteristics of high water solubility and drug-loading capacity, good biocompatibility, low toxicity, improved tumor targeting ability, and anti-tumor efficacy .
|
-
- HY-41912B
-
Boc-D-Nle-OH; N-BOC-D-norleucine
|
Amino Acid Derivatives
|
Others
|
Boc-D-norleucine (Boc-D-Nle-OH) is a leucine derivative that can be used for peptide synthesis .
|
-
- HY-151659
-
|
ADC Linker
|
Others
|
Fmoc-L-Lys(N3-Gly)-OH is a click chemistry reagent containing a lysine-containing azidoacetyl group building-block for SPPS and can be used for various biochemical studies .
|
-
- HY-W013780S
-
|
Isotope-Labeled Compounds
Autophagy
Bacterial
Antibiotic
|
Infection
|
Fmoc-Pro-OH-1- 13C is a 13C-labeled Sulfabenzamide. Sulfabenzamide (N-Sulfanilylbenzamide) is an antimicrobial agent and usually consumed in combination with Sulfathiazole and Sulfacetamide. Sulfabenzamide is effective against Gram-positive and negative ba
|
-
- HY-161197
-
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
Thalidomide-2,6-diazaspiro[3.4]octane-C-piperidine-C2-O-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-2,6-diazaspiro[3.4]octane-C-piperidine-C2-O-C2-OH can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-140148
-
|
ADC Linker
|
Cancer
|
Azido-PEG3-Val-Cit-PAB-OH is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG3-Val-Cit-PAB-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-136137
-
|
ADC Linker
|
Cancer
|
Azide-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azide-PEG1-Val-Cit-PABC-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-151784
-
|
ADC Linker
|
Others
|
Boc-D-Aza-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
-
- HY-140569
-
|
PROTAC Linkers
|
Cancer
|
N-(PEG1-OH)-N-Boc-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(PEG1-OH)-N-Boc-PEG2-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-151930
-
8'-OH-ABA
|
Drug Metabolite
|
Metabolic Disease
|
8′-Hydroxy ABA (8'-OH-ABA) is a principal catabolite of abscisic acid (ABA). 8′-Hydroxy ABA has hormonal activity and leads to increased oil synthesis. 8′-Hydroxy ABA is a labile compound .
|
-
- HY-141146
-
|
ADC Linker
|
Cancer
|
Mal-amido-PEG8-val-gly-PAB-OH is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140146
-
|
ADC Linker
|
Cancer
|
Mal-amido-PEG2-Val-Cit-PAB-OH is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-151679
-
|
ADC Linker
|
Others
|
Fmoc-L-Lys(4-N3-Z)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Lys(4-N3-Z)-OH acts as Lysine building-block for SPPS containing an Azide moiety as a bioorthogonal ligation handle, an infrared probe and a photo-affinity reagent. It can be decaged by trans-cyclooctenols via a strain-promoted 1,3-dipolar cycloaddition . Fmoc-L-Lys(4-N3-Z)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-W008642S
-
L-Leucyl-13C6,15N-L-leucine
|
Isotope-Labeled Compounds
|
Others
|
(Leu-13C6,15N)-Leu-OH TFA is a C13 and N15 labeled Leu-Leu-OH TFA. Leu-Leu-OH, a Leu derivative, is a dipeptide .
|
-
- HY-I1111S4
-
|
Isotope-Labeled Compounds
|
Others
|
Fmoc-L-Val-OH- 15N is a 15N-labeled Leucomalachite green. Leucomalachite green is a triphenylmethane dye used to detect blood. Leucomalachite green, a major metabolite of malachite green, is a potential carcinogen, teratogen and mutagen[1][2].
|
-
- HY-151845
-
|
ADC Linker
|
Others
|
N3-PhAc-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
-
- HY-W012000
-
Boc-N-Me-Ile-OH
|
Amino Acid Derivatives
|
Others
|
Boc-N-methyl-L-isoleucine (Boc-N-Me-Ile-OH) is a peptide products and can be used as a precursor in organic synthesis and pharmaceuticals .
|
-
- HY-W048487
-
N6-Benzoyl-7'-OH-Morpholino adenosine
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
N6-Benzoyl-7’-OH-morpholino adenine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-140997
-
|
PROTAC Linkers
|
Cancer
|
Mal-PEG4-Glu(OH)-NH-m-PEG24 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W012159
-
H-MET-SER-OH
|
Angiotensin-converting Enzyme (ACE)
|
Cardiovascular Disease
|
Methionylserine (H-MET-SER-OH) is a methionine- and serine-containing dipeptide. Methionylserine binds to and translocation via intestinal di/tri-peptide transporter 1 (hPEPT1) with a Km value of 0.2 mM. Methionylserine inhibits ACE enzyme activity. Methionylserine can be used in the research of hypension .
|
-
- HY-W010378
-
H-D-Asn-OH
|
Endogenous Metabolite
|
Metabolic Disease
|
D-Asparagine (H-D-Asn-OH) is a competitive inhibitor of L-Asparagine hydrolysis with a Ki value of 0.24 mM. D-Asparagine is a source of nitrogen for yeast strains. D-Asparagine is a good substrate for the external yeast asparaginase but is a poor substrate for the internal enzyme .
|
-
- HY-W111141
-
endo-9-Hydroxymethylbicyclo[6.1.0]non-4-yne
|
Biochemical Assay Reagents
|
Others
|
BCN-OH (endo-9-Hydroxymethylbicyclo[6.1.0]non-4-yne) is a mitochondrial probe based on the lyophilic bidentate bicyclic ligand BCN and is a control reagent for BCN-TPP. The TPP group is a reactive sulfenic acid probe that targets mitochondria. BCN-TPP is known to affect mitochondrial energy, causing a sharp decrease in basal respiration, causing it to exhibit faster reaction kinetics with sulfonated proteins. BCN-OH does not contain hydrophobic triphenylphosphonium (TPP) ions. Using BCN-OH as a control allows the TPP group to be safely introduced when designing sulfenic acid traps .
|
-
- HY-151764A
-
|
ADC Linker
|
Others
|
N3-D-Orn(Boc)-OH (CHA) is a Boc-protected pentanoic amino acid derivative, can be used as a click chemistry reagent and has been used to synthesis antibody-drug conjugates (ADC) .
|
-
- HY-22062
-
-
- HY-P0073
-
Met-Enkephalin; Methionine enkephalin; Metenkefalin
|
Opioid Receptor
|
Neurological Disease
Cancer
|
Tyr-Gly-Gly-Phe-Met-OH regulates human immune function and inhibits tumor growth via binding to the opioid receptor.
|
-
- HY-76317
-
N-Cbz-DL-proline; DL-Cbz-Proline
|
Amino Acid Derivatives
|
Others
|
Z-DL-Pro-OH (N-Cbz-DL-proline) is a proline derivative, can be used for the synthesis of agents or other compounds .
|
-
- HY-W007706S
-
-
- HY-W145646
-
|
Biochemical Assay Reagents
|
Others
|
Fmoc-L-Ser((Ac)4-β-D-Glc)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-Y1250S4
-
|
Fungal
|
Infection
Cancer
|
Fmoc-Gly-OH-1- 13C is a 13C-labeled Carbendazim. Carbendazim is a potent and orally active broad-spectrum benzimidazole fungicide and can be acts as a pesticide for fungal diseases research, such as Seproria, Fusarium and Sclerotina[1][3]. Carbendazim is a
|
-
- HY-41912
-
N-[(1,1-Dimethylethoxy)carbonyl]-L-norleucine; BOC-L-norleucine; BOC-norleucine; N-(tert-Butoxycarbonyl)norleucine
|
Amino Acid Derivatives
|
Others
|
Boc-Nle-OH is a leucine derivative .
|
-
- HY-W419403
-
|
ADC Linker
|
Others
|
Boc-D-Aza-OH (CHA) is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
-
- HY-151814
-
|
ADC Linker
|
Others
|
(2S,4S)-Fmoc-L-Pro(4-NHPoc)-OH is a click chemistry reagent containing an azide group.
|
-
- HY-W101495S
-
-
- HY-W052227S
-
-
- HY-16658B
-
Z-VAD-FMK
Maximum Cited Publications
309 Publications Verification
Z-VAD(OH)-FMK
|
Caspase
Apoptosis
|
Cancer
|
Z-VAD-FMK (Z-VAD(OH)-FMK) is a well-know pan caspase inhibitor, which does not inhibit ubiquitin carboxy-terminal hydrolase L1 (UCHL1) activity even at concentrations as high as 440 μM .
|
-
- HY-151846
-
|
ADC Linker
|
Others
|
Boc-L-Pra-OH (DCHA) is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
-
- HY-151859
-
|
ADC Linker
|
Others
|
N3-Gly-Gly-OH is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
-
- HY-145245
-
-
- HY-151865A
-
|
ADC Linker
|
Others
|
(2S,4S)-H-L-Pro(4-N3)-OH (hydrochloride) is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
-
- HY-W101718
-
|
Isotope-Labeled Compounds
ADC Linker
|
Cancer
|
Fmoc-N-(2-Boc-aminoethyl)-Gly-OH is a Fmoc-protected glycine derivative that can be used in antibody agent coupling (ADC) synthesis. ADC consists of antibodies that are linked to ADC cytotoxins via ADC junctions[1].
|
-
- HY-79128S1
-
-
- HY-131087
-
|
ADC Linker
|
Cancer
|
Me-triacetyl-β-D-glucopyranuronate-Ph-CH2OH-Fmoc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-151825
-
|
ADC Linker
|
Others
|
Fmoc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent containing an azide group. Used as an orthogonally protected building block in solid-phase peptide synthesis. Poc-group can be further modified using Click-chemistry .
|
-
- HY-151746
-
|
ADC Linker
|
Others
|
N3-Gly-Gly-Gly-OH is a oligo-Gly click chemistry reagent containing an azide group. Oligo-Gly also has been used as linker to combine different subunits of dimeric or oligomeric proteins or to create artificial multi-domain proteins. By modification into Gly-Gly-Gly-Ser motifs high solubility can be achieved . N3-Gly-Gly-Gly-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-151865
-
|
ADC Linker
|
Others
|
(2S,4S)-H-L-Pro(4-N3)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
-
- HY-W009204S5
-
|
Isotope-Labeled Compounds
PPAR
|
Metabolic Disease
|
Fmoc-Ala-OH- 13C3 is a 13C-labeled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-ind
|
-
- HY-151861
-
|
ADC Linker
|
Others
|
N3-Aca-Aca-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
-
- HY-W014423S4
-
-
- HY-113482
-
1β-OH-DCA
|
Endogenous Metabolite
Cytochrome P450
|
Metabolic Disease
|
1β-Hydroxydeoxycholic acid (1β-OH-DCA), a secondary bile acid, is a CYP3A biomarker. Deoxycholic acid is specifically metabolized into 1β-Hydroxydeoxycholic acid by CYP3A4 and CYP3A7 using recombinant human CYP450 enzymes .
|
-
- HY-P1200
-
|
Src
|
Cancer
|
Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH (compound 1) is a high-affinity pentapeptide to bind to the src SH2 domain (IC50≈1 µM). Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH is an inhibitor for src SH3-SH2:phosphoprotein interactions .
|
-
- HY-140241
-
|
PROTAC Linkers
|
Cancer
|
NH2-PEG4-Glu(OH)-NH-m-PEG24 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140697
-
mPEG-Hydroxy (MW5000); Polyethylene glycol monomethyl ether (MW5000)
|
PROTAC Linkers
|
Cancer
|
m-PEG-OH (MW5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140696
-
mPEG-Hydroxy (MW 2000); Polyethylene glycol monomethyl ether (MW 2000)
|
PROTAC Linkers
|
Cancer
|
m-PEG-OH (MW 2000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
- HY-151650
-
|
ADC Linker
|
Others
|
N3-O2Oc-O2Oc-OH is a click chemistry reagent containing an azide . N3-O2Oc-O2Oc-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-P10038
-
Myr-FEEERA-OH
|
Integrin
|
Infection
|
mP6 (Myr-FEEERA-OH) is a myristoylated peptide. mP6 inhibits the interaction of Gα13 with integrin β3 without disrupting talin-dependent integrin function. mP6 can block the GTP usage of Rac1, Rap1, and Rab7, effectively inhibiting the infection of CHO-A24 cells .
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-
- HY-151853A
-
|
ADC Linker
|
Others
|
N3-L-Leu-OH (BHA) is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
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-
- HY-W014423S
-
H-His-OH-13C hydrochloride hydrate
|
Endogenous Metabolite
|
Metabolic Disease
|
L-Histidine- 13C (hydrochloride hydrate) is the 13C-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
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-
- HY-W014423S6
-
-
- HY-153195
-
|
Others
|
Cancer
|
Tetra-O-acetyl-β-D-galactopyranosyl-Ph-CH2OH-Fmoc can be used as conjugates to prepare antibody drug conjugates (ADCs) .
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-
- HY-151681
-
cis-4-Azido-N-Fmoc-D-proline
|
ADC Linker
|
Others
|
(2R,4R)-Fmoc-D-Pro(4-N3)-OH (cis-4-Azido-N-Fmoc-D-proline) is a click chemistry reagent containing an azide group .
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-
- HY-W002299
-
Boc-D-Leu-OH hydrate
|
Amino Acid Derivatives
|
Neurological Disease
|
Boc-D-Leucine monohydrate (Boc-D-Leu-OH hydrate) is an N-Boc-protected form of D-Leucine (L330150). D-Leucine is an unnatural isomer of L-Leucine (L330110) that acts as an auto-inhibitor of lactic streptococci. D-Leucine shows potent anti-seizure effect .
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-
- HY-W014423S7
-
-
- HY-151766
-
|
ADC Linker
|
Others
|
DACN(Tos,Suc-OH) is a click chemistry reagent containing a cycloalkyne group. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions. Such strain-promoted azide-alkyne cycloadditions (SPAAC) using cycloalkynes have served for reliable molecular conjugation in a broad range of fields. The nitrogens are used as connection points for a variety of functional units. DACNs possess high thermal and chemical stability along with comparable click reactivity .
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-
- HY-151859A
-
|
ADC Linker
|
Others
|
N3-Gly-Gly-OH (DCHA) is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
-
- HY-W008016S
-
-
- HY-W011092
-
Nα-Boc-Nδ-Cbz-L-ornithine
|
Others
|
Inflammation/Immunology
|
Boc-Orn(Z)-OH (Nα-Boc-Nδ-Cbz-L-ornithine) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-118294
-
16-Phenoxy tetranor prostaglandin F2α isopropyl ester; 16-Phenoxy tetranor PGF2α isopropyl ester
|
Others
|
Cardiovascular Disease
|
15-OH Tafluprost, a prostaglandin F2a (PGF2a) analog, relieves endothelin-1 (ET-1)-induced optic nerve head (ONH) blood flow impairment and ET-1-induced contraction of isolated ciliary artery segments .
|
-
- HY-W357202
-
PMO Thymidine Precusor
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
7’-OH-N-trityl morpholinothymine (PMO Thymidine Precusor) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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-
- HY-W012874S
-
-
- HY-151779
-
|
ADC Linker
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Others
|
N3-L-Dab(Fmoc)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
-
- HY-136440S
-
Metronidazole-OH-d4
|
Isotope-Labeled Compounds
Bacterial
Parasite
|
Infection
|
Hydroxymetronidazole-d4 is the deuterium labeled Hydroxymetronidazole. Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle[1].
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-
- HY-W013780S1
-
|
Isotope-Labeled Compounds
Fungal
|
Infection
|
Fmoc-Pro-OH- 13C5, 15N is a 15N-labeled and 13C-labled Pyrimethanil. Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops[1]. Pyrimethanil inhibits the biosynthesis of methioni
|
-
- HY-P1200A
-
|
Src
|
Cancer
|
Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA (compound 1) is a high-affinity pentapeptide to bind to the src SH2 domain (IC50≈1 µM). Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA is an inhibitor for src SH3-SH2:phosphoprotein interactions .
|
-
- HY-137397
-
8-OH-EFV
|
Apoptosis
JNK
|
Cancer
|
8-Hydroxyefavirenz (8-OH-EFV) is a primary metabolite of (HY-10572). 8-Hydroxyefavirenz induces apoptosis via a JNK- and BimEL-dependent mechanism in primary human hepatocytes. 8-Hydroxyefavirenz can be used in research of cancer . 8-Hydroxyefavirenz is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-105858
-
H-Ile-Trp-OH; IW-2143
|
nAChR
|
Neurological Disease
|
BNC210 (H-Ile-Trp-OH) is an orally active α7 nAChR negative alteration modulator (NAM) with no apparent side effects. BNC210 exhibits acute anxiolytic activity in rodent models of anxiety. BNC210 can be used in studies of generalised anxiety disorders .
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-
- HY-151676
-
N-Boc-O-(2-azidoethyl)-L-tyrosine
|
ADC Linker
|
Others
|
Boc-L-Tyr(2-azidoethyl)-OH (N-Boc-O-(2-azidoethyl)-L-tyrosine) is a click chemistry reagent containing an azide group .
|
-
- HY-W015236
-
Triglycine
|
Biochemical Assay Reagents
|
Others
|
H-Gly-Gly-Gly-OH, also known as Triglycine, is a tripeptide composed of glycine, glycine and glycine, which are linked by peptide bonds. Often used as a model compound in the study of protein structure and function. Glycylglycylglycine also acts as a neurotransmitter in the central nervous system and has been shown to have antioxidant properties. Furthermore, it may have potential research roles in various diseases such as cancer, diabetes and neurodegenerative diseases.
|
-
- HY-I1111S2
-
-
- HY-W101298S
-
L-Leucyl-13C6,15N-L-isoleucine TFA
|
Isotope-Labeled Compounds
|
Neurological Disease
|
(Leu-13C6,15N)-Ile-OH (L-Leucyl-13C6,15N-L-isoleucine) TFA is the deuterium labeled Leu-Ile-OH. Leu-Ile-OH protects against neuronal death by inducing brain-derived neurotrophic factor (BDNF) and glial cell line-derived neurotrophic factor (GDNF) synthesis .
|
-
- HY-151824
-
|
ADC Linker
|
Others
|
Boc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent containing an azide group. Used as an orthogonally protected building block in peptide synthesis. Propargyloxycarbonyl, commonly abbreviated as Poc or Pryoc, can either be used as alkyne component for standard Click conjugation or in combination with tetrazine linkers in copper-free Diels-Alder type Click reactions. It also has applications as unusual protecting group for amines, hydroxy functions and as esters. All 3 are stable to neat TFA, but can be cleaved at ambient temperature with Co2(CO)8 in TFA:DCM. Deprotection with other transition metals like palladium have also been reported . Boc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-151837
-
|
ADC Linker
|
Others
|
H-L-Phe(4-NH-Poc)-OH (hydrochloride) is a click chemistry reagent containing an azide group. Used as a modified Phe or Tyr analogue in protein and peptide biosynthesis. Propargyloxycarbonyl, commonly abbreviated as Poc or Pryoc, can either be used as alkyne component for standard Click conjugation or in combination with tetrazine linkers in copper-free Diels-Alder type Click reactions. It also has applications as unusual protecting group for amines, hydroxy functions and as esters. All 3 are stable to neat TFA, but can be cleaved at ambient temperature with Co2(CO)8 in TFA:DCM. Deprotection with other transition metals like palladium have also been reported . H-L-Phe(4-NH-Poc)-OH (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-151856
-
|
ADC Linker
|
Others
|
N3-1,4-cis-CHC-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
-
- HY-151695
-
N2-Fmoc-N6-[(propargyloxy)carbonyl]-L-lysine
|
ADC Linker
|
Others
|
Fmoc-L-Lys(Pryoc)-OH (N2-Fmoc-N6-[(propargyloxy)carbonyl]-L-lysine) is a click chemistry reagent containing an azide group .
|
-
- HY-13718
-
H-Glu-Trp-OH; L-Glutamyl-L-tryptophan
|
VEGFR
HCV
Endogenous Metabolite
|
Infection
Cardiovascular Disease
Inflammation/Immunology
Cancer
|
Oglufanide (H-Glu-Trp-OH) is a dipeptide immunomodulator isolated from calf thymus. Oglufanide inhibits vascular endothelial growth factor (VEGF). Oglufanide can stimulate the immune response to hepatitic C virus (HCV) and intracellular bacterial infections. Oglufanide shows antitumor and anti-angiogenesis activities .
|
-
- HY-151787
-
|
ADC Linker
|
Others
|
Fmoc-L-Lys(N3-Aca-DIM)-OH is a click chemistry reagent containing an azide group. Used as a SPPS building-block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution .
|
-
- HY-W014423S2
-
H-His-OH-13C6 hydrochloride hydrate
|
Endogenous Metabolite
|
Metabolic Disease
|
L-Histidine- 13C6 (hydrochloride hydrate) is the 13C-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
|
-
- HY-W014423S5
-
-
- HY-W002327S
-
|
Isotope-Labeled Compounds
|
Others
|
Fmoc-Asn(Trt)-OH- 13C4, 15N2 is a 15N-labeled and 13C-labled 4-(4-(tert-Butyl)-2-ethoxyphenyl)-2-(2,6-difluorophenyl)-4,5-dihydrooxazole[1].
|
-
- HY-P1591
-
-
- HY-151663
-
Fmoc-Abu(3-N3)-OH (2R,3R)
|
ADC Linker
|
Others
|
Fmoc-Abu(3-N3) (Fmoc-Abu(3-N3)-OH) (2R,3R) is a click chemistry reagent containing an azide group. Fmoc-Abu(3-N3) (2R,3R) can be used for the research of various biochemical .
|
-
- HY-155902B
-
Maleimide-PEG-Hydroxy (MW 1000)
|
Biochemical Assay Reagents
|
Others
|
Mal-PEG-OH (MW 1000) was used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.
|
-
- HY-148642
-
12-hydroxy-NVP; 12-OH-NVP
|
Drug Metabolite
|
Infection
|
12-Hydroxynevirapine (12-hydroxy-NVP; 12-OH-NVP) is a major oxidative metabolite of Nevirapine (HY-10570). Nevirapine is a non-nucleoside reverse transcriptase inhibitor indicated for the HIV-1 infections. Nevirapine causes idiosyncratic hepatotoxicity and mild-to-severe skin rashes. 12-Hydroxynevirapine, a non-reactive metabolite, can be bioactivated by sulphotransferases (SULTs) in the liver and skin, yielding the reactive species 12-Sulphoxy-nevirapine .
