Search Result
Results for "
Npys
" in MedChemExpress (MCE) Product Catalog:
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W141779
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- HY-P0208
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Neuropeptide Y Receptor
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Neurological Disease
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[Leu31,Pro34]- Neuropeptide Y (porcine), a Neuropeptide Y (NPY) analog, is a selective NPY Y1 receptor agonist. [Leu31,Pro34]- Neuropeptide Y (porcine) exhibits anxiolytic effects .
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- HY-P4123
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HIV
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Others
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TAT (47-57) GGG-Cys(Npys) is a cell-penetrating peptide (CPP). TAT (47-57) GGG-Cys(Npys) has the potential for intracellular drug delivery research .
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- HY-P4103
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- HY-P4101
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HIV
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Infection
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Cys(Npys)-TAT (47-57) is a peptide fragment of TAT peptide and it is able to interact with plasmid DNA electrostatically. Cys(Npys)-TAT (47-57) is corresponding to the transduction domain of TAT with an activated cysteine residue C. TAT is a small nuclear transcriptional activator protein encoded by HIV-1 .
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- HY-P10291
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- HY-101986C
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AR-H 053591 dihydrochloride
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Neuropeptide Y Receptor
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Neurological Disease
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BIIE-0246 dihydrochloride (AR-H 053591 dihydrochloride) is a potent and highly selective non-peptide neuropeptide Y (NPY) Y2 receptor antagonist, with an IC50 value of 15 nM .
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- HY-P2543
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Neuropeptide Y Receptor
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Metabolic Disease
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Neuropeptide Y (3-36) (human, rat), a neuropeptide Y (NPY) metabolite formed from dipeptidyl peptidase-4 (DPP4), is a selective Y2 receptor agonist. Neuropeptide Y (3-36) (human, rat) is a NPY metabolite formed from dipeptidyl peptidase-4 (DPP4). Neuropeptide Y (3-36) (human, rat) decreases release of norepinephrine via the Y2 receptor .
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- HY-116797
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MS0015203
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GPR171
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Metabolic Disease
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MS15203 is a potent and selective GPR171 agonist. MS15203 increases food intake and body weight. MS15203 increases neuronal activity. MS15203 significantly increases the abundance of the mRNAs encoding proSAAS, NPY, AgRP .
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- HY-P1845A
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ERK
EGFR
Reactive Oxygen Species
Calcium Channel
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Neurological Disease
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PACAP-38 (31-38), human, mouse, rat TFA is a PAC1 receptor activator and increases the α-secretase activity. PACAP-38 (31-38), human, mouse, rat TFA elevates cytosolic Ca 2+, increases proliferation and increases phosphorylation of extracellular regulates kinase (ERK) and the epidermal growth factor receptor (EGFR). PACAP-38 (31-38), human, mouse, rat TFA demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production. PACAP-38 (31-38), human, mouse, rat TFA can be used for neurotrophic and neuroprotective research .
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- HY-107730
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Neuropeptide Y Receptor
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Neurological Disease
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NPY5RA-972 is an orally active, central nervous system (CNS) penetrating, potent and selective NPY Y5 receptor antagonist that prevents feeding driven by activation of this receptor .
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- HY-P3676
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Neuropeptide Y Receptor
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Neurological Disease
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Neuropeptide Y (3-36) (porcine) is an agonist of neuropeptide Y (NPY) receptor subtype Y2, and stimulates feeding in rats. Neuropeptide Y (3-36) (porcine) is a highly Y2 selective ligand compared with nselective Y1/Y2 receptor ligand, Neuropeptide Y 1-36 .
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- HY-P1845
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ERK
EGFR
Reactive Oxygen Species
Calcium Channel
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Neurological Disease
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PACAP-38 (31-38), human, mouse, rat is a PAC1 receptor activator and increases the α-secretase activity. PACAP-38 (31-38), human, mouse, rat elevates cytosolic Ca 2+, increases proliferation and increases phosphorylation of extracellular regulates kinase (ERK) and the epidermal growth factor receptor (EGFR). PACAP-38 (31-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production. PACAP-38 (31-38), human, mouse, rat can be used for neurotrophic and neuroprotective research .
