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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D1056
    Lipopolysaccharides, from E. coli O55:B5
    Maximum Cited Publications
    161 Publications Verification

    LPS, from Escherichia coli (O55:B5)

    Toll-like Receptor (TLR) Inflammation/Immunology
    Lipopolysaccharides (LPS) is an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consists of an antigen O-specific chain, a core oligosaccharide and lipid A. Lipopolysaccharides is a pathogenic associated molecular pattern (PAMP) that activates the immune system. Lipopolysaccharides activates TLR-4 on immune cells . This product is derived from Escherichia coli O55:B5. Lipopolysaccharides induces secretion of cell migrasome .
    Lipopolysaccharides, from E. <em>coli</em> O55:B5
  • HY-P2733

    GPO

    Endogenous Metabolite Metabolic Disease
    Glycerol-3-phosphate oxidase, E. coli (GPO) is a key intermediate in glycerol metabolism. Glycerol-3-phosphate oxidase can be extracted from Escherichia coli. Glycerol-3-phosphate oxidase is the skeleton of phospholipids in membrane lipids, and also the substrate of respiratory chain. Glycerol-3-phosphate oxidase produces electrons through oxidation .
    Glycerol-3-phosphate oxidase, E. <em>coli</em>
  • HY-155048

    Bacterial Infection
    BDM91270 (compound 29) is an E. coli AcrAB-TolC efflux pump inhibitor with an EC90 of 0.6 μM for wild-type E. coli AcrB. BDM91270 can be used in the study of Escherichia coli drug resistance .
    BDM91270
  • HY-157351

    Biochemical Assay Reagents Others
    E.Coli Broth is a selectively concentrated broth that can be used to isolate, detect or culture E. coli.
    E.<em>Coli</em> Broth
  • HY-NP025

    EPEC

    Bacterial Infection
    E.coli Bacterial protein is a native protein that can be isolated from E.coli .
    E.<em>coli</em> Bacterial protein
  • HY-148197

    Endogenous Metabolite Others
    Glutathionylspermidine is a peptide and a metabolite of E. coli .
    Glutathionylspermidine
  • HY-142080

    Bacterial Infection
    Pimeloyl-CoA is a biotin precursor of Escherichia coli. Pimeloyl-CoA can be used for the research of the pathway of de novo biotin biosynthesis in Escherichia coli .
    Pimeloyl-CoA
  • HY-156859A

    Bacterial Infection
    NSC309401 is an inhibitor of E. coli DHFR (IC50: 189 nM, KD: 14.57 nM) .
    NSC309401
  • HY-E70284

    Biochemical Assay Reagents Others
    Keratanase II,bacillus circulans,expressed in E.coli has transglycosylation activity. Keratanase II,bacillus circulans,expressed in E.coli efficiently catalyzes the transglycosylation of α(2→3)-sialylated 6,6′-di-sulfo-LacNAc with two kinds of glycosyl acceptors, 6-sulfo-Lewis X and 6,6'-di-sulfo-LacNAc derivatives, providing Sialyl sulfo-hexasaccharide and Sialyl sulfo-pentasaccharide .
    Keratanase II,bacillus circulans,expressed in E.<em>coli</em>
  • HY-133154

    CAIR; 4-Carboxy-AIR

    Endogenous Metabolite Infection
    Carboxyaminoimidazole ribotide (CAIR) is a metabolite of E. coli. Carboxyaminoimidazole ribotide can be used to detect distinctive features of E. coli PurE active site and synthesis fungal de novo purine .
    Carboxyaminoimidazole ribotide
  • HY-P2869B

    Others Metabolic Disease
    β1-4 Galactosidase, E. coli is a highly specific exoglycosidase that catalyzes the hydrolysis of terminal, non-reducing β1-4 linked galactose residues from oligosaccharides .
    β1-4 Galactosidase, E. <em>coli</em>
  • HY-146400