|
-
- HY-P1591A
-
-
- HY-155902
-
Maleimide-PEG-Hydroxy (MW 5000)
|
Biochemical Assay Reagents
|
Others
|
Mal-PEG-OH (MW 5000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.
|
-
- HY-155902A
-
Maleimide-PEG-Hydroxy (MW 2000)
|
Biochemical Assay Reagents
|
Others
|
Mal-PEG-OH (MW 2000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.
|
-
- HY-Y1250
-
Fmoc glycine; N-(9-Fluorenylmethoxycarbonyl)glycine; N-Fluorenylmethoxycarbonylglycine; NPC 14692; NSC 334288; [[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]acetic acid
|
Amino Acid Derivatives
|
Others
|
Fmoc-Gly-OH (Fmoc glycine) is a Fmoc-protected glycine derivative, can be used for the synthesis of compounds .
|
-
- HY-W010162
-
L-Alanyl-L-alanine; Ala-Ala
|
Amino Acid Derivatives
|
Others
|
H-Ala-Ala-OH (L-Alanyl-L-alanine; Ala-Ala) is a nonpolar dipeptide that is absorbed by human intestinal Caco-2 cells. The transport of alanine (Ala), like proton/amino acid symport, can lead to cytoplasmic acidification .
|
-
- HY-111330
-
HPF; 3'-p-(Hydroxyphenyl) fluorescein
|
Fluorescent Dye
Reactive Oxygen Species
|
Others
|
Hydroxyphenyl Fluorescein (HPF) is a stable ROS fluorescent probe dye. Hydroxyphenyl Fluorescein has stronger specificity and stability than H2DCFDA (HY-D0940). Hydroxyphenyl Fluorescein can produce strong green fluorescence through hydroxyl radical reaction with intracellular peroxynitroso. Hydroxyphenyl Fluorescein can be applied for fluorescence microscopy, high-throughput imager, luciferase microplate reader or flow cytometry. Ex/Em=490/515 nm .
|
-
- HY-128676
-
H-L-Lys(Poc)-OH hydrochloride
|
Amino Acid Derivatives
|
Cancer
|
N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) hydrochloride is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals . N-ε-propargyloxycarbonyl-L-lysine (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-139014
-
H-L-Lys(Poc)-OH
|
Fluorescent Dye
|
Cancer
|
N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals . N-ε-propargyloxycarbonyl-L-lysine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W014423S3
-
-
- HY-140696C
-
mPEG-Hydroxy (MW 20000); Polyethylene glycol monomethyl ether (MW 20000)
|
PROTAC Linkers
|
Cancer
|
m-PEG-OH (MW 20000) can be used as a macroinitiator to participate in the synthesis of amphiphilic block copolymers. Nanoscale micelles can be prepared by using amphiphilic block copolymers to deliver active drugs. Paclitaxel (HY-B0015), a hydrophobic anticancer agent encapsulated in micelles, has stronger activity in killing cancer cells than free Paclitaxel. And it preferentially accumulates in tumor tissue with only limited distribution in healthy organs.
|
-
- HY-140696D
-
mPEG-Hydroxy (MW 10000); Polyethylene glycol monomethyl ether (MW 10000)
|
PROTAC Linkers
|
Cancer
|
m-PEG-OH (MW 10000) can be used as a macroinitiator to participate in the synthesis of amphiphilic block copolymers. Amphiphilic block copolymers can be used to prepare nanoscale micelles to deliver active drugs. Paclitaxel (HY-B0015), a hydrophobic anticancer agent encapsulated in micelles, has stronger activity in killing cancer cells than free Paclitaxel. And it preferentially accumulates in tumor tissue with only limited distribution in healthy organs.
|
-
- HY-140696E
-
mPEG-Hydroxy (MW 1000); Polyethylene glycol monomethyl ether (MW 1000)
|
PROTAC Linkers
|
Cancer
|
m-PEG-OH (MW 1000) can be used as a macroinitiator to participate in the synthesis of amphiphilic block copolymers. Amphiphilic block copolymers can be used to prepare nanoscale micelles to deliver active drugs. Paclitaxel (HY-B0015), a hydrophobic anticancer agent encapsulated in micelles, has stronger cancer-killing activity than free Paclitaxel. And it accumulates preferentially in tumor tissues and has only limited distribution in healthy organs.
|
-
- HY-N10219
-
|
Tyrosinase
Fungal
|
Infection
|
Dihydroaltenuene B is a potent mushroom tyrosinase inhibitor with an IC50 of 38.33 µM. Dihydroaltenuene B shows the hydrogen bonding interactions between the 3-OH and 4’-OH and the His244, Met280 and Gly281 residues of tyrosinase .
|
-
- HY-W357200
-
N-[9-(6-Hydroxymethyl-4-trityl-morpholin-2-yl)-9H-purin-6-yl]-benzamide
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
N6-Benzoyl-7’-OH-N-trityl morpholino adenine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-W269700S
-
L-Isoleucyl-L-leucine-13C6,15N
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
Ile-(Leu-13C6,15N)-OH (TFA) is 13C- and 15N-labeled L-Isoleucyl-L-leucine (HY-W269700). L-Isoleucyl-L-leucine has a role as a metabolite and can be used to inhibit movement-induced muscle damage and muscle defective condition.
|
-
- HY-131190
-
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
N-Boc-SBP-0636457-OH is a synthesized E3 ligase ligand-linker conjugate that incorporates IAP ligand and a linker. N-Boc-SBP-0636457-OH can be used to design a PROTAC Bcl-xL degrader-1 (HY-131188) .
|
-
- HY-W357201
-
N-[1-(6-Hydroxymethyl-4-trityl-morpholin-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl]-benzamide
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
N4-Benzoyl-7’-OH-N-trityl morpholino cytosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-W014423S1
-
H-His-OH-13C6,15N3,d5 hydrochloride hydrate
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
L-Histidine- 13C6, 15N3,d5 (hydrochloride hydrate) is the deuterium, 13C-, and 15-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
|
-
- HY-107233
-
Prosapogenin CP4
|
Others
|
Others
|
Saponin CP4 is an oleanolic acid derivative which lacks a 23-OH. Saponin CP4 shows no growth inhibition .
|
-
- HY-P2844
-
|
DNA/RNA Synthesis
|
Metabolic Disease
|
Polynucleotide Kinase is a DNA repair enzyme. Polynucleotide Kinase possesses both a 5’-kinase activity that catalyzes the transfer of phosphate from ATP to a 5’-hydroxyl (OH) terminus and also a 3’-phosphatase activity that converts 3’-phosphate termini to 3’-OH termini .
|
-
- HY-W714002
-
|
HIV
Bacterial
|
Infection
|
Feglymycin is a HIV replication inhibitor. Feglymycin is also an antibiotic peptide that has antibacterial activity (MIC: 32-64 μg/mL for Staphylococcus aureus) .
|
-
- HY-12397
-
|
VD/VDR
|
Endocrinology
|
ZK159222, a 25-carboxylic ester analogue of 1α,25-(OH)2D3, is a potent 1α,25-(OH)2D3 receptor (VDR) antagonist. The mechanism of ZK159222 antagonistic action is mediated by a lack of ligand-induced vitamin D receptor interaction with coactivators. ZK159222 has a partial agonistic character .
|
-
- HY-W012340S
-
-
- HY-12398A
-
|
VD/VDR
|
Metabolic Disease
Inflammation/Immunology
|
TEI-9648, a Vitamin D3 Lactone analogue, is a potent and specific vitamin D receptor (VDR) antagonist. TEI-9648 inhibits VDR/VDRE-mediated genomic actions of 1α,25(OH)2D3. TEI-9648 also inhibits HL-60 cell differentiation induced by of 1α,25(OH)2D3. TEI-9648 has the potential for bone metabolism research .
|
-
- HY-131450A
-
|
Others
|
Others
|
(E)-1α,25-Dihydroxyprevitamin D3 is a structurally related analog of 1α,25(OH)2D3 .
|
-
- HY-131887
-
|
Ligands for E3 Ligase
|
Cancer
|
Pomalidomide-C6-COOH is the pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-6-OH can be connected to the ligand for protein by a linker to form PROTAC .
|
-
- HY-18407
-
NMIA
|
Others
|
Others
|
N-Methylisatoic anhydride (NMIA) is a 2'-OH selective acylation agent of RNAs, and is widely used for
resolving secondary RNA structures using the SHAPE (Selective 2'-Hydroxyl Acylation Analyzed by Primer Extension) technology .
|
-
- HY-22295
-
|
Biochemical Assay Reagents
|
Others
|
Fmoc-4-aminobutanoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-12398
-
|
VD/VDR
|
Metabolic Disease
Inflammation/Immunology
|
TEI-9647, a Vitamin D3 Lactone analogue, is a potent and specific vitamin D receptor (VDR) antagonist. TEI-9647 inhibits VDR/VDRE-mediated genomic actions of 1α,25(OH)2D3. TEI-9647 inhibits bone resorption and HL-60 cell differentiation induced by of 1α,25(OH)2D3. TEI-9647 has the potential for suppressing the excessive bone resorption and osteoclast formation in Paget's disease .
|
-
- HY-12407
-
|
VD/VDR
|
Metabolic Disease
|
ZK168281 is a 25-carboxylic ester 1α,25(OH)2D3 analog and a pure VDR antagonist with a Kd value of 0.1 nM. ZK168281 is an effective inhibitor of the coactivator (CoA) interaction of its receptor .
|
-
- HY-135796
-
|
PROTAC Linkers
|
Cancer
|
m-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-130321S1
-
-
- HY-B2048S
-
-
- HY-D0300S1
-
-
- HY-W015339S
-
-
- HY-W134007S
-
-
- HY-W286743S
-
-
- HY-Z3421S
-
-
- HY-W321016S
-
-
- HY-157202
-
-
- HY-149554
-
Bimatoprost dimethyl amide
|
Others
|
Neurological Disease
|
17-Phenyl trinor Prostaglandin F2α dimethyl amide (Bimatoprost dimethyl amide), a 1-OH cyclopentane heptanoic acid, 2-(cycloalkyl or arylalkyl) derivative, is a smooth muscle relaxant. 17-Phenyl trinor Prostaglandin F2α dimethyl amide has the potential for glaucoma research .
|
-
- HY-W002071S
-
-
- HY-Y0869S
-
-
- HY-D1175
-
|
Fluorescent Dye
|
|
Alizarin cyanin green F is an alizarin dye that reacts with calcium possibly via sulfonic acid and/or OH groups.
|
-
- HY-W008129
-
|
Endogenous Metabolite
|
Metabolic Disease
|
cis-4-Hydroxy-D-proline is a precursor of conformationally restricted PNA adenine monomer. cis-4-Hydroxy-D-proline can be used to study the specificity and kinetics of D-alanine dehydrogenase .
|
-
- HY-126916
-
THP-PEG2-OH
|
PROTAC Linkers
|
Cancer
|
Tetrahydropyranyldiethyleneglycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W010719
-
-
- HY-149817
-
|
Cholinesterase (ChE)
|
Neurological Disease
|
AChE-IN-29, 3-OH pyrrolidine derivative, is an cholinesterase (ChE) inhibitor. AChE-IN-29 has cholinesterase inhibitory activity for hAChE, eeAChE and eqBChE with IC50 values of 0.25 μM, 0.23 μM and 0.72 μM, respectively. AChE-IN-29 can be used for the research of Alzheimer's disease .
|
-
- HY-141490
-
|
Others
|
Others
|
Beta-D-Glucopyranosyl nitromethane, as a salt of a strongly basic anion exchanger in the OH cycle, is a glycosyl derivative of nitromethane .
|
-
- HY-N0091S2
-
-
- HY-W278362S
-
-
- HY-Y0978S3
-
-
- HY-116285S
-
-
- HY-124547S
-
-
- HY-W012870
-
|
Biochemical Assay Reagents
|
Others
|
H-DL-HoSer-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-P2848
-
ChOx
|
Endogenous Metabolite
|
Others
|
Cholesterol oxidase, Microorganism (ChOx) is a bacterial flavin oxidase containing FAD, commonly used in biochemical research. Cholesterol oxidase catalyzes the oxidation of the C(3)-OH group of cholesterol (and other sterols) to cholest-5-en-3-one and isomerizes it to cholest-4-en-3-one .
|
-
- HY-113736
-
|
Amino Acid Derivatives
|
Others
|
Glycyllysine is a polypeptide that can be used in the synthesis of antibodies and amino acid type gemini surfactants. Glycyllysine has potential applications in modifying plasmid/gemini/lipid (P/G/L) nanoparticles transport carriers .
|
-
- HY-P4497
-
|
ERK
|
Cancer
|
Prolylserine, a dipeptide, is an inhibitor of melanogenesis production in Mel-Ab cells. Prolylserine decreases expression of microphthalmia-associated transcription factor (MITF) and tyrosinase, induces phorphosylation of ERK, but not cAMP response element binding protein (CREB) .
|
-
- HY-P0018
-
Pepstatin A
|
HIV Protease
Autophagy
|
Infection
Inflammation/Immunology
|
Pepstatin (Pepstatin A) is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin also inhibits HIV protease .
|
-
- HY-P0018A
-
Pepstatin A Trifluoroacetate
|
HIV Protease
Autophagy
|
Infection
Inflammation/Immunology
|
Pepstatin (Pepstatin A) Trifluoroacetate is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin Trifluoroacetate also inhibits HIV protease .
|
-
- HY-P0095
-
|
Angiotensin-converting Enzyme (ACE)
|
Others
|
Acetyl tetrapeptide-5 inhibits glycosylation and ACE-1 activity. Acetyl tetrapeptide-5 reduces edema and relieves vascular pressure by improving the vascular system and strengthening the skin under the eyes. Acetyl tetrapeptide-5 can be used in the research of Antioxidant, anti-aging skin care .
|
-
- HY-W101563S
-
-
- HY-150971
-
|
Pyroptosis
|
Cancer
|
ICy-Q is a quinone oxidoreductase 1 (NQO-1)-activated near-infrared (NIR) reagent which can react with NQO-1 to release the reduction product ICy-OH. ICy-OH selectively induces pancreatic cancer cell death through the pyroptosis pathway. ICy-Q can be used as an effective tool for rapid and accurate diagnosis of intraoperative pathological sections .
|
-
- HY-P0232
-
-
- HY-113089
-
H-Glu(H-Lys-OH)-OH; γ-Glu-ε-Lys
|
Endogenous Metabolite
|
Metabolic Disease
|
Epsilon-(gamma-glutamyl)-lysine is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration .
|
-
- HY-141232
-
HO-PEG10-OH
|
PROTAC Linkers
|
Cancer
|
Decaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141231
-
HO-PEG7-OH
|
PROTAC Linkers
|
Cancer
|
Heptaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141233
-
HO-PEG12-OH
|
PROTAC Linkers
|
Cancer
|
Dodecaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W141910
-
-
- HY-P1116
-
|
Bacterial
|
Infection
Inflammation/Immunology
|
PBP10 is a cell permeable and selective gelsolin-derived peptide inhibitor of formyl peptide receptor 2 (FPR2) over FPR1 . PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity against gram-positive and gram-negative bacteria and limits microbial-induced inflammatory effects .
|
-
- HY-P1116A
-
|
Bacterial
|
Infection
Inflammation/Immunology
|
PBP10 is a cell permeable and selective gelsolin-derived peptide inhibitor of formyl peptide receptor 2 (FPR2) over FPR1 . PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity against gram-positive and gram-negative bacteria and limits microbial-induced inflammatory effects .
|
-
- HY-P4105
-
-
- HY-P10131
-
|
FAP
|
Cancer
|
3BP-3940 is a highly potent fibroblast activation protein (FAP)-targeting peptide for theranostics. 3BP-3940 is often coupled with radionuclides for tumor diagnosis and treatment .
|
-
- HY-W011012S
-
-
- HY-W018386S
-
-
- HY-P4351
-
|
HIV
|
Others
|
HIV-1 gag Protein p24 (194-210) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
-
- HY-135212
-
|
Endogenous Metabolite
|
Metabolic Disease
|
Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound .
|
-
- HY-P4352
-
|
HIV
|
Others
|
HIV-2 Peptide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
-
- HY-W011012S1
-
-
- HY-Y1250S6
-
Fmoc glycine-13C2,15N; N-(9-Fluorenylmethoxycarbonyl)glycine-13C2,15N; N-Fluorenylmethoxycarbonylglycine-13C2,15N; NPC 14692-13C2-15N; NSC 334288-13C2,15N; [[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]acetic acid-13C2,15N
|
Isotope-Labeled Compounds
Influenza Virus
Bacterial
|
Infection
|
Fmoc-Gly-OH- 13C2, 15N is a 15N-labeled and 13C-labled Crystal Violet. Crystal violet (Basic Violet 3) is a triarylmethane dye. Crystal Violet (Gentian Violet) has antiviral effects against H1N1 and also has prominent bactericidal activities.
|
-
- HY-151782
-
|
ADC Linker
|
Others
|
The azide function is widely used for coupling to alkyne-containing fragments via the renowned Click reaction. Polyglycine fragments containing up to 7 glycines are reported to bind to surfaces and have potential application in nanotechnology constructs: constructs of Gly7-NHCH2-fragment containing peptides bind on mica surface in aqueous solution .
|
-
- HY-120277
-
-
- HY-103473
-
-
- HY-N2442
-
|
Reactive Oxygen Species
|
Metabolic Disease
|
Methylophiopogonone B, a homoisoflavonoidal compound that could be isolated from Ophiopogonis Tiber, could scavenge •OH and H2O2 in vitro to a certain extent .
|
-
- HY-E70091
-
|
DNA/RNA Synthesis
|
Others
|
T4 RNA ligase is an ATP-dependent RNA ligase that can catalyze the formation of phosphodiester bonds between the 5'-P end and the 3'-OH end of single-stranded RNA, single-stranded DNA or single nucleotides between molecules or within molecules. T4 RNA ligase is used for enzymatic low ribonucleotide synthesis and 3′ end labeling of RNA. It is mainly used for RNA and RNA, but can also be used for RNA and single nucleotides .
|
-
- HY-10002A
-
1α,25-Dihydroxy-3-epi-vitamin-D3
|
VD/VDR
|
Others
|
(1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion .
|
-
- HY-D1159
-
HKOH-1r
2 Publications Verification
|
Reactive Oxygen Species
Fluorescent Dye
|
Others
|
HKOH-1r is a highly sensitive green fluorescent probe for the specific detection of ·OH in living cells with a maximum excitation wavelength and emission wavelength of 500 nm and 520 nm, respectively .
|
-
- HY-W098722S
-
-
- HY-135179
-
(+)-Biotin-PEG3-OH
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
|
-
- HY-133293
-
HS-PEG5-OH
|
PROTAC Linkers
|
Cancer
|
Thiol-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133294
-
HS-PEG8-OH
|
PROTAC Linkers
|
Cancer
|
Thiol-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133292
-
HS-PEG4-OH
|
PROTAC Linkers
|
Cancer
|
Thiol-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130580
-
HS-PEG6-OH
|
PROTAC Linkers
|
Cancer
|
Thiol-PEG6-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133295
-
HS-PEG10-OH
|
PROTAC Linkers
|
Cancer
|
Thiol-PEG10-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133296
-
HS-PEG9-OH
|
PROTAC Linkers
|
Cancer
|
Thiol-PEG9-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133297
-
HS-PEG12-OH
|
PROTAC Linkers
|
Cancer
|
Thiol-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W040088
-
-
- HY-107364
-
MTX-211
2 Publications Verification
Mol 211
|
EGFR
PI3K
|
Cancer
|
MTX-211 (Mol 211) is a dual inhibitor of EGFR and PI3K with IC50 values of <100 nM. MTX-211 can be used for the research of cancer and other diseases .
|
-
- HY-103473A
-
Boc-Met-Leu-Phe-OH TFA
|
Formyl Peptide Receptor (FPR)
|
Inflammation/Immunology
|
Boc-MLF (TFA) is a peptide, used as a specific formyl peptide receptor (FPR) antagonist, also inhibits the signaling through formyl peptide receptor like 1 (FPRL1) at higher concentrations .
|
-
- HY-W012161
-
-
- HY-141902S
-
-
- HY-157588
-
|
Ligands for E3 Ligase
Autophagy
|
Cancer
|
E3 ligase Ligand-Linker Conjugate 30 is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 ligase Ligand-Linker Conjugate 30 can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
|
-
- HY-135212S
-
|
Endogenous Metabolite
|
Metabolic Disease
|
Hydroxy ipronidazole-d3 is the deuterium labeled Hydroxy ipronidazole. Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound[1].
|
-
- HY-114348
-
DiNAC; (Ac-Cys-OH)2
|
Others
|
Cardiovascular Disease
|
N,N'-diacetyl-L-cystine (DiNAC) is the disulphide dimer of N-acetylcysteine with immunomodulating properties. N,N'-diacetyl-L-cystine is a potent, orally active modulator of contact sensitivity/delayed type hypersensitivity reactions in rodents. N,N'-diacetyl-L-cystine also has antiatherosclerotic effects in Watanabe-heritable hyperlipidemic rabbit (WHHL) rabbits .
|
-
- HY-133298
-
H2N-PEG14-OH
|
PROTAC Linkers
|
Cancer
|
Amino-PEG14-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W007052
-
-
- HY-13249
-
1α-Hydroxy vitamin D4
|
VD/VDR
|
Cancer
|
1alpha-Hydroxy VD4 , a 1alpha(OH)D derivative, can effectively induce the differentiation of monoblastic leukaemia U937, P39/TSU and P31/FUJ cells.
|
-
- HY-136163
-
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
(S,R,S)-AHPC-C2-NH2 dihydrochloride incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. (S,R,S)-AHPC-OH can be used in the synthesis of a series of PROTACs .
|
-
- HY-136621
-
|
5-HT Receptor
|
Neurological Disease
|
5-HT1A modulator 2 hydrochloride, a derivative of 8-OH-DPAT (HY-112061), is a modulator of 5-HT1A with a Ki of 53 nM for 5-HT1A binding .
