2. Natural Products
  3. Plants
  4. Liliaceae
  5. Veratrum nigrum Linn.

Veratrum nigrum Linn.

Veratrum nigrum Linn. (6):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-17024
    Cyclopamine 4449-51-8 99.97%
    Cyclopamine is a Hedgehog (Hh) pathway antagonist with an IC50 of 46 nM in the Hh cell assay. Cyclopamine is also a selective Smo inhibitor.
    Cyclopamine
  • HY-N6691
    Veratridine 71-62-5 99.96%
    Veratridine (3-Veratroylveracevine) is a plant neurotoxin, a voltage-gated sodium channels (VGSCs) agonist. Veratridine inhibits the peak current of Nav1.7, with an IC50 of 18.39 µM. Veratridine regulates sodium ion channels mainly by activating sodium ion channels, preventing channel inactivation and increasing sodium ion flow.
    Veratridine
  • HY-N6940
    Prosapogenin A 19057-67-1 99.87%
    Prosapogenin A, a natural product from Veratrum, induces apoptosis in human cancer cells in vitro via inhibition of the STAT3 signaling pathway and glycolysis.
    Prosapogenin A
  • HY-N0836
    Jervine 469-59-0 98.03%
    Jervine (11-Ketocyclopamine) is a potent Hedgehog (Hh) inhibitor with an IC50 of 500-700 nM. Jervine is a natural teratogenic sterodial alkaloid from rhizomes of Veratrum nigrum. Jervine has anti-inflammatory and antioxidant properties.
    Jervine
  • HY-N6243
    Veratrosine 475-00-3 ≥99.0%
    Veratramine is a steroidal alkaloid extracted from the roots and rhizomes of Veratrum californicum.
    Veratrosine
  • HY-105697
    Protoveratrine A 143-57-7
    Protoveratrine A (NSC 7526; Protalba; Protoveratrin) is an alkaloid with strong cardiostimulant and vasoconstrictive effects, which can be used in the study of hypertension and other cardiovascular diseases.
    Protoveratrine A