2. Cell Cycle/DNA Damage
  3. DNA Alkylator/Crosslinker
  4. 2-Iodoacetamide-d4

2-Iodoacetamide-d4  (Synonyms: Iodoacetamide-d4)

Cat. No.: HY-34477S1
COA Handling Instructions

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2-Iodoacetamide-d4 is the deuterium labeled 2-Iodoacetamide[1]. 2-Iodoacetamide (Iodoacetamide), an alkylating agent, is a commonly used agent for alkylation of cysteine during sample preparation for proteomics[2][3].

For research use only. We do not sell to patients.

2-Iodoacetamide-d<sub>4</sub> Chemical Structure

2-Iodoacetamide-d4 Chemical Structure

CAS No. : 1219802-64-8

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5 mg USD 130 In-stock
10 mg USD 210 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of 2-Iodoacetamide-d4:

2-Iodoacetamide-d4 Related Antibodies

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Description

2-Iodoacetamide-d4 is the deuterium labeled 2-Iodoacetamide[1]. 2-Iodoacetamide (Iodoacetamide), an alkylating agent, is a commonly used agent for alkylation of cysteine during sample preparation for proteomics[2][3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2-Iodoacetamide-d4 Related Antibodies
Molecular Weight

188.99

Formula

C2D4INO
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

IC([2H])([2H])C(N([2H])[2H])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (529.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.2913 mL 26.4564 mL 52.9128 mL
5 mM 1.0583 mL 5.2913 mL 10.5826 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.2913 mL 26.4564 mL 52.9129 mL 132.2821 mL
5 mM 1.0583 mL 5.2913 mL 10.5826 mL 26.4564 mL
10 mM 0.5291 mL 2.6456 mL 5.2913 mL 13.2282 mL
15 mM 0.3528 mL 1.7638 mL 3.5275 mL 8.8188 mL
20 mM 0.2646 mL 1.3228 mL 2.6456 mL 6.6141 mL
25 mM 0.2117 mL 1.0583 mL 2.1165 mL 5.2913 mL
30 mM 0.1764 mL 0.8819 mL 1.7638 mL 4.4094 mL
40 mM 0.1323 mL 0.6614 mL 1.3228 mL 3.3071 mL
50 mM 0.1058 mL 0.5291 mL 1.0583 mL 2.6456 mL
60 mM 0.0882 mL 0.4409 mL 0.8819 mL 2.2047 mL
80 mM 0.0661 mL 0.3307 mL 0.6614 mL 1.6535 mL
100 mM 0.0529 mL 0.2646 mL 0.5291 mL 1.3228 mL
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2-Iodoacetamide-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-Iodoacetamide-d41219802-64-8Iodoacetamide-d4DNA Alkylator/CrosslinkerInhibitorinhibitorinhibit

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