|
-
- HY-W014423S8
-
|
Endogenous Metabolite
|
Metabolic Disease
|
L-Histidine- 15N3,d5 (hydrochloride hydrate) is the deuterium and 15N labeled L-Histidine hydrochloride hydrate[1]. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
|
-
- HY-111314
-
5-Hydroxy-1-methylhydantoin
|
Others
|
Inflammation/Immunology
|
NZ 419 (5-Hydroxy-1-methylhydantoin) is a metabolite of creatinine and an antioxidant with oral activity, which has the ability to scavenge hydroxyl radicals (•OH). NZ 419 can inhibit the progression of chronic kidney disease (CKD) in rats .
|
-
- HY-D1549
-
|
Fluorescent Dye
|
Others
|
o-Pah is a BODIPY derivative with an -NH2 and -OH substituted meso-Ph group. o-Pah exhibits metal-induced J-aggregation in the presence of Cu 2+ and a specific fluorescence enhancement for Hg 2+ (Ex/Em=483/(495-600) nM) .
|
-
- HY-103687
-
3β-OH-5α-Abi
|
Drug Metabolite
|
Cancer
|
Abiraterone metabolite 1 is a 5β-reduced metabolite of abiraterone. Abiraterone, a steroidal agent, inhibits CYP17A1, blocks androgen synthesis and prolongs survival in prostate cancer.
|
-
- HY-118391
-
N-Benzoyl-L-phenylalanine; Bz-L-Phe-OH
|
Others
|
Others
|
Benzoyl-L-phenylalanine (N-Benzoyl-L-phenylalanine) is a chorisate mutase-prephenate dehydrogenase inhibitor .
|
-
- HY-N0501
-
|
Reactive Oxygen Species
|
Metabolic Disease
|
11-oxo-mogroside V is a natural sweetener that exhibits strong antioxidant activity. It exhibits significant inhibitory effects on reactive oxygen species (O2 -, H2O2 and *OH) with EC50 of 4.79, 16.52, and 146.17 μg/mL, respectively.
|
-
- HY-P2897
-
D-LDH
|
Lactate Dehydrogenase
|
Others
|
D-Lactate dehydrogenase, Microorganism (D-LDH) is an oxidoreductase that uses NAD + or NADP + as an acceptor and acts on the donor CH-OH group, and can catalyze the oxidation of D-lactate to pyruvate. D-Lactate dehydrogenase widely exists in bacteria and fungi, and is often used in biochemical research .
|
-
- HY-111975S1
-
-
- HY-111975S5
-
-
- HY-151930S
-
-
- HY-151930S1
-
-
- HY-N7404
-
Ne-(Trimethyl)-L-lysine chloride; H-Lys(Me)3-OH chloride
|
Endogenous Metabolite
|
Others
|
Nε,Nε,Nε-Trimethyllysine chloride serves as a precursor for gut flora-dependent formation of N,N,N-trimethyl-5-aminovaleric acid (TMAVA) .
|
-
- HY-U00050S
-
E-10-OH-NT-d3
|
Isotope-Labeled Compounds
Drug Metabolite
|
Neurological Disease
|
(E)-10-Hydroxynortriptyline-d3 is a deuterium labeled (E)-10-Hydroxy Nortriptyline. (E)-10-Hydroxy Nortriptyline is a metabolite of Nortriptyline. Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1].
|
-
- HY-113479
-
-
- HY-41919
-
mDPR(boc); (S)-MALEOYL-DPR(BOC)-OH·DCHA
|
ADC Linker
|
Cancer
|
Mal-L-PA-NH-Boc is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-W342499
-
Methyl 3-hydroxytetradecanoate; 3-OH PAME; Methyl 3-hydroxymyristate
|
Others
|
Metabolic Disease
|
3-Hydroxy myristic acid methyl ester (Methyl 3-hydroxytetradecanoate) is the quorum-sensing signal molecule (quormone), which regulates the virulence of Ralstonia solanacearum .
|
-
- HY-42771
-
|
E3 Ligase Ligand-Linker Conjugates
Autophagy
Apoptosis
|
Cancer
|
Thalidomide-4-O-CH2-COO(t-Bu) is t-Bu modified Thalidomide (HY-14658), which is the final step intermediate in the synthesis of Thalidomide-4-OH (HY-123096). Thalidomide-4-O-CH2-COO(t-Bu) acts as a Cereblon ligand to recruit CRBN proteins. The t-Bu protecting group at the end of Thalidomide-4-O-CH2-COO(t-Bu) can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-4-O-CH2-COO(t-Bu) is a key intermediate in the synthesis of CRBN-based designed PROTAC molecules.
|
-
- HY-W015824S2
-
-
- HY-113482S
-
-
- HY-N3810
-
|
Tyrosinase
|
Others
|
ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid is an anti-melanin synthesis tyrosinase inhibitor, which can be isolated from Pteris fern. ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid regulates the melanogenesis transcription factor microphthalmia-associated transcription factor (MITF). The 11α-OH, 15-oxo and 16-en moieties of ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid are key fragments that inhibit melanin synthesis. The 19-COOH moiety has been implicated in the inhibition of cytotoxicity associated with 11α-OH KA and related compounds .
|
-
- HY-Z0615
-
Boc-L-Asp(OBn)-OH
|
Amino Acid Derivatives
|
Others
|
(2S)-4-(Benzyloxy)-2-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid is an aspartic acid derivative .
|
-
- HY-W015824S3
-
-
- HY-P0229
-
Rnase T1
|
DNA/RNA Synthesis
|
Others
|
Ribonulease T1, Aspergillus oryzae (Rnase T1), is commonly used in biochemical research. Ribonuclease T1 is an endonuclease that can specifically degrade single stranded RNA. Ribonuclease T1 can form nucleoside 2 ', 3 '-cyclic phosphoric acid intermediates to cut the phosphodiester bond between 3' -guanosine residues and adjacent nucleoside 5 '-OH groups to produce 3' -GMP terminal oligonucleotides .
|
-
- HY-D1200
-
Solvent Green 1
|
Fungal
Parasite
|
Others
|
Malachite Green Carbinol base (MGOH, MGCB) is a derivative of Malachite green (MG) with not fluorescence. Malachite green carbinol base (MGOH, MGCB), as a pH regulation reagent,MGCB molecule could release OH - under UV light irradiation and generate a progressive shift in pH values. MGCB solution turns from colorless to deep green rapidly when exposed to a high-pressure UV lamp (500 W, 50 W/cm) .
|
-
- HY-W015824S1
-
-
- HY-W015824S5
-
-
- HY-W010507
-
Methyl (R)-(-)-3-hydroxybutyrate
|
Biochemical Assay Reagents
|
Others
|
(R)-Methyl 3-hydroxybutanoate, (R)-Methyl 3-hydroxybutanoate is an enantiomer, from the perspective of the methyl (-CH3) group, the hydroxyl (-OH) group on the third carbon atom The group faces to the right, a colorless transparent liquid, soluble in organic solvents such as ethanol and ether, insoluble in water, (R)-Methyl 3-hydroxybutanoate is usually used to synthesize various organic compounds (including drugs, agricultural chemicals and flavoring agents) It can also be used as a chiral auxiliary in asymmetric synthetic reactions involving the formation of chemical bonds in a stereoselective manner.
|
-
- HY-113031S
-
-
- HY-146659S
-
3-(Phenylthio)-DL-alanine; H-DL-Cys(Ph)-OH-d2
|
Isotope-Labeled Compounds
|
|
S-Phenyl-DL-cysteine-3,3-d2 is the deuterium labeled S-Phenyl-DL-cysteine-3,3[1].
|
-
- HY-N7404S
-
Ne-(Trimethyl)-L-lysine-d9 chloride; H-Lys(Me)3-OH-d9 chloride
|
Endogenous Metabolite
|
Others
|
Nε,Nε,Nε-Trimethyllysine-d9 (chloride) is the deuterium labeled Nε,Nε,Nε-Trimethyllysine (chloride)[1]. Nε,Nε,Nε-Trimethyllysine chloride serves as a precursor for gut flora-dependent formation of N,N,N-trimethyl-5-aminovaleric acid (TMAVA)[2].
|
-
- HY-W190943
-
|
Drug-Linker Conjugates for ADC
|
Cancer
|
Azido-PEG4-Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the cleavable linker Azido-PEG4-Val-Cit-PAB-OH . Azido-PEG4-Val-Cit-PAB-MMAE is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-144392
-
|
Cholinesterase (ChE)
|
Neurological Disease
|
AChE/BuChE-IN-1 (Compound 1), a chrysin derivative, is a selective butyrylcholinesterase (BuChE) inhibitor with an IC50 of 0.48 μM. AChE/BuChE-IN-1 inhibits acetylcholinesterase (AChE) with an IC50 of 7.16 μM. AChE/BuChE-IN-1 shows strong scavenging ·OH activities with a IC50 of 0.1674 μM. AChE/BuChE-IN-1 inhibits reactive oxygen species (ROS), Aβ1-42 aggregation (self-, Cu2+-induced, AChE-induced). AChE/BuChE-IN-1 has high BBB permeability and bioavailability and low cell toxicity. AChE/BuChE-IN-1 has the potential for Alzheimer' disease (AD) research .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-D1151
-
|
Fluorescent Dyes/Probes
|
HKOH-1 is a highly sensitive green fluorescent probe for the specific detection of ·OH in living cells with a maximum excitation wavelength and emission wavelength of 500 nm and 520 nm, respectively .
|
-
- HY-W142117
-
-
- HY-12362G
-
|
Fluorescent Dye
|
Val-cit-PAB-OH GMP is a GMP grade Val-cit-PAB-OH (HY-12362). Val-cit-PAB-OH is a degradable ADC linker.
|
-
- HY-131833G
-
|
Fluorescent Dye
|
Fmoc-Gly-Gly-Phe-OH GMP is a GMP grade Fmoc-Gly-Gly-Phe-OH (HY-131833). Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-P2614
-
-
- HY-P2616
-
|
Chromogenic Substrates
|
Mca-YVADAP-Lys(Dnp)-OH is a fluorogenic substrate for caspase-1 and angiotensin-converting enzyme 2 (ACE2) .
|
-
- HY-78921AG
-
|
Fluorescent Dye
|
Fmoc-3VVD-OH (GMP) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-P2536
-
|
Fluorescent Dyes/Probes
|
Mca-Ala-Pro-Lys(Dnp)-OH, a specific ACE2 quenched fluorogenic substrate, can be used to detect ACE2 activity, such as urinary, heart and lung .
|
-
- HY-111330
-
HPF; 3'-p-(Hydroxyphenyl) fluorescein
|
Fluorescent Dyes/Probes
|
Hydroxyphenyl Fluorescein (HPF) is a stable ROS fluorescent probe dye. Hydroxyphenyl Fluorescein has stronger specificity and stability than H2DCFDA (HY-D0940). Hydroxyphenyl Fluorescein can produce strong green fluorescence through hydroxyl radical reaction with intracellular peroxynitroso. Hydroxyphenyl Fluorescein can be applied for fluorescence microscopy, high-throughput imager, luciferase microplate reader or flow cytometry. Ex/Em=490/515 nm .
|
-
- HY-D1175
-
|
Dyes
|
Alizarin cyanin green F is an alizarin dye that reacts with calcium possibly via sulfonic acid and/or OH groups.
|
-
- HY-D1159
-
HKOH-1r
2 Publications Verification
|
Fluorescent Dyes/Probes
|
HKOH-1r is a highly sensitive green fluorescent probe for the specific detection of ·OH in living cells with a maximum excitation wavelength and emission wavelength of 500 nm and 520 nm, respectively .
|
-
- HY-D1549
-
|
Dyes
|
o-Pah is a BODIPY derivative with an -NH2 and -OH substituted meso-Ph group. o-Pah exhibits metal-induced J-aggregation in the presence of Cu 2+ and a specific fluorescence enhancement for Hg 2+ (Ex/Em=483/(495-600) nM) .
|
Cat. No. |
Product Name |
Type |
-
- HY-W013851
-
|
Chelators
|
EDTA-OH is a chelating agent, which forms thermodynamically stable chelates with metal ions like calcium, magnesium, iron, zinc and copper . EDTA-OH exhibits ability of phytoremediation in heavy-metal-contaminated soils . EDTA-OH is able to cross brain-blood barrier .
|
-
- HY-W007618
-
|
Amino acids and Derivatives
|
Boc-Lys-OH is a lysine derivative of azocyclic and anthraquinone. Boc-Lys-OH is a polypeptide-based heterofunctional linking molecule, which can be used as a biomarker reagent .
|
-
- HY-W088147
-
Z-2-Nal-OH
|
Biochemical Assay Reagents
|
Z-L-2-Nal-OH (Z-2-Nal-OH) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-12362G
-
|
Biochemical Assay Reagents
|
Val-cit-PAB-OH GMP is a GMP grade Val-cit-PAB-OH (HY-12362). Val-cit-PAB-OH is a degradable ADC linker.
|
-
- HY-131833G
-
|
Biochemical Assay Reagents
|
Fmoc-Gly-Gly-Phe-OH GMP is a GMP grade Fmoc-Gly-Gly-Phe-OH (HY-131833). Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-158285
-
|
Biochemical Assay Reagents
|
25-OH Vitamin D3/BSA is one of protein/peptide and small molecule drug conjugates (PDCs), consisting of 25-OH Vitamin D3 () and BSA. PCDs are promising targeted therapeutics with better cell permeability and drug selectivity than antibody-drug conjugates (ADCs). PDCs have been widely used in research on cancer, COVID-19, and metabolic diseases .
|
-
- HY-W002327
-
|
Biochemical Assay Reagents
|
Fmoc-Asn(Trt)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Fmoc-Asn(Trt)-OH can be used for synthesis of Fmoc-based solid-phase peptide synthesis .
|
-
- HY-W009229
-
-
- HY-140741
-
|
Drug Delivery
|
DSPE-PEG-OH, MW 2000 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Additionally, DSPE-PEG-OH, MW 2000 can also be used for drug delivery .
|
-
- HY-W008325
-
|
Biochemical Assay Reagents
|
Boc-L-Dap-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W013081
-
|
Biochemical Assay Reagents
|
Fmoc-Gln(Trt)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W010856
-
|
Biochemical Assay Reagents
|
Fmoc-Orn(Boc)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W008034
-
|
Biochemical Assay Reagents
|
Fmoc-L-Trp(Boc)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-78921AG
-
|
Biochemical Assay Reagents
|
Fmoc-3VVD-OH (GMP) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W008205
-
Fmoc-L-Hydroxyproline
|
Biochemical Assay Reagents
|
Fmoc-Hyp-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W008963
-
Nα-Fmoc-D-tryptophan; Fmoc-D-Trp-OH
|
Biochemical Assay Reagents
|
Fmoc-D-Trp-OH (Nα-Fmoc-D-tryptophan) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-W007743
-
Boc-L-pipecolic acid
|
Biochemical Assay Reagents
|
Boc-Pip-OH (Boc-L-pipecolic acid) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W009673
-
N-Boc-L-pyroglutamic acid
|
Biochemical Assay Reagents
|
Boc-Pyr-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W013473
-
Boc-D-Pipecolic acid
|
Biochemical Assay Reagents
|
Boc-D-HoPro-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W008753
-
N-Cbz-L-valine
|
Biochemical Assay Reagents
|
Z-L-Val-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W008689
-
N-Fmoc-6-AminOHexanoic acid
|
Biochemical Assay Reagents
|
Fmoc-ε-Acp-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W111141
-
endo-9-Hydroxymethylbicyclo[6.1.0]non-4-yne
|
Biochemical Assay Reagents
|
BCN-OH (endo-9-Hydroxymethylbicyclo[6.1.0]non-4-yne) is a mitochondrial probe based on the lyophilic bidentate bicyclic ligand BCN and is a control reagent for BCN-TPP. The TPP group is a reactive sulfenic acid probe that targets mitochondria. BCN-TPP is known to affect mitochondrial energy, causing a sharp decrease in basal respiration, causing it to exhibit faster reaction kinetics with sulfonated proteins. BCN-OH does not contain hydrophobic triphenylphosphonium (TPP) ions. Using BCN-OH as a control allows the TPP group to be safely introduced when designing sulfenic acid traps .
|
-
- HY-W145646
-
|
Biochemical Assay Reagents
|
Fmoc-L-Ser((Ac)4-β-D-Glc)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W015236
-
Triglycine
|
Biochemical Assay Reagents
|
H-Gly-Gly-Gly-OH, also known as Triglycine, is a tripeptide composed of glycine, glycine and glycine, which are linked by peptide bonds. Often used as a model compound in the study of protein structure and function. Glycylglycylglycine also acts as a neurotransmitter in the central nervous system and has been shown to have antioxidant properties. Furthermore, it may have potential research roles in various diseases such as cancer, diabetes and neurodegenerative diseases.
|
-
- HY-155902B
-
Maleimide-PEG-Hydroxy (MW 1000)
|
Drug Delivery
|
Mal-PEG-OH (MW 1000) was used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.
|
-
- HY-155902
-
Maleimide-PEG-Hydroxy (MW 5000)
|
Drug Delivery
|
Mal-PEG-OH (MW 5000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.
|
-
- HY-155902A
-
Maleimide-PEG-Hydroxy (MW 2000)
|
Drug Delivery
|
Mal-PEG-OH (MW 2000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.
|
-
- HY-W010162
-
L-Alanyl-L-alanine; Ala-Ala
|
Biochemical Assay Reagents
|
H-Ala-Ala-OH (L-Alanyl-L-alanine; Ala-Ala) is a nonpolar dipeptide that is absorbed by human intestinal Caco-2 cells. The transport of alanine (Ala), like proton/amino acid symport, can lead to cytoplasmic acidification .
|
-
- HY-140696C
-
mPEG-Hydroxy (MW 20000); Polyethylene glycol monomethyl ether (MW 20000)
|
Drug Delivery
|
m-PEG-OH (MW 20000) can be used as a macroinitiator to participate in the synthesis of amphiphilic block copolymers. Nanoscale micelles can be prepared by using amphiphilic block copolymers to deliver active drugs. Paclitaxel (HY-B0015), a hydrophobic anticancer agent encapsulated in micelles, has stronger activity in killing cancer cells than free Paclitaxel. And it preferentially accumulates in tumor tissue with only limited distribution in healthy organs.
|
-
- HY-140696D
-
mPEG-Hydroxy (MW 10000); Polyethylene glycol monomethyl ether (MW 10000)
|
Drug Delivery
|
m-PEG-OH (MW 10000) can be used as a macroinitiator to participate in the synthesis of amphiphilic block copolymers. Amphiphilic block copolymers can be used to prepare nanoscale micelles to deliver active drugs. Paclitaxel (HY-B0015), a hydrophobic anticancer agent encapsulated in micelles, has stronger activity in killing cancer cells than free Paclitaxel. And it preferentially accumulates in tumor tissue with only limited distribution in healthy organs.
|
-
- HY-140696E
-
mPEG-Hydroxy (MW 1000); Polyethylene glycol monomethyl ether (MW 1000)
|
Drug Delivery
|
m-PEG-OH (MW 1000) can be used as a macroinitiator to participate in the synthesis of amphiphilic block copolymers. Amphiphilic block copolymers can be used to prepare nanoscale micelles to deliver active drugs. Paclitaxel (HY-B0015), a hydrophobic anticancer agent encapsulated in micelles, has stronger cancer-killing activity than free Paclitaxel. And it accumulates preferentially in tumor tissues and has only limited distribution in healthy organs.
|
-
- HY-P2844
-
|
Biochemical Assay Reagents
|
Polynucleotide Kinase is a DNA repair enzyme. Polynucleotide Kinase possesses both a 5’-kinase activity that catalyzes the transfer of phosphate from ATP to a 5’-hydroxyl (OH) terminus and also a 3’-phosphatase activity that converts 3’-phosphate termini to 3’-OH termini .
|
-
- HY-22295
-
|
Biochemical Assay Reagents
|
Fmoc-4-aminobutanoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W012870
-
|
Biochemical Assay Reagents
|
H-DL-HoSer-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W010507
-
Methyl (R)-(-)-3-hydroxybutyrate
|
Biochemical Assay Reagents
|
(R)-Methyl 3-hydroxybutanoate, (R)-Methyl 3-hydroxybutanoate is an enantiomer, from the perspective of the methyl (-CH3) group, the hydroxyl (-OH) group on the third carbon atom The group faces to the right, a colorless transparent liquid, soluble in organic solvents such as ethanol and ether, insoluble in water, (R)-Methyl 3-hydroxybutanoate is usually used to synthesize various organic compounds (including drugs, agricultural chemicals and flavoring agents) It can also be used as a chiral auxiliary in asymmetric synthetic reactions involving the formation of chemical bonds in a stereoselective manner.
