T988C (Synonyms: (+)-T988C)

Cat. No.: HY-142102: FAQs
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T988C is a heptacyclic epidithiodioxopiperazine (ETP) natural product. T988C shows strong cytotoxicity to cultured P388 leukemia cells.

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T988C Chemical Structure

CAS No. : 823802-57-9

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Description	T988C is a heptacyclic epidithiodioxopiperazine (ETP) natural product. T988C shows strong cytotoxicity to cultured P388 leukemia cells^[1].
In Vitro	T988C inhibits P388 leukemia cells with an ID₅₀ value of 0.56 μM^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. T988C Related Antibodies
Molecular Weight	480.56
Formula	C₂₃H₂₀N₄O₄S₂
CAS No.	823802-57-9
SMILES	O[C@H]1[C@@]2(C3=CNC4=CC=CC=C34)[C@@](NC5=CC=CC=C52)([H])N6[C@@]17C(N([C@](C6=O)(SS7)CO)C)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (278 KB) Handling Instructions (2659 KB)
References	[1]. DeLorbe JE, et al. General approach for preparing epidithiodioxopiperazines from trioxopiperazine precursors: enantioselective total syntheses of (+)- and (-)-gliocladine C, (+)-leptosin D, (+)-T988C, (+)-bionectin A, and (+)-gliocladin A. J Am Chem Soc. 2013 Mar 13;135(10):4117-28. [Content Brief] [2]. Feng Y, et al. Novel cytotoxic thiodiketopiperazine derivatives from a Tilachlidium sp. J Nat Prod. 2004 Dec;67(12):2090-2. [Content Brief]

T988C Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

T988C823802-57-9(+)-T988COthersInhibitorinhibitorinhibit

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T988C (Synonyms: (+)-T988C)

T988C Related Antibodies

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Biological Activity

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