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- HY-148179
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- HY-RS09510
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Small Interfering RNA (siRNA)
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Others
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NPY Human Pre-designed siRNA Set A contains three designed siRNAs for NPY gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NPY Human Pre-designed siRNA Set A
NPY Human Pre-designed siRNA Set A
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- HY-107728
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- HY-RS09511
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Small Interfering RNA (siRNA)
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Others
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NPY1R Human Pre-designed siRNA Set A contains three designed siRNAs for NPY1R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NPY1R Human Pre-designed siRNA Set A
NPY1R Human Pre-designed siRNA Set A
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- HY-RS09512
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Small Interfering RNA (siRNA)
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Others
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Npy1r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Npy1r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Npy1r Mouse Pre-designed siRNA Set A
Npy1r Mouse Pre-designed siRNA Set A
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- HY-RS09513
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Small Interfering RNA (siRNA)
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Others
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Npy1r Rat Pre-designed siRNA Set A contains three designed siRNAs for Npy1r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Npy1r Rat Pre-designed siRNA Set A
Npy1r Rat Pre-designed siRNA Set A
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- HY-RS09514
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Small Interfering RNA (siRNA)
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Others
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NPY2R Human Pre-designed siRNA Set A contains three designed siRNAs for NPY2R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NPY2R Human Pre-designed siRNA Set A
NPY2R Human Pre-designed siRNA Set A
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- HY-RS09515
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Small Interfering RNA (siRNA)
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Others
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Npy2r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Npy2r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Npy2r Mouse Pre-designed siRNA Set A
Npy2r Mouse Pre-designed siRNA Set A
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- HY-RS09516
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Small Interfering RNA (siRNA)
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Others
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NPY2R Rat Pre-designed siRNA Set A contains three designed siRNAs for NPY2R gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NPY2R Rat Pre-designed siRNA Set A
NPY2R Rat Pre-designed siRNA Set A
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- HY-RS09517
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Small Interfering RNA (siRNA)
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Others
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NPY4R Human Pre-designed siRNA Set A contains three designed siRNAs for NPY4R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NPY4R Human Pre-designed siRNA Set A
NPY4R Human Pre-designed siRNA Set A
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- HY-RS09518
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Small Interfering RNA (siRNA)
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Others
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Npy4r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Npy4r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Npy4r Mouse Pre-designed siRNA Set A
Npy4r Mouse Pre-designed siRNA Set A
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- HY-RS09519
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Small Interfering RNA (siRNA)
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Others
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Npy4r Rat Pre-designed siRNA Set A contains three designed siRNAs for Npy4r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Npy4r Rat Pre-designed siRNA Set A
Npy4r Rat Pre-designed siRNA Set A
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- HY-RS09520
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Small Interfering RNA (siRNA)
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Others
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NPY5R Human Pre-designed siRNA Set A contains three designed siRNAs for NPY5R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NPY5R Human Pre-designed siRNA Set A
NPY5R Human Pre-designed siRNA Set A
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- HY-RS09521
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Small Interfering RNA (siRNA)
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Others
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Npy5r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Npy5r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Npy5r Mouse Pre-designed siRNA Set A
Npy5r Mouse Pre-designed siRNA Set A
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- HY-RS09522
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Small Interfering RNA (siRNA)
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Others
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Npy5r Rat Pre-designed siRNA Set A contains three designed siRNAs for Npy5r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Npy5r Rat Pre-designed siRNA Set A
Npy5r Rat Pre-designed siRNA Set A
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- HY-P1324
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Neuropeptide Y Receptor
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Neurological Disease
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[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide is a potent and selective neuropeptide Y Y5 receptor agonist with an IC50 of 0.24 nM for binding to the hY5 receptor. [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide induces a high amount of food intake .
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- HY-P1324A
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Neuropeptide Y Receptor
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Neurological Disease
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[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide is a potent and selective neuropeptide Y Y5 receptor agonist with an IC50 of 0.24 nM for binding to the hY5 receptor. [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide induces a high amount of food intake .
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- HY-107734
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Neuropeptide Y Receptor
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Metabolic Disease
Endocrinology
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L 152804 is an orally active and selective neuropeptide Y Y5 receptor (NPY5-R) antagonist, with a Ki of 26 nM for hY5. L 152804 causes weight loss in diet-induced obese mice by modulating food intake and energy expenditure .