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P4071
-
Cathelicidin-OH antimicrobial peptide
|
Bacterial
|
Infection
|
OH-CATH is a natural antimicrobial peptide that can be isolated from the venom and tissue of Ophiophagus hannah (King Cobra) .
|
-
- HY-P4439
-
|
Amino Acid Derivatives
|
Neurological Disease
|
H-Met-Val-OH is a dipeptide containing free N-terminal methionine. H-Met-Val-OH exhibits activity against cDNA expressing Flavin-containing monooxygenase (FMO) 1 and FMO3. H-Met-Val-OH has potential applications in the growth of neuritis .
|
-
- HY-P4554
-
|
Endogenous Metabolite
|
Metabolic Disease
|
H-Phe-Arg-OH is a dipeptide containing phenylalanine and arginine. H-Phe-Arg-OH can be separated from Bradykinin (HY-P0206) through Angiotensin-converting enzyme (ACE, HY-P2983). H-Phe-Arg-OH can be used for metabolic research .
|
-
- HY-P4553
-
|
Amino Acid Derivatives
|
Others
|
H-Met-Pro-OH is a dipeptide containing methionine and proline. H-Met-Pro-OH is a substrate for aminopeptidase P (APP) and skin fibroblast prolidase .
|
-
- HY-P4648
-
|
Bacterial
|
Infection
|
H-Trp-Trp-Trp-OH is a tripeptide consisting of tryptophan. H-Trp-Trp-Trp-OH has antibacterial activity .
|
-
- HY-P4531
-
|
Opioid Receptor
|
Neurological Disease
|
H-Ser-Tyr-OH is a dipeptide consisting of glutamic acid, glycine and histidine. H-Ser-Tyr-OH can form a copper(II) complex with copper ions to form a strong free radical scavenging activity. H-Ser-Tyr-OH also increases the intracellular uptake of the delta opioid receptor ligand deltorphin .
|
-
- HY-P4654
-
-
- HY-P4296
-
|
Amino Acid Derivatives
|
Others
|
H-Gly-Sar-Sar-OH is an orally active tripeptide. H-Gly-Sar-Sar-OH is transported through PepT1 within Caco-2 cells. H-Gly Sar Sar OH has potential applications in material transportation .
|
-
- HY-P4438
-
-
- HY-P4287
-
|
Amino Acid Derivatives
|
Others
|
H-Gly-Lys-Gly-OH is a tripeptide containing glycine and lysine. H-Gly-Lys-Gly-OH can be used for the synthesis of casein and soybean protein .
|
-
- HY-P4846
-
|
CXCR
|
Inflammation/Immunology
|
Ac-Pro-Gly-Pro-OH is an endogenous degradation product of extracellular collagen and can be used as CXCR2 agonist. Ac-Pro-Gly-Pro-OH elicits bactericidal activity and inhibits lung inflammation, reducing immune cell apoptosis. Ac-Pro-Gly-Pro-OH enhances the production of type 1 cytokines (IFN-γ and IL-12) but inhibits the production of proinflammatory cytokines. Ac-Pro-Gly-Pro-OH has the potential for the research of sepsis .
|
-
- HY-P4483
-
|
Peptides
|
Others
|
H-Pro-Arg-OH is a dipeptide composed of proline and arginine.
|
-
- HY-P4486
-
|
Peptides
|
Others
|
H-Pro-Gly-Pro-OH is a collagen-derived matrikine that has classically been described as a neutrophil chemoattractant. H-Pro-Gly-Pro-OH is perfectly positioned to focus neutrophils on the site required and direct a localized repair response. H-Pro-Gly-Pro-OH activates the transcription of neurotrophins and their receptor genes after cerebral ischemia .
|
-
- HY-P4294
-
|
Amino Acid Derivatives
|
Others
|
H-Gly-Pro-Gly-OH is a tripeptide containing glycine and proline. H-Gly-Pro-Gly-OH can be used for the synthesis of other polypeptides, such as (Pro Gly Gly)n .
|
-
- HY-P4383
-
|
Peptides
|
Others
|
H-Leu-Leu-Ala-OH is a tripeptide composed of two L-leucine units joined to L-alanine by a peptide linkage. H-Leu-Leu-Ala-OH shows antioxidant activities .
|
-
- HY-P4495
-
-
- HY-P4513
-
-
- HY-P4840
-
|
Peptides
|
Others
|
Ac-Phe-Lys-OH is a inverted Aspartame type sweetener .
|
-
- HY-P4393
-
|
Aminopeptidase
|
Others
|
H-Leu-Trp-Met-Arg-OH is a tetrapeptide. H-Leu-Trp-Met-Arg-OH can be used as a substrate for aminopeptidase-mediated hydrolysis studies .
|
-
- HY-P4551
-
-
- HY-P4641
-
|
Angiotensin-converting Enzyme (ACE)
|
Cardiovascular Disease
|
H-Trp-Phe-OH is a dipeptide consisting of tryptophan and phenylalanine (Trp-Phe). H-Trp-Phe-OH is also an antihypertensive peptide with inhibitory activity on angiotensin-converting enzyme (ACE), dose-dependently increases NO levels, and decreases endothelin-1 (ET-1) levels. H-Trp-Phe-OH (2 mg/kg; subcutaneous injection; 6 injections over 3 days) causes an increase in ovarian weight in female mice .
|
-
- HY-P4300
-
-
- HY-P4437
-
-
- HY-P4659
-
|
Peptides
|
Others
|
H-Val-Arg-OH is a dipeptide consisting of valine and arginine, used in biochemical research .
|
-
- HY-P4231
-
-
- HY-P4420
-
-
- HY-P4384
-
|
Peptides
|
Others
|
H-Leu-Ser-OH is a dipeptide formed from L-leucine and L-serine residues and is a metabolite .
|
-
- HY-P5037
-
|
Peptides
|
Others
|
Fmoc-Gly-Pro-Hyp-OH is a tripeptide that can be used in peptide synthesis .
|
-
- HY-P4431
-
|
Amino Acid Derivatives
|
Others
|
H-Met-Asp-OH is a dipeptide containing methionine and aspartic acid, which can be used for the synthesis of polypeptides .
|
-
- HY-P4479
-
|
Peptides
|
Others
|
H-Phe-Phe-Phe-OH is an aromatic tripeptide that has the potential to be used as DNA molecular probe .
|
-
- HY-P4488
-
|
Peptides
|
Others
|
H-Pro-Pro-Gln-OH is a oligopeptide with excellent dipeptidyl peptidase-IV (DPP-IV) inhibitory activity .
|
-
- HY-P5037A
-
|
Peptides
|
Others
|
Fmoc-Gly-Pro-Hyp-OH TFA is a tripeptide that can be used in peptide synthesis .
|
-
- HY-P4322
-
|
ERK
Akt
|
Neurological Disease
Cancer
|
H-Ile-Lys-Val-Ala-Val-OH is one of the most potent active sites of laminin-1. H-Ile-Lys-Val-Ala-Val-OH promotes cell adhesion, neurite outgrowth, and tumor growth. H-Ile-Lys-Val-Ala-Val-OH stimulates BMMSC population growth and proliferation by activating MAPK/ERK1/2 and PI3K/Akt signalling pathways .
|
-
- HY-P4309
-
|
Peptides
|
Others
|
H-Gly-Tyr-Gly-OH, a tyrosine tripeptide, can be found in structural and transport proteins such as collagen and ion channels .
|
-
- HY-P5962
-
|
Peptides
|
Others
|
Fmoc-Gly-Pro-Hyp(OtBu)-OH (TFA) is a tripeptide that can be used in peptide synthesis .
|
-
- HY-P4480
-
|
Peptides
|
Others
|
H-Phe-Phe-Phe-Phe-OH is a tetrapeptide that can generate vertically aligned, highly ordered 3-D bionanostructures .
|
-
- HY-P4232
-
|
Peptides
|
Others
|
H-Gly-Arg-Ala-Asp-Ser-Pro-OH (GRADSP) is a negative control peptide of GRGDdSP .
|
-
- HY-P4286
-
|
Peptides
|
Cancer
|
H-Gly-Leu-Phe-OH (GLF), an immunostimulatory tripeptide derived from α-lactalbumin, inhibits anticancer agent Etoposide-induced alopecia, epidermal thickening, and thinning of the adipocyte layer .
|
-
- HY-P4505
-
|
Peptides
|
Others
|
H-Ser-Gln-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
-
- HY-P4311
-
|
Peptides
|
Others
|
H-His-Glu-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
-
- HY-P4321
-
|
Peptides
|
Others
|
H-Ile-His-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
-
- HY-P4226
-
|
Peptides
|
Others
|
H-Glu-Val-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
-
- HY-P4382
-
|
Peptides
|
Others
|
H-Leu-His-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
-
- HY-P4377
-
|
Peptides
|
Others
|
H-Leu-Asp-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
-
- HY-P4374
-
|
Peptides
|
Others
|
H-Leu-Asn-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
-
- HY-P4435
-
|
Peptides
|
Others
|
H-Met-His-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
-
- HY-P4472
-
|
Peptides
|
Others
|
H-Phe-Asp-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
-
- HY-P4473
-
|
Peptides
|
Others
|
H-Phe-Ile-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
-
- HY-P4478
-
|
Peptides
|
Others
|
H-Phe-Met-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
-
- HY-P4412
-
|
Peptides
|
Others
|
H-Lys-Asp-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4415
-
|
Peptides
|
Others
|
H-Lys-Gly-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4423
-
|
Peptides
|
Others
|
H-Lys-Val-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4424
-
|
Peptides
|
Others
|
H-Met-Arg-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4430
-
|
Peptides
|
Others
|
H-Met-Asn-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4396
-
|
Peptides
|
Others
|
H-Lys-Arg-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4436
-
|
Peptides
|
Others
|
H-Met-Lys-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4434
-
|
Peptides
|
Others
|
H-Met-Glu-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4485
-
|
Peptides
|
Others
|
H-Pro-Asn-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4499
-
|
Peptides
|
Others
|
H-Ser-Ala-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4509
-
|
Peptides
|
Others
|
H-Ser-Phe-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4512
-
|
Peptides
|
Others
|
H-Ser-Ser-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4501
-
|
Peptides
|
Others
|
H-Ser-Asp-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4624
-
|
Peptides
|
Others
|
H-Thr-Met-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4622
-
|
Peptides
|
Others
|
H-Thr-Gly-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4660
-
|
Peptides
|
Others
|
H-Val-Asp-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4317
-
|
Peptides
|
Others
|
H-His-Trp-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4545
-
|
Peptides
|
Others
|
Abz-Gly-p-nitro-Phe-Pro-OH is the fluorescent substrate angiotensin I converting enzyme (ACE-I) with 355 nm excitation and 405 nm emission wavelengths .
|
- HY-P4481
-
|
Peptides
|
Others
|
H-Phe-Phe-Phe-Phe-Phe-OH has a self-assembled structure, which can be assembled into an ordered autofluorescent elongated structure, showing mechanochromic properties .
|
- HY-P4225
-
|
Peptides
|
Others
|
H-Glu-Tyr-Glu-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4387
-
|
Peptides
|
Others
|
H-Leu-Ser-Phe-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4234
-
|
Peptides
|
Others
|
H-Gly-Asp-Gly-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4235
-
|
Peptides
|
Others
|
H-Gly-Cys-Gly-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4271
-
|
Peptides
|
Others
|
H-Gly-Gly-Lys-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4273
-
|
Peptides
|
Others
|
H-Gly-Gly-Met-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4433
-
|
Peptides
|
Others
|
H-Met-D-Met-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P5045
-
|
Peptides
|
Inflammation/Immunology
Cancer
|
Fmoc-Thr(GalNAc(Ac)3-β-D)-OH inhibits cancer cell growth, through targeting intricate cancer-specific pathways while simultaneously strengthening immunologic response .
|
- HY-114437
-
Z-D-Phe-Phe-Gly-OH; FIP; Virus Replication Inhibitory Peptide
|
Influenza Virus
|
Infection
|
Fusion Inhibitory Peptide (Z-D-Phe-Phe-Gly-OH, FIP, Virus Replication Inhibitory Peptide) is a potent inhibitor of the virus replication, by inhibiting the membrane fusing activity of a viral glycoprotein .
|
- HY-145779
-
- HY-W010770
-
- HY-P4267
-
|
Peptides
|
Others
|
H-Gly-Gly-Arg-Ser-Pro-Ala-Met-Pro-Glu-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-41121
-
Boc-Ala-OH
|
Amino Acid Derivatives
|
Others
|
Boc-L-Ala-OH (Boc-Ala-OH) shows excellent affinity with ATP. Boc-L-Ala-OH contains an amino acid moiety, and an acylamide bond like that of the peptide and protein .
|
- HY-W142161
-
Fmoc-MeHis(Trt)-OH
|
Amino Acid Derivatives
|
Others
|
Fmoc-N-Me-His(Trt)-OH (Fmoc-MeHis(Trt)-OH) is a is an amino acid derivative containing amino and carboxyl groups. Fmoc-N-Me-His(Trt)-OH for the synthesis of Fmoc-MeHis (Trt) -Leu-OH .
|
- HY-P4550
-
|
Endogenous Metabolite
|
Metabolic Disease
|
H-Hyp-Gly-OH is a dipeptide containing hydroxyproline and glycine. H-Hyp-Gly-OH promotes the growth of mouse primary fibroblasts on collagen gel. H-Hyp-Gly-OH has potential applications in improving skin by ingesting hydrolyzed collagen. H-Hyp-Gly-OH can be used for metabolic research .
|
- HY-W040067
-
- HY-W008487
-
- HY-W010836
-
- HY-W010811
-
- HY-78843
-
- HY-66026
-
- HY-66025
-
- HY-P10173
-
|
Angiotensin-converting Enzyme (ACE)
|
Others
|
Abz-LFK(Dnp)-OH is an angiotensin I-converting enzyme (ACE) peptide substrate. Abz-LFK(Dnp)-OH is selective for the C domain of ACE. Abz-LFK(Dnp)-OH can be used to assess ACE activity .
|
- HY-P10070
-
|
Peptides
|
Others
|
Ac-pSar16-OH is a polysarcosine which can replace PEG for therapeutic protein conjugation .
|
- HY-W007618
-
|
Peptides
|
Others
|
Boc-Lys-OH is a lysine derivative of azocyclic and anthraquinone. Boc-Lys-OH is a polypeptide-based heterofunctional linking molecule, which can be used as a biomarker reagent .
|
- HY-P10069
-
|
Peptides
|
Others
|
Ac-pSar12-OH, as a linker, can be used for preparation of Ligand-Drug-Conjugate (LDC) .
|
- HY-136432
-
Mc-GGFG-PAB-OH
|
ADC Linker
|
Cancer
|
Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
|
- HY-P3716
-
|
Peptides
|
Others
|
H(-Asn-Pro-Asn-Ala)2-OH is an active petide. H(-Asn-Pro-Asn-Ala)2-OH can be used for the research of various biochemical .
|
- HY-W048209
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Lys(Palmitoyl)-OH is a Fmoc-amino acid with long alkyl chains. Fmoc-Lys(Palmitoyl)-OH can be used for peptide synthesis .
|
- HY-W010838
-
- HY-W142086
-
- HY-104004A
-
Fmoc-Ser-(GalNAc(Ac)3-beta-D)-OH; Fmoc-Ser[GalNAc(Ac)3-β-D]-OH; Fmoc-Ser(Ac3AcNH-β-Gal)-OH
|
Amino Acid Derivatives
|
Others
|
Fmoc-Ser(O-β-D-GalNAc(OAc)3)-OH is a serine derivative .
|
- HY-W013190
-
- HY-W009003
-
- HY-W009005
-
- HY-W009085
-
- HY-W009088
-
- HY-W009337
-
- HY-23424
-
- HY-42065
-
- HY-W010793
-
- HY-I1107
-
- HY-W142023
-
- HY-W007720
-
- HY-W007842
-
- HY-W008176
-
- HY-W008233
-
- HY-W008696
-
- HY-W011000
-
- HY-W011081
-
- HY-W011423
-
- HY-W011703
-
- HY-W012137
-
- HY-W012437
-
- HY-W012446
-
- HY-W011359
-
- HY-W007931
-
- HY-W006093
-
- HY-79648
-
- HY-79131
-
- HY-W009339
-
- HY-W009204
-
- HY-W009151
-
- HY-W013780
-
- HY-W013280
-
- HY-W142071
-
- HY-W142117
-
|
Fluorescent Dye
|
Others
|
H-Asp(AMC)-OH, a amino acid derivative, is a fluorescent dye. H-Asp(AMC)-OH dose not inhibit glycine transport at a concentration of 0.25 mM .
|
- HY-79128
-
Fmoc-L-Lys(Boc)-OH; Fmoc-Lys(Boc)-OH; N-α-(Fmoc)-N-ε-(t-boc)-L-Lysine-OH
|
Amino Acid Derivatives
|
Others
|
Fmoc-L-Lys (Boc)-OH is a lysine derivative .
|
- HY-139468
-
- HY-W010982
-
- HY-W048671
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Thr(TBDMS)-OH is a Threonine derivative. Fmoc-Thr(TBDMS)-OH can be used for the preparation of sugar ligand-tethered functional nucleic acid conjugates for targeted research .
|
- HY-W010712
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation .
|
- HY-W013123
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-D-Phe(4-CF3)-OH is Phenylalanine derivative. Fmoc-D-Phe(4-CF3)-OH can be used for the research of peptide inhibitors of protein-protein interactions .
|
- HY-136432A
-
Mc-GGFG-PAB-OH TFA
|
ADC Linker
|
Cancer
|
Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) TFA is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
|
- HY-P4844
-
|
Peptides
|
Others
|
Ac-Phe-Phe-OH is a negatively charged analogue of the diphenylalanine peptide that forms large aggregates when combined with the NH2-Phe-Phe-OH peptide .
|
- HY-P4248
-
- HY-P4255
-
- HY-P4262
-
- HY-P4595
-
- HY-P4596
-
- HY-P4603
-
- HY-P4604
-
- HY-P4607
-
- HY-P4608
-
- HY-P4609
-
- HY-P4610
-
- HY-P4955
-
- HY-P4598
-
- HY-P10172
-
- HY-P4530
-
|
Peptides
|
Others
|
D-Ala-Gly-Gly-OH is a peptide substrate. DppA has a poor efficiency on peptide substrates D-Ala-Gly-Gly-OH .
|
- HY-P4559
-
|
Peptides
|
Others
|
H-Pro-Met-OH is a dipeptide containing proline and methionine, which can serve as a substrate for prolinase. H-Pro-Met-OH can also be used for the synthesis of polypeptides .
|
- HY-W011210
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Pra-OH is a Glycine (HY-Y0966) derivative . Fmoc-Pra-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-Y1636
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis) .
|
- HY-P4558
-
|
Peptides
|
Others
|
H-Pro-Lys-OH is a dipeptide containing proline and lysine, which can serve as a substrate for iminodipeptidase (prolinase). H-Pro-Lys-OH can also be used for the synthesis of polypeptides .
|
- HY-W008371
-
- HY-W013286
-
- HY-Z0438
-
- HY-I0931
-
- HY-P4599
-
- HY-137416
-
- HY-W014405
-
- HY-P4579
-
|
Peptides
|
Others
|
Pyr-Phe-OH is an effective pyrene-based hydrogel. Pyr Phe OH can self-assemble into hydrogels in the range of pH=7.5-14.0, and also shows a very low gel concentration (0.037% (w/v)) in phosphate buffer .
|
- HY-W041983
-
- HY-W015230
-
- HY-W129585
-
- HY-W016948
-
- HY-W011342
-
- HY-W011913
-
- HY-W013517
-
- HY-W017406
-
- HY-W041984
-
- HY-W009006
-
- HY-W009124
-
- HY-W009211
-
- HY-W009258
-
- HY-134852
-
- HY-W009381
-
- HY-W097163
-
- HY-30231
-
- HY-W015231
-
- HY-W141779
-
- HY-W016731
-
- HY-W010590
-
- HY-W010721
-
- HY-W010782
-
- HY-W010788
-
- HY-W141946
-
- HY-W005144
-
- HY-W005815
-
- HY-W141985
-
- HY-W024554
-
- HY-W025807
-
- HY-W007108
-
- HY-W007399
-
- HY-W007706
-
- HY-W007750
-
- HY-W007941
-
- HY-W008016
-
- HY-W008072
-
- HY-W008196
-
- HY-W039449
-
- HY-W008386
-
- HY-W041857
-
- HY-W008800
-
- HY-W008869
-
- HY-W008872
-
- HY-W041997
-
- HY-W008942
-
- HY-W008958
-
- HY-W008986
-
- HY-W008981
-
- HY-W008926
-
- HY-W008389
-
- HY-W008273
-
- HY-W008256
-
- HY-W008075
-
- HY-W010962
-
- HY-W010964
-
- HY-W010965
-
- HY-W011026
-
- HY-W011064
-
- HY-W011074
-
- HY-W011089
-
- HY-W053531
-
- HY-W011199
-
- HY-W011255
-
- HY-W011488
-
- HY-W011553
-
- HY-W011606
-
- HY-W011892
-
- HY-W011903
-
- HY-W011977
-
- HY-W012064
-
- HY-W012075
-
- HY-W012104
-
- HY-W012379
-
- HY-W012451
-
- HY-W012709
-
- HY-W012713
-
- HY-W013083
-
- HY-W013118
-
- HY-W013143
-
- HY-W011278
-
- HY-W013185
-
- HY-W011126
-
- HY-W013293
-
- HY-W013297
-
- HY-W013198
-
- HY-W013155
-
- HY-W013659
-
- HY-W013678
-
- HY-W010976
-
- HY-W008464
-
- HY-W041990
-
- HY-W040024
-
- HY-W007942
-
- HY-W022447
-
- HY-W002436
-
- HY-W002326
-
- HY-W010943
-
- HY-W010862
-
- HY-W010830
-
- HY-W010794
-
- HY-W010734
-
- HY-W018650
-
- HY-77757
-
- HY-W141815
-
- HY-W009841
-
- HY-W015241
-
- HY-W009412
-
- HY-W009329
-
- HY-W009119
-
- HY-W007798
-
- HY-W008022
-
- HY-W142115
-
- HY-W014329
-
- HY-W008021
-
- HY-P5338
-
- HY-W008867
-
- HY-W008908
-
- HY-W011778
-
- HY-W141821
-
- HY-134578
-
|
Peptides
|
Others
|
H-Arg-Ser-Arg-OH is a short peptide. H-Arg-Ser-Arg-OH is a motif of di-leucine and RSRR, it can be used to design larger peptides and compound .
|
- HY-W111226
-
|
Amyloid-β
Amino Acid Derivatives
|
Cardiovascular Disease
|
Fmoc-His(3-Me)OH derives Histidine-associating compounds with biological activity. Fmoc-His(3-Me)OH, with Fmoc-citrulline-OH, Fmoc-His(1-Me)-OH together, forms tri-peptides and shows vasodilating effect with EC50s of 2.7-4.7 mM in 1.0 mM Phenylephrine (PE)-contracted aorta rings. Fmoc-His(3-Me)OH (resin) also makes Methyl-His-Gly-Lys (His(3-Me)-Gly-Lys), thus acts as an [Ca 2+]i inhibitor. Fmoc-His(3-Me)OH methylates NAHIS02, making it unable to block the Alzheimer's Aβ channel .
|
- HY-W013097
-
|
Amino Acid Derivatives
|
Others
|
Boc-Arg(di-Z)-OH can be used for the synthesis of amino acid. Boc-Arg(di-Z)-OH can be used for the research of inhibitors for processing proteinases. Boc-Arg(di-Z)-OH is coupled via the mixed anhydride (MA) with HGlu(OBzl)-Lys(Z)-Arg(Z,Z)-CH2Cl .
