1. Antibodies
  2. Primary Antibodies
  3. Phospho-mTOR (Ser2481) Antibody

Phospho-mTOR (Ser2481) Antibody

Cat. No.: HY-P80838
COA User Guide for Antibodies

Phospho-mTOR (Ser2481) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 289 kDa, targeting to Phospho-mTOR (Ser2481). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

For research use only. We do not sell to patients.

Size Price Stock Quantity
Free Sample   Apply now  
10 μL $70 In-stock
50 μL $185 In-stock
100 μL $300 In-stock
250 μL   Get quote  

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

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Description

Phospho-mTOR (Ser2481) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 289 kDa, targeting to Phospho-mTOR (Ser2481). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

Background

mTOR: The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This kinase is a component of two distinct complexes, mTORC1, which controls protein synthesis, cell growth and proliferation, and mTORC2, which is a regulator of the actin cytoskeleton, and promotes cell survival and cell cycle progression. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. Inhibitors of mTOR are used in organ transplants as immunosuppressants, and are being evaluated for their therapeutic potential in SARS-CoV-2 infections. Mutations in this gene are associated with Smith-Kingsmore syndrome and somatic focal cortical dysplasia type II. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Aug 2020]

Tag

Free

Gene ID

2475

Synonyms
MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic tar
Molecular Weight

Predicted band size: 289 kDa

Purity

affinity purified

Conjugation

Non-conjugated

Research Field

Cell Biology

Product Categories

Primary Antibody; Rabbit Polyclonal Antibody

Host

Rabbit

Reactivity

Human, Mouse, Rat

SwissProt ID

P42345

Dilution Ratio

WB: 1:500-1:1,000

Application

WB

Appearance

Liquid

Formulation

Supplied in phosphate buffered saline (pH 7.4), 150 mM NaCl and 50% glycerol. Preservative: 0.02% sodium azide

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding S2481 of Human Phospho-mTOR.The exact sequence is proprietary to MCE.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Phospho-mTOR (Ser2481) Antibody
Cat. No.:
HY-P80838
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