2. Signaling Pathways
  3. Epigenetics
  4. Small Interfering RNA (siRNA)

Small Interfering RNA (siRNA)

Small Interfering RNA (siRNA) is a small exogenous double-stranded RNA (dsRNA) (20-25 nucleotides), which triggers the RNA interference (RNAi) pathway. The short dsRNA unwinds and the sense strand is degraded. Antisense strand forms RNA induced silencing complex (RISC) with various protein components. The antisense strand retained in RISC is specifically complementary to the target gene mRNA. Meanwhile, RISC has nuclease activity, which can cut and degrade the target gene mRNA, and inhibit the expression of target gene. Incomplete complementarity results in mRNA translation inhibition.

Small Interfering RNA (siRNA) Related Products (16207):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-RS00001
    ACE2 Rat Pre-designed siRNA Set A

    ACE2 Rat Pre-designed siRNA Set A contains three designed siRNAs for ACE2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
    ACE2 Rat Pre-designed siRNA Set A
    ACE2 Rat Pre-designed siRNA Set A
  • HY-RS05137
    Fto Mouse Pre-designed siRNA Set A

    Fto Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fto gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Fto Mouse Pre-designed siRNA Set A
    Fto Mouse Pre-designed siRNA Set A
  • HY-RS01153
    ATG7 Human Pre-designed siRNA Set A

    ATG7 Human Pre-designed siRNA Set A contains three designed siRNAs for ATG7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    ATG7 Human Pre-designed siRNA Set A
    ATG7 Human Pre-designed siRNA Set A
  • HY-RS04764
    FATE1 Human Pre-designed siRNA Set A

    FATE1 Human Pre-designed siRNA Set A contains three designed siRNAs for FATE1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    FATE1 Human Pre-designed siRNA Set A
    FATE1 Human Pre-designed siRNA Set A
  • HY-RS10672
    PLD3 Human Pre-designed siRNA Set A

    PLD3 Human Pre-designed siRNA Set A contains three designed siRNAs for PLD3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    PLD3 Human Pre-designed siRNA Set A
    PLD3 Human Pre-designed siRNA Set A
  • HY-RS01188
    ATP1B3 Human Pre-designed siRNA Set A

    ATP1B3 Human Pre-designed siRNA Set A contains three designed siRNAs for ATP1B3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    ATP1B3 Human Pre-designed siRNA Set A
    ATP1B3 Human Pre-designed siRNA Set A
  • HY-RS00808
    Apc Mouse Pre-designed siRNA Set A

    Apc Mouse Pre-designed siRNA Set A contains three designed siRNAs for Apc gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Apc Mouse Pre-designed siRNA Set A
    Apc Mouse Pre-designed siRNA Set A
  • HY-RS13488
    SND1 Human Pre-designed siRNA Set A

    SND1 Human Pre-designed siRNA Set A contains three designed siRNAs for SND1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    SND1 Human Pre-designed siRNA Set A
    SND1 Human Pre-designed siRNA Set A
  • HY-RS09897
    P2RX1 Human Pre-designed siRNA Set A

    P2RX1 Human Pre-designed siRNA Set A contains three designed siRNAs for P2RX1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    P2RX1 Human Pre-designed siRNA Set A
    P2RX1 Human Pre-designed siRNA Set A
  • HY-RS15003
    TREM2 Human Pre-designed siRNA Set A

    TREM2 Human Pre-designed siRNA Set A contains three designed siRNAs for TREM2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    TREM2 Human Pre-designed siRNA Set A
    TREM2 Human Pre-designed siRNA Set A
  • HY-RS05204
    GABBR1 Human Pre-designed siRNA Set A

    GABBR1 Human Pre-designed siRNA Set A contains three designed siRNAs for GABBR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    GABBR1 Human Pre-designed siRNA Set A
    GABBR1 Human Pre-designed siRNA Set A
  • HY-RS04754
    Fasn Mouse Pre-designed siRNA Set A

    Fasn Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fasn gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Fasn Mouse Pre-designed siRNA Set A
    Fasn Mouse Pre-designed siRNA Set A
  • HY-RS08353
    METTL1 Human Pre-designed siRNA Set A
    METTL1 Human Pre-designed siRNA Set A contains three designed siRNAs for METTL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    METTL1 Human Pre-designed siRNA Set A
    METTL1 Human Pre-designed siRNA Set A
  • HY-RS09944
    P4HA3 Human Pre-designed siRNA Set A

    P4HA3 Human Pre-designed siRNA Set A contains three designed siRNAs for P4HA3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    P4HA3 Human Pre-designed siRNA Set A
    P4HA3 Human Pre-designed siRNA Set A
  • HY-RS04472
    ERBB4 Human Pre-designed siRNA Set A

    ERBB4 Human Pre-designed siRNA Set A contains three designed siRNAs for ERBB4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    ERBB4 Human Pre-designed siRNA Set A
    ERBB4 Human Pre-designed siRNA Set A
  • HY-RS16042
    ZFP36L2 Human Pre-designed siRNA Set A

    ZFP36L2 Human Pre-designed siRNA Set A contains three designed siRNAs for ZFP36L2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    ZFP36L2 Human Pre-designed siRNA Set A
    ZFP36L2 Human Pre-designed siRNA Set A
  • HY-RS06659
    Ikbkb Mouse Pre-designed siRNA Set A

    Ikbkb Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ikbkb gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Ikbkb Mouse Pre-designed siRNA Set A
    Ikbkb Mouse Pre-designed siRNA Set A
  • HY-132604
    Fazirsiran
    Fazirsiran (ARO-AAT) is a second-generation RNAi agent. Fazirsiran consistes of a cholesterol-conjugated RNAi trigger (chol-RNAi) to selectively degrade Alpha1-antitrypsin (AAT) mRNA by RNAi and a melittin-derived peptide conjugated to N-acetylgalactosamine (NAG) formulated as the excipient EX1 to promote endosomal escape of the chol-RNAi in hepatocytes. Fazirsiran can be used in the study of Alpha-1 Antitrypsin Deficiency (AATD) liver disease.
    Fazirsiran
  • HY-RS03409
    CXCR5 Human Pre-designed siRNA Set A

    CXCR5 Human Pre-designed siRNA Set A contains three designed siRNAs for CXCR5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    CXCR5 Human Pre-designed siRNA Set A
    CXCR5 Human Pre-designed siRNA Set A
  • HY-132595
    Teprasiran
    Teprasiran (QPI-1002) is a small interfering RNA that temporarily inhibits p53-mediated cell death that underlies acute kidney injury (AKI).
    Teprasiran