|
- HY-P4569
-
|
Peptides
|
Others
|
H-Ser-Pro-OH is a dipeptide containing serine and proline, which can serve as a substrate for prolinase I (PD I) and PD II. H-Ser-Pro-OH can also be used for the synthesis of polypeptide .
|
- HY-W102709
-
- HY-W010775
-
- HY-W011686
-
- HY-W048830
-
- HY-W010895
-
- HY-W008353
-
- HY-W008633
-
- HY-W011321
-
- HY-W013162
-
- HY-W010893
-
- HY-W009762
-
- HY-W017150
-
- HY-W011020
-
- HY-W008379
-
- HY-W041987
-
- HY-W141986
-
- HY-W010732
-
- HY-W048825
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-Ala-Ala-OH (3) is a self-assemble fluorenylmethoxycarbonyl-dipeptide, which is a smaller amphiphilic building blocks consists dipeptides linked to fluore nylmethoxycarbonyl (Fmoc). Fmoc-Ala-Ala-OH can be used as scaffold materials in 3D cell culture .
|
- HY-W008395
-
|
Amino Acid Derivatives
|
Others
|
Fmoc-D-Pra-OH is a Glycine (HY-Y0966) derivative . Fmoc-D-Pra-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-W141817
-
- HY-W141789
-
- HY-W009320
-
- HY-W004098
-
- HY-W009321
-
- HY-P3703
-
|
Peptides
|
Others
|
H-Val-Thr-Cys-Gly-OH is a cell attachment peptide. H-Val-Thr-Cys-Gly-OH is a bioactive molecule used for cell adhesion or other cell interactions .
|
- HY-W009260
-
- HY-W098060
-
- HY-23053
-
- HY-W015233
-
- HY-W015926
-
- HY-66024
-
- HY-W018366
-
- HY-W010714
-
- HY-W010888
-
- HY-W010924
-
- HY-W004083
-
- HY-W022444
-
- HY-W008156
-
- HY-W008359
-
- HY-W008495
-
- HY-W041986
-
- HY-W008866
-
- HY-W008887
-
- HY-Y1844
-
- HY-W043473
-
- HY-W008426
-
- HY-W050803
-
- HY-W051350
-
- HY-W062304
-
- HY-W011444
-
- HY-W012138
-
- HY-W012872
-
- HY-W013048
-
- HY-W013144
-
- HY-W011279
-
- HY-W013300
-
- HY-W053550
-
- HY-W013210
-
- HY-W051351
-
- HY-W042000
-
- HY-W041985
-
- HY-W013850
-
- HY-W014048
-
- HY-W022446
-
- HY-W022227
-
- HY-W010724
-
- HY-W010698
-
- HY-W140794
-
- HY-W009534
-
- HY-W016887
-
- HY-131095
-
- HY-W048332
-
- HY-77635
-
- HY-W016075
-
- HY-W005759
-
- HY-W008560
-
- HY-W050785
-
- HY-W011832
-
- HY-W013968
-
- HY-W018717
-
- HY-W010249
-
- HY-W013906
-
- HY-W008530
-
- HY-P4897
-
|
Peptides
|
Others
|
[Gly9-OH]-Atosiban is the analogue of Atosiban (HY-17572).
|
- HY-P5092
-
|
Peptides
|
Others
|
FA-Glu-Glu-OH is a dipeptide that can be used as an intermediate in peptide synthesis .
|
- HY-P3729
-
|
Peptides
|
Others
|
Ac-Lys-D-Ala-D-Ala-OH is an oligopeptide. Ac-Lys-D-Ala-D-Ala-OH can be used for the research of various biochemical .
|
- HY-19821
-
- HY-W142062
-
|
Amino Acid Derivatives
|
Others
|
cis-Fmoc-Pro(4-N3)-OH is a proline derivative . cis-Fmoc-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
- HY-W039756
-
NSC 334362
|
Amino Acid Derivatives
|
Others
|
Boc-Ala-Ala-OH (NSC 334362) is an Alanine derivative. Boc-Ala-Ala-OH is used in the preparation of anti-bacterial agent .
|
- HY-W016424
-
- HY-P4600
-
|
Peptides
|
Others
|
H-Ala-Arg-OH is an L-arginyl dipeptide that can be used as salt taste enhancer .
|
- HY-P10231
-
|
Carboxypeptidase
|
Others
|
Ac-Phe-Thiaphe-OH is a modified peptide, which is utilized as substrate for carboxypeptidase A (CPA) .
|
- HY-P4566
-
|
Peptides
|
Others
|
H-Pro-Val-OH is a deprotonation dipeptide containing proline, which can catalyze the Michael addition reaction of acetone to trans-β-nitrostyrene. H-Pro Val OH can also serve as a substrate for fibroblast enzymes and prolinase, and has potential applications in biochemical analysis .
|
- HY-P4560
-
|
Angiotensin-converting Enzyme (ACE)
|
Cardiovascular Disease
|
H-Pro-Phe-OH is a dipeptide containing proline and phenylalanine, which can serve as a substrate for prolinase. H-Pro-Phe-OH can also be used for polypeptide synthesis, where phenylalanine is an aromatic amino acid that can inhibit the activity of Angiotensin-converting enzyme (ACE, HY-P2983) .
|
- HY-W008326
-
- HY-W008999
-
- HY-W009023
-
- HY-W009403
-
- HY-W014919
-
- HY-W015177
-
- HY-W016031
-
- HY-W016555
-
- HY-W010825
-
- HY-W010894
-
- HY-W007615
-
- HY-W008269
-
- HY-W008486
-
- HY-W008527
-
- HY-W041866
-
- HY-W008995
-
- HY-W008971
-
- HY-W011154
-
- HY-W012487
-
- HY-W011178
-
- HY-W011021
-
- HY-W013714
-
- HY-W013874
-
- HY-W010931
-
- HY-W010871
-
- HY-W009402
-
- HY-W013735
-
- HY-P5469
-
|
Formyl Peptide Receptor (FPR)
|
Others
|
WRW4-OH is a biological active peptide. (This peptide inhibits binding of one of formyl peptide receptor-like 1 (FPRL1) agonists WKYMVm to its specific receptor. FPRL1 is an important classical chemoattractant receptor that is expressed in phagocytic cells in the peripheral blood and brain. Activation of FPRL1 is closely related to inflammatory responses in the host defense mechanism and neurodegenerative disorders.)
|
- HY-W001954
-
- HY-W010955
-
NSC 334018
|
Biochemical Assay Reagents
|
Others
|
Z-Phe-Leu-OH (NSC 334018) is a substrate for carboxypeptidase Y (CPY). Z-Phe-Leu-OH is incubated with recombinant CPY to determine peptidase activity .
|
- HY-P4552
-
|
Peptides
|
Others
|
Hippuryl-Phe-Arg-OH is the active site on the cell surface of Angiotensin I converting enzyme (ACE) .
|
- HY-P4716
-
|
Peptides
|
Inflammation/Immunology
|
Boc-D-Trp(For)-OH, containing the amino acid tryptophan, is synthesized by the ammonolysis of Boc-protected D-alanine, followed by cyclization to form a dipeptide with ninhydrin. Boc-D-Trp(For)-OH has pharmacological properties, including inhibition of growth hormone release, induction of sleep and antiinflammatory .
|
- HY-W008642
-
L-Leucyl-L-leucine
|
Peptides
|
Others
|
Leu-Leu-OH, a Leu derivative, is a dipeptide.
|
- HY-129028
-
- HY-P2614
-
|
Caspase
|
Others
|
Mca-DEVDAP-K(Dnp)-OH is a fluorogenic substrate for caspase-3 .
|
- HY-W141810
-
H-Phe(4-NH2)-OH hydrochloride
|
Endogenous Metabolite
|
Others
|
4-Amino-L-phenylalanine (H-Phe(4-NH2)-OH) hydrochloride is an endogenous metabolite.
|
- HY-W022281
-
- HY-W011033
-
- HY-W008529
-
- HY-W013740
-
- HY-W013745
-
- HY-W013769
-
- HY-W013749
-
- HY-W013152
-
- HY-W012907
-
- HY-W013779
-
- HY-P5040
-
- HY-W048829
-
|
Amino Acid Derivatives
|
Others
|
Boc-Phe-Gly-OH is a Boc-protected phenylalanyl glycine derivative, can be used for the synthesis of agents or other compounds .
|
- HY-W009912
-
|
Amino Acid Derivatives
|
Others
|
H-Tyr(Me)-OH is a synthetic amino acid, and can enter into protein in E. coli in response to an amber nonsense codon .
|
- HY-W010499
-
|
Biochemical Assay Reagents
|
Others
|
H-D-Homoser-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-W012908
-
|
Biochemical Assay Reagents
|
Others
|
H-DL-Pro-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-W048700
-
- HY-P3757
-
|
Peptides
|
Others
|
H-D-Tyr-Val-Gly-OH is a catalyst of the synthesis of phenylhydrazones .
|
- HY-126584
-
Val-val
|
Peptides
|
Others
|
H-VAL-VAL-OH is a dipeptide of the amino acid valine, an essential amino acid .
|
- HY-P2661
-
- HY-W008997
-
- HY-W009284
-
- HY-W016018
-
- HY-W010758
-
- HY-W010957
-
- HY-W142008
-
- HY-W042001
-
- HY-W042006
-
- HY-W008996
-
- HY-W008972
-
- HY-W011472
-
- HY-W012485
-
- HY-W012486
-
- HY-W010974
-
- HY-W141945
-
- HY-W010946
-
- HY-W010927
-
- HY-W010926
-
- HY-79294
-
- HY-W017617
-
- HY-W016339
-
- HY-W016028
-
- HY-W015279
-
- HY-W042007
-
- HY-W013726
-
- HY-W009686F
-
|
Peptides
|
Others
|
5-FAM-Pro-Leu-OH is a biological active peptide. (Used as MMP fluorescent reference standard)
|
- HY-Y1169
-
4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate; Fmoc-L-Asp(OtBu)-OH
|
Amino Acid Derivatives
|
Others
|
Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .
|
- HY-P4192
-
|
ADC Linker
|
Cancer
|
Fomc-Gly-Gly-Phe-Gly-OH (compound D5) can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit .
|
- HY-W042005
-
|
Amino Acid Derivatives
|
Others
|
H-D-Phe(3,4-DiCl)-OH is D-3,4-Dichlorophenylalanine, a amino acid derivative. H-D-Phe(3,4-DiCl)-OH shows protein synthesis activity .
|
- HY-W008308
-
- HY-W048674
-
Fmoc-O-acetyl-L-serine
|
Amino Acid Derivatives
|
Infection
|
Fmoc-Ser(Ac)-OH (Fmoc-O-acetyl-L-serine) is a Serine derivative. Fmoc-Ser(Ac)-OH can be used for the preparation of broad-spectrum coronavirus membrane fusion inhibitor .
|
- HY-P4632
-
|
Peptides
|
Others
|
H-γ-Glu-Leu-OH is a dipeptide consisting of γ-glutamic acid and leucine, terminated by a hydroxyl group .
|
- HY-129028A
-
|
Peptides
|
Others
|
H-Ala-Ala-Tyr-OH TFA can be synthesized mutant peptides .
|
- HY-W109513
-
|
Amino Acid Derivatives
|
Inflammation/Immunology
|
Boc-Lys(Z)-OH (DCHA) is a involves in synthesis thymosin β4, βg and β6 fragments, and increases E-rosette forming capacity in Lupus Nephritis model. Boc-Lys(Z)-OH (DCHA) involves in synthesis Boc-Lyz-OCH3 and acts as a reagent of peptidyl thrombin inhibitors production .
|
- HY-I1111
-
- HY-P3972
-
|
Peptides
|
Cancer
|
H-ILE-ARG-VAL-VAL-MET-OH is a pentapeptide from C7 with a domain that supports cell attachment. H-ILE-ARG-VAL-VAL-MET-OH is also the sequence fragment that binds to the thrombospondin-1 (TS1) receptor .
|
- HY-W011002
-
- HY-W022404
-
- HY-W010880
-
- HY-W016032
-
- HY-W009215
-
L-Met-L-Ala-L-Ser
|
Peptides
|
Others
|
H-Met-Ala-Ser-OH (L-Met-L-Ala-L-Ser) is a tripeptide. H-Met-Ala-Ser-OH can act as a formyl receptor .
|
- HY-P2616
-
- HY-P2396
-
- HY-P2400
-
- HY-P2405
-
- HY-P2390
-
- HY-P2393
-
- HY-P2398
-
- HY-P2409
-
- HY-P2410
-
- HY-P2386
-
- HY-P2385
-
- HY-P1529
-
- HY-W052227
-
- HY-W008432
-
- HY-W010850
-
- HY-W013824
-
- HY-W011258
-
L-Tyrosyl-L-phenylalanine
|
Xanthine Oxidase
Angiotensin-converting Enzyme (ACE)
|
Inflammation/Immunology
Cancer
|
H-Tyr-Phe-OH (L-Tyrosyl-L-phenylalanine) is an orally active inhibitor of Angiotensin converting enzyme (ACE), with an inhibiton rate of 48% at 50 μM. H-Tyr-Phe-OH can be used as an biomarker for differentiating benign thyroid nodules (BTN) from thyroid cancer (TC). H-Tyr-Phe-OH exhibits xanthine oxidase inhibition (uric acid lowering) activity and serves as regulator in IL-8 production in neutrophil-like cells .
|
- HY-W042008
-
- HY-P2402
-
- HY-111922
-
Glycyl-glycyl-L-proline
|
Peptides
|
Others
|
H-Gly-Gly-Pro-OH is a peptide with 3 amino acid.
|
- HY-114161
-
- HY-W006069
-
|
Peptides
|
Others
|
H-Phe(3,5-DiF)-OH is a difluorophenylalanines in the L-configuration [L-(F2)Phe]. H-Phe(3,5-DiF)-OH can be incorporated into the thrombin receptor-tethered ligand peptide SFLLRNP to identify the phenyl hydrogens of the Phe-2 residue involved in the CH/π receptor interaction .
|
- HY-42709
-
- HY-W013781
-
|
Peptides
|
Others
|
Boc-Glu(OBzl)-OH (Compound 9) is a glutamic acid derivative commonly used in Boc SPPS. Glutamic acid residues increase the hydrophilicity of the polypeptide and play an important structural and receptor binding role .
|
- HY-P3971
-
|
TGF-beta/Smad
|
Inflammation/Immunology
|
H-Leu-Ser-Lys-Leu-OH (LSYL) is a latency-associated peptide at the amino terminus of LAP, with inhibitory effect on TGF-β1 activation. H-Leu-Ser-Lys-Leu-OH, binding with KRFK (HY-P3970), can block the signal transduction of TGF-β1, and prevent the progression of hepatic damage and fibrosis .
|
- HY-P2389
-
- HY-P2395
-
- HY-P2397
-
- HY-P2399
-
- HY-P2401
-
- HY-P2403
-
- HY-P2404
-
- HY-P2407
-
- HY-P2408
-
- HY-P2384
-
- HY-P2388
-
- HY-P2411
-
- HY-P2391
-
- HY-P2412
-
- HY-P2387
-
- HY-W022255
-
D-Fmoc-glutamic acid
|
Amino Acid Derivatives
|
Others
|
Fmoc-D-Glu-OH (D-Fmoc-glutamic acid) is a derivative of glutamate, can be used to prepare supramolecular hydrogels .
|
- HY-P2616A
-
- HY-114424
-
- HY-114424A
-
- HY-113089A
-
H-Glu(H-Lys-OH)-OH TFA; γ-Glu-ε-Lys TFA
|
Endogenous Metabolite
|
Metabolic Disease
|
Epsilon-(gamma-glutamyl)-lysine (H-Glu(H-Lys-OH)-OH) TFA is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration .
|
- HY-P2608
-
|
Fluorescent Dye
|
Others
|
DNP-Pro-Leu-Ala-Leu-Trp-Ala-Arg-OH is the substrate for matrix metalloproteinase MMP-1, with a Km of 26.61 μM. DNP-Pro-Leu-Ala-Leu-Trp-Ala-Arg-OH is utilized as fluorescence probe for detecting protein activity .
|
- HY-W010591
-
- HY-P2394
-
- HY-P2718
-
- HY-114161A
-
- HY-P1449
-
|
ADC Linker
|
Cancer
|
Boc-Gly-Gly-Phe-Gly-OH, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).
|
- HY-P2392
-
- HY-P3786
-
|
PKA
PKC
|
Cancer
|
H-Arg-Gly-Tyr-Ala-Leu-Gly-OH is a competitive and CAMP dependent protein kinase inhibitor .
|
- HY-P1853
-
- HY-P2536
-
- HY-75332
-
D-Cbz phenylglycine
|
Amino Acid Derivatives
|
Others
|
Z-D-Phg-OH (D-Cbz phenylglycine) is a N-blocked amino acids with Kd values of 390 μM and 323 μM for tBuCQN and tBuCQD, respectively .
|
- HY-15400
-
- HY-P1449A
-
|
ADC Linker
|
Cancer
|
Boc-Gly-Gly-Phe-Gly-OH TFA, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).
|
- HY-P4539
-
|
Peptides
|
Others
|
H-Thr-Asp-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4643
-
|
Peptides
|
Others
|
H-Trp-Met-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4652
-
|
Peptides
|
Others
|
H-Tyr-Ile-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4639
-
|
Peptides
|
Others
|
H-Trp-Asn-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4626
-
|
Peptides
|
Others
|
H-Thr-Phe-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4619
-
|
Peptides
|
Others
|
H-Thr-Glu-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4630
-
|
Peptides
|
Others
|
H-Thr-Pro-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4635
-
|
Peptides
|
Others
|
H-Trp-Arg-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4661
-
|
Peptides
|
Others
|
H-Val-Gln-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4533
-
|
Peptides
|
Others
|
H-Thr-Ala-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4537
-
|
Peptides
|
Others
|
H-Thr-Arg-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P5008
-
|
Peptides
|
Others
|
Cbz-Asn-Gly-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P5042
-
|
Peptides
|
Others
|
Cbz-Tyr-Ala-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P5091
-
|
Peptides
|
Others
|
FA-Phe-Ala-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4549
-
- HY-W005720
-
- HY-P4022
-
- HY-P4561
-
|
Cathepsin
|
Others
|
H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH is a water-soluble polypeptide that can serve as a substrate for cathepsin D, pepsin and pepsinogen. H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH has potential applications in biochemical analysis .
|
- HY-P3413
-
- HY-P4557
-
|
Peptides
|
Others
|
H-Phe-Leu-Glu-Glu-Leu-OH is a synthetic pentapeptide, which can be used as the substrate of vitamin K dependent carboxylase, and a glutamyl residue in the generated product is carboxylated .
|
- HY-41912B
-
Boc-D-Nle-OH; N-BOC-D-norleucine
|
Amino Acid Derivatives
|
Others
|
Boc-D-norleucine (Boc-D-Nle-OH) is a leucine derivative that can be used for peptide synthesis .
|
- HY-P4850
-
|
Peptides
|
Others
|
Ac-Pro-Leu-Gly-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-W012000
-
Boc-N-Me-Ile-OH
|
Amino Acid Derivatives
|
Others
|
Boc-N-methyl-L-isoleucine (Boc-N-Me-Ile-OH) is a peptide products and can be used as a precursor in organic synthesis and pharmaceuticals .
|
- HY-P4602
-
|
Peptides
|
Others
|
(H-Cys-Tyr-OH)2 is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-W012159
-
H-MET-SER-OH
|
Angiotensin-converting Enzyme (ACE)
|
Cardiovascular Disease
|
Methionylserine (H-MET-SER-OH) is a methionine- and serine-containing dipeptide. Methionylserine binds to and translocation via intestinal di/tri-peptide transporter 1 (hPEPT1) with a Km value of 0.2 mM. Methionylserine inhibits ACE enzyme activity. Methionylserine can be used in the research of hypension .
|
- HY-22062
-
- HY-P0073
-
Met-Enkephalin; Methionine enkephalin; Metenkefalin
|
Opioid Receptor
|
Neurological Disease
Cancer
|
Tyr-Gly-Gly-Phe-Met-OH regulates human immune function and inhibits tumor growth via binding to the opioid receptor.
|
- HY-76317
-
N-Cbz-DL-proline; DL-Cbz-Proline
|
Amino Acid Derivatives
|
Others
|
Z-DL-Pro-OH (N-Cbz-DL-proline) is a proline derivative, can be used for the synthesis of agents or other compounds .
|
- HY-A0299
-
Tripeptide 29
|
Peptides
|
Others
|
HGly-Pro-Hyp-OH (Tripeptide 29) is an orally active bioactive peptide against UVB-induced skin aging and has been reported used as a cosmetic ingredient [1]
|
- HY-41912
-
N-[(1,1-Dimethylethoxy)carbonyl]-L-norleucine; BOC-L-norleucine; BOC-norleucine; N-(tert-Butoxycarbonyl)norleucine
|
Amino Acid Derivatives
|
Others
|
Boc-Nle-OH is a leucine derivative .
|
- HY-P5326
-
|
Peptides
|
Others
|
EDANS-CO-CH2-CH2-CO-ALERMFLSFP-Dap(DABCYL)OH is a biological active peptide. (Plasmepsin I substrate)
|
- HY-P1200
-
|
Src
|
Cancer
|
Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH (compound 1) is a high-affinity pentapeptide to bind to the src SH2 domain (IC50≈1 µM). Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH is an inhibitor for src SH3-SH2:phosphoprotein interactions .
|
- HY-P10038
-
Myr-FEEERA-OH
|
Integrin
|
Infection
|
mP6 (Myr-FEEERA-OH) is a myristoylated peptide. mP6 inhibits the interaction of Gα13 with integrin β3 without disrupting talin-dependent integrin function. mP6 can block the GTP usage of Rac1, Rap1, and Rab7, effectively inhibiting the infection of CHO-A24 cells .
|
- HY-W002299
-
Boc-D-Leu-OH hydrate
|
Amino Acid Derivatives
|
Neurological Disease
|
Boc-D-Leucine monohydrate (Boc-D-Leu-OH hydrate) is an N-Boc-protected form of D-Leucine (L330150). D-Leucine is an unnatural isomer of L-Leucine (L330110) that acts as an auto-inhibitor of lactic streptococci. D-Leucine shows potent anti-seizure effect .
