HY-14768 T 705 (Synonyms Favipiravir; T-705) |
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T 705 Technical Data:
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Price and Availability of T 705 |
T 705 M.Wt: 157.1
T 705 Formula: C5H4FN3O2
T 705 Purity: >98
T 705 Storage: at -20℃ 2 years
T 705 CAS No.: 259793-96-9
T 705 Solubility: DMSO
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| USD |
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| 5mg/$110 |
In-stock
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| 10mg/$165 |
In-stock
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| 50mg/$715 |
In-stock
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| 200mg/$2200 |
In-stock
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| >1000mg |
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We offer a substantial discount on larger orders,please
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or Fax: 609-228-5909
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T 705 Data Sheet: |
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Biological Activity of T 705:
T 705(Favipiravir) is a RNA-directed RNA polymerase NS5B inhibitor.T 705(Favipiravir) is useful for Antiviral agents. |
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References on T 705:
[1]. Favipiravir: RNA-directed RNA polymerase NS5B inhibitor treatment of influenza A By Reviriego, C.From Drugs of the Future (2010), 35(9), 713-717.
Abstract
Here we report a comprehensive biological characterization of a potent and selective small-molecule inhibitor of the DNA damage response (DDR) kinase ATR. We show a profound synthetic lethal interaction between ATR and the ATM-p53 tumor suppressor pathway in cells treated with DNA-damaging agents and establish ATR inhibition as a way to transform the outcome for patients with cancer treated with ionizing radiation or genotoxic drugs.
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