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- HY-P1532
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- HY-14423
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- HY-P3678
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Neuropeptide Y Receptor
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Cardiovascular Disease
Neurological Disease
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Neuropeptide Y (18-36) (porcine) is a competitive neuropeptide Y (NPY) cardiac receptor antagonist. Neuropeptide Y (18-36) (porcine) inhibits the binding of I-NPY to cardiac ventricular membranes in a concentration-dependent manner with an IC50 value of 158 nM and an Ki value of 140 nM. Neuropeptide Y (18-36) (porcine) can be used for the research of congestive heart failure .
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- HY-107735
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- HY-101986
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- HY-P1322
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Neuropeptide Y Receptor
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Neurological Disease
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[D-Trp34]-Neuropeptide Y is a potent and selective neuropeptide Y (NPY) Y5 receptor agonist. [D-Trp34]-Neuropeptide Y is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6 receptors. [D-Trp34]-Neuropeptide Y markedly increases food intake in rats .
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- HY-107733
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- HY-P1322A
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Neuropeptide Y Receptor
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Neurological Disease
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[D-Trp34]-Neuropeptide Y TFA is a potent and selective neuropeptide Y (NPY) Y5 receptor agonist. [D-Trp34]-Neuropeptide Y TFA is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6 receptors. [D-Trp34]-Neuropeptide Y TFA markedly increases food intake in rats .
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- HY-101986A
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AR-H 053591 hydrochloride
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Neuropeptide Y Receptor
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Metabolic Disease
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BIIE-0246 hydrochloride (AR-H 053591 hydrochloride) is a potent and selective NPY2R (neuropeptide Y receptor 2) antagonist with an IC50 value of 15 nM for rat [ 125I]PYY3-36. BIIE-0246 hydrochloride decreases the expression of p-AKT S473, P-p44/42 MAPK under the NPY-stimulated. BIIE-0246 hydrochloride reduces albuminuria in ADR nephropathy .
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- HY-110107
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- HY-P0199
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- HY-P1817
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PACAP Receptor
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Neurological Disease
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PACAP-38 (16-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production . PACAP is a potent activator of cAMP formation .
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- HY-P10000
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Neuropeptide Y Receptor
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Metabolic Disease
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Peptide YY (PYY) (3-36), Human is an endogenous appetite suppressing peptide. Peptide YY (PYY) (3-36), Human, a neuropeptide Y (NPY) Y2 receptor agonist, is a powerful inhibitor of intestinal secretion .
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- HY-P1537
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Neuropeptide Y Receptor
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Metabolic Disease
Endocrinology
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Pancreatic Polypeptide, bovine, a 36-amino acid, straight chain polypeptide derived primarily from the pancreas, inhibits secretin- and cholecystokinin-stimulated pancreatic secretion; Pancreatic Polypeptide, bovine acts as an agonist of NPY receptor, with high affinity at NPYR4.
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- HY-107725
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Neuropeptide Y Receptor
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Metabolic Disease
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BIBO3304 TFA is a potent, orally active, and selective neuropeptide Y (NPY) Y1 receptor antagonist, with subnanomolar affinity for both the human and the rat Y1 receptor (IC50=0.38 and 0.72 nM, respectively) .
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- HY-P3679
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Neuropeptide Y Receptor
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Neuropeptide Y (1-24) (human) is a neuropeptide with potencies in inhibiting the electricity stimulated twitch response of rat vas deferens. Neuropeptide Y (1-24) (human) stimulates N-methyl-D-aspartate (NMDA)-induced neuronal activation in the rat CA3 region of the dorsal hippocampus in vivo .
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- HY-107565
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Others
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Inflammation/Immunology
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2-Pyridylethylamine is a histamine-1 (H1R) receptor agonist. 2-Pyridylethylamine can reduce the joint injury induced by formalin in rats. 2-Pyridylethylamine can be used to study the spinal cord release of neuropeptide (NPY) .
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- HY-P0198B
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- HY-107726A
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Neuropeptide Y Receptor
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Neurological Disease
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BIBP3226 is a potent and selective neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist, with Kis of 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF, respectively. BIBP3226 displays anxiogenic-like effect .
