Talaromycosis

Definition:

Talaromycosis (penicilliosis) is a life-threatening mycosis caused by the dimorphic fungus Talaromyces marneffei, which was first isolated from a bamboo rat in Vietnam in 1956. It affects primarily immunocompromised residents and travellers in southeast Asia, southern China, and northeastern India. It is a major cause of death in patients with advanced HIV infection in these areas. Infections probably occur through inhalation of T. marneffei conidia.

References:

[1]. Andrew H Limper, et al. Fungal infections in HIV/AIDS. Lancet Infect Dis. 2017 Nov;17(11):e334-e343. [Content Brief]

[2]. Cunwei Cao, et al. Talaromycosis (Penicilliosis) Due to Talaromyces (Penicillium) marneffei: Insights into the Clinical Trends of a Major Fungal Disease 60 Years After the Discovery of the Pathogen. Mycopathologia. 2019 Dec;184(6):709-720. [Content Brief]

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