    Bacterial Infection
    Antibacterial agent 97 (hit compound) is a potent antibacterial agent. Antibacterial agent 97 shows antibacterial activities with MIC of 16 and 16 µg/mL for Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), respectively .
    Antibacterial agent 97
  • HY-142545

    Bacterial Infection
    Antibacterial agent 68 (compound 4d) is an antibacterial agent against drug-resistant Escherichia coli. Antibacterial agent 68 has low cytotoxicity and exerts strong antibacterial activities against multidrug-resistant Escherichia coli at low concentrations as 0.007 mM .
    Antibacterial agent 68
  • HY-N12287

    Pilosidine

    Bacterial Inflammation/Immunology
    Curcapicycloside (Pilosidine), a norlignan glucoside, exhibits antibacterial activity against Escherichia coli .
    Curcapicycloside
  • HY-147381

    Others Others
    MetRS-IN-1 (Compound 27) is an E. coli methionyl-tRNA synthetase (MetRS) inhibitor (IC50=237 nM) .
    MetRS-IN-1
  • HY-118211

    Others Infection
    EcDsbB-IN-9 (Compound 9) is a potent E. coli DsbB (EcDsbB) inhibitor with an IC50 of 1.7 μM and a Ki of 46 nM .
    EcDsbB-IN-9
  • HY-P5624

    Bacterial Infection
    Gallin is an antimicrobial peptide derived from egg whites. Gallin inhibits the growth of Escherischia coli at 0.25 μM concentration .
    Gallin
  • HY-W001941

    Others Others
    D-Cystine is the D-enantiomer of L-Cystine. D-Cystine inhibits L-aspartate-β-semialdehyde dehydrogenase (ASADH) from Escherichia coli .
    D-Cystine
  • HY-N7322

    Bacterial Infection
    Swietemahalactone is a natural compound isolated from Swietenia mahagoni. Swietemahalactone exhibits antibacterial activity aganist E. coli .
    Swietemahalactone
  • HY-118827

    Quadrisol; CERM 10202; PM 150

    COX Inflammation/Immunology
    Vedaprofen (Quadrisol) is a COX-1 selective nonsteroidal anti-inflammatory agent (NSAID) for serum TxB2 and exudate PGE2 inhibition . Vedaprofen is a Escherichia coli (E. coli) sliding clamp (SC) inhibitor with the IC50 of 222 μM .
    Vedaprofen
  • HY-W009912

    Amino Acid Derivatives Others
    H-Tyr(Me)-OH is a synthetic amino acid, and can enter into protein in E. coli in response to an amber nonsense codon .
    H-Tyr(Me)-OH
  • HY-149679

    PROTACs Bacterial Cancer
    PROTAC eDHFR Degrader-2 (compound 7b) is a potent degrader targeting Escherichia coli dihydrofolate reductase (eDHFR), enabling robust degradation of eDHFR-tagged proteins .
    PROTAC eDHFR Degrader-2
  • HY-139747

    Bacterial Infection
    Antibacterial agent 32 (example 43) is an antibacterial agent with MIC values of 1 mcg/mL, 2 mcg/mL, and 8 mcg/mL against E. coli strains NCTC 13351, M 50 and 7 MP, respectively (WO2013030733A1) .
    Antibacterial agent 32
  • HY-139767

    Bacterial Infection
    Antibacterial agent 50 (example 47) is an antibacterial agent with MIC values of 32 mcg/mL, 64 mcg/mL, and 128 mcg/mL against E. coli strains NCTC 13351, M 50 and 7 MP, respectively (WO2013030733A1) .
    Antibacterial agent 50
  • HY-139768

    Bacterial Infection
    Antibacterial agent 51 (example 45) is an antibacterial agent with MIC values of 4 mcg/mL, 8 mcg/mL, and 8 mcg/mL against E. coli strains NCTC 13351, M 50 and 7 MP, respectively (WO2013030733A1) .
    Antibacterial agent 51
  • HY-D2277

