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  3. Disease Research Fields Plants Alkaloids Phenols
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  5. Laurolitsine hydrochloride

Laurolitsine hydrochloride  (Synonyms: (+)-Norboldine hydrochloride)

Cat. No.: HY-N2352A Purity: 99.81%
COA Handling Instructions

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Laurolitsine hydrochloride is an alkaloid isolated from Phoebe formosana, and shows weak anti-inflammatory activity.

For research use only. We do not sell to patients.

Laurolitsine hydrochloride Chemical Structure

Laurolitsine hydrochloride Chemical Structure

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 480 In-stock
Solution
10 mM * 1 mL in DMSO USD 480 In-stock
Solid
1 mg USD 180 In-stock
5 mg USD 624 In-stock
10 mg USD 1104 In-stock
50 mg   Get quote  
100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Laurolitsine hydrochloride:

Laurolitsine hydrochloride Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Laurolitsine hydrochloride is an alkaloid isolated from Phoebe formosana, and shows weak anti-inflammatory activity.

In Vitro

Laurolitsine shows weak anti-inflammatory activity against NO production in RAW 267.4 and BV-2 cells[1]. Boldine, laurolitsine and litebamine (300 μM) remarkedly inhibit the aggregation of rabbit platelets induced by arachidonic acid (100 μM) and collagen (10 μM/mL), and slightly inhibit that induced by ADP (20 μM)[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Laurolitsine hydrochloride Related Antibodies
Molecular Weight

349.81

Formula

C18H20ClNO4
Appearance

Solid

Color

White to pink

SMILES

OC1=C(OC)C2=C3C(CCN[C@@]3([H])CC4=CC(O)=C(OC)C=C24)=C1.[H]Cl
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 83 mg/mL (237.27 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8587 mL 14.2935 mL 28.5869 mL
5 mM 0.5717 mL 2.8587 mL 5.7174 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.81%

COA (255 KB) HNMR (299 KB) LCMS (321 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8587 mL 14.2935 mL 28.5869 mL 71.4674 mL
5 mM 0.5717 mL 2.8587 mL 5.7174 mL 14.2935 mL
10 mM 0.2859 mL 1.4293 mL 2.8587 mL 7.1467 mL
15 mM 0.1906 mL 0.9529 mL 1.9058 mL 4.7645 mL
20 mM 0.1429 mL 0.7147 mL 1.4293 mL 3.5734 mL
25 mM 0.1143 mL 0.5717 mL 1.1435 mL 2.8587 mL
30 mM 0.0953 mL 0.4764 mL 0.9529 mL 2.3822 mL
40 mM 0.0715 mL 0.3573 mL 0.7147 mL 1.7867 mL
50 mM 0.0572 mL 0.2859 mL 0.5717 mL 1.4293 mL
60 mM 0.0476 mL 0.2382 mL 0.4764 mL 1.1911 mL
80 mM 0.0357 mL 0.1787 mL 0.3573 mL 0.8933 mL
100 mM 0.0286 mL 0.1429 mL 0.2859 mL 0.7147 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Laurolitsine(+)-NorboldineOthersInhibitorinhibitorinhibit

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