|
- HY-P3760
-
|
Peptides
|
Others
|
H-Pro-Phe-Thr-Arg-Asn-Tyr-Tyr-Val-Arg-Ala-Val-Leu-His-Leu-OH is an peptide. H-Pro-Phe-Thr-Arg-Asn-Tyr-Tyr-Val-Arg-Ala-Val-Leu-His-Leu-OH can be used for the research of various biochemical studies .
|
- HY-P4597
-
|
Peptides
|
Others
|
(H-Cys-Phe-OH)2 (disulfide bond) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P5012
-
NSC 186902
|
Peptides
|
Others
|
Cbz-Glu-Gly-OH (NSC 186902) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P5024
-
NSC 333754
|
Peptides
|
Others
|
Cbz-Ile-Pro-OH (NSC 333754) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P1200A
-
|
Src
|
Cancer
|
Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA (compound 1) is a high-affinity pentapeptide to bind to the src SH2 domain (IC50≈1 µM). Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA is an inhibitor for src SH3-SH2:phosphoprotein interactions .
|
- HY-W015236
-
Triglycine
|
Biochemical Assay Reagents
|
Others
|
H-Gly-Gly-Gly-OH, also known as Triglycine, is a tripeptide composed of glycine, glycine and glycine, which are linked by peptide bonds. Often used as a model compound in the study of protein structure and function. Glycylglycylglycine also acts as a neurotransmitter in the central nervous system and has been shown to have antioxidant properties. Furthermore, it may have potential research roles in various diseases such as cancer, diabetes and neurodegenerative diseases.
|
- HY-13718
-
H-Glu-Trp-OH; L-Glutamyl-L-tryptophan
|
VEGFR
HCV
Endogenous Metabolite
|
Infection
Cardiovascular Disease
Inflammation/Immunology
Cancer
|
Oglufanide (H-Glu-Trp-OH) is a dipeptide immunomodulator isolated from calf thymus. Oglufanide inhibits vascular endothelial growth factor (VEGF). Oglufanide can stimulate the immune response to hepatitic C virus (HCV) and intracellular bacterial infections. Oglufanide shows antitumor and anti-angiogenesis activities .
|
- HY-P5000
-
H-Asp-Tyr-OH
|
Peptides
|
Others
|
Cholecystokinin Octapeptide (1-2) (desulfated) (H-Asp-Tyr-OH) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P1591
-
- HY-P1591A
-
- HY-Y1250
-
Fmoc glycine; N-(9-Fluorenylmethoxycarbonyl)glycine; N-Fluorenylmethoxycarbonylglycine; NPC 14692; NSC 334288; [[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]acetic acid
|
Amino Acid Derivatives
|
Others
|
Fmoc-Gly-OH (Fmoc glycine) is a Fmoc-protected glycine derivative, can be used for the synthesis of compounds .
|
- HY-P2844
-
|
DNA/RNA Synthesis
|
Metabolic Disease
|
Polynucleotide Kinase is a DNA repair enzyme. Polynucleotide Kinase possesses both a 5’-kinase activity that catalyzes the transfer of phosphate from ATP to a 5’-hydroxyl (OH) terminus and also a 3’-phosphatase activity that converts 3’-phosphate termini to 3’-OH termini .
|
- HY-W714002
-
|
HIV
Bacterial
|
Infection
|
Feglymycin is a HIV replication inhibitor. Feglymycin is also an antibiotic peptide that has antibacterial activity (MIC: 32-64 μg/mL for Staphylococcus aureus) .
|
- HY-P4239
-
|
Peptides
|
Others
|
Ala-Ala-Ala-Ala-Ala-Ala is a hexapeptide composed of six alanine amino acid residues .
|
- HY-P10299
-
|
Peptides
|
Others
|
Calcitonin, porcine inhibits 1,25 (OH)2D3-stimulated porcine osteoclast differentiation. Calcitonin is a polypeptide hormone that can lower serum calcium by decreasing calcium reabsorption in the kidney and inhibiting osteoclastic bone resorption. Calcitonin, porcine can be used for research of hypercalcemia .
|
- HY-W010719
-
- HY-113736
-
|
Amino Acid Derivatives
|
Others
|
Glycyllysine is a polypeptide that can be used in the synthesis of antibodies and amino acid type gemini surfactants. Glycyllysine has potential applications in modifying plasmid/gemini/lipid (P/G/L) nanoparticles transport carriers .
|
- HY-P4315
-
|
Peptides
|
Others
|
Histidylmethionine is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4666
-
|
Peptides
|
Others
|
Valylhistidine is a dipeptide consisting of valine and histidine (Val-His). Valylhistidine forms a dipeptide complex with Cu(II) that mimics superoxide dismutase, but lacks activity .
|
- HY-P4650
-
|
Peptides
|
Cardiovascular Disease
|
Tyrosylhistidine is a dipeptide consisting of tyrosine and histidine (Tyr-His). Tyrosylhistidine is an orally active antihypertensive peptide. Tyrosylhistidine reduces blood pressure in mice in a model of spontaneous hypertension .
|
- HY-P4662
-
|
Peptides
|
Others
|
Valylglutamic acid is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4497
-
|
ERK
|
Cancer
|
Prolylserine, a dipeptide, is an inhibitor of melanogenesis production in Mel-Ab cells. Prolylserine decreases expression of microphthalmia-associated transcription factor (MITF) and tyrosinase, induces phorphosylation of ERK, but not cAMP response element binding protein (CREB) .
|
- HY-P4511
-
|
Peptides
|
Infection
|
Serylleucine is a dipeptide. Serylleucine's core 1 o-glycosylated peptide (SLC1G) can be detected in urine as a metabolite and is a biomarker in TB studies .
|
- HY-P4263
-
|
Peptides
|
Others
|
Glycylglycylalanine is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4230
-
|
Peptides
|
Others
|
Glycylalanylglycine is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4236
-
|
Peptides
|
Others
|
Gly-d-Phe is an affinity ligand for Thermolysin (HY-P1748) . Gly-d-Phe can be used as the substrate of membrane dipeptidase (MDP) .
|
- HY-P4269
-
|
Peptides
|
Cardiovascular Disease
|
Glycylglycylcysteine is a Thrombin Activatable Fibrinolysis Inhibitor (TAFI) inhibitor with a Ki of 0.99 μM and a IC50 of 9.4 μM in TAFI substrate assays. TAFI is a basic carboxypeptidase that functions as a fibrinolysis inhibitor through the cleavage of C-terminal lysine on partially degraded fibrin .
|
- HY-P4283
-
|
Peptides
|
Others
|
Glycylhistidylglycine is composed of two glycines and one histidine, which can detect and remove the concentration of Cu2+ ions in wastewater by forming a tripeptide complex with copper and nickel ions.
|
- HY-P4663
-
NSC 350591
|
Peptides
|
Cancer
|
Val-Gly-Ser-Glu (NSC 350591) is an ECF-A tetrapeptide. Val-Gly-Ser-Glu dose-dependently increases the number of human eosinophils, but not neutrophils, rosetting with complement-coated sheep erythrocytes (EAC3b) .
|
- HY-P0018
-
Pepstatin
Maximum Cited Publications
26 Publications Verification
Pepstatin A
|
HIV Protease
Autophagy
|
Infection
Inflammation/Immunology
|
Pepstatin (Pepstatin A) is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin also inhibits HIV protease .
|
- HY-P0018A
-
Pepstatin A Trifluoroacetate
|
HIV Protease
Autophagy
|
Infection
Inflammation/Immunology
|
Pepstatin (Pepstatin A) Trifluoroacetate is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin Trifluoroacetate also inhibits HIV protease .
|
- HY-P0095
-
|
Angiotensin-converting Enzyme (ACE)
|
Others
|
Acetyl tetrapeptide-5 inhibits glycosylation and ACE-1 activity. Acetyl tetrapeptide-5 reduces edema and relieves vascular pressure by improving the vascular system and strengthening the skin under the eyes. Acetyl tetrapeptide-5 can be used in the research of Antioxidant, anti-aging skin care .
|
- HY-P4508
-
|
Peptides
|
Others
|
SIGSLAK has the active site of E. coli penicillin-binding protein 1b .
|
- HY-P4510
-
|
Peptides
|
Others
|
SLSLSPG can be obtained from the C-end of the heavy chain of human Igγ-1. SLSLSPG is a common variant in IgG .
|
- HY-P0232
-
- HY-113089
-
H-Glu(H-Lys-OH)-OH; γ-Glu-ε-Lys
|
Endogenous Metabolite
|
Metabolic Disease
|
Epsilon-(gamma-glutamyl)-lysine is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration .
|
- HY-W141910
-
- HY-P4083
-
|
Peptides
|
Others
|
(Arg)9,TAMRA-labeled is a TAMRA-labeled cell permeable peptide. (Arg)9 is a cell-permeable peptide used for drug delivery .
|
- HY-P4628
-
LRH-1 peptide
|
Peptides
|
Inflammation/Immunology
|
TPNQRQNVC is a nonapeptide and is the epitope of HLA-B0702. TPNQRQNVC induces a CD8+ T cell immune response .
|
- HY-P1116
-
|
Bacterial
|
Infection
Inflammation/Immunology
|
PBP10 is a cell permeable and selective gelsolin-derived peptide inhibitor of formyl peptide receptor 2 (FPR2) over FPR1 . PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity against gram-positive and gram-negative bacteria and limits microbial-induced inflammatory effects .
|
- HY-P1116A
-
|
Bacterial
|
Infection
Inflammation/Immunology
|
PBP10 is a cell permeable and selective gelsolin-derived peptide inhibitor of formyl peptide receptor 2 (FPR2) over FPR1 . PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity against gram-positive and gram-negative bacteria and limits microbial-induced inflammatory effects .
|
- HY-P4105
-
- HY-P10131
-
|
FAP
|
Cancer
|
3BP-3940 is a highly potent fibroblast activation protein (FAP)-targeting peptide for theranostics. 3BP-3940 is often coupled with radionuclides for tumor diagnosis and treatment .
|
- HY-P4325
-
|
Peptides
|
Others
|
Hirudin (55-65) (sulfated) is a fragment of Hirudin with anticoagulant effects. Hirudin is a thrombin inhibitor with blood anticoagulant property.
|
- HY-P4358
-
|
Peptides
|
Others
|
LAAVSDLNPNAPR is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-105183
-
|
Peptides
|
Others
|
PD 145065 is a highly potent but non-selective endothelin receptor antagonist with an IC50 value of 4 nM for the ETA receptor for rabbit renal artery vascular smooth muscle cells .
|
- HY-P4703
-
|
Peptides
|
Others
|
Hydrin 1′ is found in the neurohypophysis of Xenopus. Hydrin 1′ possesses a considerable steroid-releasing activity in Xenopus adrenal gland in vitro .
|
- HY-P4104
-
|
Peptides
|
Others
|
pVEC (Cadherin-5) is a cell-penetrating 18-amino acid-long peptide derived from the murine sequence of the cell adhesion molecule vascular endothelial cadherin. pVEC (Cadherin-5) is efficiently and rapidly taken up into cells, it can be used as a carrier peptide .
|
- HY-P4351
-
|
HIV
|
Others
|
HIV-1 gag Protein p24 (194-210) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P4352
-
|
HIV
|
Others
|
HIV-2 Peptide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P0082F
-
|
Peptides
|
Others
|
Glucagon (1-29), FAM-labeled is a biological active peptide. (FAM labeled HY-P0082)
|
- HY-P5057
-
|
Peptides
|
Others
|
5-FAM-LL-37 is afluorescent labeled LL-37, human (HY-P1222).
|
- HY-P5354
-
|
Peptides
|
Others
|
FRETS-VWF73 is a biological active peptide. (FRETS-VWF73 is a very powerful Fluorescence-Quenching Substrate for the VWF cleaving protease ADAMTS-13. It is commonly used as a useful tool for the rapid measurement of ADAMTS-13 activity in plasma and is a predictive marker for various thrombotic diseases like TPP. Our new substrate FRETS-VWF73 can be easily used with a 96-well format in commercial plate readers.)
|
- HY-W007052
-
- HY-P1610
-
|
Peptides
|
Cancer
|
Asudemotide (S-588410) is a peptide of human DEP domain-containing protein 1A. Asudemotide is an immunostimulant. Asudemotide has a sequence of H-Glu-Tyr-Tyr-Glu-Leu-Phe-Val-Asn-Ile-OH. Asudemotide induces a tumor immune response in esophageal cancer. .
|
- HY-115379
-
|
Peptides
|
Cancer
|
Latromotide is a synthetic peptide with antineoplastic activity. It consists of 10 amino acids corresponding to amino acid residues 66-75 of the human kinesin-like protein KIF20A. Latromotide has a sequence of H-Lys-Val-Tyr-Leu-Arg-Val-Arg-Pro Leu-Leu-OH .
|
- HY-W072732
-
Fmoc-N(Bn)-L-Ala-OH
|
Peptides
|
Others
|
N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N-benzyl-L-alanine is an alanine derivative .
|
- HY-Z0615
-
Boc-L-Asp(OBn)-OH
|
Amino Acid Derivatives
|
Others
|
(2S)-4-(Benzyloxy)-2-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid is an aspartic acid derivative .
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-W027951
-
-
-
- HY-W004066
-
-
-
- HY-W012340
-
-
-
- HY-W013293
-
-
-
- HY-W016647
-
-
-
- HY-W008385
-
-
-
- HY-W007035
-
-
-
- HY-W092109
-
-
-
- HY-W016887
-
-
-
- HY-W008452
-
-
-
- HY-W009338
-
-
-
- HY-126488
-
-
-
- HY-121711
-
-
-
- HY-126487
-
-
-
- HY-W008315
-
-
-
- HY-W008642
-
-
-
- HY-W007970
-
-
-
- HY-W141810
-
-
-
- HY-W010589
-
-
-
- HY-W011982
-
-
-
- HY-126487A
-
-
-
- HY-66007
-
-
-
- HY-W012874
-
-
-
- HY-W009602
-
-
-
- HY-W012479
-
-
-
- HY-N12513
-
-
-
- HY-W014130A
-
-
-
- HY-W012734
-
-
-
- HY-W014423
-
-
-
- HY-113089A
-
-
-
- HY-W014130
-
-
-
- HY-107378
-
-
-
- HY-W016781
-
-
-
- HY-W010104
-
-
-
- HY-113003
-
-
-
- HY-W010378
-
-
-
- HY-113482
-
-
-
- HY-13718
-
-
-
- HY-N10219
-
-
-
- HY-107233
-
-
-
- HY-W008129
-
-
-
- HY-P0018
-
Pepstatin
Maximum Cited Publications
26 Publications Verification
Pepstatin A
|
Structural Classification
Natural Products
Microorganisms
Classification of Application Fields
Source classification
Disease Research Fields
Cancer
|
HIV Protease
Autophagy
|
Pepstatin (Pepstatin A) is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin also inhibits HIV protease .
|
-
-
- HY-P0018A
-
Pepstatin A Trifluoroacetate
|
Infection
Structural Classification
Natural Products
Microorganisms
Classification of Application Fields
Source classification
Disease Research Fields
|
HIV Protease
Autophagy
|
Pepstatin (Pepstatin A) Trifluoroacetate is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin Trifluoroacetate also inhibits HIV protease .
|
-
-
- HY-113089
-
-
-
- HY-135212
-
-
-
- HY-N2442
-
-
-
- HY-W040088
-
-
-
- HY-W012161
-
-
-
- HY-N0501
-
-
-
- HY-N7404
-
-
- HY-113479
-
-
- HY-N3810
-
|
Structural Classification
Terpenoids
Source classification
Pteridaceae
Diterpenoids
Plants
Pteris semipinnata L. Sp.
|
Tyrosinase
|
ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid is an anti-melanin synthesis tyrosinase inhibitor, which can be isolated from Pteris fern. ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid regulates the melanogenesis transcription factor microphthalmia-associated transcription factor (MITF). The 11α-OH, 15-oxo and 16-en moieties of ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid are key fragments that inhibit melanin synthesis. The 19-COOH moiety has been implicated in the inhibition of cytotoxicity associated with 11α-OH KA and related compounds .
|
-
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-W004066S
-
|
Ac-Ala-OH-d3 is the deuterium labeled Ac-Ala-OH. Ac-Ala-OH is an endogenous metabolite.
|
-
-
- HY-117580S
-
|
16α-Hydroxyprednisolone-d3 is the deuterium labeled 16α-Hydroxyprednisolone. 16α-Hydroxyprednisolone is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid budesonide via cytochrome P450 3A (CYP3A) enzymes[1][2].
|
-
-
- HY-W004066S1
-
|
Ac-Ala-OH-d4 is the deuterium labeled Ac-Ala-OH. Ac-Ala-OH is an endogenous metabolite.
|
-
-
- HY-79131S5
-
|
Fmoc-Phe-OH- 13C is the 13C labeled Fmoc-Phe-OH[1]. Fmoc-Phe-OH is a phenylalanine derivative[2].
|
-
-
- HY-41121S6
-
|
Boc-L-Ala-OH-d is the deuterium labeled Boc-L-Ala-OH[1].
|
-
-
- HY-79131S4
-
|
Fmoc-Phe-OH-d8 is the deuterium labeled Fmoc-Phe-OH.
|
-
-
- HY-W007720S
-
|
Fmoc-Ser-OH-d3 is the deuterium labeled Fmoc-Ser-OH.
|
-
-
- HY-W007720S1
-
|
Fmoc-Ser-OH- 15N is the 15N labeled Fmoc-Ser-OH.
|
-
-
- HY-W008371S2
-
|
Fmoc-Met-OH-d3 is the deuterium labeled Fmoc-Met-OH.
|
-
-
- HY-W009204S8
-
|
Fmoc-Ala-OH-d is the deuterium labeled Fmoc-Ala-OH[1].
|
-
-
- HY-W013780S3
-
|
Fmoc-Pro-OH-d3 is the deuterium labeled Fmoc-Pro-OH.
|
-
-
- HY-I1111S
-
|
Fmoc-L-Val-OH-d8 is a deuterium labeled Fmoc-L-Val-OH. Fmoc-L-Val-OH is a kind of protect amino acids[1].
|
-
-
- HY-W009204S
-
|
Fmoc-Ala-OH- 15N is the 15N labeled Fmoc-Ala-OH[1].
|
-
-
- HY-W008371S
-
|
Fmoc-Met-OH- 15N is the 15N labeled Fmoc-Met-OH[1].
|
-
-
- HY-Y1250S
-
|
Fmoc-Gly-OH- 15N is the 15N labeled Fmoc-Gly-OH[1].
|
-
-
- HY-79131S2
-
|
Fmoc-Phe-OH-d5 is the deuterium labeled Fmoc-Phe-OH[1].
|
-
-
- HY-W009204S6
-
|
Fmoc-Ala-OH-d4 is the deuterium labeled Fmoc-Ala-OH[1].
|
-
-
- HY-W008385S
-
|
H-HoArg-OH-d4 is a deuterium labeled H-HoArg-OH (HY-W008385). H-HoArg-OH, a homologue arginine, is a strong inhibitor of human bone and liver alkaline phosphatase.
|
-
-
- HY-Y1250S3
-
|
Fmoc-Gly-OH- 13C is a 13C-labeled Fmoc-Phe-OH[1].
|
-
-
- HY-W007941S1
-
|
Fmoc-Ser(tBu)-OH- 15N is the 15N labeled Fmoc-Ser(tBu)-OH[1]. Fmoc-Ser(tBu)-OH is a serine derivative[2].
|
-
-
- HY-41121S4
-
|
Boc-L-Ala-OH- 15N is the 15N labeled Boc-L-Ala-OH.
|
-
-
- HY-W007798S1
-
|
Fmoc-Cys(Trt)-OH-d2 is the deuterium labeled Fmoc-Cys(Trt)-OH. Fmoc-Cys(Trt)-OH is an N-terminal protected cysteine derivative[1].
|
-
-
- HY-W010589S
-
|
H-Abu-OH-d3 is the deuterium labeled H-Abu-OH. H-Abu-OH, one of the three isomers of aminobutyric acid, is elevated in the plasma of children with with Reye's syndrome, tyrosinemia, homocystinuria, nonketotic hyperglycinemia, and ornithine transcarbamylase deficiency.
|
-
-
- HY-W010589S1
-
|
H-Abu-OH-d2 is the deuterium labeled H-Abu-OH. H-Abu-OH, one of the three isomers of aminobutyric acid, is elevated in the plasma of children with with Reye's syndrome, tyrosinemia, homocystinuria, nonketotic hyperglycinemia, and ornithine transcarbamylase deficiency.
|
-
-
- HY-W010589S2
-
|
H-Abu-OH-d6 is the deuterium labeled H-Abu-OH. H-Abu-OH, one of the three isomers of aminobutyric acid, is elevated in the plasma of children with with Reye's syndrome, tyrosinemia, homocystinuria, nonketotic hyperglycinemia, and ornithine transcarbamylase deficiency.
|
-
-
- HY-41121S3
-
|
Boc-L-Ala-OH-d3 is the deuterium labeled Boc-L-Ala-OH[1].
|
-
-
- HY-41121S5
-
|
Boc-L-Ala-OH-d4 is the deuterium labeled Boc-L-Ala-OH[1].
|
-
-
- HY-W007750S
-
|
H-Lys(Z)-OH-d3 is the deuterium labeled H-Lys(Z)-OH.
|
-
-
- HY-W008072S
-
|
Fmoc-D-Ala-OH-d3 is the deuterium labeled Fmoc-D-Ala-OH.
|
-
-
- HY-W011026S
-
|
Fmoc-D-Phe-OH-d5 is the deuterium labeled Fmoc-D-Phe-OH.
|
-
-
- HY-W011026S1
-
|
Fmoc-D-Phe-OH-d8 is the deuterium labeled Fmoc-D-Phe-OH.
|
-
-
- HY-W012713S
-
|
Ac-D-Ala-OH-d4 is the deuterium labeled Ac-D-Ala-OH.
|
-
-
- HY-W012908S2
-
|
H-DL-Pro-OH-d3 is the deuterium labeled H-DL-Pro-OH.
|
-
-
- HY-W015241S
-
|
Ac-D-Glu-OH-d5 is the deuterium labeled Ac-D-Glu-OH.
|
-
-
- HY-W009204S3
-
|
Fmoc-Ala-OH-3- 13C is the 13C labeled Fmoc-Ala-OH[1].