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- HY-107726
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Neuropeptide Y Receptor
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Neurological Disease
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BIBP3226 TFA is a potent and selective neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist, with Kis of 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF, respectively. BIBP3226 TFA displays anxiogenic-like effect .
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- HY-107725A
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Neuropeptide Y Receptor
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Metabolic Disease
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BIBO3304 (diTFA) is an orally effective and selective neuropeptide Y (NPY) Y1 receptor antagonist. BIBO3304 (diTFA) has a high affinity for both human and rat Y1 receptors, with IC50 values of 0.38 and 0.72 nM, respectively. BIBO3304 (diTFA) promotes bone-tendon healing through the Wnt/β-catenin signaling pathway .
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- HY-103247
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Angiotensin Receptor
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Cardiovascular Disease
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EMD 66684 is an antagonist of Angiotensin II Type 1 (AT1) receptor. EMD 66684 shows potent binding affinities for the AT1 subtype Ang II receptor with an IC50 value of 0.7 nM. EMD 66684 also serves as an antiischemic cytoprotectant - .
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Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P4137
-
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Peptides
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Others
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Cys(Npys) Antennapedia Peptide, amide is a peptide. Cys(Npys) Antennapedia Peptide, amide can be used for various biochemical studies .
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- HY-P4087
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Peptides
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Others
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Cys(Npys)-(Arg)9 is a cell penetrating peptide. Cys(Npys)-(Arg)9 is comprised of 9 D-Arginine residues and an activated cysteine residue C(Npys). Cys(Npys)-(Arg)9 can be used as a carrier peptide applicable in conjugation and cell permable studies .
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- HY-P4123
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HIV
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Others
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TAT (47-57) GGG-Cys(Npys) is a cell-penetrating peptide (CPP). TAT (47-57) GGG-Cys(Npys) has the potential for intracellular drug delivery research .
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- HY-P4099
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Peptides
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Others
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Cys(Npys)-(D-Arg)9 is an amphipathic R9 cell penetrating peptide (CPP). Cys(Npys)-(D-Arg)9 has cytotoxicity for microspore cells with the amount higher than 1 nmol .
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- HY-P4103
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- HY-P4101
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HIV
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Infection
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Cys(Npys)-TAT (47-57) is a peptide fragment of TAT peptide and it is able to interact with plasmid DNA electrostatically. Cys(Npys)-TAT (47-57) is corresponding to the transduction domain of TAT with an activated cysteine residue C. TAT is a small nuclear transcriptional activator protein encoded by HIV-1 .
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- HY-P4316
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Peptides
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Others
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Cys(NPys)-D{Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg}-NH2 is a cell-penetrating polypeptide composed of nine arginines and cysteines, used to carry therapeutic agent into the cell .
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- HY-W141779
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- HY-P0208
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Neuropeptide Y Receptor
|
Neurological Disease
|
[Leu31,Pro34]- Neuropeptide Y (porcine), a Neuropeptide Y (NPY) analog, is a selective NPY Y1 receptor agonist. [Leu31,Pro34]- Neuropeptide Y (porcine) exhibits anxiolytic effects .
|
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- HY-P10291
-
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- HY-P2543
-
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Neuropeptide Y Receptor
|
Metabolic Disease
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Neuropeptide Y (3-36) (human, rat), a neuropeptide Y (NPY) metabolite formed from dipeptidyl peptidase-4 (DPP4), is a selective Y2 receptor agonist. Neuropeptide Y (3-36) (human, rat) is a NPY metabolite formed from dipeptidyl peptidase-4 (DPP4). Neuropeptide Y (3-36) (human, rat) decreases release of norepinephrine via the Y2 receptor .
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- HY-P1845A
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ERK
EGFR
Reactive Oxygen Species
Calcium Channel
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Neurological Disease
|
PACAP-38 (31-38), human, mouse, rat TFA is a PAC1 receptor activator and increases the α-secretase activity. PACAP-38 (31-38), human, mouse, rat TFA elevates cytosolic Ca 2+, increases proliferation and increases phosphorylation of extracellular regulates kinase (ERK) and the epidermal growth factor receptor (EGFR). PACAP-38 (31-38), human, mouse, rat TFA demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production. PACAP-38 (31-38), human, mouse, rat TFA can be used for neurotrophic and neuroprotective research .
