Small Interfering RNA (siRNA)

Small Interfering RNA (siRNA) is a small exogenous double-stranded RNA (dsRNA) (20-25 nucleotides), which triggers the RNA interference (RNAi) pathway. The short dsRNA unwinds and the sense strand is degraded. Antisense strand forms RNA induced silencing complex (RISC) with various protein components. The antisense strand retained in RISC is specifically complementary to the target gene mRNA. Meanwhile, RISC has nuclease activity, which can cut and degrade the target gene mRNA, and inhibit the expression of target gene. Incomplete complementarity results in mRNA translation inhibition.

Small Interfering RNA (siRNA) Inhibitors (9)

Small Interfering RNA (siRNA) Related Products (16207):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-RS05204

GABBR1 Human Pre-designed siRNA Set A
GABBR1 Human Pre-designed siRNA Set A contains three designed siRNAs for GABBR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

GABBR1 Human Pre-designed siRNA Set A GABBR1 Human Pre-designed siRNA Set A

HY-RS04095

Dyrk1a Mouse Pre-designed siRNA Set A
Dyrk1a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Dyrk1a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Dyrk1a Mouse Pre-designed siRNA Set A Dyrk1a Mouse Pre-designed siRNA Set A

HY-RS14923

TP63 Human Pre-designed siRNA Set A
TP63 Human Pre-designed siRNA Set A contains three designed siRNAs for TP63 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TP63 Human Pre-designed siRNA Set A TP63 Human Pre-designed siRNA Set A

HY-RS04331

ELP4 Human Pre-designed siRNA Set A
ELP4 Human Pre-designed siRNA Set A contains three designed siRNAs for ELP4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ELP4 Human Pre-designed siRNA Set A ELP4 Human Pre-designed siRNA Set A

HY-RS00212

ACSS3 Human Pre-designed siRNA Set A
ACSS3 Human Pre-designed siRNA Set A contains three designed siRNAs for ACSS3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ACSS3 Human Pre-designed siRNA Set A ACSS3 Human Pre-designed siRNA Set A

HY-RS04754

Fasn Mouse Pre-designed siRNA Set A
Fasn Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fasn gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fasn Mouse Pre-designed siRNA Set A Fasn Mouse Pre-designed siRNA Set A

HY-RS07764

LPCAT1 Human Pre-designed siRNA Set A
LPCAT1 Human Pre-designed siRNA Set A contains three designed siRNAs for LPCAT1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

LPCAT1 Human Pre-designed siRNA Set A LPCAT1 Human Pre-designed siRNA Set A

HY-RS08353

METTL1 Human Pre-designed siRNA Set A
METTL1 Human Pre-designed siRNA Set A contains three designed siRNAs for METTL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

METTL1 Human Pre-designed siRNA Set A METTL1 Human Pre-designed siRNA Set A

HY-RS09944

P4HA3 Human Pre-designed siRNA Set A
P4HA3 Human Pre-designed siRNA Set A contains three designed siRNAs for P4HA3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

P4HA3 Human Pre-designed siRNA Set A P4HA3 Human Pre-designed siRNA Set A

HY-RS04472

ERBB4 Human Pre-designed siRNA Set A
ERBB4 Human Pre-designed siRNA Set A contains three designed siRNAs for ERBB4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ERBB4 Human Pre-designed siRNA Set A ERBB4 Human Pre-designed siRNA Set A

HY-RS16042

ZFP36L2 Human Pre-designed siRNA Set A
ZFP36L2 Human Pre-designed siRNA Set A contains three designed siRNAs for ZFP36L2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ZFP36L2 Human Pre-designed siRNA Set A ZFP36L2 Human Pre-designed siRNA Set A

HY-RS06659

Ikbkb Mouse Pre-designed siRNA Set A
Ikbkb Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ikbkb gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ikbkb Mouse Pre-designed siRNA Set A Ikbkb Mouse Pre-designed siRNA Set A

HY-132604

Fazirsiran
Fazirsiran (ARO-AAT) is a second-generation RNAi agent. Fazirsiran consistes of a cholesterol-conjugated RNAi trigger (chol-RNAi) to selectively degrade Alpha1-antitrypsin (AAT) mRNA by RNAi and a melittin-derived peptide conjugated to N-acetylgalactosamine (NAG) formulated as the excipient EX1 to promote endosomal escape of the chol-RNAi in hepatocytes. Fazirsiran can be used in the study of Alpha-1 Antitrypsin Deficiency (AATD) liver disease.

HY-RS03328

CTSD Human Pre-designed siRNA Set A
CTSD Human Pre-designed siRNA Set A contains three designed siRNAs for CTSD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CTSD Human Pre-designed siRNA Set A CTSD Human Pre-designed siRNA Set A

HY-RS03409

CXCR5 Human Pre-designed siRNA Set A
CXCR5 Human Pre-designed siRNA Set A contains three designed siRNAs for CXCR5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CXCR5 Human Pre-designed siRNA Set A CXCR5 Human Pre-designed siRNA Set A

HY-RS02248

CD44 Human Pre-designed siRNA Set A
CD44 Human Pre-designed siRNA Set A contains three designed siRNAs for CD44 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CD44 Human Pre-designed siRNA Set A CD44 Human Pre-designed siRNA Set A

HY-RS05189

G3BP1 Human Pre-designed siRNA Set A
G3BP1 Human Pre-designed siRNA Set A contains three designed siRNAs for G3BP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

G3BP1 Human Pre-designed siRNA Set A G3BP1 Human Pre-designed siRNA Set A

HY-RS04160

EDF1 Human Pre-designed siRNA Set A
EDF1 Human Pre-designed siRNA Set A contains three designed siRNAs for EDF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

EDF1 Human Pre-designed siRNA Set A EDF1 Human Pre-designed siRNA Set A

HY-RS10594

PKD2L1 Human Pre-designed siRNA Set A
PKD2L1 Human Pre-designed siRNA Set A contains three designed siRNAs for PKD2L1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PKD2L1 Human Pre-designed siRNA Set A PKD2L1 Human Pre-designed siRNA Set A

HY-RS07284

KIF2C Human Pre-designed siRNA Set A
KIF2C Human Pre-designed siRNA Set A contains three designed siRNAs for KIF2C gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

KIF2C Human Pre-designed siRNA Set A KIF2C Human Pre-designed siRNA Set A

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