Angiotensin I-¹³C₅,¹⁵N (human, mouse, rat)

Cat. No.: HY-P1032S1: FAQs
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Angiotensin I-¹³C₅,¹⁵N (human, mouse, rat) is the ¹³C and ¹⁵N labeled Angiotensin I (human, mouse, rat) (HY-P1032). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice.

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Angiotensin I-<sup>13</sup>C<sub>5</sub>,<sup>15</sup>N (human, mouse, rat) Chemical Structure

Angiotensin I-¹³C₅,¹⁵N (human, mouse, rat) Chemical Structure

CAS No. : 3030398-16-1

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Other Forms of Angiotensin I-¹³C₅,¹⁵N (human, mouse, rat):

Angiotensin I (human, mouse, rat) In-stock
Angiotensin I-¹³C₁₉,¹⁵N₃ (human, mouse, rat) Get quote

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Description	Angiotensin I-¹³C₅,¹⁵N (human, mouse, rat) is the ¹³C and ¹⁵N labeled Angiotensin I (human, mouse, rat) (HY-P1032). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice^[1].
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Angiotensin I-¹³C₅,¹⁵N (human, mouse, rat) Related Antibodies
Molecular Weight	1302.43
Formula	C₅₇¹³C₅H₈₉N₁₆¹⁵NO₁₄
CAS No.	3030398-16-1
Sequence Shortening	DRVY-{Ile-13C5,15N}-HPFHL
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (258 KB) Handling Instructions (2659 KB)
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]