1. Membrane Transporter/Ion Channel
  2. CFTR

VX-661 (Synonyms: Tezacaftor)

Cat. No.: HY-15448 Purity: 99.56%
Data Sheet SDS Handling Instructions

VX-661 is a second F508del CFTR corrector and help CFTR protein reach the cell surface.

For research use only. We do not sell to patients.
VX-661 Chemical Structure

VX-661 Chemical Structure

CAS No. : 1152311-62-0

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO $103 In-stock
5 mg $90 In-stock
10 mg $140 In-stock
50 mg $400 In-stock
100 mg $590 In-stock
200 mg $950 In-stock
500 mg   Get quote  
1 g   Get quote  

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Description

VX-661 is a second F508del CFTR corrector and help CFTR protein reach the cell surface.

In Vitro

In vitro, a combination of VX-661 and ivacaftor results in greater CFTR activity compared with VX-661 alone[2].

Clinical Trial
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References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 1.9212 mL 9.6061 mL 19.2123 mL
5 mM 0.3842 mL 1.9212 mL 3.8425 mL
10 mM 0.1921 mL 0.9606 mL 1.9212 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

520.5

Formula

C₂₆H₂₇F₃N₂O₆

CAS No.

1152311-62-0

Storage

4°C, stored under nitrogen

Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

Purity: 99.56%

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VX-661
Cat. No.:
HY-15448
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