2. Dimethyl sulfone

Dimethyl sulfone (Methyl Sulfonyl Methane) is a metabolic product of endogenous methanethiol metabolism and intestinal bacterial metabolism. Dimethyl sulfone inhibits choriocapillary endothelial (CCE) cell proliferation, also has many biological effects, including antiinflammatory, antioxidant, and local anesthetic effects that could be neuroprotective.

For research use only. We do not sell to patients.

Dimethyl sulfone Chemical Structure

Dimethyl sulfone Chemical Structure

CAS No. : 67-71-0

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Based on 1 publication(s) in Google Scholar

Other Forms of Dimethyl sulfone:

Dimethyl sulfone Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Dimethyl sulfone

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Description

Dimethyl sulfone (Methyl Sulfonyl Methane) is a metabolic product of endogenous methanethiol metabolism and intestinal bacterial metabolism. Dimethyl sulfone inhibits choriocapillary endothelial (CCE) cell proliferation, also has many biological effects, including antiinflammatory, antioxidant, and local anesthetic effects that could be neuroprotective[1][2][3].

In Vitro

Dimethyl sulfone (25 mM/mL for 15.5 μL/mL; 24 h) inhibits the proliferation of cultured bovine choriocapillary endothelial (CCE) cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Dimethyl sulfone Related Antibodies
In Vivo

Dimethyl sulfone (for 0, 0.01, 0.03, 0.1, 0.3 and 1.0 mL; i.p.; single dose) shows neuroprotective effect with significant infarction volume reduction in ischemia rats[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

94.13

Formula

C2H6O2S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(C)(C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (531.18 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 10.6236 mL 53.1180 mL 106.2361 mL
5 mM 2.1247 mL 10.6236 mL 21.2472 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.60%

COA (247 KB) GC (255 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 10.6236 mL 53.1180 mL 106.2361 mL 265.5901 mL
5 mM 2.1247 mL 10.6236 mL 21.2472 mL 53.1180 mL
10 mM 1.0624 mL 5.3118 mL 10.6236 mL 26.5590 mL
15 mM 0.7082 mL 3.5412 mL 7.0824 mL 17.7060 mL
20 mM 0.5312 mL 2.6559 mL 5.3118 mL 13.2795 mL
25 mM 0.4249 mL 2.1247 mL 4.2494 mL 10.6236 mL
30 mM 0.3541 mL 1.7706 mL 3.5412 mL 8.8530 mL
40 mM 0.2656 mL 1.3280 mL 2.6559 mL 6.6398 mL
50 mM 0.2125 mL 1.0624 mL 2.1247 mL 5.3118 mL
60 mM 0.1771 mL 0.8853 mL 1.7706 mL 4.4265 mL
80 mM 0.1328 mL 0.6640 mL 1.3280 mL 3.3199 mL
100 mM 0.1062 mL 0.5312 mL 1.0624 mL 2.6559 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dimethyl sulfone67-71-0Inhibitorinhibitorinhibit

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