    Fluorescent Dye Others
    Fluorescein-CM2 is a fluorogenic molecule that can be used to rapidly screen esterase cut sites for protein-protein interaction-dependent (PPI-dependent) esterase activity in E. coli .
    Fluorescein-CM2
  • HY-P10257

    Bacterial Infection
    KR-12 human is an active segment of LL-37, which exhibits antimicrobial activity against gram-negative bacteria. KR-12 human inhibits E. coli K-12 with MIC of 66 μM .
    KR-12 (human)
  • HY-N8300

    Bacterial Infection
    Rupesin E is a natural product that can be isolated from Patrinia rupestris. Rupesin E has significant antibacterial activity against Escherichia coli .
    Rupesin E
  • HY-119543

    Amino Acid Derivatives Others
    O-Succinyl-L-homoserine is a homoserine derivative. O-Succinyl-L-homoserine is an intermediate in the biosynthesis of methionine in Escherichia coli and Salmonella typhimurium .
    O-Succinyl-L-homoserine
  • HY-W109754

    2',4'-DHC

    Bacterial Infection
    2',4'-Dihydroxychalcone, in combination with nalidixic acid (HY-B0398), exhibits synergistic effects against E. coli by reducing membrane permeability .
    2',4'-Dihydroxylchalcone
  • HY-N8515C

    UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine disodium

    Endogenous Metabolite Infection Others
    UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine) disodium is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .
    UDP-3-O-acyl-GlcNAc disodium
  • HY-130281

    Bacterial Inflammation/Immunology
    Ianthelliformisamine B diTFA is a bromotyrosine-derived antibacterial agent. Ianthelliformisamine B diTFA is against E. coli and S. aureus strains with MICs of 14.5 μM and 144.7 μM .
    Ianthelliformisamine B diTFA
  • HY-109591

    Biochemical Assay Reagents Others
    Oleoyl coenzyme A (Oleoyl-CoA) is a thioester of oleic acid and coenzyme A. Oleoyl coenzyme A has a role as an Escherichia coli metabolite and a mouse metabolite .
    Oleoyl Coenzyme A
  • HY-15935B

    Fluorescent Dye Others
    X-Gluc cyclohexanamine is a dye reagent for the detection of β-glucuronidase (GUS), an enzyme produced by E. coli. X-Gluc cyclohexanamine can be used to detect E. coli contamination in food, water and the urinary tract (GUS as a specific detection indicator). X-Gluc cyclohexanamine is also widely used in molecular biology experiments to label and detect the expression of target genes (reacts with the GUS gene, appears blue) .
    X-Gluc cyclohexanamine
  • HY-144019

    Liposome Infection
    18:0 EPC chloride is a synthetic cationic phospholipid. 18:0 EPC chloride (at the critical synergistic concentrations of 2.34-2.93 μM) significantly improves the inactivation effect of eugenol against Escherichia coli .
    18:0 EPC chloride
  • HY-139746

    Beta-lactamase Bacterial Infection
    FPI-1602 is a β-lactamase inhibitor. FPI-1602 displays marked antimicrobial activity against P. aeruginosa, E. coli, and Enterobacter spp. .
    FPI-1602
  • HY-15935

    Fluorescent Dye Others
    X-Gluc Dicyclohexylamine is a dye reagent for the detection of β-glucuronidase, an enzyme produced by Escherichia coli. X-Gluc sodium can be used to detect E. coli contamination in food, water and the urinary tract. X-Gluc sodium is also widely used in molecular biology experiments to label and detect the expression of target genes (GUS reporter system) .
    X-Gluc Dicyclohexylamine
  • HY-120382

    Bacterial Infection
    LY 215890 ia an orally active antibacterial agent aganist Escherichia coli EC14 and Klebsiella pneumonia X26 .
    LY 215890
  • HY-109591A

    Oleoyl-CoA lithium

    Biochemical Assay Reagents Others
    Oleoyl coenzyme A (Oleoyl-CoA) lithium is a thioester of oleic acid and coenzyme A. Oleoyl coenzyme A lithium has a role as an Escherichia coli metabolite and a mouse metabolite .
    Oleoyl coenzyme A lithium
  • HY-A0155