|
-
-
- HY-W009204S2
-
|
Fmoc-Ala-OH-1- 13C is the 13C labeled Fmoc-Ala-OH[1].
|
-
-
- HY-41121S
-
|
Boc-Ala-OH-1- 13C is the 13C labeled Boc-Ala-OH[1].
|
-
-
- HY-W010389S2
-
|
Ac-DL-Ala-OH-d4 is the deuterium labeled Ac-DL-Ala-OH[1].
|
-
-
- HY-W010590S1
-
|
H-DL-Abu-OH-d6 is the deuterium labeled H-DL-Abu-OH[1].
|
-
-
- HY-79131S
-
|
Fmoc-Phe-OH- 13C6 is a 13C-labeled Fmoc-Ala-OH[1].
|
-
-
- HY-Y0134S
-
|
Fmoc-Glu(OtBu)-OH- 15N is a 15N-labeled Fmoc-L-Val-OH[1].
|
-
-
- HY-Y1250S5
-
|
Fmoc-Gly-OH- 13C2 is a 13C-labeled Fmoc-Gly-OH (HY-Y1250). Fmoc-Gly-OH (Fmoc glycine) is a Fmoc-protected glycine derivative, can be used for the synthesis of compounds .
|
-
-
- HY-W010712S1
-
|
Fmoc-His(Trt)-OH- 15N3 is the 15N labeled Fmoc-His(Trt)-OH[1]. Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation[2].
|
-
-
- HY-I1111S3
-
|
Fmoc-L-Val-OH- 13C5 is a 13C-labeled Fmoc-Gly-OH[1].
|
-
-
- HY-79128S
-
|
Fmoc-L-Lys (Boc)-OH- 15N2 is a 15N-labeled Fmoc-L-Lys (Boc)-OH (HY-79128). Fmoc-L-Lys (Boc)-OH is a lysine derivative .
|
-
-
- HY-109502S
-
|
10-OH-NBP-d4 is deuterium labeled 10-OH-NBP. 10-OH-NBP is a Butylphthalide (3-n-Butylphthalide; NBP; HY-B0647) hydroxylated metabolite and can penetrates the blood-brain barrier (BBB). Butylphthalide exerts neuroprotective effects and has potential for cerebral ischemia research[1].
|
-
-
- HY-41121S2
-
|
Boc-L-Ala-OH-2- 13C is a 13C-labeled H-Lys-OH.2HCl[1].
|
-
-
- HY-Y1250S2
-
|
Fmoc-Gly-OH-2,2-d2 is the deuterium labeled Fmoc-Gly-OH-2,2[1].
|
-
-
- HY-Y1636S1
-
|
L-Arginine-N-FMOC PBF-OH- 13C6 is the 13C labeled Fmoc-Arg(Pbf)-OH[1]. Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis)[2].
|
-
-
- HY-W008452S
-
|
H-Tyr(3-I)-OH- 13C6 is the 13C-labeled H-Tyr(3-I)-OH. H-Tyr(3-I)-OH is a potent and effective tyrosine hydroxylase inhibitor. H-Tyr(3-I)-OH is an intermediate in the production of thyroid hormones and has a role as a human or mouse metabolite[1][2].
|
-
- HY-79131S3
-
|
Fmoc-Phe-OH- 15N is a 15N-labeled Propoxur.
|
-
- HY-Y1250S1
-
|
Fmoc-Gly-OH-2- 13C, 15N is the 13C, 15N labeled Fmoc-Gly-OH-2[1].
|
-
- HY-W009204S1
-
|
Fmoc-Ala-OH-3,3,3-d3 is the deuterium labeled Fmoc-Ala-OH-3,3,3[1].
|
-
- HY-W101495S3
-
|
Boc-Leu-OH·H2O-d7 is the deuterium labeled Boc-Leu-OH·H2O.
|
-
- HY-79131S1
-
|
Fmoc-Phe-OH- 13C9, 15N is a 15N-labeled and 13C-labled Fmoc-Ala-OH[1].
|
-
- HY-W008371S1
-
|
Fmoc-Met-OH- 13C5, 15N is a 15N-labeled and 13C-labled Fmoc-L-Val-OH[1].
|
-
- HY-W009204S4
-
|
Fmoc-Ala-OH- 13C3, 15N is a 15N-labeled and 13C-labled Fmoc-Aib-OH[1].
|
-
- HY-Y1169S1
-
|
Fmoc-Asp(OtBu)-OH- 13C4, 15N is the 13C and 15N labeled Fmoc-Asp(OtBu)-OH[1]. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis[2].
|
-
- HY-W101495S1
-
|
Boc-Leu-OH·H2O-d3 is the deuterium labeled Boc-Leu-OH·H2O[1].
|
-
- HY-W101495S2
-
|
Boc-Leu-OH·H2O-d10 is the deuterium labeled Boc-Leu-OH·H2O[1].
|
-
- HY-19821S
-
|
Fmoc-Ile-OH- 15N is the 15N labeled Fmoc-Ile-OH[1].
|
-
- HY-W010921S
-
|
Fmoc-Trp-OH- 13C11, 15N2 is a 15N-labeled and 13C-labled Fmoc-Pro-OH[1].
|
-
- HY-W013780S2
-
|
Fmoc-Pro-OH- 15N is a 15N-labeled Glycine ethyl ester monohydrochloride[1].
|
-
- HY-W007941S
-
|
Fmoc-Ser(tBu)-OH- 13C3, 15N is a 15N-labeled and 13C-labled Fmoc-L-Lys (Boc)-OH[1].
|
-
- HY-W012479S
-
|
H-D-Trp-OH-d5 (D-Tryptophan-d5) is the deuterium labeled H-D-Trp-OH. H-D-Trp-OH is a D-stereoisomer of tryptophan and occasionally found in naturally produced peptides such as the marine venom peptide.
|
-
- HY-P4596S
-
|
H-Gly-Arg-OH (Arg- 13C6, 15N 4)is the deuterium labeledH-Gly-Arg-OH(HY-P4596) .
|
-
- HY-P4596S1
-
|
H-Gly-Arg-OH (Arg- 13C6, 15N 4) TFAis the deuterium labeledH-Gly-Arg-OH(HY-P4596) .
|
-
- HY-W007798S
-
|
Fmoc-Cys(Trt)-OH-1,2,3- 13C3, 15N is a 15N-labeled and 13C-labled Fmoc-Phe-OH[1].
|
-
- HY-W012908S
-
|
H-DL-Pro-OH-d7 is the deuterium labeled 5-(Dimethylamino)naphthalene-1-sulfonic acid[1].
|
-
- HY-I1111S1
-
|
Fmoc-L-Val-OH-1- 13C is a 13C-labeled Carbaryl. Carbaryl is used chiefly as an insecticide[1].
|
-
- HY-19821S1
-
|
Fmoc-Ile-OH- 13C6, 15N is the 13C and 15N labeled Fmoc-Ile-OH[1]. Fmoc-Ile-OH is an isoleucine derivative[2].
|
-
- HY-41121S1
-
|
Boc-L-Ala-OH-3- 13C is a 13C-labeled Hypoxanthine. Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.
|
-
- HY-W013780S
-
|
Fmoc-Pro-OH-1- 13C is a 13C-labeled Sulfabenzamide. Sulfabenzamide (N-Sulfanilylbenzamide) is an antimicrobial agent and usually consumed in combination with Sulfathiazole and Sulfacetamide. Sulfabenzamide is effective against Gram-positive and negative ba
|
-
- HY-W008642S
-
|
(Leu-13C6,15N)-Leu-OH TFA is a C13 and N15 labeled Leu-Leu-OH TFA. Leu-Leu-OH, a Leu derivative, is a dipeptide .
|
-
- HY-I1111S4
-
|
Fmoc-L-Val-OH- 15N is a 15N-labeled Leucomalachite green. Leucomalachite green is a triphenylmethane dye used to detect blood. Leucomalachite green, a major metabolite of malachite green, is a potential carcinogen, teratogen and mutagen[1][2].
|
-
- HY-W007706S
-
|
Fmoc-Thr(tBu)-OH- 13C4, 15N is a 15N-labeled and 13C-labled 2-Acetamidobenzamide[1].
|
-
- HY-Y1250S4
-
|
Fmoc-Gly-OH-1- 13C is a 13C-labeled Carbendazim. Carbendazim is a potent and orally active broad-spectrum benzimidazole fungicide and can be acts as a pesticide for fungal diseases research, such as Seproria, Fusarium and Sclerotina[1][3]. Carbendazim is a
|
-
- HY-W101495S
-
|
Boc-Leu-OH·H2O- 13C is a 13C-labeled γ-Tocotrienol. γ-Tocotrienol is an active form of vitamin E[1].
|
-
- HY-W052227S
-
|
Fmoc-DL-Ala-OH-d is the deuterium labeled DL-Alanine-2-N-fmoc.
|
-
- HY-79128S1
-
|
Fmoc-L-Lys (Boc)-OH- 13C6, 15N2 is a 15N-labeled and 13C-labled Triclabendazole.
|
-
- HY-W009204S5
-
|
Fmoc-Ala-OH- 13C3 is a 13C-labeled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-ind
|
-
- HY-W014423S4
-
|
L-Histidine-d5 (hydrochloride hydrate) is the deuterium labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
|
-
- HY-W014423S
-
|
L-Histidine- 13C (hydrochloride hydrate) is the 13C-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
|
-
- HY-W014423S6
-
|
L-Histidine- 15N (hydrochloride hydrate) is the 15N-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
|
-
- HY-W014423S7
-
|
L-Histidine-d3 (hydrochloride hydrate)eis the deuterium labeled L-Histidine (hydrochloride hydrate). L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
|
-
- HY-W008016S
-
|
Fmoc-Tyr(tBu)-OH- 13C9, 15N is a 15N-labeled and 13C-labled Hypoxanthine. Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.
|
-
- HY-W012874S
-
|
D-Threonine-d2 is the deuterium labeled D-Threonine. D-Threonine (H-D-Thr-OH) is an enantiomer of L-threonine. D-Threonine is a metabolite of Saccharomyces cerevisiae.
|
-
- HY-136440S
-
|
Hydroxymetronidazole-d4 is the deuterium labeled Hydroxymetronidazole. Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle[1].
|
-
- HY-W013780S1
-
|
Fmoc-Pro-OH- 13C5, 15N is a 15N-labeled and 13C-labled Pyrimethanil. Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops[1]. Pyrimethanil inhibits the biosynthesis of methioni
|
-
- HY-I1111S2
-
|
Fmoc-L-Val-OH- 13C5, 15N is a 15N-labeled and 13C-labled Pirimicarb. Pirimicarb is a fast-acting selective carbamate insecticide on a wide range of crops including cereals, sugar beet, potatoes, fruits and vegetables. Pirimicarb is an AChE inhibitor and an
|
-
- HY-W101298S
-
|
(Leu-13C6,15N)-Ile-OH (L-Leucyl-13C6,15N-L-isoleucine) TFA is the deuterium labeled Leu-Ile-OH. Leu-Ile-OH protects against neuronal death by inducing brain-derived neurotrophic factor (BDNF) and glial cell line-derived neurotrophic factor (GDNF) synthesis .
|
-
- HY-W014423S2
-
|
L-Histidine- 13C6 (hydrochloride hydrate) is the 13C-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
|
-
- HY-W014423S5
-
|
L-Histidine- 15N3 (hydrochloride hydrate) is the 15N-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
|
-
- HY-W002327S
-
|
Fmoc-Asn(Trt)-OH- 13C4, 15N2 is a 15N-labeled and 13C-labled 4-(4-(tert-Butyl)-2-ethoxyphenyl)-2-(2,6-difluorophenyl)-4,5-dihydrooxazole[1].
|
-
- HY-W014423S3
-
|
L-Histidine- 13C6, 15N3 (hydrochloride hydrate) is the 13C- and 15N-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
|
-
- HY-W269700S
-
|
Ile-(Leu-13C6,15N)-OH (TFA) is 13C- and 15N-labeled L-Isoleucyl-L-leucine (HY-W269700). L-Isoleucyl-L-leucine has a role as a metabolite and can be used to inhibit movement-induced muscle damage and muscle defective condition.
|
-
- HY-W014423S1
-
|
L-Histidine- 13C6, 15N3,d5 (hydrochloride hydrate) is the deuterium, 13C-, and 15-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
|
-
- HY-W012340S
-
|
L-Homoarginine- 13C7, 15N4 (hydrochloride) is the 13C- and 15N-labeled H-HomoArg-OH.HCl. H-HomoArg-OH.HCl is an endogenous metabolite.
|
-
- HY-130321S1
-
|
Lauroyl-L-carnitine-d9 (chloride) is the deuterium labeled Boc-L-Ala-OH[1].
|
-
- HY-B2048S
-
|
Pencycuron-d5 is the deuterium labeled H-DL-Abu-OH[1].
|
-
- HY-D0300S1
-
|
Leucomalachite green-d6 is the deuterium labeled Fmoc-Gly-OH[1].
|
-
- HY-W015339S
-
|
Octanoate- 13C (sodium) is a 13C-labeled Fmoc-Gly-OH[1].
|
-
- HY-W134007S
-
|
Hexadecanoate- 13C (potassium) is a 13C-labeled Fmoc-L-Val-OH[1].
|
-
- HY-W286743S
-
|
CML-d4 is the deuterium labeled Fmoc-L-Lys (Boc)-OH[1].
|
-
- HY-Z3421S
-
|
Vonoprazan-d3 (fumarate) is the deuterium labeled Fmoc-Cys(Trt)-OH[1].
|
-
- HY-W321016S
-
|
SWEP-d3 is the deuterium labeled Fmoc-Tyr(tBu)-OH[1].
|
-
- HY-W002071S
-
|
2-Quinoxalinecarboxylic acid-d4 is the deuterium labeled Fmoc-Pro-OH[1].
|
-
- HY-Y0869S
-
|
4-Methoxybenzylamine-d3 is the deuterium labeled Fmoc-Ser(tBu)-OH[1].
|
-
- HY-N0091S2
-
|
Hypoxanthine- 13C5 is a 13C-labeled H-Lys-OH.2HCl[1].
|
-
- HY-W278362S
-
|
2-Acetamidobenzamide-d3 is the deuterium labeled H-Lys-OH.2HCl[1].
|
-
- HY-Y0978S3
-
|
Boc-Glycine- 13C is a 13C-labeled H-Lys-OH.2HCl[1].
|
-
- HY-116285S
-
|
n-Octyl β-D-glucopyranoside-d24 is the deuterium labeled Fmoc-L-Val-OH[1].
|
-
- HY-124547S
-
|
2,4-D methyl ester-d3 is the deuterium labeled Fmoc-Trp-OH[1].
|
-
- HY-W101563S
-
|
Propan-2-amine-d6 (hydrochloride) is the deuterium labeled H-Lys-OH.2HCl[1].
|
-
- HY-W011012S
-
|
Adenosine 5'-monophosphate- 13C (disodium) is a 13C-labeled H-Lys-OH.2HCl[1].
|
-
- HY-W018386S
-
|
3-Bromo-L-tyrosine- 13C6 is a 13C-labeled H-Lys-OH.2HCl[1].
|
-
- HY-W011012S1
-
|
Adenosine 5'-monophosphate-d2 (disodium) is the deuterium labeled Boc-Leu-OH·H2O[1].
|
-
- HY-Y1250S6
-
|
Fmoc-Gly-OH- 13C2, 15N is a 15N-labeled and 13C-labled Crystal Violet. Crystal violet (Basic Violet 3) is a triarylmethane dye. Crystal Violet (Gentian Violet) has antiviral effects against H1N1 and also has prominent bactericidal activities.
|
-
- HY-W098722S
-
|
3-(4-Chlorophenyl)-1-methoxy-1-methylurea-d6 is the deuterium labeled H-Lys-OH.2HCl[1].
|
-
- HY-141902S
-
|
FMOC-L-Glutamic Acid- 13C5, 15N-5-t-butyl ester is the 13C and 15N labeled FMOC-L-Glutamic Acid-5-t-butyl ester[1].
|
-
- HY-135212S
-
|
Hydroxy ipronidazole-d3 is the deuterium labeled Hydroxy ipronidazole. Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound[1].
|
-
- HY-W014423S8
-
|
L-Histidine- 15N3,d5 (hydrochloride hydrate) is the deuterium and 15N labeled L-Histidine hydrochloride hydrate[1]. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
|
-
- HY-111975S1
-
|
7'-Hydroxy ABA-d22 is the deuterium labeled 7'-Hydroxy ABA[1].
|
-
- HY-111975S5
-
|
7'-Hydroxy ABA-d7 is the deuterium labeled 7'-Hydroxy ABA[1].
|
-
- HY-151930S
-
|
8′-Hydroxy ABA-d8 is the deuterium labeled 8’-Hydroxy ABA[1].
|
-
- HY-151930S1
-
|
8′-Hydroxy ABA-d2 is the deuterium labeled 8’-Hydroxy ABA[1].
|
-
- HY-U00050S
-
|
(E)-10-Hydroxynortriptyline-d3 is a deuterium labeled (E)-10-Hydroxy Nortriptyline. (E)-10-Hydroxy Nortriptyline is a metabolite of Nortriptyline. Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1].
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-
- HY-W015824S2
-
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DL-Aspartic acid-3- 13C is the 13C labeled DL-Aspartic acid[1].
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-
- HY-113482S
-
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1β-Hydroxydeoxycholic Acid-d5 is the deuterium labeled 1β-Hydroxydeoxycholic Acid[1].
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-
- HY-W015824S3
-
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DL-Aspartic acid- 13C1 is the 13C labeled DL-Aspartic acid[1].
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-
- HY-W015824S1
-
|
DL-Aspartic acid- 13C, 15N is the 13C, and 15N-labeled DL-Aspartic acid.
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-
- HY-W015824S5
-
|
DL-Aspartic acid- 13C, 15N-1 hydrochloride is the 13C and 15N labeled DL-Aspartic acid.
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-
- HY-113031S
-
|
16α-Hydroxydehydroepiandrosterone-d5 (16α-Hydroxy-DHEA-d5) is the deuterium labeled 16α-Hydroxydehydroepiandrosterone[1].
|
-
- HY-146659S
-
|
S-Phenyl-DL-cysteine-3,3-d2 is the deuterium labeled S-Phenyl-DL-cysteine-3,3[1].
|
-
- HY-N7404S
-
|
Nε,Nε,Nε-Trimethyllysine-d9 (chloride) is the deuterium labeled Nε,Nε,Nε-Trimethyllysine (chloride)[1]. Nε,Nε,Nε-Trimethyllysine chloride serves as a precursor for gut flora-dependent formation of N,N,N-trimethyl-5-aminovaleric acid (TMAVA)[2].
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-
Cat. No. |
Product Name |
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Classification |
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- HY-117045
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|
PROTAC Synthesis
Alkynes
|
Propargyl-PEG12-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG12-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130147
-
|
|
PROTAC Synthesis
Alkynes
|
Propargyl-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG5-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-151778
-
|
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Azide
|
Fmoc-Abg(N3)-OH is a click chemistry reagent containing an azide group. Fmoc-Abg(N3)-OH has the potential to synthesize peptide nucleic acids (PNA) and peptoids.
|
-
- HY-126977
-
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|
Alkynes
PROTAC Synthesis
|
Propargyl-PEG9-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG9-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130374
-
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|
PROTAC Synthesis
Alkynes
|
Propargyl-PEG8-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG8-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-138735
-
|
|
Alkynes
PROTAC Synthesis
|
Propargyl-PEG13-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG13-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-151694
-
|
|
Azide
|
H-L-Orn(N3)-OH (hydrochloride) is a click chemistry reagent containing an azide group. H-L-Orn(N3)-OH (hydrochloride) can be used for the research of various biochemical .
|
-
- HY-151660
-
|
|
Azide
|
Fmoc-D-Lys(N3)-OH is a click chemistry reagent containing an azide group. Fmoc-D-Lys(N3)-OH can be used for the research of various biochemical .
|
-
- HY-151732
-
|
|
Azide
|
Z-D-Dbu(N3)-OH is a click chemistry reagent containing an azide group. Z-D-Dbu(N3)-OH can be used for the research of various biochemical .
|
-
- HY-130925
-
|
|
ADC Synthesis
BCN
|
BCN-PEG4-OH is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG4-OH is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-130541
-
|
|
Alkynes
PROTAC Synthesis
|
Propargyl-PEG2-OH is a PEG-based PROTAC linker can be used in the synthesis of Thalidomide-O-PEG2-propargyl (HY-126458) . Propargyl-PEG2-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-138521
-
|
|
ADC Synthesis
Azide
|
Azido-C6-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-C6-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-151652
-
|
|
Alkynes
|
Boc-L-Cys(Propargyl)-OH is a click chemistry reagent. Boc-L-Cys(Propargyl)-OH can be used for the research of various biochemical .
|
-
- HY-151785
-
|
|
Azide
|
H-L-Dbu(N3)-OH is a click chemistry reagent containing an azide group .
|
-
- HY-141186
-
|
|
TCO
|
TCO-OH is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W011210
-
|
|
Alkynes
|
Fmoc-Pra-OH is a Glycine (HY-Y0966) derivative . Fmoc-Pra-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-151671
-
|
|
Azide
|
Fmoc-L-MeLys(N3)-OH is a click chemistry reagent containing an azide. Fmoc-L-MeLys(N3)-OH is a SPPS building-block for the introduction of N-Me-Lys that can be modified at the N3-group using Click-chemistry . Fmoc-L-MeLys(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-151684
-
|
|
Alkynes
|
Boc-Ser(O-propargyl)-OH is a click chemistry reagent containing an alkynes group. Boc-Ser(O-propargyl)-OH can be used for the research of various biochemical .
|
-
- HY-W250992
-
|
|
Azide
|
Boc-L-Lys(N3)-OH CHA is a click chemistry reagent containing an azide .
|
-
- HY-151722
-
|
|
Azide
|
Boc-D-Orn(N3)-OH (CHA) is a click chemistry reagent containing an azide group.
|
-
- HY-151737
-
|
|
Azide
|
Z-L-Dbu(N3)-OH is a click chemistry reagent containing an Azide . Z-L-Dbu(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-151652A
-
|
|
Alkynes
|
Boc-L-Cys(Propargyl)-OH (DCHA) is a click chemistry reagent. Boc-L-Cys(Propargyl)-OH (DCHA) can be used for the research of various biochemical .
