2. (24E)-3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid

(24E)-3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid 

Cat. No.: HY-N1783
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(24E)-3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid is a potent PTP1B inhibitor, with an IC50 of 0.4 μM. (24E)-3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid exhibits potent PTP1B inhibitory activity without cytotoxicity.

For research use only. We do not sell to patients.

(24E)-3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid Chemical Structure

(24E)-3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid Chemical Structure

CAS No. : 329975-47-5

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(24E)-3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid Related Antibodies

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Description

(24E)-3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid is a potent PTP1B inhibitor, with an IC50 of 0.4 μM. (24E)-3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid exhibits potent PTP1B inhibitory activity without cytotoxicity[1].

IC50 & Target

IC50: 0.4 μM (PTP1B)[1]
In Vitro

(24E)-3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid has little growth inhibitory effects against human cancer cell lines Huh-7 (hepatoma) and EJ-1 (bladder), up to 50 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(24E)-3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid Related Antibodies
Molecular Weight

516.71

Formula

C31H48O6
CAS No.
SMILES

O=C(O)CC[C@@H]([C@@]1(C)[C@]2([H])[C@]3(C)CC[C@@]([C@H](C)CC/C=C(C(O)=O)\C)(C)[C@@]3(C)CC1)/C(CC2)=C(C(O)=O)\C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(24E)-3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid329975-47-5Inhibitorinhibitorinhibit

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