    Antibiotic Bacterial Cancer
    Viomycin is a potent antibiotic against Mycobacteria. Viomycin rapidly inhibits polypeptide chain elongation when added to purified endogenous Escherichia coli polysomes actively engaged in polypeptide synthesis .
    Viomycin
  • HY-P2869

    EC 3.2.1.23; GAL

    Endogenous Metabolite Others
    β-Galactosidase (EC 3.2.1.23) is a glycoside hydrolase that hydrolyzes the β-glycosidic bonds formed between galactose and its organic moieties. In E.coli, the lacZ gene is the structural gene of β-galactosidase, which can be used as part of the induction system lac operon. β-Galactosidase can hydrolyze lactose to form glucose and galactose, and enter glycolysis; it can also catalyze the transgalactosylation of lactose into allolactose; allolactose can be cracked into monosaccharides .
    β-Galactosidase, E. <em>coli</em>
  • HY-P2145

    EDF

    Bacterial Infection
    Extracellular death factor (EDF) is the only single signaling molecule involved in Escherichia coli quorum sensing, and can initiate MAZEF-mediated cell death. Extracellular death factor significantly amplifies the endoribonucleolytic activities of both MazF and ChpBK .
    Extracellular death factor
  • HY-163383

    L-EOP

    Bacterial Infection
    L-Ent-oxPt IV (L-EOP) is a Oxaliplatin (HY-17371)-based siderophore-platinum conjugate. L-Ent-oxPt IV exhibits selectivity towards Escherichia coli and antibacterial activity through DNA damage .
    L-Ent-oxPt(IV)
  • HY-144281

    Bacterial Infection
    MsbA-IN-3 (compound 31) is a potent and highly selective MsbA inhibitor with an IC50 value of 2 nM. MsbA-IN-3 has inhibitory activity against Escherichia coli with a MIC of 35 μM .
    MsbA-IN-3
  • HY-144282

    Bacterial Infection
    MsbA-IN-4 (compound 32) is a potent and highly selective MsbA inhibitor with an IC50 value of 3 nM. MsbA-IN-4 has inhibitory activity against Escherichia coli with a MIC of 12 μM .
    MsbA-IN-4
  • HY-15935C

    Fluorescent Dye Others
    X-Gluc sodium is a dye reagent for the detection of β-glucuronidase (GUS), an enzyme produced by E. coli. X-Gluc sodium can be used to detect E. coli contamination in food, water and the urinary tract (GUS as a specific detection indicator). X-Gluc sodium is also widely used in molecular biology experiments to label and detect the expression of target genes (reacts with the GUS gene, appears blue) .
    X-Gluc sodium
  • HY-P5670

    Bacterial Infection
    Maximin 31 is an antimicrobial peptide derived from the toad brain. Maximin 31 is active against Staphylococcus aureus and Escherichia coli, with MIC values of 37.5, 75 μg/mL, respectively .
    Maximin 31
  • HY-W142014

    Thymidylate Synthase Cancer
    N,O-Didansyl-L-tyrosine cyclohexylammonium is a potent selective thymidylate synthase (TS) inhibitor, acts on TS of Escherichia coli, Lactobacillus casei and human with the IC50 values of 5.0, 3.4 and 119 μM, respectively .
    N,O-Didansyl-L-tyrosine cyclohexylammonium
  • HY-P5671

    Bacterial Infection
    Maximin 32 is an antimicrobial peptide derived from the toad brain. Maximin 32 is active against Staphylococcus aureus and Escherichia coli, with MIC values of 9.4, 18.8 μg/mL, respectively .
    Maximin 32
  • HY-P5672

    Bacterial Infection
    Maximin 39 is an antimicrobial peptide derived from the toad brain. Maximin 39 is active against Staphylococcus aureus and Escherichia coli, with MIC values of 18.8, 37.5 μg/mL, respectively .
    Maximin 39

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