|
-
- HY-151733
-
|
|
Azide
|
Fmoc-D-Dbu(N3)-OH is a click chemistry reagent containing an Azide . Fmoc-D-Dbu(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-151703
-
|
|
Azide
|
Boc-D-Lys(N3)-OH is a Boc-protected amino acid derivative, can be used as a click chemistry reagent and an intermediate for synthesis of linkers .
|
-
- HY-141186A
-
|
|
TCO
|
(R)-TCO-OH is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W008395
-
|
|
Alkynes
|
Fmoc-D-Pra-OH is a Glycine (HY-Y0966) derivative . Fmoc-D-Pra-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-151668
-
|
|
Azide
|
Z-L-Aha-OH is a click chemistry reagent containing azide group .
|
-
- HY-151723
-
|
|
Azide
|
H-D-Aha-OH (hydrochloride) is a click chemistry reagent containing an azide group.
|
-
- HY-151709
-
|
|
Azide
ADC Synthesis
|
N3-L-Cit-OH is a click chemistry reagent containing an azide group. N3-L-Cit-OH can be used to construct peptidomimetic ADC linkers using Click-chemistry .
|
-
- HY-140808
-
|
|
PROTAC Synthesis
Azide
|
Azido-PEG3-C3-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-C3-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-138471
-
|
|
Azide
PROTAC Synthesis
|
Azido-PEG2-C6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG2-C6-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-151718
-
|
|
Azide
|
Boc-L-Tyr(PEG(3)-N3)-OH is a click chemistry agent containing azide.
|
-
- HY-151693A
-
|
|
Azide
|
H-L-Tyr(2-azidoethyl)-OH is a unnatural Tyrosine derivative. H-L-Tyr(2-azidoethyl)-OH is a click chemistry reagent containing an azide group .
|
-
- HY-151693
-
|
|
Azide
|
H-L-Tyr(2-azidoethyl)-OH hydrochloride is a unnatural Tyrosine derivative. H-L-Tyr(2-azidoethyl)-OH hydrochloride is a click chemistry reagent containing an azide group .
|
-
- HY-130935
-
|
|
DBCO
ADC Synthesis
|
DBCO-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Val-Cit-OH is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-W142062
-
|
|
Azide
|
cis-Fmoc-Pro(4-N3)-OH is a proline derivative . cis-Fmoc-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-151675
-
|
|
Azide
|
H-L-Tyr(3-N3)-OH is a click chemistry reagent containing an azide . H-L-Tyr(3-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-151735
-
|
|
Azide
|
N3-L-Dab(Boc)-OH is a click chemistry reagent containing an azide group. N3-L-Dab(Boc)-OH can be used for the research of various biochemical .
|
-
- HY-151682
-
|
|
TCO
Labeling and Fluorescence Imaging
|
H-L-Lys(Norbornene-methoxycarbonyl)-OH, a norbornene-derivatized lysine, can be click-functionalized. H-L-Lys(Norbornene-methoxycarbonyl)-OH can be used for the mild and selective modification of proteins in a copper-free click reaction .
|
-
- HY-151682A
-
|
|
TCO
Labeling and Fluorescence Imaging
|
H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride, a norbornene-derivatized lysine, can be click-functionalized. H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride can be used for the mild and selective modification of proteins in a copper-free click reaction .
|
-
- HY-151763
-
|
|
Azide
|
Boc-L-Aza-OH CHA is a click chemistry reagent containing an azide group.
|
-
- HY-151668A
-
|
|
Azide
|
Z-L-Aha-OH (DCHA) is a click chemistry reagent containing azide group .
|
-
- HY-151683
-
|
|
Alkynes
|
H-L-Ser(Propargyl)-OH is a click chemistry reagent containing an alkyne group .
|
-
- HY-151683A
-
|
|
Alkynes
|
H-L-Ser(Propargyl)-OH hydrochloride is a click chemistry reagent containing an alkyne group .
|
-
- HY-140809
-
|
|
PROTAC Synthesis
Azide
|
Azido-PEG4-(CH2)3OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-(CH2)3OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-151718A
-
|
|
Azide
|
Boc-L-Tyr(PEG(3)-N3)-OH DCHA is a click chemistry reagent containing an azide group.
|
-
- HY-151715
-
|
|
Azide
|
N3-D-Dap(Fmoc)-OH is a click chemistry reagent. N3-D-Dap(Fmoc)-OH can be used as a component for coupling by click reaction and as an orthogonally protected diaminocarboxylic acid derivative .
|
-
- HY-151709A
-
|
|
Azide
ADC Synthesis
|
N3-L-Cit-OH DCHA is a click chemistry reagent containing an azide group. N3-L-Cit-OH DCHA can be used to construct peptidomimetic ADC linkers using Click-chemistry .
|
-
- HY-151689
-
|
|
Azide
|
(2S,3R)-Fmoc-Abu(3-N3)-OH is a click chemistry reagent containing an azide group. (2S,3R)-Fmoc-Abu(3-N3)-OH can be used for the research of various biochemical .
|
-
- HY-151678
-
|
|
Azide
|
N3-L-Lys(Mtt)-OH is a click chemistry reagent containing an azide group. N3-L-Lys(Mtt)-OH can introduce azide functions into the amino acid building block of peptide sequences at the N-terminal position.
|
- HY-130936
-
|
|
DBCO
ADC Synthesis
|
DBCO-Val-Cit-PABC-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Val-Cit-PABC-OH is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-151780
-
|
|
Alkynes
|
Fmoc-L-Dap(Pentynoyl)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Dap(Pentynoyl)-OH serves as an amino acid building block for introducing alkyne functions into peptide sequences by standard Fmoc/tBu protocols. The alkyne residue can be engaged for copper catalyzed click reaction with organic azides or with tetrazines for copper-free conjugations . Fmoc-L-Dap(Pentynoyl)-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-151669
-
|
|
Azide
|
Fmoc-D-Aha-OH is a click chemistry reagent containing an azide . Fmoc-D-Aha-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
- HY-151658
-
|
|
Azide
|
H-L-Lys(N3-Gly)-OH is a click chemistry containing an azide group, a lysine derivative. H-L-Lys(N3-Gly)-OH can be incorporated into proteins for click modifications .
|
- HY-151658A
-
|
|
Azide
|
H-L-Lys(N3-Gly)-OH hydrochloride is a click chemistry containing an azide group, a lysine derivative. H-L-Lys(N3-Gly)-OH hydrochloride can be incorporated into proteins for click modifications .
|
- HY-151639
-
|
|
Azide
|
(2S,4R)-H-L-Pro(4-N3)-OH is a click chemistry reagent containing an azide group. (2S,4R)-H-L-Pro(4-N3)-OH can be used for the research of various biochemical studies .
|
- HY-151639A
-
|
|
Azide
|
(2S,4R)-H-L-Pro(4-N3)-OH (hydrochloride) is a click chemistry reagent containing an azide group. (2S,4R)-H-L-Pro(4-N3)-OH (hydrochloride) can be used for the research of various biochemical studies .
|
- HY-151684A
-
|
|
Alkynes
|
Boc-Ser(O-propargyl)-OH (DCHA) is a click chemistry reagent containing a propynyl group.
|
- HY-151664
-
|
|
Alkynes
|
H-alpha-Prg-D-Ala-OH is a click chemistry reagent containing an azide group .
|
- HY-151734
-
|
|
Azide
|
(2R,3S)-Fmoc-Abu(3-N3)-OH is a click chemistry reagent containing an azide group .
|
- HY-151761
-
|
|
Azide
Labeling and Fluorescence Imaging
|
H-L-Lys(4-N3-Z)-OH hydrochloride is a click chemistry reagent containing an azide group. H-L-Lys(4-N3-Z)-OH hydrochloride contains a lysine-modified azide moiety and as a bioorthogonal ligation handle. H-L-Lys(4-N3-Z)-OH hydrochloride is an infrared probe and a photo-affinity reagent .
|
- HY-151661
-
L-azidovaline (CHA)
|
|
Azide
|
N3-L-Val-OH (CHA) is a click chemistry containing an azide group, a valine derivative. N3-L-Val-OH (CHA) can also be used as a synthetic intermediate for Valaciclovir (Valacyclovir) .
|
- HY-151721
-
|
|
Azide
|
H-D-Orn(N3)-OH hydrochloride is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
- HY-151785A
-
|
|
Azide
|
H-L-Dbu(N3)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
- HY-151849
-
|
|
Azide
|
Z-L-Dap(N3)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
- HY-151858
-
|
|
Azide
|
Boc-L-Lys(N3)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
- HY-151748
-
|
|
Azide
|
N3-L-Orn(Fmoc)-OH is a Fmoc-protected ornithine derivative, can be used as a click chemistry reagent.
|
- HY-151760A
-
|
|
Azide
|
(2R,4S)-H-D-Pro(4-N3)-OH hydrochloride is a click chemistry reagent containing an azide group.
|
- HY-151762
-
|
|
Azide
|
(2R,4S)-Fmoc-D-Pro(4-N3)-OH is a click chemistry reagent containing an azide group.
|
- HY-151848
-
|
|
Azide
|
(2R,4R)-Boc-D-Pro(4-N3)-OH is a click chemistry reagent containing an azide group.
|
- HY-130922
-
|
|
BCN
ADC Synthesis
|
BCN-PEG1-Val-Cit-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG1-Val-Cit-OH is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-151786
-
|
|
Azide
|
Fmoc-L-Lys(Pentynoyl-DIM)-OH is a click chemistry reagent containing an azide. Fmoc-L-Lys(Pentynoyl-DIM)-OH can be used as a SPPS building block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution .
|
- HY-151738
-
|
|
Azide
|
Fmoc-Aeg(N3)-OH is a click chemistry reagent containing an Azide. Alkylating the Nitrogen of an amide bond results in peptoid structures, which leads to conformational restrains, like N-methylation and allows backbone derivatisation. Altering cytotoxicity, bacterial cell selectivity and receptor pharmacology through formation of peptoid derivatives have been published for Cilengitide, Piscidin 1, and MC3, MC4 and MC5 receptor agonist. This building block enables design of macrocycles through intermolecular crosslinking or backbone stabilization through intermolecular ring-closure. This compound is a potential building block for the construction of (customized) peptide nucleic acids (PNAs) and for peptoid synthesis . Fmoc-Aeg(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
- HY-151674
-
|
|
Azide
|
N3-L-Cys(Trt)-OH (CHA) is a click chemistry reagent containing an azide group.
|
- HY-130934
-
|
|
ADC Synthesis
TCO
|
TCO-PEG1-Val-Cit-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG1-Val-Cit-OH is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
- HY-151836
-
|
|
Azide
|
(2S,3R)-H-Abu(3-N3)-OH (hydrochloride) is a click chemistry reagent containing an azide group . (2S,3R)-H-Abu(3-N3)-OH (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
- HY-151838
-
|
|
Azide
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(2S,3S)-H-Abu(3-N3)-OH (hydrochloride) is a click chemistry reagent containing an azide group . (2S,3S)-H-Abu(3-N3)-OH (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-151731
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Azide
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N3-1,4-trans-CHC-OH is a click chemistry reagent containing an azide group.
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- HY-151653
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O-Propargyl-D-tyrosine
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Alkynes
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H-D-Tyr(Propargyl)-OH is a click chemistry reagent containing an Azide . H-D-Tyr(Propargyl)-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-151687
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Azide
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Fmoc-L-Tyr(2-azidoethyl)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Tyr(2-azidoethyl)-OH is unnatural Fmoc-protected Tyrosine derivative bears an azidoethyl substitution as reactive handle e.g. for biorthogonal conjugations, via a Cu(I)-catalyzed 1,3-dipolar Click cycloaddition with alkynes. And azido-UAAs can be employed as IR reporters .
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- HY-151703A
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Azide
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Boc-D-Lys(N3)-OH CHA is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
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- HY-151677
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Azide
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(2R,4S)-Boc-D-Pro(4-N3)-OH is a click chemistry reagent containing an azide . (2R,4S)-Boc-D-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-151850
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Azide
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(2S,4R)-Fmoc-L-Pro(4-N3)-OH is a click chemistry reagent containing an azide . (2S,4R)-Fmoc-L-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-151826
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Alkynes
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Fmoc-D-Lys(pentynoyl)-OH is a click chemistry reagent containing an azide group. Used to introduce alkyne functionality into peptides that can be further modified using Click-chemistry .
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- HY-151654
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Azide
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N3-D-Lys(Boc)-OH is a click chemistry reagent containing an Azide . N3-D-Lys(Boc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-151729
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Azide
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N3-D-Dab(Boc)-OH is a click chemistry reagent containing an Azide . N3-D-Dab(Boc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-151841
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Azide
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N3-L-Lys(Boc)-OH is a click chemistry reagent containing an azide group . N3-L-Lys(Boc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-151843
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Azide
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N3-L-Lys(Fmoc)-OH is a click chemistry reagent containing an azide group . N3-L-Lys(Fmoc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-130923
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BCN
ADC Synthesis
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BCN-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-PEG1-Val-Cit-PABC-OH is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-140149
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Azide
PROTAC Synthesis
ADC Synthesis
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Azido-PEG4-Val-Cit-PAB-OH is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG4-Val-Cit-PAB-OH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-Val-Cit-PAB-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-151760
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Azide
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(2R,4S)-H-D-Pro(4-N3)-OH is a click chemistry reagent containing an azide group . (2R,4S)-H-D-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-151839
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Azide
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(2R,4R)-H-D-Pro(4-N3)-OH (hydrochloride) is a click chemistry reagent containing an azide group . (2R,4R)-H-D-Pro(4-N3)-OH (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-130966
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TCO
ADC Synthesis
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TCO-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG1-Val-Cit-PABC-OH is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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- HY-151777
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Azide
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N3-Gly-Gly-Gly-Gly-Gly-OH is a click chemistry reagent containing an azide group.
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- HY-136034
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Azide
ADC Synthesis
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Azido-PEG1-Val-Cit-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG1-Val-Cit-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-151677A
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Azide
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(2R,4S)-Boc-D-Pro(4-N3)-OH DCHA is a click chemistry reagent containing an azide . (2R,4S)-Boc-D-Pro(4-N3)-OH (DCHA) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-151828
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Azide
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N3-Gly-Aeg(Fmoc)-OH is a click chemistry reagent containing an azide group. PNA building-block that can be further modified using Click-chemistry .
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- HY-151781
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Alkynes
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Fmoc-L-Dap(Poc)-OH is a click chemistry reagent containing an azide group. Amino acid building block suitable for side chain Click conjugation with standard protocols and together with tetrazine linkers in copper-free Click conjugation (Diels-Alder) .
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- HY-151764
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ADC Synthesis
Azide
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N3-D-Orn(Boc)-OH is a Boc-protected pentanoic amino acid derivative, can be used as a click chemistry reagent and has been used to synthesis antibody-drug conjugates (ADC) .
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- HY-151829
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Azide
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Fmoc-L-Asn(EDA-N3)-OH is a click chemistry reagent containing an azide group. This building block is reported in literature for the modification of Amanitin via Click Chemistry. Alpha-Amanitin is the deadliest member of the amatoxin peptide family produced by the death-cap mushroom A. phalloides. It is an orally available, rigid, bicyclic octapeptide and one of the most lethal known natural products (LD50 = 50-100 μg/kg) acting as highly selective allosteric inhibitor of the RNA polymerase II .
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- HY-151736
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Azide
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N3-L-Dap(Boc)-OH is a click chemistry reagent containing an azide group. Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompatible, rapid and highly specific in biological environments . N3-L-Dap(Boc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-151749
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Azide
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N3-D-Lys(Fmoc)-OH is a click chemistry reagent containing an azide group. Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompatible, rapid and highly specific in biological environments . N3-D-Lys(Fmoc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-151659
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Azide
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Fmoc-L-Lys(N3-Gly)-OH is a click chemistry reagent containing a lysine-containing azidoacetyl group building-block for SPPS and can be used for various biochemical studies .
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- HY-140148
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Azide
ADC Synthesis
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Azido-PEG3-Val-Cit-PAB-OH is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG3-Val-Cit-PAB-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-136137
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Azide
ADC Synthesis
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Azide-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azide-PEG1-Val-Cit-PABC-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-151784
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Azide
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Boc-D-Aza-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
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- HY-140569
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Alkynes
PROTAC Synthesis
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N-(PEG1-OH)-N-Boc-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(PEG1-OH)-N-Boc-PEG2-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-151679
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Azide
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Fmoc-L-Lys(4-N3-Z)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Lys(4-N3-Z)-OH acts as Lysine building-block for SPPS containing an Azide moiety as a bioorthogonal ligation handle, an infrared probe and a photo-affinity reagent. It can be decaged by trans-cyclooctenols via a strain-promoted 1,3-dipolar cycloaddition . Fmoc-L-Lys(4-N3-Z)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-151845
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Azide
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N3-PhAc-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
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- HY-151764A
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Azide
ADC Synthesis
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N3-D-Orn(Boc)-OH (CHA) is a Boc-protected pentanoic amino acid derivative, can be used as a click chemistry reagent and has been used to synthesis antibody-drug conjugates (ADC) .
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- HY-W419403
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Azide
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Boc-D-Aza-OH (CHA) is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
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- HY-151814
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Alkynes
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(2S,4S)-Fmoc-L-Pro(4-NHPoc)-OH is a click chemistry reagent containing an azide group.
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- HY-151846
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Alkynes
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Boc-L-Pra-OH (DCHA) is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
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- HY-151859
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Azide
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N3-Gly-Gly-OH is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
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- HY-151865A
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Azide
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(2S,4S)-H-L-Pro(4-N3)-OH (hydrochloride) is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
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- HY-151825
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Alkynes
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Fmoc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent containing an azide group. Used as an orthogonally protected building block in solid-phase peptide synthesis. Poc-group can be further modified using Click-chemistry .
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- HY-151746
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Azide
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N3-Gly-Gly-Gly-OH is a oligo-Gly click chemistry reagent containing an azide group. Oligo-Gly also has been used as linker to combine different subunits of dimeric or oligomeric proteins or to create artificial multi-domain proteins. By modification into Gly-Gly-Gly-Ser motifs high solubility can be achieved . N3-Gly-Gly-Gly-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-151865
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Azide
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(2S,4S)-H-L-Pro(4-N3)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
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- HY-151861
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Azide
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N3-Aca-Aca-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
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- HY-151650
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Azide
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N3-O2Oc-O2Oc-OH is a click chemistry reagent containing an azide . N3-O2Oc-O2Oc-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-151853A
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Azide
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N3-L-Leu-OH (BHA) is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
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- HY-151681
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cis-4-Azido-N-Fmoc-D-proline
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Azide
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(2R,4R)-Fmoc-D-Pro(4-N3)-OH (cis-4-Azido-N-Fmoc-D-proline) is a click chemistry reagent containing an azide group .
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- HY-151859A
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Azide
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N3-Gly-Gly-OH (DCHA) is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
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- HY-151779
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Azide
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N3-L-Dab(Fmoc)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
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- HY-151676
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N-Boc-O-(2-azidoethyl)-L-tyrosine
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Azide
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Boc-L-Tyr(2-azidoethyl)-OH (N-Boc-O-(2-azidoethyl)-L-tyrosine) is a click chemistry reagent containing an azide group .
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- HY-151824
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Alkynes
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Boc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent containing an azide group. Used as an orthogonally protected building block in peptide synthesis. Propargyloxycarbonyl, commonly abbreviated as Poc or Pryoc, can either be used as alkyne component for standard Click conjugation or in combination with tetrazine linkers in copper-free Diels-Alder type Click reactions. It also has applications as unusual protecting group for amines, hydroxy functions and as esters. All 3 are stable to neat TFA, but can be cleaved at ambient temperature with Co2(CO)8 in TFA:DCM. Deprotection with other transition metals like palladium have also been reported . Boc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-151837
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Alkynes
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H-L-Phe(4-NH-Poc)-OH (hydrochloride) is a click chemistry reagent containing an azide group. Used as a modified Phe or Tyr analogue in protein and peptide biosynthesis. Propargyloxycarbonyl, commonly abbreviated as Poc or Pryoc, can either be used as alkyne component for standard Click conjugation or in combination with tetrazine linkers in copper-free Diels-Alder type Click reactions. It also has applications as unusual protecting group for amines, hydroxy functions and as esters. All 3 are stable to neat TFA, but can be cleaved at ambient temperature with Co2(CO)8 in TFA:DCM. Deprotection with other transition metals like palladium have also been reported . H-L-Phe(4-NH-Poc)-OH (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-151856
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Azide
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N3-1,4-cis-CHC-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
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- HY-151695
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N2-Fmoc-N6-[(propargyloxy)carbonyl]-L-lysine
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Alkynes
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Fmoc-L-Lys(Pryoc)-OH (N2-Fmoc-N6-[(propargyloxy)carbonyl]-L-lysine) is a click chemistry reagent containing an azide group .
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- HY-151787
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Azide
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Fmoc-L-Lys(N3-Aca-DIM)-OH is a click chemistry reagent containing an azide group. Used as a SPPS building-block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution .
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- HY-151663
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Fmoc-Abu(3-N3)-OH (2R,3R)
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Azide
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Fmoc-Abu(3-N3) (Fmoc-Abu(3-N3)-OH) (2R,3R) is a click chemistry reagent containing an azide group. Fmoc-Abu(3-N3) (2R,3R) can be used for the research of various biochemical .
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- HY-128676
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H-L-Lys(Poc)-OH hydrochloride
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Alkynes
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N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) hydrochloride is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals . N-ε-propargyloxycarbonyl-L-lysine (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-139014
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H-L-Lys(Poc)-OH
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Alkynes
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N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals . N-ε-propargyloxycarbonyl-L-lysine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-151782
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Azide
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The azide function is widely used for coupling to alkyne-containing fragments via the renowned Click reaction. Polyglycine fragments containing up to 7 glycines are reported to bind to surfaces and have potential application in nanotechnology constructs: constructs of Gly7-NHCH2-fragment containing peptides bind on mica surface in aqueous solution .
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- HY-W190943
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Azide
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Azido-PEG4-Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the cleavable linker Azido-PEG4-Val-Cit-PAB-OH . Azido-PEG4-Val-Cit-PAB-MMAE is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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