[Des-Arg9]-Bradykinin

Cat. No.: HY-P0298: FAQs
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[Des-Arg9]-Bradykinin is a Bradykinin (B₁) receptor agonist that displays selectivity for B₁ over B₂ receptors.

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[Des-Arg9]-Bradykinin Chemical Structure

CAS No. : 15958-92-6

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Other In-stock Forms of [Des-Arg9]-Bradykinin:

[Des-Arg9]-Bradykinin acetate

Other Forms of [Des-Arg9]-Bradykinin:

[Des-Arg9]-Bradykinin acetate In-stock

1 Publications Citing Use of MCE [Des-Arg9]-Bradykinin

•Nat Commun. 2023 Sep 21;14(1):5891. [Abstract]

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Description	[Des-Arg9]-Bradykinin is a Bradykinin (B₁) receptor agonist that displays selectivity for B₁ over B₂ receptors.
IC₅₀ & Target	Bradykinin (B₁) receptor^[1]
In Vitro	The B₂ receptor mediates the action of bradykinin (BK) and lysyl-bradykinin (Lys-BK), the first set of bioactive kinins formed in response to injury from kininogen precursors through the actions of plasma and tissue kallikreins, whereas the B₁ receptor mediates the action of [Des-Arg⁹]-Bradykinin (des-Arg⁹-BK) and Lys-des-Arg Arg⁹-BK, the second set of bioactive kinins formed through the actions of carboxypeptidases on BK and Lys-BK, respectively^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. [Des-Arg9]-Bradykinin Related Antibodies
Molecular Weight	904.02
Formula	C₄₄H₆₁N₁₁O₁₀
CAS No.	15958-92-6
Sequence	Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe
Sequence Shortening	RPPGFSPF
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (258 KB) Handling Instructions (2659 KB)
References	[1]. Leeb-Lundberg LM, et al. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev. 2005 Mar;57(1):27-77. [Content Brief]

[Des-Arg9]-Bradykinin Related Classifications

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

[Des-Arg9]-Bradykinin15958-92-6Bradykinin ReceptorInhibitorinhibitorinhibit

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