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- HY-P3676
-
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Neuropeptide Y Receptor
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Neurological Disease
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Neuropeptide Y (3-36) (porcine) is an agonist of neuropeptide Y (NPY) receptor subtype Y2, and stimulates feeding in rats. Neuropeptide Y (3-36) (porcine) is a highly Y2 selective ligand compared with nselective Y1/Y2 receptor ligand, Neuropeptide Y 1-36 .
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- HY-P1845
-
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ERK
EGFR
Reactive Oxygen Species
Calcium Channel
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Neurological Disease
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PACAP-38 (31-38), human, mouse, rat is a PAC1 receptor activator and increases the α-secretase activity. PACAP-38 (31-38), human, mouse, rat elevates cytosolic Ca 2+, increases proliferation and increases phosphorylation of extracellular regulates kinase (ERK) and the epidermal growth factor receptor (EGFR). PACAP-38 (31-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production. PACAP-38 (31-38), human, mouse, rat can be used for neurotrophic and neuroprotective research .
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- HY-P1324
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Neuropeptide Y Receptor
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Neurological Disease
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[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide is a potent and selective neuropeptide Y Y5 receptor agonist with an IC50 of 0.24 nM for binding to the hY5 receptor. [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide induces a high amount of food intake .
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- HY-P1324A
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Neuropeptide Y Receptor
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Neurological Disease
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[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide is a potent and selective neuropeptide Y Y5 receptor agonist with an IC50 of 0.24 nM for binding to the hY5 receptor. [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide induces a high amount of food intake .
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- HY-P1532
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- HY-P3678
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Neuropeptide Y Receptor
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Cardiovascular Disease
Neurological Disease
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Neuropeptide Y (18-36) (porcine) is a competitive neuropeptide Y (NPY) cardiac receptor antagonist. Neuropeptide Y (18-36) (porcine) inhibits the binding of I-NPY to cardiac ventricular membranes in a concentration-dependent manner with an IC50 value of 158 nM and an Ki value of 140 nM. Neuropeptide Y (18-36) (porcine) can be used for the research of congestive heart failure .
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- HY-P1322
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Neuropeptide Y Receptor
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Neurological Disease
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[D-Trp34]-Neuropeptide Y is a potent and selective neuropeptide Y (NPY) Y5 receptor agonist. [D-Trp34]-Neuropeptide Y is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6 receptors. [D-Trp34]-Neuropeptide Y markedly increases food intake in rats .
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- HY-P1322A
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Neuropeptide Y Receptor
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Neurological Disease
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[D-Trp34]-Neuropeptide Y TFA is a potent and selective neuropeptide Y (NPY) Y5 receptor agonist. [D-Trp34]-Neuropeptide Y TFA is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6 receptors. [D-Trp34]-Neuropeptide Y TFA markedly increases food intake in rats .
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- HY-P0199
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- HY-P1817
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PACAP Receptor
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Neurological Disease
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PACAP-38 (16-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production . PACAP is a potent activator of cAMP formation .
|
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- HY-P10000
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Neuropeptide Y Receptor
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Metabolic Disease
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Peptide YY (PYY) (3-36), Human is an endogenous appetite suppressing peptide. Peptide YY (PYY) (3-36), Human, a neuropeptide Y (NPY) Y2 receptor agonist, is a powerful inhibitor of intestinal secretion .
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- HY-P1537
-
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Neuropeptide Y Receptor
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Metabolic Disease
Endocrinology
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Pancreatic Polypeptide, bovine, a 36-amino acid, straight chain polypeptide derived primarily from the pancreas, inhibits secretin- and cholecystokinin-stimulated pancreatic secretion; Pancreatic Polypeptide, bovine acts as an agonist of NPY receptor, with high affinity at NPYR4.
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- HY-P3679
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Neuropeptide Y Receptor
|
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Neuropeptide Y (1-24) (human) is a neuropeptide with potencies in inhibiting the electricity stimulated twitch response of rat vas deferens. Neuropeptide Y (1-24) (human) stimulates N-methyl-D-aspartate (NMDA)-induced neuronal activation in the rat CA3 region of the dorsal hippocampus in vivo .
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- HY-P0198B
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